There have been significant advances in the management of patients with gastrointestinal neuroendocrine tumors due to more accurate imaging modalities and new therapeutic agents. Complete surgical resection remains the most optimal treatment in patients with gastrointestinal neuroendocrine tumors. Preoperative imaging with DOTA peptides in patients with well-differentiated grade I and II neuroendocrine tumors is most accurate for detecting all sites of disease and has been shown to impact the selection of the most optimal treatment based on more accurate staging.
1 In some patients, DOTA peptide-based positron emission tomography (PET) imaging may show disease that is small and could be difficult to localize at the time of the operation. …