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Journal of Assisted Reproduction and Genetics

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23.10.2017 | Commentary

At the dawn of personalized reproductive medicine: opportunities and challenges with incorporating multigene panel testing into fertility care

verfasst von: Piraye Yurttas Beim, David-Emlyn Parfitt, Lei Tan, Elaine A. Sugarman, Tina Hu-Seliger, Caterina Clementi, Brynn Levy

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 12/2017

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Excerpt

Advances in genomics are revolutionizing how diseases are prevented, diagnosed, and treated, across all fields of medicine. In reproductive medicine, genomic technologies are used for carrier, embryo, and prenatal screening. However, to date, genetic information has not been widely utilized for guiding treatment decisions or identifying individuals at risk for reproductive conditions, including those that can lead to infertility and early menopause. In contrast, analysis of genetic biomarkers is now the standard of care in oncology [1]. Today, oncologists routinely categorize tumors based on genetic signatures and refine their treatment strategies accordingly. This targeted approach to more personalized treatment has led to significantly higher progression-free survival rates when compared to the outcomes of conventional therapies [2]. Knowledge of patients’ genetic risk factors has also decreased patient morbidity and mortality by more precisely revealing individuals who would benefit from preventative cancer screenings such as colonoscopies or mammograms. …

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Titel: At the dawn of personalized reproductive medicine: opportunities and challenges with incorporating multigene panel testing into fertility care
verfasst von: Piraye Yurttas Beim
David-Emlyn Parfitt
Lei Tan
Elaine A. Sugarman
Tina Hu-Seliger
Caterina Clementi
Brynn Levy
Publikationsdatum: 23.10.2017
Verlag: Springer US
Erschienen in: Journal of Assisted Reproduction and Genetics / Ausgabe 12/2017
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-017-1068-2

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At the dawn of personalized reproductive medicine: opportunities and challenges with incorporating multigene panel testing into fertility care

Excerpt

Neu im Fachgebiet Gynäkologie und Geburtshilfe

Hochrisiko-Eingriffe für postoperative Übelkeit

Adjuvante Brustkrebstherapie: Doppelt hält besser

Manche Gestagene können das Risiko für Meningeome erhöhen

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Gynäkologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Excerpt

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