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BMC Medical Research Methodology

Ausgabe 1/2017

Inhalt (181 Artikel)

Open Access Research article

Clinical prediction in defined populations: a simulation study investigating when and how to aggregate existing models

Glen P. Martin, Mamas A. Mamas, Niels Peek, Iain Buchan, Matthew Sperrin

Open Access Research article

Outcome-sensitive multiple imputation: a simulation study

Evangelos Kontopantelis, Ian R. White, Matthew Sperrin, Iain Buchan

Open Access Research article

G-computation of average treatment effects on the treated and the untreated

Aolin Wang, Roch A. Nianogo, Onyebuchi A. Arah

Open Access Research article

Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects

Maarten M. H. Lahr, Durk-Jouke van der Zee, Gert-Jan Luijckx, Patrick C. A. J. Vroomen, Erik Buskens

Open Access Research Article

Estimating a population cumulative incidence under calendar time trends

Stefan N. Hansen, Morten Overgaard, Per K. Andersen, Erik T. Parner

Open Access Erratum

Erratum to: Sample size calculations for cluster randomised controlled trials with a fixed number of clusters

Karla Hemming, Alan J Girling, Alice J Sitch, Jennifer Marsh, Richard J Lilford

Open Access Research article

Estimating cardiovascular disease incidence from prevalence: a spreadsheet based model

Xue Feng Hu, Kue Young, Hing Man Chan

Open Access Research Article

Comparison of methods for estimating the attributable risk in the context of survival analysis

Malamine Gassama, Jacques Bénichou, Laureen Dartois, Anne C. M. Thiébaut

Open Access Research article

Multiple triangulation and collaborative research using qualitative methods to explore decision making in pre-hospital emergency care

Maxine Johnson, Rachel O’Hara, Enid Hirst, Andrew Weyman, Janette Turner, Suzanne Mason, Tom Quinn, Jane Shewan, A. Niroshan Siriwardena

Open Access Research article

Estimating the size of the homeless adolescent population across seven cities in Cambodia

Lindsay Stark, Beth L. Rubenstein, Kimchoeun Pak, Rosemary Taing, Gary Yu, Sok Kosal, Leslie Roberts

Open Access Research article

Psychometric analysis of the brief symptom inventory 18 (BSI-18) in a representative German sample

Gabriele Helga Franke, Susanne Jaeger, Heide Glaesmer, Claus Barkmann, Katja Petrowski, Elmar Braehler

Open Access Research article

Measuring health-related quality of life in cervical cancer patients: a systematic review of the most used questionnaires and their validity

Casper Tax, Marlie E. Steenbergen, Petra L. M. Zusterzeel, Ruud L. M. Bekkers, Maroeska M. Rovers

Open Access Research article

Assessing and adjusting for non-response in the Millennium Cohort Family Study

Nida H. Corry, Christianna S. Williams, Mike Battaglia, Hope Seib McMaster, Valerie A. Stander

Open Access Research article

Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study

Jane Candlish, Alexander Pate, Matthew Sperrin, Tjeerd van Staa

Open Access Research article

Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination

Manas K. Akmatov, Leonhard Jentsch, Peggy Riese, Marcus May, Malik W. Ahmed, Damaris Werner, Anja Rösel, Jana Prokein, Inga Bernemann, Norman Klopp, Blair Prochnow, Thomas Illig, Christoph Schindler, Carlos A. Guzman, Frank Pessler

Open Access Erratum

Erratum to: A threshold method for immunological correlates of protection

Xuan Chen, Fabrice Bailleux, Kamal Desai, Li Qin, Andrew J. Dunning

Open Access Research Article

Efficient confidence limits for adaptive one-arm two-stage clinical trials with binary endpoints

Guogen Shan, Hua Zhang, Tao Jiang

Open Access Research article

Utilising identifier error variation in linkage of large administrative data sources

Katie Harron, Gareth Hagger-Johnson, Ruth Gilbert, Harvey Goldstein

Open Access Research article

Testing a systematic approach to identify and prioritise barriers to successful implementation of a complex healthcare intervention

Louise E. Craig, Leonid Churilov, Liudmyla Olenko, Dominique A. Cadilhac, Rohan Grimley, Simeon Dale, Cintia Martinez-Garduno, Elizabeth McInnes, Julie Considine, Jeremy M. Grimshaw, Sandy Middleton

Open Access Research article

Self-controlled designs in pharmacoepidemiology involving electronic healthcare databases: a systematic review

Nathalie Gault, Johann Castañeda-Sanabria, Yann De Rycke, Sylvie Guillo, Stéphanie Foulon, Florence Tubach

Open Access Research article

Generating evidence on a risk-based monitoring approach in the academic setting – lessons learned

Belinda von Niederhäusern, Annette Orleth, Sabine Schädelin, Nawal Rawi, Martin Velkopolszky, Claudia Becherer, Pascal Benkert, Priya Satalkar, Matthias Briel, Christiane Pauli-Magnus

Open Access Research Article

On the censored cost-effectiveness analysis using copula information

Charles Fontaine, Jean-Pierre Daurès, Paul Landais

Open Access Research article

A comparison of analytic approaches for individual patient data meta-analyses with binary outcomes

Doneal Thomas, Robert Platt, Andrea Benedetti

Open Access Research article

Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice

Stephen D. Walter, Robin M. Turner, Petra Macaskill, Kirsten J. McCaffery, Les Irwig

Open Access Research article

Participant retention practices in longitudinal clinical research studies with high retention rates

Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham, Cheryl Dennison Himmelfarb

Open Access Research article

A statistical method utilizing information of imported cases to estimate the transmissibility for an influenza pandemic

Ka Chun Chong, Benny Chung Ying Zee, Maggie Haitian Wang

Open Access Research article

Research waste in diagnostic trials: a methods review evaluating the reporting of test-treatment interventions

Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Sian Taylor-Phillips, Clare Davenport, Chris Hyde, Jonathan J. Deeks

Open Access Research article

Test-treatment RCTs are susceptible to bias: a review of the methodological quality of randomized trials that evaluate diagnostic tests

Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Alice J. Sitch, Chris Hyde, Jonathan J. Deeks

Open Access Research article

Leveraging the EHR4CR platform to support patient inclusion in academic studies: challenges and lessons learned

Yannick Girardeau, Justin Doods, Eric Zapletal, Gilles Chatellier, Christel Daniel, Anita Burgun, Martin Dugas, Bastien Rance

Open Access Research article

A systematic review of studies with a representative sample of refugees and asylum seekers living in the community for participation in mental health research

Joanne C. Enticott, Frances Shawyer, Shiva Vasi, Kimberly Buck, I-Hao Cheng, Grant Russell, Ritsuko Kakuma, Harry Minas, Graham Meadows

Open Access Research article

AIMD - a validated, simplified framework of interventions to promote and integrate evidence into health practices, systems, and policies

Peter Bragge, Jeremy M. Grimshaw, Cynthia Lokker, Heather Colquhoun, Lauren Albrecht, Justine Baron, Ann Dadich, Laura Damschroder, Kristin Danko, Maria E. Fernandez, Signe Agnes Flottorp, Heather L. Gainforth, Kate Gooding, Ian D. Graham, Susanne Hempel, Simon Kitto, Jennifer Leeman, Danielle Mazza, Ann McKibbon, Susan Michie, Teryl Nuckols, John Ovretveit, Gjalt-Jorn Y. Peters, Hugo Sax, Shannon D. Scott, Kathleen R. Stevens, Michael G. Wilson

Open Access Research article

Trial Sequential Analysis in systematic reviews with meta-analysis

Jørn Wetterslev, Janus Christian Jakobsen, Christian Gluud

Open Access Research article

Why sample selection matters in exploratory factor analysis: implications for the 12-item World Health Organization Disability Assessment Schedule 2.0

Cadeyrn J. Gaskin, Sylvie D. Lambert, Steven J. Bowe, Liliana Orellana

Open Access Research article

The feasibility of matching on a propensity score for acupuncture in a prospective cohort study of patients with chronic pain

Eric S. Johnson, John F. Dickerson, William M. Vollmer, Alee M. Rowley, Cheryl Ritenbaugh, Richard A. Deyo, Lynn DeBar

Open Access Correspondence

Implementation of clinical research trials using web-based and mobile devices: challenges and solutions

Roy Eagleson, Luis Altamirano-Diaz, Alex McInnis, Eva Welisch, Stefanie De Jesus, Harry Prapavessis, Meghan Rombeek, Jamie A. Seabrook, Teresa Park, Kambiz Norozi

Open Access Research article

Standardizing effect size from linear regression models with log-transformed variables for meta-analysis

Miguel Rodríguez-Barranco, Aurelio Tobías, Daniel Redondo, Elena Molina-Portillo, María José Sánchez

Open Access Research article

Incorporating nonlinearity into mediation analyses

George J. Knafl, Kathleen A. Knafl, Margaret Grey, Jane Dixon, Janet A. Deatrick, Agatha M. Gallo

Open Access Research article

Methods for conceptualising ‘visual ability’ as a measurable construct in children with cerebral palsy

Belinda Deramore Denver, Margareta Adolfsson, Elspeth Froude, Peter Rosenbaum, Christine Imms

Open Access Erratum

Erratum to: Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study

Jane Candlish, Alexander Pate, Matthew Sperrin, Tjeerd van Staa

Open Access Research article

The effect of postal questionnaire burden on response rate and answer patterns following admission to intensive care: a randomised controlled trial

Robert Hatch, Duncan Young, Vicki Barber, David A Harrison, Peter Watkinson

Open Access Correspondence

Practical partnered research to improve weight loss among overweight/obese veterans: lessons from the trenches

Mona AuYoung, Laura J. Damschroder, Linda Kinsinger, Tannaz Moin, Caroline R. Richardson

Open Access Research Article

The importance of censoring in competing risks analysis of the subdistribution hazard

Mark W. Donoghoe, Val Gebski

Open Access Research article

Time-dependent ROC curve analysis in medical research: current methods and applications

Adina Najwa Kamarudin, Trevor Cox, Ruwanthi Kolamunnage-Dona

Open Access Research Article

Comparison of surveillance-based metrics for the assessment and monitoring of disease detection: simulation study about type 2 diabetes

Ralph Brinks, Annika Hoyer, Deborah B. Rolka, Oliver Kuss, Edward W. Gregg

Open Access Research article

Estimating the standardized incidence ratio (SIR) with incomplete follow-up data

Heiko Becher, Volker Winkler

Open Access Research article

Practical application of opt-out recruitment methods in two health services research studies

Christopher J. Miller, James F. Burgess Jr., Ellen P. Fischer, Deborah J. Hodges, Lindsay K. Belanger, Jessica M. Lipschitz, Siena R. Easley, Christopher J. Koenig, Regina L. Stanley, Jeffrey M. Pyne

Open Access Research article

Statistical evaluation of adding multiple risk factors improves Framingham stroke risk score

Xiao-Hua Zhou, Xiaonan Wang, Ashlee Duncan, Guizhou Hu, Jiayin Zheng

Open Access Research article

Clinical patient registry recruitment and retention: a survey of patients in two chronic disease registries

Daniel H. Solomon, Nancy A. Shadick, Michael E. Weinblatt, Michelle Frits, Christine Iannaccone, Agnes Zak, Joshua R. Korzenik

Open Access Research article

Review and evaluation of performance measures for survival prediction models in external validation settings

M. Shafiqur Rahman, Gareth Ambler, Babak Choodari-Oskooei, Rumana Z. Omar

Open Access Study protocol

Protocol for the development of a salutogenic intrapartum core outcome set (SIPCOS)

Valerie Smith, Deirdre Daly, Ingela Lundgren, Tine Eri, Cecily Begley, Mechthild M. Gross, Soo Downe, Zarko Alfirevic, Declan Devane

Open Access Research article

Kappa statistic to measure agreement beyond chance in free-response assessments

Marc Carpentier, Christophe Combescure, Laura Merlini, Thomas V. Perneger

Open Access Research article

Impact of correlation of predictors on discrimination of risk models in development and external populations

Suman Kundu, Madhu Mazumdar, Bart Ferket

Open Access Research article

The impact of the mode of survey administration on estimates of daily smoking for mobile phone only users

Joseph Hanna, Damien V. Cordery, David G. Steel, Walter Davis, Timothy C. Harrold

Open Access Research article

Does the association between adherence to statin medications and mortality depend on measurement approach? A retrospective cohort study

Mhd. Wasem Alsabbagh, Dean Eurich, Lisa M. Lix, Thomas W. Wilson, David F. Blackburn

Open Access Research article

Treatment-seeking behaviour in low- and middle-income countries estimated using a Bayesian model

Victor A. Alegana, Jim Wright, Carla Pezzulo, Andrew J. Tatem, Peter M. Atkinson

Open Access Research article

Assessing the impact of natural policy experiments on socioeconomic inequalities in health: how to apply commonly used quantitative analytical methods?

Yannan Hu, Frank J. van Lenthe, Rasmus Hoffmann, Karen van Hedel, Johan P. Mackenbach

Open Access Research article

Evaluation of a modified version of the Posttraumatic Growth Inventory-Short Form

Navjot Kaur, Ben Porter, Cynthia A. LeardMann, Laura E. Tobin, Hector Lemus, David D. Luxton, Richard Armenta, Lauren Bauer, Deb Bookwalter, Anna Bukowinski, Adam Cooper, James Davies, Alex Esquivel, Dennis Faix, Susan Farrish, Toni Rose Geronimo, Gia Gumbs, Isabel Jacobson, Claire Kolaja, Joyce Kong, William Lee, Kyna Long, Denise Lovec-Jenkins, Gordon Lynch, Rayna Matsuno, Danielle Mitchell, Kristin Motylinski, Anna Nagel, Chiping Nieh, Chris O’Malley, Serguey Parkhomovsky, Anet Petrosyan, Chris Phillips, Teresa Powell, Rudy Rull, Beverly Sheppard, Steven Speigle, Daniel Trone, Jennifer Walstrom, Paul Amoroso, Edward Boyko, Gary Gackstetter, Greg Gray, Tomoko Hooper, Margaret Ryan, Tyler Smith, Timothy Wells

Open Access Research article

Using evaluability assessment to assess local community development health programmes: a Scottish case-study

Melissa Belford, Tony Robertson, Ruth Jepson

Open Access Research article

Evaluation of the impact of disease prevention measures: a methodological note on defining incidence rates

Yin-Bun Cheung, Ying Xu, Matthew Cairns, Paul Milligan

Open Access Research article

An experimental comparison of web-push vs. paper-only survey procedures for conducting an in-depth health survey of military spouses

Hope Seib McMaster, Cynthia A. LeardMann, Steven Speigle, Don A. Dillman, Valerie Stander, Jackie Pflieger, Carlos Carballo, Teresa Powell, Kelly Woodall, Evelyn Sun, Lauren Bauer, William Lee, Nida Corry, Christianna Williams, John Fairbank, Robert Murphy, Ernestine Briggs-King, Ellen Gerrity, Robert Lee

Open Access Research article

Measurement properties of the Danish version of the Awareness and Beliefs about Cancer (ABC) measure

Line Hvidberg, Anette Fischer Pedersen, Christian Nielsen Wulff, Anders Helles Carlsen, Peter Vedsted

Open Access Research article

Sample size and power determination when limited preliminary information is available

Christine E. McLaren, Wen-Pin Chen, Thomas D. O’Sullivan, Daniel L. Gillen, Min-Ying Su, Jeon H. Chen, Bruce J. Tromberg

Open Access Technical advance

Assessing the complexity of interventions within systematic reviews: development, content and use of a new tool (iCAT_SR)

Simon Lewin, Maggie Hendry, Jackie Chandler, Andrew D. Oxman, Susan Michie, Sasha Shepperd, Barnaby C. Reeves, Peter Tugwell, Karin Hannes, Eva A. Rehfuess, Vivien Welch, Joanne E. Mckenzie, Belinda Burford, Jennifer Petkovic, Laurie M. Anderson, Janet Harris, Jane Noyes

Open Access Research article

The effectiveness of a monetary incentive offer on survey response rates and response completeness in a longitudinal study

Shengchao Yu, Howard E. Alper, Angela-Maithy Nguyen, Robert M. Brackbill, Lennon Turner, Deborah J. Walker, Carey B. Maslow, Kimberly C. Zweig

Open Access Research article

Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance

Tri-Long Nguyen, Gary S. Collins, Jessica Spence, Jean-Pierre Daurès, P. J. Devereaux, Paul Landais, Yannick Le Manach

Open Access Research Article

On comparison of net survival curves

Klemen Pavlič, Maja Pohar Perme

Open Access Research article

On the impact of nonresponse in logistic regression: application to the 45 and Up study

Joanna J. J. Wang, Mark Bartlett, Louise Ryan

Open Access Research article

Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice

Lewis Cooney, Yoon K. Loke, Su Golder, Jamie Kirkham, Andrea Jorgensen, Ian Sinha, Daniel Hawcutt

Open Access Research article

Validity of self-reported weight and height: a cross-sectional study among Malaysian adolescents

C. C. Kee, K. H. Lim, M. G. Sumarni, C. H. Teh, Y. Y. Chan, M. I. Nuur Hafizah, Y. K. Cheah, E. O. Tee, Y. Ahmad Faudzi, M. Amal Nasir

Open Access Research article

Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies

Marie-jeanne Buscot, Simon S. Wotherspoon, Costan G. Magnussen, Markus Juonala, Matthew A. Sabin, David P. Burgner, Terho Lehtimäki, Jorma S. A. Viikari, Nina Hutri-Kähönen, Olli T. Raitakari, Russell J. Thomson

Open Access Research Article

A nonparametric multiple imputation approach for missing categorical data

Muhan Zhou, Yulei He, Mandi Yu, Chiu-Hsieh Hsu

Open Access Research article

Methodologic considerations in the design and analysis of nested case-control studies: association between cytokines and postoperative delirium

Long H. Ngo, Sharon K. Inouye, Richard N. Jones, Thomas G. Travison, Towia A. Libermann, Simon T. Dillon, George A. Kuchel, Sarinnapha M. Vasunilashorn, David C. Alsop, Edward R. Marcantonio

Open Access Research article

Limitations of pulmonary embolism ICD-10 codes in emergency department administrative data: let the buyer beware

Kristin Burles, Grant Innes, Kevin Senior, Eddy Lang, Andrew McRae

Open Access Research Article

Simulation of complex data structures for planning of studies with focus on biomarker comparison

Andreas Schulz, Daniela Zöller, Stefan Nickels, Manfred E. Beutel, Maria Blettner, Philipp S. Wild, Harald Binder

Open Access Erratum

Erratum to: Standardizing effect size from linear regression models with log-transformed variables for meta-analysis

Miguel Rodríguez-Barranco, Aurelio Tobías, Daniel Redondo, Elena Molina-Portillo, María José Sánchez

Open Access Research Article

A DAG-based comparison of interventional effect underestimation between composite endpoint and multi-state analysis in cardiovascular trials

Antje Jahn-Eimermacher, Katharina Ingel, Stella Preussler, Antoni Bayes-Genis, Harald Binder

Open Access Research article

Inverse probability of treatment-weighted competing risks analysis: an application on long-term risk of urinary adverse events after prostate cancer treatments

Charlotte A. Bolch, Haitao Chu, Stephanie Jarosek, Stephen R. Cole, Sean Elliott, Beth Virnig

Open Access Research article

Selection bias and subject refusal in a cluster-randomized controlled trial

Rochelle Yang, Barry L. Carter, Tyler H. Gums, Brian M. Gryzlak, Yinghui Xu, Barcey T. Levy

Open Access Research article

Estimating parameters for probabilistic linkage of privacy-preserved datasets

Adrian P. Brown, Sean M. Randall, Anna M. Ferrante, James B. Semmens, James H. Boyd

Open Access Research article

Barriers to publishing in biomedical journals perceived by a sample of French researchers: results of the DIAzePAM study

Martin Duracinsky, Christophe Lalanne, Laurence Rous, Aichata Fofana Dara, Lesya Baudoin, Claire Pellet, Alexandre Descamps, Fabienne Péretz, Olivier Chassany

Open Access Research article

Inter-rater reliability of AMSTAR is dependent on the pair of reviewers

Dawid Pieper, Anja Jacobs, Beate Weikert, Alba Fishta, Uta Wegewitz

Open Access Research article

Awareness of wearing an accelerometer does not affect physical activity in youth

Jérémy Vanhelst, Laurent Béghin, Elodie Drumez, Stéphanie Coopman, Frédéric Gottrand

Open Access Research article

Implementation fidelity of a self-management course for epilepsy: method and assessment

G. Wojewodka, S. Hurley, S. J. C. Taylor, A. J. Noble, L. Ridsdale, L. H. Goldstein

Open Access Research article

Cost and yield considerations when expanding recruitment for genetic studies: the primary open-angle African American glaucoma genetics study

Rebecca Salowe, Laura O’Keefe, Sayaka Merriam, Roy Lee, Naira Khachatryan, Prithvi Sankar, Eydie Miller-Ellis, Amanda Lehman, Victoria Addis, Windell Murphy, Jeffrey Henderer, Maureen Maguire, Joan O’Brien

Open Access Technical advance

Sample size re-estimation in paired comparative diagnostic accuracy studies with a binary response

Gareth P. J. McCray, Andrew C. Titman, Paula Ghaneh, Gillian A. Lancaster

Open Access Research article

Accounting for treatment use when validating a prognostic model: a simulation study

Romin Pajouheshnia, Linda M. Peelen, Karel G. M. Moons, Johannes B. Reitsma, Rolf H. H. Groenwold

Open Access Research article

Using structural equation modeling for network meta-analysis

Yu-Kang Tu, Yun-Chun Wu

Open Access Research Article

Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer

Solène Desmée, France Mentré, Christine Veyrat-Follet, Bernard Sébastien, Jérémie Guedj

Open Access Debate

Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study

F. Lauzier, N. K. Adhikari, A. Seely, K. K. Y. Koo, E. P. Belley-Côté, K. E. A. Burns, D. J. Cook, F. D’Aragon, B. Rochwerg, M. E. Kho, S. J. W. Oczkowksi, E. H. Duan, M. O. Meade, A. G. Day, F. Lamontagne

Open Access Research Article

A random effects meta-analysis model with Box-Cox transformation

Yusuke Yamaguchi, Kazushi Maruo, Christopher Partlett, Richard D. Riley

Open Access Research Article

Basic parametric analysis for a multi-state model in hospital epidemiology

Maja von Cube, Martin Schumacher, Martin Wolkewitz

Open Access Research Article

Implementing the EffTox dose-finding design in the Matchpoint trial

Kristian Brock, Lucinda Billingham, Mhairi Copland, Shamyla Siddique, Mirjana Sirovica, Christina Yap

Open Access Research article

Integrating data from randomized controlled trials and observational studies to predict the response to pregabalin in patients with painful diabetic peripheral neuropathy

Joe Alexander, Roger A. Edwards, Alberto Savoldelli, Luigi Manca, Roberto Grugni, Birol Emir, Ed Whalen, Stephen Watt, Marina Brodsky, Bruce Parsons

Open Access Research article

A comparison of multiple imputation methods for handling missing values in longitudinal data in the presence of a time-varying covariate with a non-linear association with time: a simulation study

Anurika Priyanjali De Silva, Margarita Moreno-Betancur, Alysha Madhu De Livera, Katherine Jane Lee, Julie Anne Simpson

Open Access Research article

Programme Reporting Standards (PRS) for improving the reporting of sexual, reproductive, maternal, newborn, child and adolescent health programmes

Anna E. Kågesten, Özge Tunçalp, Anayda Portela, Moazzam Ali, Nhan Tran, A. Metin Gülmezoglu

Open Access Research article

Validity and reliability of a Malay version of the brief illness perception questionnaire for patients with type 2 diabetes mellitus

Boon-How Chew, Rimke C. Vos, Monique Heijmans, Sazlina Shariff-Ghazali, Aaron Fernandez, Guy E. H. M. Rutten

Open Access Research Article

Choice of futility boundaries for group sequential designs with two endpoints

Svenja Schüler, Meinhard Kieser, Geraldine Rauch

Open Access Research article

Using classification and regression tree modelling to investigate response shift patterns in dentine hypersensitivity

Carolina Machuca, Mario V. Vettore, Marta Krasuska, Sarah R. Baker, Peter G. Robinson

Open Access Research article

Trading certainty for speed - how much uncertainty are decisionmakers and guideline developers willing to accept when using rapid reviews: an international survey

Gernot Wagner, Barbara Nussbaumer-Streit, Judith Greimel, Agustín Ciapponi, Gerald Gartlehner

Open Access Research article

Applied Swarm-based medicine: collecting decision trees for patterns of algorithms analysis

Cédric M. Panje, Markus Glatzer, Joscha von Rappard, Christian Rothermundt, Thomas Hundsberger, Valentin Zumstein, Ludwig Plasswilm, Paul Martin Putora

Open Access Research article

Estimating correlation between multivariate longitudinal data in the presence of heterogeneity

Feng Gao, J. Philip Miller, Chengjie Xiong, Jingqin Luo, Julia A. Beiser, Ling Chen, Mae O. Gordon

Open Access Research article

The impact of self-interviews on response patterns for sensitive topics: a randomized trial of electronic delivery methods for a sexual behaviour questionnaire in rural South Africa

Guy Harling, Dumile Gumede, Tinofa Mutevedzi, Nuala McGrath, Janet Seeley, Deenan Pillay, Till W. Bärnighausen, Abraham J. Herbst

Open Access Research article

Statistical methods for elimination of guarantee-time bias in cohort studies: a simulation study

In Sung Cho, Ye Rin Chae, Ji Hyeon Kim, Hae Rin Yoo, Suk Yong Jang, Gyu Ri Kim, Chung Mo Nam

Open Access Research article

Using Bayesian statistics to estimate the likelihood a new trial will demonstrate the efficacy of a new treatment

David J. Biau, Samuel Boulezaz, Laurent Casabianca, Moussa Hamadouche, Philippe Anract, Sylvie Chevret

Open Access Research article

Trends in the number and the quality of trial protocols involving children submitted to a French Institutional Review Board

Isabelle Gautier, Perrine Janiaud, Nelly Rollet, Nicolas André, Michel Tsimaratos, Catherine Cornu, Salma Malik, Stéphanie Gentile, Behrouz Kassaï

Open Access Research article

Validity and reliability of a performance evaluation tool based on the modified Barthel Index for stroke patients

Tomoko Ohura, Kimitaka Hase, Yoshie Nakajima, Takeo Nakayama

Open Access Research article

Factors associated with attrition in a longitudinal online study: results from the HaBIDS panel

Nicole Rübsamen, Manas K. Akmatov, Stefanie Castell, André Karch, Rafael T. Mikolajczyk

Open Access Research article

Longitudinal studies that use data collected as part of usual care risk reporting biased results: a systematic review

Delaram Farzanfar, Asmaa Abumuamar, Jayoon Kim, Emily Sirotich, Yue Wang, Eleanor Pullenayegum

Open Access Research article

Multiple imputation for handling missing outcome data when estimating the relative risk

Thomas R. Sullivan, Katherine J. Lee, Philip Ryan, Amy B. Salter

Open Access Research article

Evidence mapping based on systematic reviews of therapeutic interventions for gastrointestinal stromal tumors (GIST)

Mónica Ballesteros, Nadia Montero, Antonio López-Pousa, Gerard Urrútia, Ivan Solà, Gabriel Rada, Hector Pardo-Hernandez, Xavier Bonfill

Open Access Research article

Addressing data privacy in matched studies via virtual pooling

P. Saha-Chaudhuri, C.R. Weinberg

Open Access Research article

Monte Carlo simulation-based estimation for the minimum mortality temperature in temperature-mortality association study

Whanhee Lee, Ho Kim, Sunghee Hwang, Antonella Zanobetti, Joel D. Schwartz, Yeonseung Chung

Open Access Correspondence

Conducting a team-based multi-sited focused ethnography in primary care

A.P. Bikker, H. Atherton, H. Brant, T. Porqueddu, J.L. Campbell, A. Gibson, B. McKinstry, C. Salisbury, S. Ziebland

Open Access Research article

Measuring the burden of treatment for chronic disease: implications of a scoping review of the literature

Adem Sav, Asiyeh Salehi, Frances S. Mair, Sara S. McMillan

Open Access Research article

Assessment of consent models as an ethical consideration in the conduct of prehospital ambulance randomised controlled clinical trials: a systematic review

Stephanie Armstrong, Adele Langlois, Despina Laparidou, Mark Dixon, Jason P. Appleton, Philip M. Bath, Helen Snooks, A. Niroshan Siriwardena

Open Access Research article

Repeat: a framework to assess empirical reproducibility in biomedical research

Leslie D. McIntosh, Anthony Juehne, Cynthia R. H. Vitale, Xiaoyan Liu, Rosalia Alcoser, J. Christian Lukas, Bradley Evanoff

Open Access Research article

Pragmatic clinical trials embedded in healthcare systems: generalizable lessons from the NIH Collaboratory

Kevin P. Weinfurt, Adrian F. Hernandez, Gloria D. Coronado, Lynn L. DeBar, Laura M. Dember, Beverly B. Green, Patrick J. Heagerty, Susan S. Huang, Kathryn T. James, Jeffrey G. Jarvik, Eric B. Larson, Vincent Mor, Richard Platt, Gary E. Rosenthal, Edward J. Septimus, Gregory E. Simon, Karen L. Staman, Jeremy Sugarman, Miguel Vazquez, Douglas Zatzick, Lesley H. Curtis

Open Access Research article

Patients’ beliefs regarding informed consent for low-risk pragmatic trials

Rafael Dal-Ré, Antonio J. Carcas, Xavier Carné, David Wendler

Open Access Research article

Systematic review of statistical approaches to quantify, or correct for, measurement error in a continuous exposure in nutritional epidemiology

Derrick A. Bennett, Denise Landry, Julian Little, Cosetta Minelli

Open Access Research article

Predicting the multi-domain progression of Parkinson’s disease: a Bayesian multivariate generalized linear mixed-effect model

Ming Wang, Zheng Li, Eun Young Lee, Mechelle M. Lewis, Lijun Zhang, Nicholas W. Sterling, Daymond Wagner, Paul Eslinger, Guangwei Du, Xuemei Huang

Open Access Research Article

Item response models for the longitudinal analysis of health-related quality of life in cancer clinical trials

Antoine Barbieri, Jean Peyhardi, Thierry Conroy, Sophie Gourgou, Christian Lavergne, Caroline Mollevi

Open Access Research article

Recruiting former melanoma patients via hospitals in comparison to office-based dermatologists in a register-based cohort study that required indirect contact

S. R. Zeissig, V. Weyer-Elberich, K. Emrich, H. Binder, S. Fischbeck, B. H. Imruck, P. Friedrich-Mai, M. E. Beutel, M. Blettner

Open Access Research article

Is the information of systematic reviews published in nursing journals up-to-date? a cross-sectional study

Wilson W. S. Tam, Kenneth K. H. Lo, Parames Khalechelvam, Joey Seah, Shawn Y. S. Goh

Open Access Research article

Frequency of data extraction errors and methods to increase data extraction quality: a methodological review

Tim Mathes, Pauline Klaßen, Dawid Pieper

Open Access Research article

Mobile electronic versus paper case report forms in clinical trials: a randomized controlled trial

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