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Clinical Autonomic Research
Erschienen in: Clinical Autonomic Research 3/2018

28.03.2018 | Review

Autonomic nervous system and cancer

verfasst von: Marta Simó, Xavier Navarro, Victor J. Yuste, Jordi Bruna

Erschienen in: Clinical Autonomic Research | Ausgabe 3/2018

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Abstract

The autonomic nervous system (ANS) is the main homeostatic regulatory system of the body. However, this widely distributed neural network can be easily affected by cancer and by the adverse events induced by cancer treatments. In this review, we have classified the ANS complications of cancer into two categories. The first includes direct cancer-related complications, such as primary ANS tumors (pheochromocytoma, paraganglioma or neuroblastoma), as well as autonomic manifestations induced by non-primary ANS tumors (primary brain tumors and metastases). The second comprises indirect ANS complications, which include autonomic features related to cancer therapy (chemotherapy, radiotherapy and/or surgery) and those not related to cancer therapy, such as paraneoplastic autonomic syndromes. We also review the molecular relationship and modulation between the ANS and the cancer cells and their microenvironment.
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Metadaten
Titel
Autonomic nervous system and cancer
verfasst von
Marta Simó
Xavier Navarro
Victor J. Yuste
Jordi Bruna
Publikationsdatum
28.03.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Autonomic Research / Ausgabe 3/2018
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-018-0523-1

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