Yinfang Tu and Haoyong Yu contributed equally to this work.
The author(s) declare that they have no competing interests.
Weiping JIA and Yuqian BAO contributed to the conception or design of the work; Weiping JIA contributed to final approval of the version to be published and agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved; Haoyong YU, Yinfang TU, Pin Zhang, Jianzhong DI and Xiaodong HAN contributed to the acquisition and analysis or interpretation of data for the work; Haoyong YU and Yinfang TU drafted the work or revised it critically for important intellectual content. All authors read and approved the final manuscript.
Associations between demographic data and pulmonary function have not been adequately examined in patients that underwent Roux-en-Y Gastric Bypass (RYGB). This study was designed to examine changes in body fat distribution and metabolic parameters after RYGB and whether these changes correlated with improved lung function.
A retrospective review of 32 ethnic Chinese with obesity with body mass index (BMI) 28–35 kg/m2 and type 2 diabetes (T2DM) was conducted, focusing on metabolic outcomes and pulmonary function 6 months after RYGB.
Forced expiratory volume during first second (FEV1), percentage of forced expiratory volume during first second (FEV1 [%pred]), forced vital capacity (FVC), and percentage of forced vital capacity (FVC [%pred]) all improved significantly after RYGB. These increases all were negatively correlated with decreases in body weight and visceral fat area (VFA). The improvements of FEV1, FEV1 [%pred] and FVC were also negatively correlated with baseline of body weight and VFA. Furthermore, increases in FEV1 and FVC were independently associated with baseline of VFA (β = −0.003, P = 0.000; β = −0.004, P = 0.002, respectively).
The baseline of VFA and weight loss induced by RYGB independently correlated with improved pulmonary function in Chinese patients.
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- Baseline of visceral fat area and decreased body weight correlate with improved pulmonary function after Roux-en-Y Gastric Bypass in Chinese obese patients with BMI 28–35 kg/m2 and Type 2 diabetes: a 6-month follow-up
- BioMed Central
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