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2015 | OriginalPaper | Buchkapitel

8. Assoziierte Erkrankungen bei Typ-1-Diabetes

verfasst von : Prof. Dr. med. Thomas Danne, Prof. Dr. med. Olga Kordonouri, Prof. Dr. rer. nat. Karin Lange

Erschienen in: Diabetes bei Kindern und Jugendlichen

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Autoimmunerkrankungen wie Typ-1-Diabetes, Zöliakie, Autoimmunthyreoiditis, Morbus Basedow, Morbus Addison, Vitiligo, Alopezie, Hypogonadismus oder perniziöse Anämie treten häufig im Zusammenhang miteinander auf. Bei Kindern und Jugendlichen mit Typ-1-Diabetes ist das Risiko, an einer Autoimmunthyreoiditis oder an einer Zöliakie zu erkranken, 5- bis 10-mal höher als in der Normalbevölkerung. Zöliakie und Autoimmunthyreoiditis verlaufen bei Kindern und Jugendlichen mit Typ-1-Diabetes oft ohne eindeutige klinischen Symptome. Daher sind Screeninguntersuchungen zur Früherkennung und rechtzeitigen Behandlung von großer Bedeutung. Der Nachweis von organspezifischen Autoantikörpern (z.B. Schilddrüse: Anti-TPO-AK, Anti-TG, TRAK; Zöliakie: Tg-IgA-AK) identifiziert Patienten mit einem erhöhten Risiko für eine klinisch manifeste Autoimmunerkrankung der Schilddrüse oder eine Zöliakie.
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Metadaten
Titel
Assoziierte Erkrankungen bei Typ-1-Diabetes
verfasst von
Prof. Dr. med. Thomas Danne
Prof. Dr. med. Olga Kordonouri
Prof. Dr. rer. nat. Karin Lange
Copyright-Jahr
2015
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-24645-6_8

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