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Erschienen in: Intensive Care Medicine 4/2010

01.04.2010 | Brief Report

Bilevel positive airway pressure ventilation: factors influencing carbon dioxide rebreathing

verfasst von: Zbigniew Szkulmowski, Kheirallah Belkhouja, Quoc-Hung Le, Dominique Robert, Laurent Argaud

Erschienen in: Intensive Care Medicine | Ausgabe 4/2010

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Abstract

Purpose

Use of bilevel positive airway pressure (BLPAP) ventilators for noninvasive ventilation (NIV) is an established treatment for both acute and chronic ventilatory failure. Although BLPAP ventilator circuits are simpler than those of conventional ventilators, one drawback to their use is that they allow variable amounts of rebreathing to occur. The aim of this work is to measure the amount of CO2 reinsufflated in relation to the BLPAP ventilator circuit in patients, and to determine predictive factors for rebreathing.

Methods

Eighteen adult patients were ventilated on pressure support, either by intubation or with mask ventilation, during a weaning period. The mean inspiratory fraction of CO2 (tidal FiCO2) reinsufflated from the circuit between the intentional leak and the ventilator was measured for each breath. The influence of end-tidal CO2 concentration (ETCO2), respiratory rate (RR), percentage of inspiratory time (T i/T TOT), application of expiratory positive airway pressure (EPAP), and inspiratory tidal volume on magnitude of tidal FiCO2, as well as the influence of intubation versus NIV, were studied by univariate comparisons and logistic regression analysis.

Results

In a total of 11,107 cycles, tidal FiCO2 was 0.072 ± 0.173%. Of fractions measured, 8,976 (81%) were under 0.10% and 2,131 (19%) were over 0.10%, with mean values of 0.026 ± 0.027% and 0.239 ± 0.326%, respectively. ETCO2, EPAP, NIV versus intubation, and RR had significant predictive value for tidal FiCO2 >0.10%.

Conclusions

BLPAP ventilators present a specific rebreathing risk to patients. However, that risk remains modest, even in intubated patients, provided that EPAP is applied.
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Metadaten
Titel
Bilevel positive airway pressure ventilation: factors influencing carbon dioxide rebreathing
verfasst von
Zbigniew Szkulmowski
Kheirallah Belkhouja
Quoc-Hung Le
Dominique Robert
Laurent Argaud
Publikationsdatum
01.04.2010
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 4/2010
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-010-1774-z

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