Introduction
Methods
Study Population and Measurements
Statistical Analysis
Results
Variables | Overall (n = 420) | DR (n = 76) | NDR (n = 344) | P value |
---|---|---|---|---|
Age (years) | 61.7 ± 10.0 | 60.1 ± 9.6 | 62.0 ± 10.0 | 0.138 |
Gender (male, %) | 157 (37.4) | 36 (47.4) | 121 (35.2) | 0.051 |
Current smoker (yes, %) | 87 (20.7) | 14 (18.4) | 73 (21.2) | 0.642 |
Current drinker (yes, %) | 38 (9.0) | 6 (7.9) | 32 (9.3) | 0.827 |
Family history of DM (yes, %) | 111 (26.4) | 25 (32.9) | 86 (25.0) | 0.195 |
Duration of DM (years) | 4.0 (0.1–9.0) | 14.8 (10.0–20.0) | 7.0 (3.0–13.0) | < 0.001 |
HBP (yes, %) | 202 (48.1) | 43 (56.6) | 159 (46.2) | 0.128 |
Use of oral hypoglycemic agents (yes, %) | 202 (48.1) | 46 (60.5) | 156 (45.3) | 0.022 |
Use of insulin (yes, %) | 77 (18.3) | 28 (36.8) | 49 (14.2) | < 0.001 |
Exercise (yes, %) | 31 (7.4) | 3 (3.9) | 28 (8.1) | 0.33 |
Height (cm) | 163.0 (160.0–170.0) | 163.5 (159.3–172.0) | 162.5 (160.0–170.0) | 0.705 |
Weight (kg) | 68.0 (60.0–72.0) | 68.0 (60.0–72.8) | 68.0 (60.3–72.0) | 0.976 |
BMI (kg/m2) | 24.4 (23.1–26.1) | 24.0 (22.6–26.0) | 24.5 (23.2–26.3) | 0.526 |
SBP (mmHg) | 135.0 (130.0–145.0) | 140.0 (130.0–145.0) | 135.0 (130.0–145.0) | 0.497 |
DBP (mmHg) | 80.0 (76.3–90.0) | 85.0 (80.0–90.0) | 80.0 (75.3–87.8) | 0.024 |
Waist (cm) | 86.0 (82.0–90.0) | 83.0 (80.0–86.0) | 87.0 (82.0–90.0) | < 0.001 |
Hip (cm) | 98.0 (90.3–105.0) | 98.0 (92.0–105.0) | 98.0 (90.0–106.0) | 0.972 |
WHR | 0.9 (0.80–0.9) | 0.8 (0.7–0.9) | 0.9 (0.8–1.0) | 0.008 |
FPG (mmol/L) | 6.8 (5.8–8.6) | 7.3 (6.2–9.2) | 6.7 (5.8–8.3) | 0.171 |
TG (mmol/L) | 1.7 (1.3–2.2) | 1.4 (1.0–2.0) | 1.7 (1.3–2.2) | 0.054 |
TC (mmol/L) | 4.7 (4.4–5.7) | 4.5 (4.4–5.4) | 4.9 (4.4–5.6) | 0.057 |
HbA1c (%) | 6.8 (6.2–8.0) | 7.8 (6.2–9.2) | 6.7 (6.1–7.7) | 0.004 |
TC/TG ratio | 2.9 (2.1–4.0) | 3.3 (2.2–4.6) | 2.8 (2.1–4.0) | 0.016 |
n
| DR (n, %) | Model 1a | Model 2b | |||
---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |||
TC/TG | ||||||
Tertile 1, TC/TG < 2.91 | 212 | 29 (13.7) | 1 | – | 1 | – |
Tertile 2, TC/TG 2.91–4.00 | 104 | 22 (21.2) | 1.68 (0.91–3.12) | 0.098 | 2.01 (1.01–3.99) | 0.048 |
Tertile 3, TC/TG > 4.00 | 104 | 25 (24.0) | 1.92 (1.05–3.49) | 0.034 | 2.59 (1.11–3.14) | 0.011 |
P for trend = 0.027 | P for trend = 0.123 | |||||
Per SD increase in TC/TG | 420 | 76 (18.1) | 1.51 (1.19–1.91) | 0.001 | 1.39 (1.07–1.82) | 0.014 |
n
| DR (n, %) | Model 1a | Model 2b | |||
---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |||
TC | ||||||
Tertile 1, TC < 4.74 | 211 | 46 (21.8) | 1 | – | 1 | – |
Tertile 2, TC 4.74–5.74 | 104 | 14 (13.5) | 0.54 (0.28–1.05) | 0.070 | 0.53 (0.26–1.09) | 0.084 |
Tertile 3, TC > 5.74 | 105 | 16 (15.2) | 0.67 (0.34–1.25) | 0.206 | 0.57 (0.28–1.17) | 0.126 |
P for trend = 0.119 | P for trend = 0.078 | |||||
Per SD increase in TC | 420 | 76 (18.1) | 0.91 (0.71–1.17) | 0.471 | 0.86 (0.65–1.13) | 0.275 |
n
| DR (n, %) | Model 1a | Model 2b | |||
---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |||
TG | ||||||
Tertile 1, TG < 1.69 | 215 | 47 (21.9) | 1 | – | 1 | – |
Tertile 2, TG 1.69–2.20 | 102 | 15 (14.7) | 0.60 (0.32–1.15) | 0.123 | 0.61 (0.29–1.23) | 0.165 |
Tertile 3, TG > 2.20 | 103 | 14 (13.6) | 0.57 (0.29–1.11) | 0.097 | 0.57 (0.27–1.18) | 0.128 |
P for trend = 0.061 | P for trend = 0.087 | |||||
Per SD increase in TG | 420 | 76 (18.1) | 0.82 (0.59–1.12) | 0.211 | 0.84 (0.59–1.18) | 0.329 |