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Zeitschrift

BMC Medicine

BMC Medicine 1/2013

Ausgabe 1/2013

Inhaltsverzeichnis ( 263 Artikel )

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Video Q&A: Excess body weight and cancer

Rudolf Kaaks

01.12.2013 | Guideline | Ausgabe 1/2013 Open Access

RAMESES publication standards: meta-narrative reviews

Geoff Wong, Trish Greenhalgh, Gill Westhorp, Jeanette Buckingham, Ray Pawson

01.12.2013 | Guideline | Ausgabe 1/2013 Open Access

RAMESES publication standards: realist syntheses

Geoff Wong, Trish Greenhalgh, Gill Westhorp, Jeanette Buckingham, Ray Pawson

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Plasminogen activator inhibitor-1 4G/5G polymorphism and retinopathy risk in type 2 diabetes: a meta-analysis

Tengyue Zhang, Chong Pang, Ningdong Li, Elaine Zhou, Kanxing Zhao

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases

Michela Flego, Alessandro Ascione, Maurizio Cianfriglia, Stefano Vella

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Support of personalized medicine through risk-stratified treatment recommendations - an environmental scan of clinical practice guidelines

Tsung Yu, Daniela Vollenweider, Ravi Varadhan, Tianjing Li, Cynthia Boyd, Milo A Puhan

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

How well do clinical prediction rules perform in identifying serious infections in acutely ill children across an international network of ambulatory care datasets?

Jan Y Verbakel, Ann Van den Bruel, Matthew Thompson, Richard Stevens, Bert Aertgeerts, Rianne Oostenbrink, Henriette A Moll, Marjolein Y Berger, Monica Lakhanpaul, David Mant, Frank Buntinx, the European Research Network on Recognising Serious Infection (ERNIE)

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Recent advances in the diagnosis and treatment of bladder cancer

Grace Cheung, Arun Sahai, Michele Billia, Prokar Dasgupta, Muhammad S Khan

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?

Michel de Lorgeril, Patricia Salen, Pascal Defaye, Mikael Rabaeus

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

Genetics of scleroderma: implications for personalized medicine?

Shervin Assassi, Timothy RDJ Radstake, Maureen D Mayes, Javier Martin

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

The young osteoarthritic knee: dilemmas in management

Paul M Sutton, Edward S Holloway

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Collectives of diagnostic biomarkers identify high-risk subpopulations of hematuria patients: exploiting heterogeneity in large-scale biomarker data

Frank Emmert-Streib, Funso Abogunrin, Ricardo de Matos Simoes, Brian Duggan, Mark W Ruddock, Cherith N Reid, Owen Roddy, Lisa White, Hugh F O'Kane, Declan O'Rourke, Neil H Anderson, Thiagarajan Nambirajan, Kate E Williamson

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Diet, a new target to prevent depression?

Almudena Sanchez-Villegas, Miguel A Martínez-González

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C

María A Jiménez-Sousa, Amanda Fernández-Rodríguez, María Guzmán-Fulgencio, Mónica García-Álvarez, Salvador Resino

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

Bariatric surgery: the challenges with candidate selection, individualizing treatment and clinical outcomes

KJ Neff, T Olbers, CW le Roux

01.12.2013 | Correspondence | Ausgabe 1/2013 Open Access

Economic analyses to support decisions about HPV vaccination in low- and middle-income countries: a consensus report and guide for analysts

Mark Jit, Carol Levin, Marc Brisson, Ann Levin, Stephen Resch, Johannes Berkhof, Jane Kim, Raymond Hutubessy

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

Epigenetic mechanisms in migraine: a promising avenue?

Else Eising, Nicole A Datson, Arn MJM van den Maagdenberg, Michel D Ferrari

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Paternal obesity is associated with IGF2hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

Adelheid Soubry, Joellen M Schildkraut, Amy Murtha, Frances Wang, Zhiqing Huang, Autumn Bernal, Joanne Kurtzberg, Randy L Jirtle, Susan K Murphy, Cathrine Hoyo

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Fat dads must not be blamed for their children's health problems

Gudrun E Moore, Philip Stanier

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Multigenerational epigenetic effects of nicotine on lung function

Frances M Leslie

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Smoking and HIV: time for a change?

Nicola Petrosillo, Stefania Cicalini

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition

Sabine Rohrmann, Kim Overvad, H Bas Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie, Paula Jakszyn, María-José Sánchez, José M Huerta, M Luisa Redondo, Aurelio Barricarte, Pilar Amiano, Isabel Drake, Emily Sonestedt, Göran Hallmans, Ingegerd Johansson, Veronika Fedirko, Isabelle Romieux, Pietro Ferrari, Teresa Norat, Anne C Vergnaud, Elio Riboli, Jakob Linseisen

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A bibliometric analysis of childhood immunization research productivity in Africa since the onset of the Expanded Program on Immunization in 1974

Charles S Wiysonge, Olalekan A Uthman, Peter M Ndumbe, Gregory D Hussey

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Causes of death after fluid bolus resuscitation: new insights from FEAST

John Myburgh, Simon Finfer

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Exploring mechanisms of excess mortality with early fluid resuscitation: insightsfrom the FEAST trial

Kathryn Maitland, Elizabeth C George, Jennifer A Evans, Sarah Kiguli, Peter Olupot-Olupot, Samuel O Akech, Robert O Opoka, Charles Engoru, Richard Nyeko, George Mtove, Hugh Reyburn, Bernadette Brent, Julius Nteziyaremye, Ayub Mpoya, Natalie Prevatt, Cornelius M Dambisya, Daniel Semakula, Ahmed Ddungu, Vicent Okuuny, Ronald Wokulira, Molline Timbwa, Benedict Otii, Michael Levin, Jane Crawley, Abdel G Babiker, Diana M Gibb, for the FEAST trial group

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Ethical considerations in the globalization of medicine – an interview with James Giordano

James Giordano

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Q&A - Global challenges of epilepsy management - an interview with Gretchen Birbeck

Gretchen Birbeck

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Q&A - Economic analyses for vaccine introduction decisions in low- and middle- income countries

Raymond Hutubessy

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Triple P-Positive Parenting programs: the folly of basing social policy on underpowered flawed studies

James C Coyne, Linda Kwakkenbos

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Systematic review and meta-analysis: influence of smoking cessation on incidence of pneumonia in HIV

Preeti De, Amanda Farley, Nicola Lindson, Paul Aveyard

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs?

Vasco Crispim Romão, Helena Canhão, João Eurico Fonseca

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Actigraphy assessments of circadian sleep-wake cycles in the Vegetative and Minimally Conscious States

Damian Cruse, Aurore Thibaut, Athena Demertzi, Julia C Nantes, Marie-Aurélie Bruno, Olivia Gosseries, Audrey Vanhaudenhuyse, Tristan A Bekinschtein, Adrian M Owen, Steven Laureys

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Meta-narrative and realist reviews: guidance, rules, publication standards and quality appraisal

David Gough

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The global burden of neonatal hypothermia: systematic review of a major challenge for newborn survival

Karsten Lunze, David E Bloom, Dean T Jamison, Davidson H Hamer

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Genetic discrimination and life insurance: a systematic review of the evidence

Yann Joly, Ida Ngueng Feze, Jacques Simard

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Depression pathogenesis and treatment: what can we learn from blood mRNA expression?

Nilay Hepgul, Annamaria Cattaneo, Patricia A Zunszain, Carmine M Pariante

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction

Yiming Wang, Xingde Liu, Dongfeng Zhang, Jianhui Chen, Shuzheng Liu, Michael Berk

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Duration of lithium treatment is a risk factor for reduced glomerular function: a cross-sectional study

Alberto Bocchetta, Raffaella Ardau, Paolo Carta, Franca Ligas, Claudia Sardu, Antonello Pani, Maria Del Zompo

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Managing the risk of lithium-induced nephropathy in the long-term treatment of patients with recurrent affective disorders

Emanuel Severus, Michael Bauer

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

A practical method to target individuals for outbreak detection and control

Gerardo Chowell, Cécile Viboud

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Peri-operative interventions producing better functional outcomes and enhanced recovery following total hip and knee arthroplasty: an evidence-based review

Mazin S Ibrahim, Muhammad A Khan, Ikram Nizam, Fares S Haddad

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Promoting networks between evidence-based medicine and values-based medicine in continuing medical education

Myriam M Altamirano-Bustamante, Nelly F Altamirano-Bustamante, Alberto Lifshitz, Ignacio Mora-Magaña, Adalberto de Hoyos, María Teresa Ávila-Osorio, Silvia Quintana-Vargas, Jorge A Aguirre, Jorge Méndez, Chiharu Murata, Rodrigo Nava-Diosdado, Oscar Martínez-González, Elisa Calleja, Raúl Vargas, Juan Manuel Mejía-Arangure, Araceli Cortez-Domínguez, Fernand Vedrenne-Gutiérrez, Perla Sueiras, Juan Garduño, Sergio Islas-Andrade, Fabio Salamanca, Jesús Kumate-Rodríguez, Alejandro Reyes-Fuentes

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study

Verena Sengpiel, Elisabeth Elind, Jonas Bacelis, Staffan Nilsson, Jakob Grove, Ronny Myhre, Margaretha Haugen, Helle Margrete Meltzer, Jan Alexander, Bo Jacobsson, Anne-Lise Brantsæter

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial

Clifford J Bailey, Jorge L Gross, Delphine Hennicken, Nayyar Iqbal, Traci A Mansfield, James F List

01.12.2013 | Guideline | Ausgabe 1/2013 Open Access

Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement

Don Husereau, Michael Drummond, Stavros Petrou, Chris Carswell, David Moher, Dan Greenberg, Federico Augustovski, Andrew H Briggs, Josephine Mauskopf, Elizabeth Loder

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A low-cost method to assess the epidemiological importance of individuals in controlling infectious disease outbreaks

Timo Smieszek, Marcel Salathé

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Biologic therapy for autoimmune diseases: an update

Ziv Rosman, Yehuda Shoenfeld, Gisele Zandman-Goddard

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The thrombophilic network of autoantibodies in celiac disease

Aaron Lerner, Nancy Agmon-Levin, Yinon Shapira, Boris Gilburd, Sandra Reuter, Idit Lavi, Yehuda Shoenfeld

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus

Shaye Kivity, Aviva Katzav, Maria Teresa Arango, Moran Landau-Rabi, Yaron Zafrir, Nancy Agmon-Levin, Miri Blank, Juan-Manuel Anaya, Edna Mozes, Joab Chapman, Yehuda Shoenfeld

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Discoveries in the pathophysiology of neuropsychiatric lupus erythematosus: consequences for therapy

Takahisa Gono, Yasushi Kawaguchi, Hisashi Yamanaka

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Coagulopathy triggered autoimmunity: experimental antiphospholipid syndrome in factor V Leiden mice

Aviva Katzav, Nikolaos C Grigoriadis, Tania Ebert, Olga Touloumi, Miri Blank, Chaim G Pick, Yehuda Shoenfeld, Joab Chapman

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Novel aspects of Sjögren’s syndrome in 2012

Angela Tincani, Laura Andreoli, Ilaria Cavazzana, Andrea Doria, Marta Favero, Maria-Giulia Fenini, Franco Franceschini, Andrea Lojacono, Giuseppe Nascimbeni, Amerigo Santoro, Francesco Semeraro, Paola Toniati, Yehuda Shoenfeld

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Age-related autoimmunity

Zahava Vadasz, Tharwat Haj, Aharon Kessel, Elias Toubi

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Renal involvement in autoimmune connective tissue diseases

Andreas Kronbichler, Gert Mayer

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Phosphodiesterase 4-targeted treatments for autoimmune diseases

Neal Kumar, Ari M Goldminz, Noori Kim, Alice B Gottlieb

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Associations between selected immune-mediated diseases and tuberculosis: record-linkage studies

Sreeram V Ramagopalan, Raph Goldacre, Andrew Skingsley, Chris Conlon, Michael J Goldacre

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile

Diana Carmona-Fernandes, Maria José Santos, Helena Canhão, João Eurico Fonseca

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Slow CCL2-dependent translocation of biopersistent particles from muscle to brain

Zakir Khan, Christophe Combadière, François-Jérôme Authier, Valérie Itier, François Lux, Christopher Exley, Meriem Mahrouf-Yorgov, Xavier Decrouy, Philippe Moretto, Olivier Tillement, Romain K Gherardi, Josette Cadusseau

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Requirements for innate immune pathways in environmentally induced autoimmunity

Kenneth Michael Pollard, Dwight H Kono

01.12.2013 | Technical advance | Ausgabe 1/2013 Open Access

Quantifiable diagnosis of muscular dystrophies and neurogenic atrophies through network analysis

Aurora Sáez, Eloy Rivas, Adoración Montero-Sánchez, Carmen Paradas, Begoña Acha, Alberto Pascual, Carmen Serrano, Luis M Escudero

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Hypersomnia and depressive symptoms: methodological and clinical aspects

Yves Dauvilliers, Régis Lopez, Maurice Ohayon, Sophie Bayard

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Impact of diuretic therapy-associated electrolyte disorders present on admission to the emergency department: a cross-sectional analysis

Spyridon Arampatzis, Georg-Christian Funk, Alexander Benedikt Leichtle, Georg-Martin Fiedler, Christoph Schwarz, Heinz Zimmermann, Aristomenis Konstantinos Exadaktylos, Gregor Lindner

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Reporting of analyses from randomized controlled trials with multiple arms: a systematic review

Gabriel Baron, Elodie Perrodeau, Isabelle Boutron, Philippe Ravaud

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Novel approaches to minimize ventilator-induced lung injury

Eddy Fan, Jesus Villar, Arthur S Slutsky

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

High-end normal adrenocorticotropic hormone and cortisol levels are associated with specific cardiovascular risk factors in pediatric obesity: a cross-sectional study

Flavia Prodam, Roberta Ricotti, Valentina Agarla, Silvia Parlamento, Giulia Genoni, Caterina Balossini, Gillian Elisabeth Walker, Gianluca Aimaretti, Gianni Bona, Simonetta Bellone

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Shifting from glucose diagnosis to the new HbA1c diagnosis reduces the capability of the Finnish Diabetes Risk Score (FINDRISC) to screen for glucose abnormalities within a real-life primary healthcare preventive strategy

Bernardo Costa, Francisco Barrio, Josep L Piñol, Joan J Cabré, Xavier Mundet, Ramon Sagarra, Jordi Salas-Salvadó, Oriol Solà-Morales, the DE-PLAN-CAT/PREDICE Research Group

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

Mora Murri, Isabel Leiva, Juan Miguel Gomez-Zumaquero, Francisco J Tinahones, Fernando Cardona, Federico Soriguer, María Isabel Queipo-Ortuño

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Combined impact of traditional and non-traditional health behaviors on mortality: a national prospective cohort study in Spanish older adults

David Martínez-Gómez, Pilar Guallar-Castillón, Luz M León-Muñoz, Esther López-García, Fernando Rodríguez-Artalejo

01.12.2013 | Guideline | Ausgabe 1/2013 Open Access

Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults: an evidence and consensus-based update

Johan Undén, Tor Ingebrigtsen, Bertil Romner, the Scandinavian Neurotrauma Committee (SNC)

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

New guidelines for the initial management of head injury

Carolyn M Benson, G Bryan Young

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Maternal plasma sequencing: a powerful tool towards fetal whole genome recovery

Elisavet A Papageorgiou, Philippos C Patsalis

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials

C Mary Schooling, Shiu Lun Au Yeung, Guy Freeman, Benjamin J Cowling

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Do statins lower testosterone and does it matter?

Allan D Sniderman, George Thanassoulis

01.12.2013 | Editorial | Ausgabe 1/2013 Open Access

Medicine for global health: can “simple interventions” improve the worldwide burden of disease?

Gretchen Birbeck

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Evidence-based medicine and values-based medicine: partners in clinical education as well as in clinical practice

Ed Peile

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Tackling overweight and obesity: does the public health message match the science?

Katherine Hafekost, David Lawrence, Francis Mitrou, Therese A O'Sullivan, Stephen R Zubrick

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Impact of geriatric consultation teams on clinical outcome in acute hospitals: a systematic review and meta-analysis

Mieke Deschodt, Johan Flamaing, Patrick Haentjens, Steven Boonen, Koen Milisen

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Fascin-1 is a novel biomarker of aggressiveness in some carcinomas

Vathany Kulasingam, Eleftherios P Diamandis

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity

Jurriaan M Peters, Maxime Taquet, Clemente Vega, Shafali S Jeste, Iván Sánchez Fernández, Jacqueline Tan, Charles A Nelson III, Mustafa Sahin, Simon K Warfield

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis

Vanessa Y Tan, Sarah J Lewis, Josephine C Adams, Richard M Martin

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Worse prognosis of KRASc.35 G > A mutant metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx)

Gemma Bruera, Katia Cannita, Daniela Di Giacomo, Aude Lamy, Thierry Frébourg, Jean Christophe Sabourin, Mario Tosi, Edoardo Alesse, Corrado Ficorella, Enrico Ricevuto

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Summative assessments are more powerful drivers of student learning than resource intensive teaching formats

Tobias Raupach, Jamie Brown, Sven Anders, Gerd Hasenfuss, Sigrid Harendza

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Evaluating complex interventions in End of Life Care: the MORECare Statement on good practice generated by a synthesis of transparent expert consultations and systematic reviews

Irene J Higginson, Catherine J Evans, Gunn Grande, Nancy Preston, Myfanwy Morgan, Paul McCrone, Penney Lewis, Peter Fayers, Richard Harding, Matthew Hotopf, Scott A Murray, Hamid Benalia, Marjolein Gysels, Morag Farquhar, Chris Todd

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Manipulating the sleep-wake cycle and circadian rhythms to improve clinical management of major depression

Ian B Hickie, Sharon L Naismith, Rébecca Robillard, Elizabeth M Scott, Daniel F Hermens

01.12.2013 | Editorial | Ausgabe 1/2013 Open Access

Novel pebbles in the mosaic of autoimmunity

Carlo Perricone, Nancy Agmon-Levin, Yehuda Shoenfeld

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Use of illicit and prescription drugs for cognitive or mood enhancement among surgeons

Andreas G Franke, Christiana Bagusat, Pavel Dietz, Isabell Hoffmann, Perikles Simon, Rolf Ulrich, Klaus Lieb

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

‘You can’t just hit a button’: an ethnographic study of strategies to repurpose data from advanced clinical information systems for clinical process improvement

Cecily Morrison, Matthew Jones, Rachel Jones, Alain Vuylsteke

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

Advances in bladder cancer imaging

Shaista Hafeez, Robert Huddart

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity

Yi-Chiung Hsu, Hsuan-Yu Chen, Shinsheng Yuan, Sung-Liang Yu, Chia-Hung Lin, Guani Wu, Pan-Chyr Yang, Ker-Chau Li

01.12.2013 | Correspondence | Ausgabe 1/2013 Open Access

Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research

Shevin T Jacob, Matthew Lim, Patrick Banura, Satish Bhagwanjee, Julian Bion, Allen C Cheng, Hillary Cohen, Jeremy Farrar, Sandy Gove, Philip Hopewell, Christopher C Moore, Cathy Roth, T Eoin West

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Evo-devo of human adolescence: beyond disease models of early puberty

Ze'ev Hochberg, Jay Belsky

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Effects of breastfeeding on body composition and maturational tempo in the rat

Yonatan Crispel, Oren Katz, Dafna Ben-Yosef, Ze'ev Hochberg

01.12.2013 | Review | Ausgabe 1/2013 Open Access

New perspectives on evolutionary medicine: the relevance of microevolution for human health and disease

Frank Jakobus Rühli, Maciej Henneberg

01.12.2013 | Editorial | Ausgabe 1/2013 Open Access

Evolutionary medicine – the quest for a better understanding of health, disease and prevention

Martin Brüne, Ze’ev Hochberg

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Income and patient-reported outcomes (PROs) after primary total knee arthroplasty

Jasvinder A Singh, David G Lewallen

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Video Q&A: what is ASIA? An interview with Yehuda Shoenfeld

Yehuda Shoenfeld

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Caregivers’ understanding of dementia predicts patients’ comfort at death: a prospective observational study

Jenny T van der Steen, Bregje D Onwuteaka-Philipsen, Dirk L Knol, Miel W Ribbe, Luc Deliens

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials

Lin Xu, Guy Freeman, Benjamin J Cowling, C Mary Schooling

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors

Su-Jin Park, Birgit Sawitzki, Lan Kluwe, Victor F Mautner, Nikola Holtkamp, Andreas Kurtz

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Physical comorbidities in men with mood and anxiety disorders: a population-based study

Livia Sanna, Amanda L Stuart, Julie A Pasco, Mark A Kotowicz, Michael Berk, Paolo Girardi, Sharon L Brennan, Lana J Williams

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Developmental heterochrony and the evolution of autistic perception, cognition and behavior

Bernard Crespi

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Drug eluting balloons for de novocoronary lesions – a systematic review and meta-analysis

Georg M Fröhlich, Alexandra J Lansky, Dennis T Ko, Olga Archangelidi, Rodney De Palma, Adam Timmis, Pascal Meier

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Depression, antidepressant medications, and risk of Clostridium difficileinfection

Mary AM Rogers, M Todd Greene, Vincent B Young, Sanjay Saint, Kenneth M Langa, John Y Kao, David M Aronoff

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study

Tao Xu, Christina Holzapfel, Xiao Dong, Erik Bader, Zhonghao Yu, Cornelia Prehn, Katrin Perstorfer, Marta Jaremek, Werner Roemisch-Margl, Wolfgang Rathmann, Yixue Li, H -Erich Wichmann, Henri Wallaschofski, Karl H Ladwig, Fabian Theis, Karsten Suhre, Jerzy Adamski, Thomas Illig, Annette Peters, Rui Wang-Sattler

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine

Crystal D Hayes, Debleena Dey, Juan Pablo Palavicini, Hongjie Wang, Kshitij A Patkar, Dimitriy Minond, Adel Nefzi, Madepalli K Lakshmana

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Potential repurposing of oncology drugs for the treatment of Alzheimer's disease

Wataru Araki

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Calcium-deficiency assessment and biomarker identification by an integrated urinary metabonomics analysis

Maoqing Wang, Xue Yang, Fan Wang, Ran Li, Hua Ning, Lixin Na, Yifan Huang, Yue Song, Liyan Liu, Hongzhi Pan, Qiuju Zhang, Lijun Fan, Ying Li, Changhao Sun

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Clinical classification in mental health at the cross-roads: which direction next?

Ian B Hickie, Jan Scott, Daniel F Hermens, Elizabeth M Scott, Sharon L Naismith, Adam J Guastella, Nick Glozier, Patrick D McGorry

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

Bruce N Cuthbert, Thomas R Insel

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Informing DSM-5: biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia

Victoria E Cosgrove, Trisha Suppes

01.12.2013 | Editorial | Ausgabe 1/2013 Open Access

The DSM-5: Hyperbole, Hope or Hypothesis?

Michael Berk

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

How do autoimmune diseases cluster in families? A systematic review and meta-analysis

Jorge Cárdenas-Roldán, Adriana Rojas-Villarraga, Juan-Manuel Anaya

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The genomic landscape of chronic lymphocytic leukemia: clinical implications

Víctor Quesada, Andrew J Ramsay, David Rodríguez, Xose S Puente, Elías Campo, Carlos López-Otín

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Immunity, atherosclerosis and cardiovascular disease

Johan Frostegård

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Depression as a risk factor for adverse outcomes in coronary heart disease

Kenneth E Freedland, Robert M Carney

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Patient advocacy and DSM-5

Dan J Stein, Katharine A Phillips

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Body mass index and incident coronary heart disease in women: a population-based prospective study

Dexter Canoy, Benjamin J Cairns, Angela Balkwill, F Lucy Wright, Jane Green, Gillian Reeves, Valerie Beral, the Million Women Study Collaborators

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile

Brenda WJH Penninx, Yuri Milaneschi, Femke Lamers, Nicole Vogelzangs

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Depression as a non-causal variable risk marker in coronary heart disease

Anna Meijer, Marij Zuidersma, Peter de Jonge

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Targeted rotavirus vaccination of high-risk infants; a low cost and highly cost-effective alternative to universal vaccination

Patricia Bruijning-Verhagen, Marie-Josée J Mangen, Mariet Felderhof, Nico G Hartwig, Marlies van Houten, Léon Winkel, Wouter J de Waal, Marc JM Bonten

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model

Carina A Bäuerlein, Simone S Riedel, Jeanette Baker, Christian Brede, Ana-Laura Jordán Garrote, Martin Chopra, Miriam Ritz, Georg F Beilhack, Stephan Schulz, Robert Zeiser, Paul G Schlegel, Hermann Einsele, Robert S Negrin, Andreas Beilhack

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Novel therapeutic agents in clinical development for systemic lupus erythematosus

Natasha Jordan, Pamela MK Lutalo, David P D’Cruz

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Characteristics, changes and influence of body composition during a 4486 km transcontinental ultramarathon: results from the Transeurope Footrace mobile whole body MRI-project

Uwe HW Schütz, Christian Billich, Kathrin König, Christian Würslin, Heike Wiedelbach, Hans-Jürgen Brambs, Jürgen Machann

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Personalized medicine in psychiatry: problems and promises

Uzoezi Ozomaro, Claes Wahlestedt, Charles B Nemeroff

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Cost effectiveness of patient education for the prevention of falls in hospital: economic evaluation from a randomized controlled trial

Terry P Haines, Anne-Marie Hill, Keith D Hill, Sandra G Brauer, Tammy Hoffmann, Christopher Etherton-Beer, Steven M McPhail

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Neuromuscular electrical stimulation for preventing skeletal-muscle weakness and wasting in critically ill patients: a systematic review

Nicola A Maffiuletti, Marc Roig, Eleftherios Karatzanos, Serafim Nanas

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Venous hemodynamics in neurological disorders: an analytical review with hydrodynamic analysis

Clive B Beggs

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivoeffects on migration capacity and tumor growth

Carolina Belmar-Lopez, Gracia Mendoza, Daniel Oberg, Jerome Burnet, Carlos Simon, Irene Cervello, Maite Iglesias, Juan Carlos Ramirez, Pilar Lopez-Larrubia, Miguel Quintanilla, Pilar Martin-Duque

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Is a combination of varenicline and nicotine patch more effective in helping smokers quit than varenicline alone? A randomised controlled trial

Peter Hajek, Katie Myers Smith, Al-Rehan Dhanji, Hayden McRobbie

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Processing of meats and cardiovascular risk: time to focus on preservatives

Renata Micha, Georgios Michas, Martin Lajous, Dariush Mozaffarian

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Tobacco smoking and depression: time to move on to a new research paradigm in medicine?

Peter de Jonge, Elisabeth Henriette Bos

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Are behavioral interventions effective in increasing physical activity at 12 to 36 months in adults aged 55 to 70 years? a systematic review and meta-analysis

Nicola Hobbs, Alan Godfrey, Jose Lara, Linda Errington, Thomas D Meyer, Lynn Rochester, Martin White, John C Mathers, Falko F Sniehotta

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Why do hypertensive patients of African ancestry respond better to calciumblockers and diuretics than to ACE inhibitors and β-adrenergic blockers? Asystematic review

Lizzy M Brewster, Yackoob K Seedat

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Ipsilateral lower extremity joint involvement increases the risk of poor pain and function outcomes after hip or knee arthroplasty

Jasvinder A Singh, David G Lewallen

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Sodium vanadate combined with l-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy

Huei-Chun Liu, Chen-Hung Ting, Hsin-Lan Wen, Li-Kai Tsai, Hsiu-Mei Hsieh-Li, Hung Li, Sue Lin-Chao

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

When to start antiretroviral therapy: as soon as possible

Ricardo A Franco, Michael S Saag

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

When to start antiretroviral therapy: the need for an evidence base during early HIV infection

Jens D Lundgren, Abdel G Babiker, Fred M Gordin, Álvaro H Borges, James D Neaton

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

Origins of increased airway smooth muscle mass in asthma

Rachid Berair, Ruth Saunders, Christopher E Brightling

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The collateral circulation of the heart

Pascal Meier, Stephan H Schirmer, Alexandra J Lansky, Adam Timmis, Bertram Pitt, Christian Seiler

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Video Q&A: molecular profiling of breast cancer

Carlos Caldas

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

Genetic heterogeneity in breast cancer: the road to personalized medicine?

Richard D Baird, Carlos Caldas

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells

Georg Siegel, Torsten Kluba, Ursula Hermanutz-Klein, Karen Bieback, Hinnak Northoff, Richard Schäfer

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

Video Q&A: Rapid urine LAM test for HIV-associated TB - potential to reduce deaths? An interview with Stephen Lawn

Stephen D Lawn

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Factors associated with patient, and diagnostic delays in Chinese TB patients: a systematic review and meta-analysis

Ying Li, John Ehiri, Shenglan Tang, Daikun Li, Yongqiao Bian, Hui Lin, Caitlin Marshall, Jia Cao

01.12.2013 | Review | Ausgabe 1/2013 Open Access

New insights into mechanisms behind miscarriage

Elisabeth Clare Larsen, Ole Bjarne Christiansen, Astrid Marie Kolte, Nick Macklon

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The role of noninvasive and invasive diagnostic imaging techniques for detection of extra-cranial venous system anomalies and developmental variants

Kresimir Dolic, Adnan H Siddiqui, Yuval Karmon, Karen Marr, Robert Zivadinov

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The differential role of androgens in early human sex development

Olaf Hiort

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

Andrea C Tricco, Ayman Chit, Charlene Soobiah, David Hallett, Genevieve Meier, Maggie H Chen, Mariam Tashkandi, Chris T Bauch, Mark Loeb

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Is network meta-analysis as valid as standard pairwise meta-analysis? It all depends on the distribution of effect modifiers

Jeroen P Jansen, Huseyin Naci

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

Adam E Handel, Geir K Sandve, Giulio Disanto, Antonio J Berlanga-Taylor, Giuseppe Gallone, Heather Hanwell, Finn Drabløs, Gavin Giovannoni, George C Ebers, Sreeram V Ramagopalan

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Personalizing guidelines for diabetes management: twilight or dawn of the expert?

Stavroula A Paschou, Richard David Leslie

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial

Marta Guasch-Ferré, Mònica Bulló, Miguel Ángel Martínez-González, Emilio Ros, Dolores Corella, Ramon Estruch, Montserrat Fitó, Fernando Arós, Julia Wärnberg, Miquel Fiol, José Lapetra, Ernest Vinyoles, Rosa Maria Lamuela-Raventós, Lluís Serra-Majem, Xavier Pintó, Valentina Ruiz-Gutiérrez, Josep Basora, Jordi Salas-Salvadó

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Should we go nuts about nuts?

Sabine Rohrmann, David Faeh

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial

Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Huimin Zhou, Zhaohui Yin, Yana Chen, Ye Zhang, Shanfeng Wang, Jie Shen, Hatim Thaker, Summit Jain, Yunxiang Li, Yalin Diao, Yingjian Chen, Xiaoming Sun, Mary Beth Fisk, Heng Li

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Evaluation of the acceptability and usefulness of an information website for caregivers of people with bipolar disorder

Lesley Berk, Michael Berk, Seetal Dodd, Claire Kelly, Stefan Cvetkovski, Anthony Francis Jorm

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Understanding breast cancer stem cell heterogeneity: time to move on to a new research paradigm

Ferdinando Mannello

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Special considerations in prognostic research in cancer involving genetic polymorphisms

Sevtap Savas, Geoffrey Liu, Wei Xu

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Diabetic retinopathy in sub-Saharan Africa: meeting the challenges of an emerging epidemic

Philip I Burgess, Gerald Msukwa, Nicholas AV Beare

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Hospital admissions for vitamin D related conditions and subsequent immune-mediated disease: record-linkage studies

Sreeram V Ramagopalan, Raph Goldacre, Giulio Disanto, Gavin Giovannoni, Michael J Goldacre

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Chronic cerebrospinal venous insufficiency is not associated with cognitive impairment in multiple sclerosis

Ralph HB Benedict, Bianca Weinstock-Guttmam, Karen Marr, Vesela Valnarov, Cheryl Kennedy, Ellen Carl, Christina Brooks, David Hojnacki, Robert Zivadinov

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Comparative assessment of absolute cardiovascular disease risk characterization from non-laboratory-based risk assessment in South African populations

Thomas A Gaziano, Ankur Pandya, Krisela Steyn, Naomi Levitt, Willie Mollentze, Gina Joubert, Corinna M Walsh, Ayesha A Motala, Annamarie Kruger, Aletta E Schutte, Datshana P Naidoo, Dorcas R Prakaschandra, Ria Laubscher

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Safety of TNF-α inhibitors during IBD pregnancy: a systematic review

Ole Haagen Nielsen, Edward V Loftus Jr, Tine Jess

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

Amarjargal Dashdorj, Jyothi KR, Sangbin Lim, Ara Jo, Minh Nam Nguyen, Joohun Ha, Kyung-Sik Yoon, Hyo Jong Kim, Jae-Hoon Park, Michael P Murphy, Sung Soo Kim

01.12.2013 | Review | Ausgabe 1/2013 Open Access

A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior

Gerwyn Morris, George Anderson, Piotr Galecki, Michael Berk, Michael Maes

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness

Michael Berk, Olivia Dean, Hemmo Drexhage, John J McNeil, Steven Moylan, Adrienne O'Neil, Christopher G Davey, Livia Sanna, Michael Maes

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era

John F Brothers, Kahkeshan Hijazi, Celine Mascaux, Randa A El-Zein, Margaret R Spitz, Avrum Spira

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Sleeping well

Mithu Sen, G Bryan Young

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Geriatric consultation services-are wards more effective than teams?

Ian D Cameron, Susan Kurrle

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Neural connectivity abnormalities in autism: Insights from the Tuberous Sclerosis model

Charlotte Tye, Patrick Bolton

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial

Ian D Cameron, Nicola Fairhall, Colleen Langron, Keri Lockwood, Noeline Monaghan, Christina Aggar, Catherine Sherrington, Stephen R Lord, Susan E Kurrle

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Drug-induced dyskinesia in Parkinson's disease. Should success in clinical management be a function of improvement of motor repertoire rather than amplitude of dyskinesia?

Jean-François Daneault, Benoit Carignan, Abbas F Sadikot, Michel Panisset, Christian Duval

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Serum concentrations of 25-hydroxyvitamin D and immunoglobulins in an older Swiss cohort: results of the Senior Labor Study

Benjamin Sakem, Cristina Nock, Zeno Stanga, Pedro Medina, Urs E Nydegger, Martin Risch, Lorenz Risch

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The sweet and sour of serological glycoprotein tumor biomarker quantification

Uros Kuzmanov, Hari Kosanam, Eleftherios P Diamandis

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

George M Warimwe, Helen A Fletcher, Ally Olotu, Selidji T Agnandji, Adrian VS Hill, Kevin Marsh, Philip Bejon

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways

Robert P Anderson, Margaret J Henry, Roberta Taylor, Emma L Duncan, Patrick Danoy, Marylia J Costa, Kathryn Addison, Jason A Tye-Din, Mark A Kotowicz, Ross E Knight, Wendy Pollock, Geoffrey C Nicholson, Ban-Hock Toh, Matthew A Brown, Julie A Pasco

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Plasma procalcitonin is associated with all-cause and cancer mortality in apparently healthy men: a prospective population-based study

Ovidiu S Cotoi, Jonas Manjer, Bo Hedblad, Gunnar Engström, Olle Melander, Alexandru Schiopu

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Systematic review of clinical practice guidelines in the diagnosis and management of thyroid nodules and cancer

Tsai-Wei Huang, Jun-Hung Lai, Mei-Yi Wu, Shiah-Lian Chen, Chih-Hsiung Wu, Ka-Wai Tam

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Associations between smoking, components of metabolic syndrome and lipoprotein particle size

Sandra N Slagter, Jana V van Vliet-Ostaptchouk, Judith M Vonk, H Marike Boezen, Robin PF Dullaart, Anneke C Muller Kobold, Edith J Feskens, André P van Beek, Melanie M van derKlauw, Bruce HR Wolffenbuttel

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III

Xinqing Deng, Yiqing Song, JoAnn E Manson, Lisa B Signorello, Shumin M Zhang, Martha J Shrubsole, Reid M Ness, Douglas L Seidner, Qi Dai

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A method for inferring medical diagnoses from patient similarities

Assaf Gottlieb, Gideon Y Stein, Eytan Ruppin, Russ B Altman, Roded Sharan

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Diagnostic heterogeneity in psychiatry: towards an empirical solution

Klaas J Wardenaar, Peter de Jonge

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Mediterranean dietary pattern and depression: the PREDIMED randomized trial

Almudena Sánchez-Villegas, Miguel Angel Martínez-González, Ramón Estruch, Jordi Salas-Salvadó, Dolores Corella, Maria Isabel Covas, Fernando Arós, Dora Romaguera, Enrique Gómez-Gracia, José Lapetra, Xavier Pintó, Jose Alfredo Martínez, Rosa María Lamuela-Raventós, Emilio Ros, Alfredo Gea, Julia Wärnberg, Lluis Serra-Majem

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

So depression is an inflammatory disease, but where does the inflammation come from?

Michael Berk, Lana J Williams, Felice N Jacka, Adrienne O’Neil, Julie A Pasco, Steven Moylan, Nicholas B Allen, Amanda L Stuart, Amie C Hayley, Michelle L Byrne, Michael Maes

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Pharmacological treatments in ARDS; a state-of-the-art update

Andrew James Boyle, Rob Mac Sweeney, Daniel Francis McAuley

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial

Estefania Toledo, Frank B Hu, Ramon Estruch, Pilar Buil-Cosiales, Dolores Corella, Jordi Salas-Salvadó, M Isabel Covas, Fernando Arós, Enrique Gómez-Gracia, Miquel Fiol, Jose Lapetra, Luis Serra-Majem, Xavier Pinto, Rosa M Lamuela-Raventós, Guillermo Saez, Mònica Bulló, Valentina Ruiz-Gutiérrez, Emilio Ros, José V Sorli, Miguel Angel Martinez-Gonzalez

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Perineal Assessment and Repair Longitudinal Study (PEARLS): a matched-pair cluster randomized trial

Khaled M K Ismail, Christine Kettle, Sue E Macdonald, Sue Tohill, Peter W Thomas, Debra Bick

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Hypnotics and mortality in an elderly general population: a 12-year prospective study

Isabelle Jaussent, Marie-Laure Ancelin, Claudine Berr, Karine Pérès, Jacqueline Scali, Alain Besset, Karen Ritchie, Yves Dauvilliers

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Patients with osteoarthritis and avascular necrosis have better functional outcomes and those with avascular necrosis worse pain outcomes compared to rheumatoid arthritis after primary hip arthroplasty: a cohort study

Jasvinder A Singh, David G Lewallen

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Development and evaluation of the feasibility and effects on staff, patients, and families of a new tool, the Psychosocial Assessment and Communication Evaluation (PACE), to improve communication and palliative care in intensive care and during clinical uncertainty

Irene J Higginson, Jonathan Koffman, Philip Hopkins, Wendy Prentice, Rachel Burman, Sara Leonard, Caroline Rumble, Jo Noble, Odette Dampier, William Bernal, Sue Hall, Myfanwy Morgan, Cathy Shipman

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Transmission potential of influenza A/H7N9, February to May 2013, China

Gerardo Chowell, Lone Simonsen, Sherry Towers, Mark A Miller, Cécile Viboud

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

A combined community- and facility-based approach to improve pregnancy outcomes in low-resource settings: a Global Network cluster randomized trial

Omrana Pasha, Elizabeth M McClure, Linda L Wright, Sarah Saleem, Shivaprasad S Goudar, Elwyn Chomba, Archana Patel, Fabian Esamai, Ana Garces, Fernando Althabe, Bhala Kodkany, Hillary Mabeya, Albert Manasyan, Waldemar A Carlo, Richard J Derman, Patricia L Hibberd, Edward K Liechty, Nancy Krebs, K Michael Hambidge, Pierre Buekens, Janet Moore, Alan H Jobe, Marion Koso-Thomas, Dennis D Wallace, Suzanne Stalls, Robert L Goldenberg

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Current drivers and geographic patterns of HIV in Lesotho: implications for treatment and prevention in Sub-Saharan Africa

Brian J Coburn, Justin T Okano, Sally Blower

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Which placebo to cure depression? A thought-provoking network meta-analysis

Florian Naudet, Bruno Millet, Philippe Charlier, Jean Michel Reymann, Anne Solène Maria, Bruno Falissard

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Physical activity and clustered cardiovascular disease risk factors in young children: a cross-sectional study (the IDEFICS study)

David Jiménez-Pavón, Kenn Konstabel, Patrick Bergman, Wolfgang Ahrens, Hermann Pohlabeln, Charalampos Hadjigeorgiou, Alfonso Siani, Licia Iacoviello, Dénes Molnár, Stefaan De Henauw, Yannis Pitsiladis, Luis A Moreno

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Insights into physical activity and cardiovascular disease risk in young children: IDEFICS study

Robert G McMurray

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The relationship of Asperger’s syndrome to autism: a preliminary EEG coherence study

Frank H Duffy, Aditi Shankardass, Gloria B McAnulty, Heidelise Als

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Personalizing health care: feasibility and future implications

Brian Godman, Alexander E Finlayson, Parneet K Cheema, Eva Zebedin-Brandl, Inaki Gutiérrez-Ibarluzea, Jan Jones, Rickard E Malmström, Elina Asola, Christoph Baumgärtel, Marion Bennie, Iain Bishop, Anna Bucsics, Stephen Campbell, Eduardo Diogene, Alessandra Ferrario, Jurij Fürst, Kristina Garuoliene, Miguel Gomes, Katharine Harris, Alan Haycox, Harald Herholz, Krystyna Hviding, Saira Jan, Marija Kalaba, Christina Kvalheim, Ott Laius, Sven-Ake Lööv, Kamila Malinowska, Andrew Martin, Laura McCullagh, Fredrik Nilsson, Ken Paterson, Ulrich Schwabe, Gisbert Selke, Catherine Sermet, Steven Simoens, Dominik Tomek, Vera Vlahovic-Palcevski, Luka Voncina, Magdalena Wladysiuk, Menno van Woerkom, Durhane Wong-Rieger, Corrine Zara, Raghib Ali, Lars L Gustafsson

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease

Jadwiga A Wedzicha, Simon E Brill, James P Allinson, Gavin C Donaldson

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Challenges and opportunities for oral pre-exposure prophylaxis in the prevention of HIV infection: where are we in Europe?

Jean-Michel Molina, Claire Pintado, Caroline Gatey, Diane Ponscarme, Pierre Charbonneau, Benedicte Loze, Willy Rozenbaum, Constance Delaugerre

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Additional Saturday rehabilitation improves functional independence and quality of life and reduces length of stay: a randomized controlled trial

Casey L Peiris, Nora Shields, Natasha K Brusco, Jennifer J Watts, Nicholas F Taylor

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Increasing the dose of acute rehabilitation: is there a benefit?

Ann M Parker, Robert K Lord, Dale M Needham

01.12.2013 | Forum | Ausgabe 1/2013 Open Access

DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions

Charles B Nemeroff, Daniel Weinberger, Michael Rutter, Harriet L MacMillan, Richard A Bryant, Simon Wessely, Dan J Stein, Carmine M Pariante, Florian Seemüller, Michael Berk, Gin S Malhi, Martin Preisig, Martin Brüne, Paul Lysaker

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

DSM-5 and ADHD – an interview with Eric Taylor

Eric Taylor

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Integrating multiple ‘omics’ analyses identifies serological protein biomarkers for preeclampsia

Linda Y Liu, Ting Yang, Jun Ji, Qiaojun Wen, Alexander A Morgan, Bo Jin, Gongxing Chen, Deirdre J Lyell, David K Stevenson, Xuefeng B Ling, Atul J Butte

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

The link between chronic periodontitis and COPD: a common role for the neutrophil?

Adam KH Usher, Robert A Stockley

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children – a prospective observational cohort study of 6,601 admissions

Signe Thiesen, Elizabeth J Conroy, Jennifer R Bellis, Louise E Bracken, Helena L Mannix, Kim A Bird, Jennifer C Duncan, Lynne Cresswell, Jamie J Kirkham, Matthew Peak, Paula R Williamson, Anthony J Nunn, Mark A Turner, Munir Pirmohamed, Rosalind L Smyth

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Improving global health governance to combat counterfeit medicines: a proposal for a UNODC-WHO-Interpol trilateral mechanism

Tim K Mackey, Bryan A Liang

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Managing HIV/hepatitis C co-infection in the era of direct acting antivirals

Jürgen K Rockstroh, Sanjay Bhagani

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The Academic Backbone: longitudinal continuities in educational achievement from secondary school and medical school to MRCP(UK) and the specialist register in UK medical students and doctors

IC McManus, Katherine Woolf, Jane Dacre, Elisabeth Paice, Chris Dewberry

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Construct-level predictive validity of educational attainment and intellectual aptitude tests in medical student selection: meta-regression of six UK longitudinal studies

IC McManus, Chris Dewberry, Sandra Nicholson, Jonathan S Dowell, Katherine Woolf, Henry WW Potts

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The UKCAT-12 study: educational attainment, aptitude test performance, demographic and socio-economic contextual factors as predictors of first year outcome in a cross-sectional collaborative study of 12 UK medical schools

I C McManus, Chris Dewberry, Sandra Nicholson, Jonathan S Dowell

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Selecting the right medical student

Sam Leinster

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Cognitive health begins at conception: addressing dementia as a lifelong and preventable condition

Jennifer H Barnett, Vladimir Hachinski, Andrew D Blackwell

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Admission prevention in COPD: non-pharmacological management

Eui-Sik Suh, Swapna Mandal, Nicholas Hart

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

What if HIV were unable to develop resistance against a new therapeutic agent?

Mark A Wainberg, Thibault Mesplède, Francois Raffi

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Do people with HIV infection have a normal life expectancy in the era of combination antiretroviral therapy?

Caroline A Sabin

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Effectiveness of Primary Care Triple P on child psychosocial problems in preventive child healthcare: a randomized controlled trial

Willem Spijkers, Daniëlle EMC Jansen, Sijmen A Reijneveld

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Containing the accidental laboratory escape of potential pandemic influenza viruses

Stefano Merler, Marco Ajelli, Laura Fumanelli, Alessandro Vespignani

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Who uses emergency departments inappropriately and when - a national cross-sectional study using a monitoring data system

Philip McHale, Sara Wood, Karen Hughes, Mark A Bellis, Ulf Demnitz, Sacha Wyke

01.12.2013 | Editorial | Ausgabe 1/2013 Open Access

Is there a link between the extracranial venous system and central nervous system pathology?

Robert Zivadinov

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Potential involvement of the extracranial venous system in central nervous system disorders and aging

Robert Zivadinov, Chih-Ping Chung

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Simple steps to equity in child survival

Stuart Gilmour, Kenji Shibuya

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The effectiveness of police custody assessments in identifying suspects with intellectual disabilities and attention deficit hyperactivity disorder

Susan Young, Emily J Goodwin, Ottilie Sedgwick, Gisli H Gudjonsson

01.12.2013 | Erratum | Ausgabe 1/2013 Open Access

Erratum to: Additional Saturday rehabilitation improves functional independence and quality of life and reduces length of stay: a randomized controlled trial

Casey L Peiris, Nora Shields, Natasha K Brusco, Jennifer J Watts, Nicholas F Taylor

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Multimorbidity in bipolar disorder and undertreatment of cardiovascular disease: a cross sectional study

Daniel J Smith, Daniel Martin, Gary McLean, Julie Langan, Bruce Guthrie, Stewart W Mercer

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Pre-hypertension: another 'pseudodisease’?

Pascal Meier, Franz H Messerli, Andreas Baumbach, Alexandra J Lansky

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Allergen immunotherapy and allergic rhinitis: false beliefs

Moisés A Calderón, A William Frankland, Pascal Demoly

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Quantifying circulating hypoxia-induced RNA transcripts in maternal blood to determine in uterofetal hypoxic status

Clare Whitehead, Wan Tinn Teh, Susan P Walker, Cheryl Leung, Sonali Mendis, Luke Larmour, Stephen Tong

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Can breastfeeding promote child health equity? A comprehensive analysis of breastfeeding patterns across the developing world and what we can learn from them

Thomas J Roberts, Emily Carnahan, Emmanuela Gakidou

01.12.2013 | Question and Answer | Ausgabe 1/2013 Open Access

The DSM-5 - an interview with David Kupfer

David Kupfer

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Approach to the older patient with cancer

Maxine de la Cruz, Eduardo Bruera

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Prehypertension and incidence of cardiovascular disease: a meta-analysis

Yuli Huang, Sheng Wang, Xiaoyan Cai, Weiyi Mai, Yunzhao Hu, Hongfeng Tang, Dingli Xu

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Efficacy of prosultiamine treatment in patients with human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: results from an open-label clinical trial

Tatsufumi Nakamura, Tomohiro Matsuo, Taku Fukuda, Shinji Yamato, Kentaro Yamaguchi, Ikuo Kinoshita, Toshio Matsuzaki, Yoshihiro Nishiura, Kunihiko Nagasato, Tomoko Narita-Masuda, Hideki Nakamura, Katsuya Satoh, Hitoshi Sasaki, Hideki Sakai, Atsushi Kawakami

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Therapeutic benefits of an oral vitamin B1 derivative for human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Jun-ichi Kira

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

The Hyperferritinemic Syndrome: macrophage activation syndrome, Still’s disease, septic shock and catastrophic antiphospholipid syndrome

Cristina Rosário, Gisele Zandman-Goddard, Esther G Meyron-Holtz, David P D’Cruz, Yehuda Shoenfeld

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Procalcitonin beyond the acute phase: novel biomediator properties?

Carolina Panico, Eric Nylen

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Rapid diagnostics of tuberculosis and drug resistance in the industrialized world: clinical and public health benefits and barriers to implementation

Francis Drobniewski, Vladyslav Nikolayevskyy, Horst Maxeiner, Yanina Balabanova, Nicola Casali, Irina Kontsevaya, Olga Ignatyeva

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Alcohol intake, wine consumption and the development of depression: the PREDIMED study

Alfredo Gea, Juan J Beunza, Ramón Estruch, Almudena Sánchez-Villegas, Jordi Salas-Salvadó, Pilar Buil-Cosiales, Enrique Gómez-Gracia, María-Isabel Covas, Dolores Corella, Miquel Fiol, Fernando Arós, José Lapetra, Rosa-María Lamuela-Raventós, Julia Wärnberg, Xavier Pintó, Lluis Serra-Majem, Miguel A Martínez-González, for the PREDIMED GROUP

01.12.2013 | Erratum | Ausgabe 1/2013 Open Access

Erratum to: Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial

Clifford J Bailey, Jorge L Gross, Delphine Hennicken, Nayyar Iqbal, Traci A Mansfield, James F List

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Is it smoking or related lifestyle variables that increase metabolic syndrome risk?

Mikael Rabaeus, Patricia Salen, Michel de Lorgeril

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

What is next after the genes for autoimmunity?

John Castiblanco, Mauricio Arcos-Burgos, Juan-Manuel Anaya

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

Gerwyn Morris, Michael Maes

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Comparing sociocultural features of cholera in three endemic African settings

Christian Schaetti, Neisha Sundaram, Sonja Merten, Said M Ali, Erick O Nyambedha, Bruno Lapika, Claire-Lise Chaignat, Raymond Hutubessy, Mitchell G Weiss

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study

Elin Strand, Eva R Pedersen, Gard FT Svingen, Hall Schartum-Hansen, Eirik W Rebnord, Bodil Bjørndal, Reinhard Seifert, Pavol Bohov, Klaus Meyer, J Kalervo Hiltunen, Jan E Nordrehaug, Dennis WT Nilsen, Rolf K Berge, Ottar Nygård

01.12.2013 | Minireview | Ausgabe 1/2013 Open Access

B. anthracisassociated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin components

Kenneth E Remy, Ping Qiu, Yan Li, Xizhong Cui, Peter Q Eichacker

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Venous endothelial injury in central nervous system diseases

Jonathan S Alexander, Leonard Prouty, Ikuo Tsunoda, Chaitanya Vijay Ganta, Alireza Minagar

01.12.2013 | Correspondence | Ausgabe 1/2013 Open Access

Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration

Lisa M McShane, Margaret M Cavenagh, Tracy G Lively, David A Eberhard, William L Bigbee, P Mickey Williams, Jill P Mesirov, Mei-Yin C Polley, Kelly Y Kim, James V Tricoli, Jeremy MG Taylor, Deborah J Shuman, Richard M Simon, James H Doroshow, Barbara A Conley

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

OMICS-based personalized oncology: if it is worth doing, it is worth doing well!

Daniel F Hayes

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

DNA barcoding detects contamination and substitution in North American herbal products

Steven G Newmaster, Meghan Grguric, Dhivya Shanmughanandhan, Sathishkumar Ramalingam, Subramanyam Ragupathy

01.12.2013 | Forum | Ausgabe 1/2013 Open Access

Global health: the importance of evidence-based medicine

Gretchen L Birbeck, Charles S Wiysonge, Edward J Mills, Julio J Frenk, Xiao-Nong Zhou, Prabhat Jha

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Millennium Development Goals 4 and 5: progress and challenges

Jennifer Bryce, Robert E Black, Cesar G Victora

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Secular trends in new childhood epidemics: insights from evolutionary medicine

Martin Brüne, Ze’ev Hochberg

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Impact of a population-based HPV vaccination program on cervical abnormalities: a data linkage study

Dorota M Gertig, Julia ML Brotherton, Alison C Budd, Kelly Drennan, Genevieve Chappell, A Marion Saville

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity

Michael K Skinner, Mohan Manikkam, Rebecca Tracey, Carlos Guerrero-Bosagna, Muksitul Haque, Eric E Nilsson

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Magnesium deficit - overlooked cause of low vitamin D status?

Armin Zittermann

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

HIV-associated tuberculosis: relationship between disease severity and the sensitivity of new sputum-based and urine-based diagnostic assays

Stephen D Lawn, Andrew D Kerkhoff, Monica Vogt, Robin Wood

01.12.2013 | Opinion | Ausgabe 1/2013 Open Access

Implications of the licensure of a partially efficacious malaria vaccine on evaluating second-generation vaccines

Freya JI Fowkes, Julie A Simpson, James G Beeson

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Irisin and exercise training in humans – Results from a randomized controlled training trial

Anne Hecksteden, Melissa Wegmann, Anke Steffen, Jochen Kraushaar, Arne Morsch, Sandra Ruppenthal, Lars Kaestner, Tim Meyer

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Adverse drug reactions and off-label and unlicensed medicines in children: a nested case?control study of inpatients in a pediatric hospital

Jennifer R Bellis, Jamie J Kirkham, Signe Thiesen, Elizabeth J Conroy, Louise E Bracken, Helena L Mannix, Kim A Bird, Jennifer C Duncan, Matthew Peak, Mark A Turner, Rosalind L Smyth, Anthony J Nunn, Munir Pirmohamed

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

Diagnostic indicators of non-cardiovascular chest pain: a systematic review and meta-analysis

Maria M Wertli, Katrin B Ruchti, Johann Steurer, Ulrike Held

01.12.2013 | Research article | Ausgabe 1/2013 Open Access

The contribution of major depression to the global burden of ischemic heart disease: a comparative risk assessment

Fiona J Charlson, Andrew E Moran, Greg Freedman, Rosana E Norman, Nicolas JC Stapelberg, Amanda J Baxter, Theo Vos, Harvey A Whiteford

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Management of HIV-associated tuberculosis in resource-limited settings: a state-of-the-art review

Stephen D Lawn, Graeme Meintjes, Helen McIlleron, Anthony D Harries, Robin Wood

01.12.2013 | Debate | Ausgabe 1/2013 Open Access

Challenges in cardiac device innovation: is neuroimaging an appropriate endpoint? Consensus from the 2013 Yale-UCL Cardiac Device Innovation Summit

Stephanie M Meller, Andreas Baumbach, Szilard Voros, Michael Mullen, Alexandra J Lansky

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