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Japanese Journal of Ophthalmology
Erschienen in:

02.10.2024 | Clinical Investigation

Associations of ocular anterior segment structures with sex and age: the Yamagata study (Funagata)

verfasst von: Hiroyuki Namba, Naoyuki Maeda, Makoto Tsukamoto, Hiroshi Utsunomiya, Yutaka Kaneko, Koichi Nishitsuka, Hidetoshi Yamashita, Yasuyuki Ohta, Tomohiko Usui, Masahiko Sugimoto

Erschienen in: Japanese Journal of Ophthalmology | Ausgabe 6/2024

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Abstract

Purpose

To investigate the associations of tomographic parameters in anterior segment optical coherence tomography (AS-OCT) with sex and age in a cohort study.

Study Design

A cohort design.

Materials and methods

AS-OCT data from 391 Japanese participants aged ≥ 35 years were obtained using swept-source OCT. In the cornea, the keratometric power at the flat (Kf) and steep (Ks) meridians, maximum keratometric power (Kmax), keratometric cylinder, spherical power, regular astigmatism, asymmetry, higher-order irregularity (HOI) from the anterior and posterior surfaces, and the central and thinnest corneal thicknesses were evaluated. Also, anterior chamber depth (ACD), lens thickness, crystalline lens rise (CLR), and nasal and temporal angle opening distances at 500 μm from the scleral spur (AOD500) were assessed. Sex differences and age-related changes were analyzed.

Results

Women exhibited higher anterior Kf, Ks, and Kmax and lower posterior Kf, Ks, and Kmax than men. The ACD and nasal/temporal AOD500 were shorter in women than in men. The CLR was higher in women, whereas the lens thickness did not differ between the sexes, indicating a more anteriorly positioned lens in women. Age-related changes included increased anterior/posterior HOI, increased lens thickness and CLR resulting in decreased ACD and AOD500.

Conclusion

This study reveals sex-related differences in corneal shape, anterior chamber conformation, and lens position, as well as age-related changes in tomographic parameters. ACD, CLR, nasal and temporal AOD500 showed significant sex differences in the 50–70 s, whereas lens thickness showed no difference.
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Metadaten
Titel
Associations of ocular anterior segment structures with sex and age: the Yamagata study (Funagata)
verfasst von
Hiroyuki Namba
Naoyuki Maeda
Makoto Tsukamoto
Hiroshi Utsunomiya
Yutaka Kaneko
Koichi Nishitsuka
Hidetoshi Yamashita
Yasuyuki Ohta
Tomohiko Usui
Masahiko Sugimoto
Publikationsdatum
02.10.2024
Verlag
Springer Japan
Erschienen in
Japanese Journal of Ophthalmology / Ausgabe 6/2024
Print ISSN: 0021-5155
Elektronische ISSN: 1613-2246
DOI
https://doi.org/10.1007/s10384-024-01126-7

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