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01.12.2014 | Review | Ausgabe 1/2014 Open Access

Chinese Medicine 1/2014

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Zeitschrift:
Chinese Medicine > Ausgabe 1/2014
Autoren:
Kam Lok Wong, Ricky Ngok Shun Wong, Liang Zhang, Wing Keung Liu, Tzi Bun NG, Pang Chui Shaw, Philip Chi Lip Kwok, Yau Ming Lai, Zhang Jin Zhang, Yanbo Zhang, Yao Tong, Ho-Pan Cheung, Jia Lu, Stephen Cho Wing Sze
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1749-8546-9-19) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

SCWS, YBZ, ZJZ, and YT designed and conceived the study. SCWS, RNSW, WKL, TBN and PCS, select and organize the contents of manuscript. KLW, LZ, HPC, and JL wrote the manuscript. TBN, PCLK and YML provided the constructive comments and re-wrote parts of manuscript. All authors read and approved the final version of the manuscript.

Abstract

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.
Zusatzmaterial
Authors’ original file for figure 1
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Authors’ original file for figure 2
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Authors’ original file for figure 3
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Authors’ original file for figure 4
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Authors’ original file for figure 5
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Authors’ original file for figure 6
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Authors’ original file for figure 7
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Authors’ original file for figure 8
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