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01.12.2018 | Case report | Ausgabe 1/2018 Open Access

BMC Ophthalmology 1/2018

Bilateral acute angle-closure glaucoma following tramadol subcutaneous administration

BMC Ophthalmology > Ausgabe 1/2018
Anis Mahmoud, Fatma Abid, Imen Ksiaa, Sourour Zina, Riadh Messaoud, Moncef Khairallah



To report a case of bilateral acute angle closure-glaucoma following the use of subcutaneous Tramadol.

Case presentation

A 42-year-old healthy man with unremarkable past medical and ocular history, was admitted to the Orthopedic Department for surgical treatment of a bilateral open fracture of the femur following a road accident. Three hoursafterTramadolsubcutaneous injection, the patient complained of a bilateral acute painful visual loss with persistent vomiting. An ocular examination showed bilateral acute angle-closure-glaucoma. The patient was treated with topical anti-glaucoma therapy and intravenous Mannitol 20%.After resolution of ocular hypertension attack, NdYag laser peripheral iridotomy was performed on both eyes. After a follow-up period of 7 days visual acuity improved to 20/20 in both eyes and intraocular pressure returned to normal levels.


This case highlights the risk of developing bilateral acute angle-closure glaucoma after Tramadol administration.


Angle closure glaucomaMydriasisTramadolAnterior segment OCT
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