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Drugs & Aging

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13.11.2018 | Letter to the Editor

Authors’ Reply to Kahlaee et al: “A Systematic Review and Meta-Analyses of the Association Between Anti-hypertensive Classes and the Risk of Falls Among Older Adults”

verfasst von: Ka Keat Lim, Hui Ting Ang, Yu Heng Kwan, Chuen Seng Tan, Truls Ostbye, Lian Leng Low

Erschienen in: Drugs & Aging | Ausgabe 1/2019

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Excerpt

We recently performed a systematic review and meta-analyses to examine the associations between antihypertensive classes and three types of fall outcomes: falls, injurious falls and recurrent falls [1]. Past systematic reviews have not shown a consistent association between antihypertensive classes and fall outcomes, and we wanted to take advantage of recent studies with large samples to address this issue. Kahlaee et al. [2] studied a similar topic and sought two clarifications from us: whether we pooled hazard ratios (HRs) and odds ratios (ORs) and whether we considered time–risk analyses (i.e. the association between initiation of antihypertensive medications at various time intervals and falls), similar to the analyses they performed. We would like to respond to their letter here. …

Ang HT, Lim KK, Kwan YH, Tan PS, Yap KZ, Banu Z, et al. A systematic review and meta-analyses of the association between anti-hypertensive classes and the risk of falls among older adults. Drugs Aging. 2018;35(7):625–35.CrossRefPubMed

Kahlaee HR, Latt MD, Schneider CR. Association between chronic or acute use of antihypertensive class of medications and falls in older adults. A systematic review and meta-analysis. Am J Hypertens. 2018;31(4):467–79.CrossRefPubMed

Ham AC, Swart KM, Enneman AW, van Dijk SC, Oliai Araghi S, van Wijngaarden JP, et al. Medication-related fall incidents in an older, ambulant population: the B-PROOF study. Drugs Aging. 2014;31(12):917–27.CrossRefPubMed

Hasegawa J, Kuzuya M, Iguchi A. Urinary incontinence and behavioral symptoms are independent risk factors for recurrent and injurious falls, respectively, among residents in long-term care facilities. Arch Gerontol Geriatr. 2010;50(1):77–81.CrossRefPubMed

Eriksson S, Gustafson Y, Lundin-Olsson L. Risk factors for falls in people with and without a diagnose of dementia living in residential care facilities: a prospective study. Arch Gerontol Geriatr. 2008;46(3):293–306.CrossRefPubMed

Reid IR, Gamble GD, Grey AB, Black DM, Ensrud KE, Browner WS, et al. beta-Blocker use, BMD, and fractures in the study of osteoporotic fractures. J Bone Miner Res. 2005;20(4):613–8.CrossRefPubMed

Tinetti ME, Han L, Lee DS, McAvay GJ, Peduzzi P, Gross CP, et al. Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults. JAMA Intern Med. 2014;174(4):588–95.CrossRefPubMedPubMedCentral

Butt DA, Mamdani M, Austin PC, Tu K, Gomes T, Glazier RH. The risk of falls on initiation of antihypertensive drugs in the elderly. Osteoporos Int J Establ Result Coop Between Eur Found Osteoporos Natl Osteoporos Found USA. 2013;24(10):2649–57.CrossRef

Gribbin J, Hubbard R, Gladman JR, Smith C, Lewis S. Risk of falls associated with antihypertensive medication: population-based case-control study. Age Ageing. 2010;39(5):592–7.CrossRefPubMed

Titel: Authors’ Reply to Kahlaee et al: “A Systematic Review and Meta-Analyses of the Association Between Anti-hypertensive Classes and the Risk of Falls Among Older Adults”
verfasst von: Ka Keat Lim
Hui Ting Ang
Yu Heng Kwan
Chuen Seng Tan
Truls Ostbye
Lian Leng Low
Publikationsdatum: 13.11.2018
Verlag: Springer International Publishing
Erschienen in: Drugs & Aging / Ausgabe 1/2019
Print ISSN: 1170-229X
Elektronische ISSN: 1179-1969
DOI: https://doi.org/10.1007/s40266-018-0608-5

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Authors’ Reply to Kahlaee et al: “A Systematic Review and Meta-Analyses of the Association Between Anti-hypertensive Classes and the Risk of Falls Among Older Adults”

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