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Familial Cancer

Erschienen in:

17.12.2016 | Short Communication

ATM mutations for surgeons

verfasst von: Sara A. Mansfield, Robert Pilarski, Doreen M. Agnese

Erschienen in: Familial Cancer | Ausgabe 3/2017

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Abstract

The ataxia-telangiectasia mutated (ATM) gene encodes a protein kinase involved in DNA repair. Heterozygotic carriers are at an increased risk of developing breast cancer. As the use of genetic testing increases, identification of at-risk patients will also increase. The aim of this study is to review two cases of heterozygous ATM mutation carriers and review the literature to clarify the cancer risks and suggested management for breast surgeons who will be intimately involved in the care of these patients.

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Titel: ATM mutations for surgeons
verfasst von: Sara A. Mansfield
Robert Pilarski
Doreen M. Agnese
Publikationsdatum: 17.12.2016
Verlag: Springer Netherlands
Erschienen in: Familial Cancer / Ausgabe 3/2017
Print ISSN: 1389-9600
Elektronische ISSN: 1573-7292
DOI: https://doi.org/10.1007/s10689-016-9959-4

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