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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 9/2016

22.11.2014 | Knee

Autograft soaking in vancomycin reduces the risk of infection after anterior cruciate ligament reconstruction

verfasst von: Daniel Pérez-Prieto, Raúl Torres-Claramunt, Pablo E. Gelber, Tamer M. A. Shehata, Xavier Pelfort, Joan Carles Monllau

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 9/2016

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Abstract

Purpose

To determine whether the bathing of an anterior cruciate ligament (ACL) autograft in vancomycin reduces the rate of infection following an ACL reconstruction.

Methods

Retrospective analysis of all ACL reconstructions over an 8-year period in two University Hospitals. In the initial 4-year period, all patients were operated on under classical antibiotic intravenous prophylaxis (group 1). Over the last 4-year period, this prophylaxis was supplemented with presoaking of the autograft (group 2). Presoaking was performed with sterile gauze previously saturated with a vancomycin solution (5 mg/ml).

Results

There were 810 and 734 patients in group 1 and 2, respectively. Fifteen cases of knee joint infections were identified in the series (0.97 %). All of these infections occurred in group 1, representing a rate of infection of 1.85 % in comparison with 0 % in group 2 (p < 0.001).

Conclusions

Autograft presoaking with vancomycin in combination with classical intravenous antibiotic prophylaxis reduced the rate of knee joint infection following an ACLR in comparison with antibiotic prophylaxis alone. This technique could be of relevance in daily clinical practice to prevent infection after ACLR.

Level of evidence

Case control study, retrospective comparative study, Level III.
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Metadaten
Titel
Autograft soaking in vancomycin reduces the risk of infection after anterior cruciate ligament reconstruction
verfasst von
Daniel Pérez-Prieto
Raúl Torres-Claramunt
Pablo E. Gelber
Tamer M. A. Shehata
Xavier Pelfort
Joan Carles Monllau
Publikationsdatum
22.11.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 9/2016
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-014-3438-y

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