“Black” contrast effect on MR arthrography using new generation high-relaxivity gadolinium contrast agent at recommended doses
- 14.06.2025
- Comment
Erschienen in:
- Verfasst von
- Arthur B. Meyers
- Jean A. Tkach
- Manish N. Patel
- Jonathan R. Dillman
- Erschienen in
- Pediatric Radiology | Ausgabe 7/2025
Auszug
Over the past two decades, the discovery of gadolinium retention in various organs of the body (brain, bone, skin, and liver) related to the administration of gadolinium-based contrast agents (GBCAs) has raised concerns over the use and safety of these contrast agents [1, 2]. The clinical significance of this gadolinium retention remains unknown, but concerns persist, particularly in children whose organ systems are still developing and who may receive multiple doses of GBCAs over their lifetimes. Mithal et al. found that since the recognition of gadolinium deposition, many pediatric hospitals in North America have switched or plan to switch from linear GBCAs to macrocyclic GBCAs, specifically due to concerns about gadolinium brain deposition [3]. Furthermore, environmental studies have shown the presence of gadolinium in the water supplies of countries with highly developed healthcare systems and extensive use of MRI tests [4]. …
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- Titel
- “Black” contrast effect on MR arthrography using new generation high-relaxivity gadolinium contrast agent at recommended doses
- Verfasst von
-
Arthur B. Meyers
Jean A. Tkach
Manish N. Patel
Jonathan R. Dillman
- Publikationsdatum
- 14.06.2025
- Verlag
- Springer Berlin Heidelberg
- Erschienen in
-
Pediatric Radiology / Ausgabe 7/2025
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998 - DOI
- https://doi.org/10.1007/s00247-025-06299-y
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