Bernard (christened “Barney”) Sachs (Fig. 1) attained international renown for recognizing “amaurotic familial idiocy” or Tay–Sachs disease [6]. He was born on 2 January 1858 in Baltimore, MD, to Joseph and Sophia Sachs, an immigrant couple of Bavarian-Jewish origin. Bernard’s siblings Harry and Sam followed career paths in banking, and Julius as headmaster of the Collegiate School [7]. Julius’ son, Ernest Sachs (1879–1958), was the first Professor of Neurosurgery at Washington University [8].
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