Introduction
Methods
Study design
MR imaging acquisition
MR imaging analysis
Statistics
Results
Study population
Variables | Median [IQR] or number |
---|---|
Sex (male/female) | 56/42 |
Age (years) | 69 [57–78] |
Weight (kg) | 73.2 [64.2–83.0] |
BMI (kg/m2) | 26.0 [22.9–28.4] |
Cardiovascular risk factors | |
Smoking (past/present/no) | 16/26/56 |
Hypertension (yes/no) | 67/31 |
Dyslipidemia (yes/no) | 63/35 |
Diabetes (yes/no) | 21/77 |
Fibrillation (yes/no) | 14/84 |
Myocardial infarct (yes/no) | 15/83 |
Peripheral artery disease (yes/no) | 8/90 |
Stroke etiologies | |
Atherosclerosis | 41 |
bEmbolic | 10 |
Dissection | 5 |
Vasculitis | 6 |
Unkown | 36 |
Stroke location | |
Anterior cerebral artery | 14 |
Middle cerebral artery | 62 |
Posterior cerebral artery | 22 |
Vascular burden | |
Fazekas score (0/1/2/3) | 20/31/30/17 |
Carotid artery stenosis ≥ 50% (yes/no) | 15*/83 |
Volume of basal ganglia and thalamus
Volume in mL | Ipsilateral to stroke n = 96 | Contralateral to stroke n = 96 | p value |
---|---|---|---|
Caudate nucleus | 4.46 ± 0.87 | 4.59 ± 0.84 | 0.14 |
Putamen | 6.08 ± 1.21 | 6.50 ± 0.90 | 0.027 |
Pallidum | 1.71 ± 0.34 | 1.79 ± 0.30 | 0.15 |
Thalamus | 6.36 ± 1.06 | 6.67 ± 0.97 | 0.058 |
% of the TIV | |||
Caudate nucleus | 0.32 ± 0.05 | 0.33 ± 0.05 | 0.13 |
Putamen | 0.44 ± 0.08 | 0.47 ± 0.06 | 0.018 |
Pallidum | 0.12 ± 0.02 | 0.13 ± 0.02 | 0.077 |
Thalamus | 0.46 ± 0.06 | 0.48 ± 0.05 | 0.016 |
Z score | |||
Caudate nucleus | 0.16 ± 1.34 | 0.48 ± 1.26 | 0.085 |
Putamen | − 0.90 ± 1.84 | − 0.22 ± 1.29 | 0.013 |
Pallidum | − 0.53 ± 1.53 | − 0.03 ± 1.17 | 0.025 |
Thalamus | − 0.61 ± 1.52 | 0.09 ± 1.32 | 0.001 |
Z scores | Ipsilateral to stroke | Contralateral to stroke | p value |
---|---|---|---|
MCA stroke | n = 61 | n = 61 | |
Caudate nucleus | − 0.03 ± 1.29 | 0.50 ± 1.20 | 0.034 |
Putamen | − 1.21 ± 1.92 | − 0.17 ± 1.26 | 0.002 |
Pallidum | − 0.67 ± 1.66 | 0.10 ± 1.17 | 0.012 |
Thalamus | − 0.72 ± 1.59 | 0.22 ± 1.35 | 0.001 |
Non-MCA stroke | n = 35 | n = 35 | |
Caudate nucleus | 0.48 ± 1.40 | 0.42 ± 1.37 | 0.90 |
Putamen | − 0.35 ± 1.57 | − 0.31 ± 1.35 | 0.96 |
Pallidum | − 0.30 ± 1.27 | − 0.25 ± 1.18 | 0.76 |
Thalamus | − 0.40 ± 1.37 | − 0.13 ± 1.28 | 0.37 |