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Erschienen in: Herz 1/2020

05.12.2019 | Main topic

Biomarkers in primary prevention

Meaningful diagnosis based on biomarker scores?

verfasst von: MD Christian Schulte, PhD Tanja Zeller

Erschienen in: Herz | Ausgabe 1/2020

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Abstract

Cardiovascular (CV) risk assessment is based on the utilization of risk scores, enabling clinicians to estimate an individual’s risk to develop CV pathologies and events. Such risk scores comprise classic CV risk factors such as smoking, diabetes, hypertension, and blood cholesterol levels. Recently, other CV biomarkers such as cardiac troponins have been suggested and evaluated as alternative biomarkers not only in the acute diagnostic setting of myocardial infarction, but also as markers for risk stratification in the general population. In this review, we summarize the current knowledge on biomarkers in the field of primary prevention in cardiovascular disease (CVD). Furthermore, we present potential alternative biomarker-based strategies for CV risk assessment. In this respect we provide an outlook on the potential use of genomic variation as well as circulating non-coding RNAs to complement current risk assessment strategies so as to further personalize risk stratification in CVD.
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Metadaten
Titel
Biomarkers in primary prevention
Meaningful diagnosis based on biomarker scores?
verfasst von
MD Christian Schulte
PhD Tanja Zeller
Publikationsdatum
05.12.2019
Verlag
Springer Medizin
Erschienen in
Herz / Ausgabe 1/2020
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI
https://doi.org/10.1007/s00059-019-04874-2