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Current Allergy and Asthma Reports

Erschienen in:

01.11.2020 | Pediatric Allergy and Immunology (W Dolen, Section Editor)

B Cell Disorders in Children: Part II

verfasst von: Dixie D. Griffin, William K. Dolen

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 11/2020

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Abstract

Purpose of Review

B cell disorders result in decreased levels or function of immunoglobulins in an individual. Genetic mutations have been reported in a variety of B cell disorders. This review, in follow-up to a previous review, describes some rare B cell disorders as well as their known underlying genetic etiologies.

Recent Findings

Genetic studies identify and permit precise classification of an increasing number of B cell disorders, leading to a greater understanding of B cell development and function.

Summary

The B cell disorders are rare diseases. While clinicians are most familiar with X-linked agammaglobulinemia and so-called common variable immunodeficiency (CVID), there are many causes of hypogammaglobulinemia. Genetic testing provides a specific diagnosis, offers useful information for genetic counseling, and can identify previously unrecognized B cell disorders.

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Titel: B Cell Disorders in Children: Part II
verfasst von: Dixie D. Griffin
William K. Dolen
Publikationsdatum: 01.11.2020
Verlag: Springer US
Erschienen in: Current Allergy and Asthma Reports / Ausgabe 11/2020
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI: https://doi.org/10.1007/s11882-020-00963-z

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Springer Medizin

B Cell Disorders in Children: Part II

Abstract

Purpose of Review

Recent Findings

Summary

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Bilateraler Hörsturz hat eine schlechte Prognose

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Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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