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Zeitschrift

BMC Medicine

BMC Medicine 1/2017

Ausgabe 1/2017

Inhaltsverzeichnis ( 223 Artikel )

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight

Kris Genelyn Dimasuay, Elizabeth H. Aitken, Fredrick Rosario, Madi Njie, Jocelyn Glazier, Stephen J. Rogerson, Freya J. I. Fowkes, James G. Beeson, Theresa Powell, Thomas Jansson, Philippe Boeuf

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Unraveling the associations of age and menopause with cardiovascular risk factors in a large population-based study

A. C. de Kat, V. Dam, N. C. Onland-Moret, M. J. C. Eijkemans, F. J. M. Broekmans, Y. T. van der Schouw

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Characteristics and knowledge synthesis approach for 456 network meta-analyses: a scoping review

Wasifa Zarin, Areti Angeliki Veroniki, Vera Nincic, Afshin Vafaei, Emily Reynen, Sanober S. Motiwala, Jesmin Antony, Shannon M. Sullivan, Patricia Rios, Caitlin Daly, Joycelyne Ewusie, Maria Petropoulou, Adriani Nikolakopoulou, Anna Chaimani, Georgia Salanti, Sharon E. Straus, Andrea C. Tricco

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Preoperative optimization of patient expectations improves long-term outcome in heart surgery patients: results of the randomized controlled PSY-HEART trial

Winfried Rief, Meike C. Shedden-Mora, Johannes A. C. Laferton, Charlotte Auer, Keith J. Petrie, Stefan Salzmann, Manfred Schedlowski, Rainer Moosdorf

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

About the complexity of adult onset Still’s disease… and advances still required for its management

Philippe Guilpain, Alain Le Quellec

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model

Maik Pietzner, Beatrice Engelmann, Tim Kacprowski, Janine Golchert, Anna-Luise Dirk, Elke Hammer, K. Alexander Iwen, Matthias Nauck, Henri Wallaschofski, Dagmar Führer, Thomas F. Münte, Nele Friedrich, Uwe Völker, Georg Homuth, Georg Brabant

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress

Aadil Bharwani, M. Firoz Mian, Michael G. Surette, John Bienenstock, Paul Forsythe

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Steroid withdrawal after renal transplantation: a retrospective cohort study

Maria C. Haller, Michael Kammer, Alexander Kainz, Heather J. Baer, Georg Heinze, Rainer Oberbauer

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

The Journal Impact Factor is under attack – use the CAPCI factor instead

Eleftherios P. Diamandis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Health-related quality of life and psychological distress among cancer survivors in Southeast Asia: results from a longitudinal study in eight low- and middle-income countries

The ACTION Study Group

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Post-stroke dementia – a comprehensive review

Milija D. Mijajlović, Aleksandra Pavlović, Michael Brainin, Wolf-Dieter Heiss, Terence J. Quinn, Hege B. Ihle-Hansen, Dirk M. Hermann, Einor Ben Assayag, Edo Richard, Alexander Thiel, Efrat Kliper, Yong-Il Shin, Yun-Hee Kim, SeongHye Choi, San Jung, Yeong-Bae Lee, Osman Sinanović, Deborah A. Levine, Ilana Schlesinger, Gillian Mead, Vuk Milošević, Didier Leys, Guri Hagberg, Marie Helene Ursin, Yvonne Teuschl, Semyon Prokopenko, Elena Mozheyko, Anna Bezdenezhnykh, Karl Matz, Vuk Aleksić, DafinFior Muresanu, Amos D. Korczyn, Natan M. Bornstein

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Lifetime and 12-month prevalence of eating disorders amongst women in mid-life: a population-based study of diagnoses and risk factors

Nadia Micali, Maria G. Martini, Jennifer J. Thomas, Kamryn T. Eddy, Radha Kothari, Ellie Russell, Cynthia M. Bulik, Janet Treasure

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Can screening instruments accurately determine poor outcome risk in adults with recent onset low back pain? A systematic review and meta-analysis

Emma L. Karran, James H. McAuley, Adrian C. Traeger, Susan L. Hillier, Luzia Grabherr, Leslie N. Russek, G. Lorimer Moseley

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Closed-loop for type 1 diabetes – an introduction and appraisal for the generalist

Lia Bally, Hood Thabit, Roman Hovorka

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Procalcitonin-guided diagnosis and antibiotic stewardship revisited

Ramon Sager, Alexander Kutz, Beat Mueller, Philipp Schuetz

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Translational models for vascular cognitive impairment: a review including larger species

Atticus H. Hainsworth, Stuart M. Allan, Johannes Boltze, Catriona Cunningham, Chad Farris, Elizabeth Head, Masafumi Ihara, Jeremy D. Isaacs, Raj N. Kalaria, Saskia A. M. J. Lesnik Oberstein, Mark B. Moss, Björn Nitzsche, Gary A. Rosenberg, Julie W. Rutten, Melita Salkovic-Petrisic, Aron M. Troen

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

A step forward in addressing cancer survivorship in the Asia-Pacific region

Raymond Javan Chan, Alexandre Chan, Patsy Yates, Alex Molassiotis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

Daniel R. Morales, Brian J. Lipworth, Peter T. Donnan, Cathy Jackson, Bruce Guthrie

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Which patients with advanced respiratory disease die in hospital? A 14-year population-based study of trends and associated factors

Irene J. Higginson, Charles C. Reilly, Sabrina Bajwah, Matthew Maddocks, Massimo Costantini, Wei Gao, on behalf of the GUIDE_Care project

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Risk estimates of recurrent congenital anomalies in the UK: a population-based register study

Svetlana V. Glinianaia, Peter W. G. Tennant, Judith Rankin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

What is the association of hypothyroidism with risks of cardiovascular events and mortality? A meta-analysis of 55 cohort studies involving 1,898,314 participants

Yu Ning, Yun J. Cheng, Li J. Liu, Jaskanwal D. S. Sara, Zhi Y. Cao, Wei P. Zheng, Tian S. Zhang, Hui J. Han, Zhen Y. Yang, Yi Zhang, Fei L. Wang, Rui Y. Pan, Jie L. Huang, Ling L. Wu, Ming Zhang, Yong X. Wei

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Comparison of the effects of fibrates versus statins on plasma lipoprotein(a) concentrations: a systematic review and meta-analysis of head-to-head randomized controlled trials

Amirhossein Sahebkar, Luis E. Simental-Mendía, Gerald F. Watts, Maria-Corina Serban, Maciej Banach, Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A randomised controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial)

Felice N. Jacka, Adrienne O’Neil, Rachelle Opie, Catherine Itsiopoulos, Sue Cotton, Mohammedreza Mohebbi, David Castle, Sarah Dash, Cathrine Mihalopoulos, Mary Lou Chatterton, Laima Brazionis, Olivia M. Dean, Allison M. Hodge, Michael Berk

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A realist review of mobile phone-based health interventions for non-communicable disease management in sub-Saharan Africa

Daniel Opoku, Victor Stephani, Wilm Quentin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The efficacy of Protected Mealtimes in hospitalised patients: a stepped wedge cluster randomised controlled trial

Judi Porter, Terry P. Haines, Helen Truby

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort

Renée T. Fortner, Danja Sarink, Helena Schock, Theron Johnson, Anne Tjønneland, Anja Olsen, Kim Overvad, Aurélie Affret, Mathilde His, Marie-Christine Boutron-Ruault, Heiner Boeing, Antonia Trichopoulou, Androniki Naska, Philippos Orfanos, Domenico Palli, Sabina Sieri, Amalia Mattiello, Rosario Tumino, Fulvio Ricceri, H. Bas Bueno-de-Mesquita, Petra H. M. Peeters, Carla H. Van Gils, Elisabete Weiderpass, Eiliv Lund, J. Ramón Quirós, Antonio Agudo, Maria-José Sánchez, María-Dolores Chirlaque, Eva Ardanaz, Miren Dorronsoro, Tim Key, Kay-Tee Khaw, Sabina Rinaldi, Laure Dossus, Marc Gunter, Melissa A. Merritt, Elio Riboli, Rudolf Kaaks

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer’s disease

Branko Malojcic, Panteleimon Giannakopoulos, Farzaneh A. Sorond, Elsa Azevedo, Marina Diomedi, Janja Pretnar Oblak, Nicola Carraro, Marina Boban, Laszlo Olah, Stephan J. Schreiber, Aleksandra Pavlovic, Zsolt Garami, Nantan M. Bornstein, Bernhard Rosengarten

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Potential predatory and legitimate biomedical journals: can you tell the difference? A cross-sectional comparison

Larissa Shamseer, David Moher, Onyi Maduekwe, Lucy Turner, Virginia Barbour, Rebecca Burch, Jocalyn Clark, James Galipeau, Jason Roberts, Beverley J. Shea

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Practical guide to exocrine pancreatic insufficiency – Breaking the myths

Maarten R. Struyvenberg, Camilia R. Martin, Steven D. Freedman

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Infant fungal communities: current knowledge and research opportunities

Tonya L. Ward, Dan Knights, Cheryl A. Gale

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Cost-effectiveness of screening for ovarian cancer amongst postmenopausal women: a model-based economic evaluation

Ben Kearns, Jim Chilcott, Sophie Whyte, Louise Preston, Susi Sadler

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The effect of an antenatal lifestyle intervention in overweight and obese women on circulating cardiometabolic and inflammatory biomarkers: secondary analyses from the LIMIT randomised trial

Lisa J. Moran, Louise M. Fraser, Tulika Sundernathan, Andrea R. Deussen, Jennie Louise, Lisa N. Yelland, Rosalie M. Grivell, Anne Macpherson, Matthew W. Gillman, Jeffrey S. Robinson, Julie A. Owens, Jodie M. Dodd

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Financial barriers and adverse clinical outcomes among patients with cardiovascular-related chronic diseases: a cohort study

David J. T. Campbell, Braden J. Manns, Robert G. Weaver, Brenda R. Hemmelgarn, Kathryn M. King-Shier, Claudia Sanmartin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery

Lucia Martinez de la Escalera, Ioannis Kyrou, Jana Vrbikova, Voitech Hainer, Petra Sramkova, Martin Fried, Milan K. Piya, Sudhesh Kumar, Gyanendra Tripathi, Philip G. McTernan

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pain relief that matters to patients: systematic review of empirical studies assessing the minimum clinically important difference in acute pain

Mette Frahm Olsen, Eik Bjerre, Maria Damkjær Hansen, Jørgen Hilden, Nino Emanuel Landler, Britta Tendal, Asbjørn Hróbjartsson

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

When is proton pump inhibitor use appropriate?

Rena Yadlapati, Peter J. Kahrilas

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach

Amélie Bonnefond, Loïc Yengo, Aurélie Dechaume, Mickaël Canouil, Maxime Castelain, Estelle Roger, Frédéric Allegaert, Robert Caiazzo, Violeta Raverdy, Marie Pigeyre, Abdelilah Arredouani, Jean-Michel Borys, Claire Lévy-Marchal, Jacques Weill, Ronan Roussel, Beverley Balkau, Michel Marre, François Pattou, Thierry Brousseau, Philippe Froguel

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Food for thought: why does the medical community struggle with research about nutritional therapy in the acute care setting?

Philipp Schuetz

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects

Cajsa Davegårdh, Christa Broholm, Alexander Perfilyev, Tora Henriksen, Sonia García-Calzón, Lone Peijs, Ninna Schiøler Hansen, Petr Volkov, Rasmus Kjøbsted, Jørgen F. P. Wojtaszewski, Maria Pedersen, Bente Klarlund Pedersen, Dov B. Ballak, Charles A. Dinarello, Bas Heinhuis, Leo A. B. Joosten, Emma Nilsson, Allan Vaag, Camilla Scheele, Charlotte Ling

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Intranasal oxytocin reduces provoked symptoms in female patients with posttraumatic stress disorder despite exerting sympathomimetic and positive chronotropic effects in a randomized controlled trial

M. Sack, D. Spieler, L. Wizelman, G. Epple, J. Stich, M. Zaba, U. Schmidt

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) as a model of small vessel disease: update on clinical, diagnostic, and management aspects

Ilaria Di Donato, Silvia Bianchi, Nicola De Stefano, Martin Dichgans, Maria Teresa Dotti, Marco Duering, Eric Jouvent, Amos D. Korczyn, Saskia A. J. Lesnik-Oberstein, Alessandro Malandrini, Hugh S. Markus, Leonardo Pantoni, Silvana Penco, Alessandra Rufa, Osman Sinanović, Dragan Stojanov, Antonio Federico

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Perspectives on model forecasts of the 2014–2015 Ebola epidemic in West Africa: lessons and the way forward

Gerardo Chowell, Cécile Viboud, Lone Simonsen, Stefano Merler, Alessandro Vespignani

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Genome editing for inborn errors of metabolism: advancing towards the clinic

Jessica L. Schneller, Ciaran M. Lee, Gang Bao, Charles P. Venditti

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Can screening instruments accurately determine poor outcome risk in adults with recent onset low back pain? A systematic review and meta-analysis

Emma L. Karran, James H. McAuley, Adrian C. Traeger, Susan L. Hillier, Luzia Grabherr, Leslie N. Russek, G. Lorimer Moseley

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Non-alcoholic fatty liver disease

Brent A. Neuschwander-Tetri

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The evaluating self-management and educational support in severely obese patients awaiting multidisciplinary bariatric care (EVOLUTION) trial: principal results

Raj S. Padwal, Scott Klarenbach, Arya M. Sharma, Miriam Fradette, Susan E. Jelinski, Alun Edwards, Sumit R. Majumdar

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Counting the lives saved by DOTS in India: a model-based approach

Sandip Mandal, Vineet K. Chadha, Ramanan Laxminarayan, Nimalan Arinaminpathy

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Genetics of vascular dementia – review from the ICVD working group

M. Arfan Ikram, Anna Bersano, Raquel Manso-Calderón, Jian-Ping Jia, Helena Schmidt, Lefkos Middleton, Benedetta Nacmias, Saima Siddiqi, Hieab H.H. Adams

01.12.2017 | Debate | Ausgabe 1/2017 Open Access

Innovative regenerative medicines in the EU: a better future in evidence?

Mark S. Corbett, Andrew Webster, Robert Hawkins, Nerys Woolacott

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome

Xinyi Lin, Ives Yubin Lim, Yonghui Wu, Ai Ling Teh, Li Chen, Izzuddin M. Aris, Shu E. Soh, Mya Thway Tint, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Michael S. Kobor, Michael J. Meaney, Keith M. Godfrey, Yap Seng Chong, Joanna D. Holbrook, Yung Seng Lee, Peter D. Gluckman, Neerja Karnani, on behalf of the GUSTO study group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A unique pattern of cortical connectivity characterizes patients with attention deficit disorders: a large electroencephalographic coherence study

Frank H. Duffy, Aditi Shankardass, Gloria B. McAnulty, Heidelise Als

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Hepatitis C-related hepatocellular carcinoma in the era of new generation antivirals

Thomas F. Baumert, Frank Jühling, Atsushi Ono, Yujin Hoshida

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Elimination of Hepatitis B: Is It a Mission Possible?

Tai-Chung Tseng, Jia-Horng Kao

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Cardiovascular risk factors are major determinants of thrombotic risk in patients with the lupus anticoagulant

Florian Posch, Johanna Gebhart, Jacob H. Rand, Silvia Koder, Peter Quehenberger, Vittorio Pengo, Cihan Ay, Ingrid Pabinger

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Successes and failures: what did we learn from recent first-line treatment immunotherapy trials in non-small cell lung cancer?

Jordi Remon, Benjamin Besse, Jean-Charles Soria

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Metabolomics approaches in pancreatic adenocarcinoma: tumor metabolism profiling predicts clinical outcome of patients

S. Battini, F. Faitot, A. Imperiale, A. E. Cicek, C. Heimburger, G. Averous, P. Bachellier, I. J. Namer

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

News from the melanoma sessions of the European Cancer Congress 2017

Piotr Rutkowski, Katarzyna Kozak

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Are potentially clinically meaningful benefits misinterpreted in cardiovascular randomized trials? A systematic examination of statistical significance, clinical significance, and authors’ conclusions

G. Michael Allan, Caitlin R. Finley, James McCormack, Vivek Kumar, Simon Kwong, Emelie Braschi, Christina Korownyk, Michael R. Kolber, Adriennne J. Lindblad, Oksana Babenko, Scott Garrison

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Allopurinol and the risk of ventricular arrhythmias in the elderly: a study using US Medicare data

Jasvinder A. Singh, John Cleveland

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility

Dimitrios Korbakis, Christina Schiza, Davor Brinc, Antoninus Soosaipillai, Theano D. Karakosta, Christine Légaré, Robert Sullivan, Brendan Mullen, Keith Jarvi, Eleftherios P. Diamandis, Andrei P. Drabovich

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Characteristics and knowledge synthesis approach for 456 network meta-analyses: a scoping review

Wasifa Zarin, Areti Angeliki Veroniki, Vera Nincic, Afshin Vafaei, Emily Reynen, Sanober S. Motiwala, Jesmin Antony, Shannon M. Sullivan, Patricia Rios, Caitlin Daly, Joycelyne Ewusie, Maria Petropoulou, Adriani Nikolakopoulou, Anna Chaimani, Georgia Salanti, Sharon E. Straus, Andrea C. Tricco

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The association between the day of the week of milestones in the care pathway of patients with hip fracture and 30-day mortality: findings from a prospective national registry – The National Hip Fracture Database of England and Wales

Adrian Sayers, Michael R. Whitehouse, James R. Berstock, Karen A. Harding, Michael B. Kelly, Timothy J. Chesser

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Can incontinence be cured? A systematic review of cure rates

Rob Riemsma, Suzanne Hagen, Ruth Kirschner-Hermanns, Christine Norton, Helle Wijk, Karl-Erik Andersson, Christopher Chapple, Julian Spinks, Adrian Wagg, Edward Hutt, Kate Misso, Sohan Deshpande, Jos Kleijnen, Ian Milsom

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Systematic meta-review of supported self-management for asthma: a healthcare perspective

Hilary Pinnock, Hannah L. Parke, Maria Panagioti, Luke Daines, Gemma Pearce, Eleni Epiphaniou, Peter Bower, Aziz Sheikh, Chris J. Griffiths, Stephanie J. C. Taylor, for the PRISMS and RECURSIVE groups

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial

Thomas M. Gill, Daniel P. Beavers, Jack M. Guralnik, Marco Pahor, Roger A. Fielding, Michelle Hauser, Todd M. Manini, Anthony P. Marsh, Mary M. McDermott, Anne B. Newman, Heather G. Allore, Michael E. Miller, for the LIFE Study Investigators

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Predicting fitness to practise events in international medical graduates who registered as UK doctors via the Professional and Linguistic Assessments Board (PLAB) system: a national cohort study

Paul A. Tiffin, Lewis W. Paton, Lazaro M. Mwandigha, John C. McLachlan, Jan Illing

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: a prospective cohort

Stephen D. Lawn, Andrew D. Kerkhoff, Rosie Burton, Charlotte Schutz, Andrew Boulle, Monica Vogt, Ankur Gupta-Wright, Mark P. Nicol, Graeme Meintjes

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models

Shakila Thangaratinam, John Allotey, Nadine Marlin, Julie Dodds, Fiona Cheong-See, Peter von Dadelszen, Wessel Ganzevoort, Joost Akkermans, Sally Kerry, Ben W. Mol, Karl G. M. Moons, Richard D. Riley, Khalid S. Khan, for the PREP Collaborative Network

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

The 2016 classification criteria for primary Sjogren’s syndrome: what’s new?

Franco Franceschini, Ilaria Cavazzana, Laura Andreoli, Angela Tincani

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Treatment duration of febrile urinary tract infection: a pragmatic randomized, double-blind, placebo-controlled non-inferiority trial in men and women

Cees van Nieuwkoop, Willize E. van der Starre, Janneke E. Stalenhoef, Anna M. van Aartrijk, Tanny J. K. van der Reijden, Albert M. Vollaard, Nathalie M. Delfos, Jan W. van ’t Wout, Jeanet W. Blom, Ida C. Spelt, Eliane M. S. Leyten, Ted Koster, Hans C. Ablij, Martha T. van der Beek, Mirjam J. Knol, Jaap T. van Dissel

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial

Adam A. Witney, Anna L. E. Bateson, Amina Jindani, Patrick P. J. Phillips, David Coleman, Neil G. Stoker, Philip D. Butcher, Timothy D. McHugh, RIFAQUIN Study Team

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study

Veronika Fedirko, Hao Quang Tran, Andrew T. Gewirtz, Magdalena Stepien, Antonia Trichopoulou, Krasimira Aleksandrova, Anja Olsen, Anne Tjønneland, Kim Overvad, Franck Carbonnel, Marie-Christine Boutron-Ruault, Gianluca Severi, Tilman Kühn, Rudolf Kaaks, Heiner Boeing, Christina Bamia, Pagona Lagiou, Sara Grioni, Salvatore Panico, Domenico Palli, Rosario Tumino, Alessio Naccarati, Petra H. Peeters, H. B. Bueno-de-Mesquita, Elisabete Weiderpass, José María Huerta Castaño, Aurelio Barricarte, María-José Sánchez, Miren Dorronsoro, J. Ramón Quirós, Antonio Agudo, Klas Sjöberg, Bodil Ohlsson, Oskar Hemmingsson, Mårten Werner, Kathryn E. Bradbury, Kay-Tee Khaw, Nick Wareham, Konstantinos K. Tsilidis, Dagfinn Aune, Augustin Scalbert, Isabelle Romieu, Elio Riboli, Mazda Jenab

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

eHealth in the future of medications management: personalisation, monitoring and adherence

Josip Car, Woan Shin Tan, Zhilian Huang, Peter Sloot, Bryony Dean Franklin

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Unraveling the associations of age and menopause with cardiovascular risk factors in a large population-based study

A. C. de Kat, V. Dam, N. C. Onland-Moret, M. J. C. Eijkemans, F. J. M. Broekmans, Y. T. van der Schouw

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Emerging concepts in liquid biopsies

Samantha Perakis, Michael R. Speicher

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Addressing a clinical challenge: guidelines for the diagnosis and treatment of leishmaniasis

Naomi E. Aronson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Incentivised chronic disease management and the inverse equity hypothesis: findings from a longitudinal analysis of Scottish primary care practice-level data

Richard Lowrie, Alex McConnachie, Andrea E. Williamson, Evangelos Kontopantelis, Marie Forrest, Norman Lannigan, Stewart W. Mercer, Frances S. Mair

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Patterns of care and outcomes of patients with METAstatic soft tissue SARComa in a real-life setting: the METASARC observational study

Marion Savina, Axel Le Cesne, Jean-Yves Blay, Isabelle Ray-Coquard, Olivier Mir, Maud Toulmonde, Sophie Cousin, Philippe Terrier, Dominique Ranchere-Vince, Pierre Meeus, Eberhard Stoeckle, Charles Honoré, Paul Sargos, Marie-Pierre Sunyach, Cécile Le Péchoux, Antoine Giraud, Carine Bellera, François Le Loarer, Antoine Italiano

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

S100β as a serum marker in endocrine resistant breast cancer

Sara Charmsaz, Éamon Hughes, Fiona T. Bane, Paul Tibbitts, Marie McIlroy, Christopher Byrne, Sinéad Cocchiglia, Jean McBryan, Bryan T. Hennessy, Róisín M. Dwyer, Michael J. Kerin, Arnold D. Hill, Leonie S. Young

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

The new field of ‘precision psychiatry’

Brisa S. Fernandes, Leanne M. Williams, Johann Steiner, Marion Leboyer, André F. Carvalho, Michael Berk

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Antidepressant use and cognitive decline in community-dwelling elderly people – The Three-City Cohort

Isabelle Carrière, Joanna Norton, Amandine Farré, Marilyn Wyart, Christophe Tzourio, Pernelle Noize, Karine Pérès, Annie Fourrier-Réglat, Karen Ritchie, Marie Laure Ancelin

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Successes and failures: what did we learn from recent first-line treatment immunotherapy trials in non-small cell lung cancer?

Jordi Remon, Benjamin Besse, Jean-Charles Soria

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Accuracy of low-density lipoprotein cholesterol estimation at very low levels

Renato Quispe, Aditya Hendrani, Mohamed B. Elshazly, Erin D. Michos, John W. McEvoy, Michael J. Blaha, Maciej Banach, Krishnaji R. Kulkarni, Peter P. Toth, Josef Coresh, Roger S. Blumenthal, Steven R. Jones, Seth S. Martin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis

Xin-Lin Zhang, Qing-Qing Zhu, Jing-Jing Yang, Yu-Han Chen, Yang Li, Su-Hui Zhu, Jun Xie, Lian Wang, Li-Na Kang, Biao Xu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Efavirenz-based simplification after successful early lopinavir-boosted-ritonavir-based therapy in HIV-infected children in Burkina Faso and Côte d’Ivoire: the MONOD ANRS 12206 non-inferiority randomised trial

Désiré Lucien Dahourou, Madeleine Amorissani-Folquet, Karen Malateste, Clarisse Amani-Bosse, Malik Coulibaly, Carole Seguin-Devaux, Thomas Toni, Rasmata Ouédraogo, Stéphane Blanche, Caroline Yonaba, François Eboua, Philippe Lepage, Divine Avit, Sylvie Ouédraogo, Philippe Van de Perre, Sylvie N’Gbeche, Angèle Kalmogho, Roger Salamon, Nicolas Meda, Marguerite Timité-Konan, Valériane Leroy, on behalf of the MONOD Study Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The relative importance of large problems far away versus small problems closer to home: insights into limiting the spread of antimicrobial resistance in England

Tjibbe Donker, Katherine L. Henderson, Katie L. Hopkins, Andrew R. Dodgson, Stephanie Thomas, Derrick W. Crook, Tim E. A. Peto, Alan P. Johnson, Neil Woodford, A. Sarah Walker, Julie V. Robotham

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effects of unconditional cash transfers on the outcome of treatment for severe acute malnutrition (SAM): a cluster-randomised trial in the Democratic Republic of the Congo

Emmanuel Grellety, Pélagie Babakazo, Amina Bangana, Gustave Mwamba, Ines Lezama, Noël Marie Zagre, Eric-Alain Ategbo

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes

Rajashree Mishra, Alessandra Chesi, Diana L. Cousminer, Mohammad I. Hawa, Jonathan P. Bradfield, Kenyaita M. Hodge, Vanessa C. Guy, Hakon Hakonarson, Didac Mauricio, Nanette C. Schloot, Knud B. Yderstræde, Benjamin F. Voight, Stanley Schwartz, Bernhard O. Boehm, Richard David Leslie, Struan F. A. Grant, Bone Mineral Density in Childhood Study

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children

Emily M. Teshome, Pauline E. A. Andang’o, Victor Osoti, Sofie R. Terwel, Walter Otieno, Ayşe Y. Demir, Andrew M. Prentice, Hans Verhoef

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Disease management in the treatment of patients with chronic heart failure who have universal access to health care: a randomized controlled trial

Ofra Kalter-Leibovici, Dov Freimark, Laurence S. Freedman, Galit Kaufman, Arnona Ziv, Havi Murad, Michal Benderly, Barbara G. Silverman, Nurit Friedman, Tali Cukierman-Yaffe, Elad Asher, Avishay Grupper, Dorit Goldman, Miriam Amitai, Shlomi Matetzky, Mordechai Shani, Haim Silber, for the Israel Heart Failure Disease Management Study (IHF-DMS) investigators

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Application of real-time global media monitoring and ‘derived questions’ for enhancing communication by regulatory bodies: the case of human papillomavirus vaccines

Priya Bahri, Julianna Fogd, Daniel Morales, Xavier Kurz, on behalf of the ADVANCE consortium

01.12.2017 | Correspondence | Ausgabe 1/2017 Open Access

Late presentation of chronic viral hepatitis for medical care: a consensus definition

Stefan Mauss, Stanislas Pol, Maria Buti, Erika Duffell, Charles Gore, Jeffrey V. Lazarus, Hilje Logtenberg-van der Grient, Jens Lundgren, Antons Mozalevskis, Dorthe Raben, Eberhard Schatz, Stefan Wiktor, Jürgen K. Rockstroh, on behalf of the European consensus working group on late presentation for Viral Hepatitis Care

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Should all acutely ill children in primary care be tested with point-of-care CRP: a cluster randomised trial

Jan Y. Verbakel, Marieke B. Lemiengre, Tine De Burghgraeve, An De Sutter, Bert Aertgeerts, Bethany Shinkins, Rafael Perera, David Mant, Ann Van den Bruel, Frank Buntinx

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Expedited Partner Therapy (EPT) increases the frequency of partner notification among MSM in Lima, Peru: a pilot randomized controlled trial

Jesse L. Clark, Eddy R. Segura, Catherine E. Oldenburg, Jessica Rios, Silvia M. Montano, Amaya Perez-Brumer, Manuel Villaran, Jorge Sanchez, Thomas J. Coates, Javier R. Lama

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Comparative safety of anti-epileptic drugs during pregnancy: a systematic review and network meta-analysis of congenital malformations and prenatal outcomes

Areti Angeliki Veroniki, Elise Cogo, Patricia Rios, Sharon E. Straus, Yaron Finkelstein, Ryan Kealey, Emily Reynen, Charlene Soobiah, Kednapa Thavorn, Brian Hutton, Brenda R. Hemmelgarn, Fatemeh Yazdi, Jennifer D’Souza, Heather MacDonald, Andrea C. Tricco

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A cluster-randomized trial to reduce caesarean delivery rates in Quebec: cost-effectiveness analysis

Mira Johri, Edmond S. W. Ng, Clara Bermudez-Tamayo, Jeffrey S. Hoch, Thierry Ducruet, Nils Chaillet

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Habitual coffee consumption and genetic predisposition to obesity: gene-diet interaction analyses in three US prospective studies

Tiange Wang, Tao Huang, Jae H. Kang, Yan Zheng, Majken K. Jensen, Janey L. Wiggs, Louis R. Pasquale, Charles S. Fuchs, Hannia Campos, Eric B. Rimm, Walter C. Willett, Frank B. Hu, Lu Qi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Mediation of the effect of malaria in pregnancy on stillbirth and neonatal death in an area of low transmission: observational data analysis

Kerryn A. Moore, Freya J. I. Fowkes, Jacher Wiladphaingern, Nan San Wai, Moo Kho Paw, Mupawjay Pimanpanarak, Verena I. Carrara, Jathee Raksuansak, Julie A. Simpson, Nicholas J. White, François Nosten, Rose McGready

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Micronutrient powders to combat anemia in young children: does it work?

Frank T. Wieringa

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Observational studies: goldmines of information on rare diseases

Robert S. Benjamin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

Jasper Wouters, Miguel Vizoso, Anna Martinez-Cardus, F. Javier Carmona, Olivier Govaere, Teresa Laguna, Jesuchristopher Joseph, Peter Dynoodt, Claudia Aura, Mona Foth, Roy Cloots, Karin van den Hurk, Balazs Balint, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan, Karin Jirström, Bjorn Nodin, Girish Mallya-Udupi, Joost J. van den Oord, William M. Gallagher, Manel Esteller

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

How many people will need palliative care in 2040? Past trends, future projections and implications for services

S. N. Etkind, A. E. Bone, B. Gomes, N. Lovell, C. J. Evans, I. J. Higginson, F. E. M. Murtagh

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

ING3 promotes prostate cancer growth by activating the androgen receptor

Arash Nabbi, Urszula L. McClurg, Subhash Thalappilly, Amal Almami, Mahsa Mobahat, Tarek A. Bismar, Olivier Binda, Karl T. Riabowol

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Revisiting annual screening for latent tuberculosis infection in healthcare workers: a cost-effectiveness analysis

Guillaume A. Mullie, Kevin Schwartzman, Alice Zwerling, Dieynaba S. N’Diaye

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Recent household transmission of tuberculosis in England, 2010–2012: retrospective national cohort study combining epidemiological and molecular strain typing data

Maeve K. Lalor, Laura F. Anderson, Esther L. Hamblion, Andy Burkitt, Jennifer A. Davidson, Helen Maguire, Ibrahim Abubakar, H. Lucy Thomas

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

When less may be more: calorie restriction and response to cancer therapy

Ciara H. O’Flanagan, Laura A. Smith, Shannon B. McDonell, Stephen D. Hursting

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Towards the concept of disease-modifier in post-stroke or vascular cognitive impairment: a consensus report

Régis Bordet, Ralf Ihl, Amos D. Korczyn, Giuseppe Lanza, Jelka Jansa, Robert Hoerr, Alla Guekht

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

The genetics of gout: towards personalised medicine?

Nicola Dalbeth, Lisa K. Stamp, Tony R. Merriman

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Systemic treatment in advanced soft tissue sarcoma: what is standard, what is new

Anna Maria Frezza, Silvia Stacchiotti, Alessandro Gronchi

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Immunotherapy in head and neck cancer: aiming at EXTREME precision

Petr Szturz, Jan B. Vermorken

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Spotlight on landmark oncology trials: the latest evidence and novel trial designs

Helena Earl, Stefano Molica, Piotr Rutkowski

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Number needed to treat (NNT) in clinical literature: an appraisal

Diogo Mendes, Carlos Alves, Francisco Batel-Marques

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Assessing the efficiency of catch-up campaigns for the introduction of pneumococcal conjugate vaccine: a modelling study based on data from PCV10 introduction in Kilifi, Kenya

Stefan Flasche, John Ojal, Olivier Le Polain de Waroux, Mark Otiende, Katherine L. O’Brien, Moses Kiti, D. James Nokes, W John Edmunds, J. Anthony G. Scott

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea

Louis Schofield, Lisa J. Ioannidis, Stephan Karl, Leanne J. Robinson, Qiao Y. Tan, Daniel P. Poole, Inoni Betuela, Danika L. Hill, Peter M. Siba, Diana S. Hansen, Ivo Mueller, Emily M. Eriksson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Tall height and obesity are associated with an increased risk of aggressive prostate cancer: results from the EPIC cohort study

Aurora Perez-Cornago, Paul N. Appleby, Tobias Pischon, Konstantinos K. Tsilidis, Anne Tjønneland, Anja Olsen, Kim Overvad, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Annika Steffen, Antonia Trichopoulou, Pagona Lagiou, Maria Kritikou, Vittorio Krogh, Domenico Palli, Carlotta Sacerdote, Rosario Tumino, H. Bas Bueno-de-Mesquita, Antonio Agudo, Nerea Larrañaga, Elena Molina-Portillo, Aurelio Barricarte, Maria-Dolores Chirlaque, J. Ramón Quirós, Pär Stattin, Christel Häggström, Nick Wareham, Kay-Tee Khaw, Julie A. Schmidt, Marc Gunter, Heinz Freisling, Dagfinn Aune, Heather Ward, Elio Riboli, Timothy J. Key, Ruth C. Travis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer

Tushar Tomar, Nicolette G. Alkema, Leroy Schreuder, Gert Jan Meersma, Tim de Meyer, Wim van Criekinge, Harry G. Klip, Heidi Fiegl, Els van Nieuwenhuysen, Ignace Vergote, Martin Widschwendter, Ed Schuuring, Ate G. J. van der Zee, Steven de Jong, G. Bea A. Wisman

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Influence of the number and timing of malaria episodes during pregnancy on prematurity and small-for-gestational-age in an area of low transmission

Kerryn A. Moore, Julie A. Simpson, Jacher Wiladphaingern, Aung Myat Min, Mupawjay Pimanpanarak, Moo Kho Paw, Jathee Raksuansak, Sasithon Pukrittayakamee, Freya J. I. Fowkes, Nicholas J. White, François Nosten, Rose McGready

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

Alexander L. R. Lubbock, Grant D. Stewart, Fiach C. O’Mahony, Alexander Laird, Peter Mullen, Marie O’Donnell, Thomas Powles, David J. Harrison, Ian M. Overton

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The effect of weekly specialist palliative care teleconsultations in patients with advanced cancer –a randomized clinical trial

Patrick D. Hoek, Henk J. Schers, Ewald M. Bronkhorst, Kris C. P. Vissers, Jeroen G. J. Hasselaar

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis

James A. Prior, Hoda Ranjbar, John Belcher, Sarah L. Mackie, Toby Helliwell, Jennifer Liddle, Christian D. Mallen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa

Polycarp Mogeni, Irene Omedo, Christopher Nyundo, Alice Kamau, Abdisalan Noor, Philip Bejon, on behalf of The Hotspot Group Authors

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pre-diagnostic metabolite concentrations and prostate cancer risk in 1077 cases and 1077 matched controls in the European Prospective Investigation into Cancer and Nutrition

Julie A. Schmidt, Georgina K. Fensom, Sabina Rinaldi, Augustin Scalbert, Paul N. Appleby, David Achaintre, Audrey Gicquiau, Marc J. Gunter, Pietro Ferrari, Rudolf Kaaks, Tilman Kühn, Anna Floegel, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Eleutherios Anifantis, Claudia Agnoli, Domenico Palli, Morena Trevisan, Rosario Tumino, H. Bas Bueno-de-Mesquita, Antonio Agudo, Nerea Larrañaga, Daniel Redondo-Sánchez, Aurelio Barricarte, José Maria Huerta, J. Ramón Quirós, Nick Wareham, Kay-Tee Khaw, Aurora Perez-Cornago, Mattias Johansson, Amanda J. Cross, Konstantinos K. Tsilidis, Elio Riboli, Timothy J. Key, Ruth C. Travis

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment options

Thomas Bardin, Pascal Richette

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Use of malaria rapid diagnostic tests by community health workers in Afghanistan: cluster randomised trial

Toby Leslie, Mark Rowland, Amy Mikhail, Bonnie Cundill, Barbara Willey, Asif Alokozai, Ismail Mayan, Anwar Hasanzai, Sayed Habibullah Baktash, Nader Mohammed, Molly Wood, Habib-u-Rahman Rahimi, Baptiste Laurent, Cyril Buhler, Christopher J. M. Whitty

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

About the practice of psychiatric euthanasia: a commentary

Jorge Lopez-Castroman

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Rapidly increasing end-of-life care needs: a timely warning

Geoffrey Mitchell

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Healthcare system responses to intimate partner violence in low and middle-income countries: evidence is growing and the challenges become clearer

Angela Taft, Manuela Colombini

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A nurse-delivered, clinic-based intervention to address intimate partner violence among low-income women in Mexico City: findings from a cluster randomized controlled trial

Jhumka Gupta, Kathryn L. Falb, Oriana Ponta, Ziming Xuan, Paola Abril Campos, Annabel Arellano Gomez, Jimena Valades, Gisele Cariño, Claudia Diaz Olavarrieta

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The prognostic value of lymph node yield in the earliest stage of colorectal cancer: a multicenter cohort study

Yara Backes, Sjoerd G. Elias, Bibie S. Bhoelan, John N. Groen, Jeroen van Bergeijk, Tom C. J. Seerden, Hendrikus J. M. Pullens, Bernhard W. M. Spanier, Joost M. J. Geesing, Koen Kessels, Marjon Kerkhof, Peter D. Siersema, Wouter H. de Vos tot Nederveen Cappel, Niels van Lelyveld, Frank H. J. Wolfhagen, Frank ter Borg, G. Johan A. Offerhaus, Miangela M. Lacle, Leon M. G. Moons, on behalf of the Dutch T1 CRC Working Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Resisting and tolerating P. falciparum in pregnancy under different malaria transmission intensities

Nicaise Tuikue Ndam, Emmanuel Mbuba, Raquel González, Pau Cisteró, Simon Kariuki, Esperança Sevene, María Rupérez, Ana Maria Fonseca, Anifa Vala, Sonia Maculuve, Alfons Jiménez, Llorenç Quintó, Peter Ouma, Michael Ramharter, John J. Aponte, Arsenio Nhacolo, Achille Massougbodji, Valerie Briand, Peter G. Kremsner, Ghyslain Mombo-Ngoma, Meghna Desai, Eusebio Macete, Michel Cot, Clara Menéndez, Alfredo Mayor

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes

Hubert Kolb, Stephan Martin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Can China achieve a one-third reduction in premature mortality from non-communicable diseases by 2030?

Yichong Li, Xinying Zeng, Jiangmei Liu, Yunning Liu, Shiwei Liu, Peng Yin, Jinlei Qi, Zhenping Zhao, Shicheng Yu, Yuehua Hu, Guangxue He, Alan D. Lopez, George F. Gao, Linhong Wang, Maigeng Zhou

01.12.2017 | Review | Ausgabe 1/2017 Open Access

The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome

Deborah R. Caswell, Charles Swanton

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Surrogate endpoints in oncology: when are they acceptable for regulatory and clinical decisions, and are they currently overused?

Robert Kemp, Vinay Prasad

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Biological embedding of childhood adversity: from physiological mechanisms to clinical implications

Anne E. Berens, Sarah K. G. Jensen, Charles A. Nelson III

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Ethics review in compassionate use

Jan Borysowski, Hans-Jörg Ehni, Andrzej Górski

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Impact of ischemic preconditioning on surgical treatment of brain tumors: a single-center, randomized, double-blind, controlled trial

Arthur H. A. Sales, Melanie Barz, Stefanie Bette, Benedikt Wiestler, Yu-Mi Ryang, Bernhard Meyer, Martin Bretschneider, Florian Ringel, Jens Gempt

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

The public health value of vaccines beyond efficacy: methods, measures and outcomes

A. Wilder-Smith, I. Longini, P. L. Zuber, T. Bärnighausen, W. J. Edmunds, N. Dean, V. Masserey Spicher, M. R. Benissa, B. D. Gessner

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

How accurate is the ‘Surprise Question’ at identifying patients at the end of life? A systematic review and meta-analysis

Nicola White, Nuriye Kupeli, Victoria Vickerstaff, Patrick Stone

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Epidemiology and outcomes of people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 10,014 admissions

Emma L. Reynish, Simona M. Hapca, Nicosha De Souza, Vera Cvoro, Peter T. Donnan, Bruce Guthrie

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

What works for whom in the management of diabetes in people living with dementia: a realist review

Frances Bunn, Claire Goodman, Peter Reece Jones, Bridget Russell, Daksha Trivedi, Alan Sinclair, Antony Bayer, Greta Rait, Jo Rycroft-Malone, Christopher Burton

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Detection of antibiotic resistance is essential for gonorrhoea point-of-care testing: a mathematical modelling study

Stephanie M. Fingerhuth, Nicola Low, Sebastian Bonhoeffer, Christian L. Althaus

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative

Dan J. Stein, Carmen C. W. Lim, Annelieke M. Roest, Peter de Jonge, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Corina Benjet, Evelyn J. Bromet, Ronny Bruffaerts, Giovanni de Girolamo, Silvia Florescu, Oye Gureje, Josep Maria Haro, Meredith G. Harris, Yanling He, Hristo Hinkov, Itsuko Horiguchi, Chiyi Hu, Aimee Karam, Elie G. Karam, Sing Lee, Jean-Pierre Lepine, Fernando Navarro-Mateu, Beth-Ellen Pennell, Marina Piazza, Jose Posada-Villa, Margreet ten Have, Yolanda Torres, Maria Carmen Viana, Bogdan Wojtyniak, Miguel Xavier, Ronald C. Kessler, Kate M. Scott, WHO World Mental Health Survey Collaborators

01.12.2017 | Review | Ausgabe 1/2017 Open Access

The renin–angiotensin system: a possible new target for depression

João Vian, Círia Pereira, Victor Chavarria, Cristiano Köhler, Brendon Stubbs, João Quevedo, Sung-Wan Kim, André F. Carvalho, Michael Berk, Brisa S. Fernandes

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The clinical utility of the urine-based lateral flow lipoarabinomannan assay in HIV-infected adults in Myanmar: an observational study

Swe Swe Thit, Ne Myo Aung, Zaw Win Htet, Mark A. Boyd, Htin Aung Saw, Nicholas M. Anstey, Tint Tint Kyi, David A. Cooper, Mar Mar Kyi, Josh Hanson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: a randomised controlled trial

Mahen Wijesuriya, Nikolaos Fountoulakis, Nicola Guess, Sarath Banneheka, Laksha Vasantharajah, Martin Gulliford, Giancarlo Viberti, Luigi Gnudi, Janaka Karalliedde

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis

Paulina Sypniewska, Jose F. Duda, Isabella Locatelli, Clotilde Rambaud Althaus, Fabrice Althaus, Blaise Genton

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pregnancy, pregnancy loss, and the risk of cardiovascular disease in Chinese women: findings from the China Kadoorie Biobank

Sanne A. E. Peters, Ling Yang, Yu Guo, Yiping Chen, Zheng Bian, Xiaocao Tian, Liang Chang, Shuo Zhang, Jiaqiu Liu, Tao Wang, Junshi Chen, Liming Li, Mark Woodward, Zhengming Chen, on behalf of the China Kadoorie Biobank collaboration group

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Country of qualification is linked to doctors’ General Medical Council performance assessment rate, but is it linked to their clinical competence?

Richard Wakeford

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Consistency and sources of divergence in recommendations on screening with questionnaires for presently experienced health problems or symptoms: a comparison of recommendations from the Canadian Task Force on Preventive Health Care, UK National Screening Committee, and US Preventive Services Task Force

Brett D. Thombs, Nazanin Saadat, Kira E. Riehm, Justin Michael Karter, Akansha Vaswani, Bonnie K. Andrews, Peter Simons, Lisa Cosgrove

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Characterizing measles transmission in India: a dynamic modeling study using verbal autopsy data

Stéphane Verguet, Edward O. Jones, Mira Johri, Shaun K. Morris, Wilson Suraweera, Cindy L. Gauvreau, Prabhat Jha, Mark Jit

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The contribution of risk factors to socioeconomic inequalities in multimorbidity across the lifecourse: a longitudinal analysis of the Twenty-07 cohort

Srinivasa Vittal Katikireddi, Kathryn Skivington, Alastair H. Leyland, Kate Hunt, Stewart W Mercer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Gestational hypertensive disorders and retinal microvasculature: the Generation R Study

Laura Benschop, Sarah Schalekamp–Timmermans, Jeanine E. Roeters van Lennep, Vincent W. V. Jaddoe, Tien Yin Wong, Carol Y. Cheung, Eric A. P. Steegers, M. Kamran Ikram

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Risk and predictors of psoriasis in patients with breast cancer: a Swedish population-based cohort study

Haomin Yang, Judith S. Brand, Jingmei Li, Jonas F. Ludvigsson, Emilio Ugalde-Morales, Flaminia Chiesa, Per Hall, Kamila Czene

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Intervention Now to Eliminate Repeat Unintended Pregnancy in Teenagers (INTERUPT): a systematic review of intervention effectiveness and cost-effectiveness, and qualitative and realist synthesis of implementation factors and user engagement

Rabeea’h W. Aslam, Maggie Hendry, Andrew Booth, Ben Carter, Joanna M. Charles, Noel Craine, Rhiannon Tudor Edwards, Jane Noyes, Lupetu Ives Ntambwe, Diana Pasterfield, Jo Rycroft-Malone, Nefyn Williams, Rhiannon Whitaker

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Ibrutinib continues to influence the therapeutic landscape of chronic lymphocytic leukemia: new data presented at ASCO 2017

Stefano Molica

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Circulating tumor DNA for personalized lung cancer monitoring

Clare Fiala, Eleftherios P. Diamandis

01.12.2017 | Minireview | Ausgabe 1/2017 Open Access

What makes gouty inflammation so variable?

Robert Terkeltaub

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

RETRACTED ARTICLE:The impact of repeated vaccination on influenza vaccine effectiveness: a systematic review and meta-analysis

Lauren C. Ramsay, Sarah A. Buchan, Robert G. Stirling, Benjamin J. Cowling, Shuo Feng, Jeffrey C. Kwong, Bryna F. Warshawsky

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Highlights in soft tissue sarcomas and gastrointestinal stromal tumours (GIST) trials reported at ASCO 2017 Annual Meeting

Anna Maria Frezza, Silvia Stacchiotti, Alessandro Gronchi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association of bariatric surgery with risk of acute care use for hypertension-related disease in obese adults: population-based self-controlled case series study

Yuichi J. Shimada, Yusuke Tsugawa, Hiroyasu Iso, David F. M. Brown, Kohei Hasegawa

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Trade-off between benefits, harms and economic efficiency of low-dose CT lung cancer screening: a microsimulation analysis of nodule management strategies in a population-based setting

Marina Treskova, Ines Aumann, Heiko Golpon, Jens Vogel-Claussen, Tobias Welte, Alexander Kuhlmann

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Gestational diabetes mellitus—right person, right treatment, right time?

Robert S. Lindsay, Sharon T. Mackin, Scott M. Nelson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Reduced growth velocity across the third trimester is associated with placental insufficiency in fetuses born at a normal birthweight: a prospective cohort study

Teresa M. MacDonald, Lisa Hui, Stephen Tong, Alice J. Robinson, Kirsten M. Dane, Anna L. Middleton, Susan P. Walker

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes

Jean-Philippe Foy, Louis Bazire, Sandra Ortiz-Cuaran, Sophie Deneuve, Janice Kielbassa, Emilie Thomas, Alain Viari, Alain Puisieux, Patrick Goudot, Chloé Bertolus, Nicolas Foray, Youlia Kirova, Pierre Verrelle, Pierre Saintigny

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Cost-effectiveness analysis of quadrivalent seasonal influenza vaccines in England

Dominic Thorrington, Edwin van Leeuwen, Mary Ramsay, Richard Pebody, Marc Baguelin

01.12.2017 | Correspondence | Ausgabe 1/2017 Open Access

Core competencies for scientific editors of biomedical journals: consensus statement

David Moher, James Galipeau, Sabina Alam, Virginia Barbour, Kidist Bartolomeos, Patricia Baskin, Sally Bell-Syer, Kelly D. Cobey, Leighton Chan, Jocalyn Clark, Jonathan Deeks, Annette Flanagin, Paul Garner, Anne-Marie Glenny, Trish Groves, Kurinchi Gurusamy, Farrokh Habibzadeh, Stefanie Jewell-Thomas, Diane Kelsall, José Florencio Lapeña Jr, Harriet MacLehose, Ana Marusic, Joanne E. McKenzie, Jay Shah, Larissa Shamseer, Sharon Straus, Peter Tugwell, Elizabeth Wager, Margaret Winker, Getu Zhaori

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial

Jona Walk, Isaie J. Reuling, Marije C. Behet, Lisette Meerstein-Kessel, Wouter Graumans, Geert-Jan van Gemert, Rianne Siebelink-Stoter, Marga van de Vegte-Bolmer, Thorsten Janssen, Karina Teelen, Johannes H. W. de Wilt, Quirijn de Mast, André J. van der Ven, Ernest Diez Benavente, Susana Campino, Taane G. Clark, Martijn A. Huynen, Cornelus C. Hermsen, Else M. Bijker, Anja Scholzen, Robert W. Sauerwein

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Borrelia infection and risk of celiac disease

Armin Alaedini, Benjamin Lebwohl, Gary P. Wormser, Peter H. Green, Jonas F. Ludvigsson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A 25-gene classifier predicts overall survival in resectable pancreatic cancer

David J. Birnbaum, Pascal Finetti, Alexia Lopresti, Marine Gilabert, Flora Poizat, Jean-Luc Raoul, Jean-Robert Delpero, Vincent Moutardier, Daniel Birnbaum, Emilie Mamessier, François Bertucci

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Lifestyle precision medicine: the next generation in type 2 diabetes prevention?

Pascal M. Mutie, Giuseppe N. Giordano, Paul W. Franks

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis

Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Anna Norrby-Teglund, Georgios Dimopoulos, Aikaterini Pantazi, Stylianos E. Orfanos, Nikoletta Rovina, Iraklis Tsangaris, Theologia Gkavogianni, Elektra Botsa, Eleftheria Chassiou, Anastasia Kotanidou, Christina Kontouli, Panagiotis Chaloulis, Dimitrios Velissaris, Athina Savva, Jonas-Sundén Cullberg, Karolina Akinosoglou, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis, on behalf of the Hellenic Sepsis Study Group

01.12.2017 | Guideline | Ausgabe 1/2017 Open Access

Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European Union

Jürgen Rehm, Peter Anderson, Jose Angel Arbesu Prieto, Iain Armstrong, Henri-Jean Aubin, Michael Bachmann, Nuria Bastida Bastus, Carlos Brotons, Robyn Burton, Manuel Cardoso, Joan Colom, Daniel Duprez, Gerrit Gmel, Antoni Gual, Ludwig Kraus, Reinhold Kreutz, Helena Liira, Jakob Manthey, Lars Møller, Ľubomír Okruhlica, Michael Roerecke, Emanuele Scafato, Bernd Schulte, Lidia Segura-Garcia, Kevin David Shield, Cristina Sierra, Konstantin Vyshinskiy, Marcin Wojnar, José Zarco

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Is Graves’ disease a primary immunodeficiency? New immunological perspectives on an endocrine disease

Tristan Struja, Alexander Kutz, Stefan Fischli, Christian Meier, Beat Mueller, Mike Recher, Philipp Schuetz

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The risk of type 2 oral polio vaccine use in post-cessation outbreak response

Kevin A. McCarthy, Guillaume Chabot-Couture, Michael Famulare, Hil M. Lyons, Laina D. Mercer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Continental-scale, data-driven predictive assessment of eliminating the vector-borne disease, lymphatic filariasis, in sub-Saharan Africa by 2020

Edwin Michael, Brajendra K. Singh, Benjamin K. Mayala, Morgan E. Smith, Scott Hampton, Jaroslaw Nabrzyski

01.12.2017 | Correspondence | Ausgabe 1/2017 Open Access

Can learning health systems help organisations deliver personalised care?

Bright I. Nwaru, Charles Friedman, John Halamka, Aziz Sheikh

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The cost determinants of routine infant immunization services: a meta-regression analysis of six country studies

Nicolas A. Menzies, Christian Suharlim, Fangli Geng, Zachary J. Ward, Logan Brenzel, Stephen C. Resch

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A randomised trial of the influence of racial stereotype bias on examiners’ scores, feedback and recollections in undergraduate clinical exams

Peter Yeates, Katherine Woolf, Emyr Benbow, Ben Davies, Mairhead Boohan, Kevin Eva

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Spatial model for risk prediction and sub-national prioritization to aid poliovirus eradication in Pakistan

Laina D. Mercer, Rana M. Safdar, Jamal Ahmed, Abdirahman Mahamud, M. Muzaffar Khan, Sue Gerber, Aiden O’Leary, Mike Ryan, Frank Salet, Steve J. Kroiss, Hil Lyons, Alexander Upfill-Brown, Guillaume Chabot-Couture

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

Fiona Macintyre, Yeka Adoke, Alfred B. Tiono, Tran Thanh Duong, Ghyslain Mombo-Ngoma, Marielle Bouyou-Akotet, Halidou Tinto, Quique Bassat, Saadou Issifou, Marc Adamy, Helen Demarest, Stephan Duparc, Didier Leroy, Bart E. Laurijssens, Sophie Biguenet, Afizi Kibuuka, Antoinette Kitoto Tshefu, Melnick Smith, Chanelle Foster, Illse Leipoldt, Peter G. Kremsner, Bui Quang Phuc, Alphonse Ouedraogo, Michael Ramharter, on behalf of the OZ-Piperaquine Study Group

01.12.2017 | Correction | Ausgabe 1/2017 Open Access

Correction to: Gestational hypertensive disorders and retinal microvasculature: the Generation R Study

Laura Benschop, Sarah Schalekamp–Timmermans, Jeanine E. Roeters van Lennep, Vincent W. V. Jaddoe, Tien Yin Wong, Carol Y. Cheung, Eric A. P. Steegers, M. Kamran Ikram

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

Estela Shabani, Benjamin Hanisch, Robert O. Opoka, Thomas Lavstsen, Chandy C. John

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

Jacob Tveiten Bjerrum, Casper Steenholdt, Mark Ainsworth, Ole Haagen Nielsen, Michelle AC Reed, Karen Atkins, Ulrich Leonhard Günther, Fuhua Hao, Yulan Wang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

State of inequality in malaria intervention coverage in sub-Saharan African countries

Katya Galactionova, Thomas A. Smith, Don de Savigny, Melissa A. Penny

01.12.2017 | Debate | Ausgabe 1/2017 Open Access

Voluntary stopping of eating and drinking: is medical support ethically justified?

Ralf J. Jox, Isra Black, Gian Domenico Borasio, Johanna Anneser

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Voluntarily stopping eating and drinking (VSED) to hasten death: may clinicians legally support patients to VSED?

Thaddeus Mason Pope

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Rapid diagnosis of new and relapse tuberculosis by quantification of a circulating antigen in HIV-infected adults in the Greater Houston metropolitan area

Jia Fan, Hedong Zhang, Duc T. Nguyen, Christopher J. Lyon, Charles D. Mitchell, Zhen Zhao, Edward A. Graviss, Ye Hu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Faecal immunochemical tests (FIT) can help to rule out colorectal cancer in patients presenting in primary care with lower abdominal symptoms: a systematic review conducted to inform new NICE DG30 diagnostic guidance

Marie Westwood, Shona Lang, Nigel Armstrong, Sietze van Turenhout, Joaquín Cubiella, Lisa Stirk, Isaac Corro Ramos, Marianne Luyendijk, Remziye Zaim, Jos Kleijnen, Callum G. Fraser

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Is it them or is it us? Unravelling ethnic disparities in undergraduate clinical performance

Karen M. Stegers-Jager

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The potential impact of Brexit and immigration policies on the GP workforce in England: a cross-sectional observational study of GP qualification region and the characteristics of the areas and population they served in September 2016

Aneez Esmail, Maria Panagioti, Evangelos Kontopantelis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Spot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis

Michael E. Murphy, Patrick P. J. Phillips, Carl M. Mendel, Emily Bongard, Anna L. C. Bateson, Robert Hunt, Saraswathi Murthy, Kasha P. Singh, Michael Brown, Angela M. Crook, Andrew J. Nunn, Sarah K. Meredith, Marc Lipman, Timothy D. McHugh, Stephen H. Gillespie, On behalf of the REMoxTB Consortium

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Comparative efficacy and safety of second-line treatments for advanced non-small cell lung cancer with wild-type or unknown status for epidermal growth factor receptor: a systematic review and network meta-analysis

Perrine Créquit, Anna Chaimani, Amélie Yavchitz, Nassima Attiche, Jacques Cadranel, Ludovic Trinquart, Philippe Ravaud

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

Matias C. Vieira, Sara L. White, Nashita Patel, Paul T. Seed, Annette L. Briley, Jane Sandall, Paul Welsh, Naveed Sattar, Scott M. Nelson, Debbie A. Lawlor, Lucilla Poston, Dharmintra Pasupathy, on behalf of the UPBEAT Consortium

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Group-based developmental BMI trajectories, polycystic ovary syndrome, and gestational diabetes: a community-based longitudinal study

Nadira Sultana Kakoly, Arul Earnest, Lisa J. Moran, Helena J. Teede, Anju E. Joham

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Humanitarian and primary healthcare needs of refugee women and children in Afghanistan

Ariel Higgins-Steele, David Lai, Paata Chikvaidze, Khaksar Yousufi, Zelaikha Anwari, Richard Peeperkorn, Karen Edmond

01.12.2017 | Guideline | Ausgabe 1/2017 Open Access

Mapping the evidence on pharmacological interventions for non-affective psychosis in humanitarian non-specialised settings: a UNHCR clinical guidance

Giovanni Ostuzzi, Corrado Barbui, Charlotte Hanlon, Sudipto Chatterjee, Julian Eaton, Lynne Jones, Derrick Silove, Peter Ventevogel

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Individual, collective, and transgenerational traumatization in the Yazidi

Jan Ilhan Kizilhan, Michael Noll-Hussong

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Fluctuations in the incidence of type 1 diabetes in the United States from 2001 to 2015: a longitudinal study

Mary A. M. Rogers, Catherine Kim, Tanima Banerjee, Joyce M. Lee

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Advances and challenges in cirrhosis and portal hypertension

Annalisa Berzigotti

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

An exploration of mortality risk factors in non-severe pneumonia in children using clinical data from Kenya

Timothy Tuti, Ambrose Agweyu, Paul Mwaniki, Niels Peek, Mike English, on behalf of the Clinical Information Network Author Group

01.12.2017 | Guideline | Ausgabe 1/2017 Open Access

DIET@NET: Best Practice Guidelines for dietary assessment in health research

Janet E. Cade, Marisol Warthon-Medina, Salwa Albar, Nisreen A. Alwan, Andrew Ness, Mark Roe, Petra A. Wark, Katharine Greathead, Victoria J. Burley, Paul Finglas, Laura Johnson, Polly Page, Katharine Roberts, Toni Steer, Jozef Hooson, Darren C. Greenwood, Sian Robinson, on behalf of the DIET@NET consortium

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study

Ju-Sheng Zheng, Stephen J. Sharp, Fumiaki Imamura, Albert Koulman, Matthias B. Schulze, Zheng Ye, Jules Griffin, Marcela Guevara, José María Huerta, Janine Kröger, Ivonne Sluijs, Antonio Agudo, Aurelio Barricarte, Heiner Boeing, Sandra Colorado-Yohar, Courtney Dow, Miren Dorronsoro, Pia T. Dinesen, Guy Fagherazzi, Paul W. Franks, Edith J. M. Feskens, Tilman Kühn, Verena Andrea Katzke, Timothy J. Key, Kay-Tee Khaw, Maria Santucci de Magistris, Francesca Romana Mancini, Elena Molina-Portillo, Peter M. Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, Jose Ramón Quirós, Olov Rolandsson, Fulvio Ricceri, Annemieke M. W. Spijkerman, Nadia Slimani, Giovanna Tagliabue, Anne Tjonneland, Rosario Tumino, Yvonne T. van der Schouw, Claudia Langenberg, Elio Riboli, Nita G. Forouhi, Nicholas J. Wareham

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effectiveness of direct-acting antiviral therapy for hepatitis C in difficult-to-treat patients in a safety-net health system: a retrospective cohort study

Christina Yek, Carolina de la Flor, John Marshall, Cindy Zoellner, Grace Thompson, Lisa Quirk, Christian Mayorga, Barbara J. Turner, Amit G. Singal, Mamta K. Jain

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Telomere tracking from birth to adulthood and residential traffic exposure

Esmée M. Bijnens, Maurice P. Zeegers, Catherine Derom, Dries S. Martens, Marij Gielen, Geja J. Hageman, Michelle Plusquin, Evert Thiery, Robert Vlietinck, Tim S. Nawrot

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso

Loretta Brabin, Stephen A. Roberts, Sabine Gies, Andrew Nelson, Salou Diallo, Christopher J. Stewart, Adama Kazienga, Julia Birtles, Sayouba Ouedraogo, Yves Claeys, Halidou Tinto, Umberto d’Alessandro, E. Brian Faragher, Bernard Brabin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens

Patrick P. J. Phillips, Carl M. Mendel, Andrew J. Nunn, Timothy D. McHugh, Angela M. Crook, Robert Hunt, Anna Bateson, Stephen H. Gillespie

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities in the United States

José L. Peñalvo, Frederick Cudhea, Renata Micha, Colin D. Rehm, Ashkan Afshin, Laurie Whitsel, Parke Wilde, Tom Gaziano, Jonathan Pearson-Stuttard, Martin O’Flaherty, Simon Capewell, Dariush Mozaffarian

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Depression comorbid with tuberculosis and its impact on health status: cross-sectional analysis of community-based data from 48 low- and middle-income countries

Ai Koyanagi, Davy Vancampfort, André F. Carvalho, Jordan E. DeVylder, Josep Maria Haro, Damiano Pizzol, Nicola Veronese, Brendon Stubbs

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals

Maik Pietzner, Anne Kaul, Ann-Kristin Henning, Gabi Kastenmüller, Anna Artati, Markus M. Lerch, Jerzy Adamski, Matthias Nauck, Nele Friedrich

01.12.2017 | Technical advance | Ausgabe 1/2017 Open Access

Choice of surrogate tissue influences neonatal EWAS findings

Xinyi Lin, Ai Ling Teh, Li Chen, Ives Yubin Lim, Pei Fang Tan, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Yung Seng Lee, Joanna D. Holbrook, Keith M. Godfrey, Michael J. Meaney, Michael S. Kobor, Yap Seng Chong, Peter D. Gluckman, Neerja Karnani

01.12.2017 | Correction | Ausgabe 1/2017 Open Access

Correction to: An exploration of mortality risk factors in non-severe pneumonia in children using clinical data from Kenya

Timothy Tuti, Ambrose Agweyu, Paul Mwaniki, Niels Peek, Mike English, on behalf of the Clinical Information Network Author Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Spectrum of mutations in monogenic diabetes genes identified from high-throughput DNA sequencing of 6888 individuals

Vikas Bansal, Johann Gassenhuber, Tierney Phillips, Glenn Oliveira, Rebecca Harbaugh, Nikki Villarasa, Eric J. Topol, Thomas Seufferlein, Bernhard O. Boehm

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

Seungyeul Yoo, Wenhui Wang, Qin Wang, M Isabel Fiel, Eunjee Lee, Spiros P. Hiotis, Jun Zhu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule

Judith Verduijn, Josine E. Verhoeven, Yuri Milaneschi, Robert A. Schoevers, Albert M. van Hemert, Aartjan T. F. Beekman, Brenda W. J. H. Penninx

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The extra cost of comorbidity: multiple illnesses and the economic burden of non-communicable diseases

Sébastien Cortaredona, Bruno Ventelou

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Modeling HIV-HCV coinfection epidemiology in the direct-acting antiviral era: the road to elimination

Victor Virlogeux, Fabien Zoulim, Pascal Pugliese, Isabelle Poizot-Martin, Marc-Antoine Valantin, Lise Cuzin, Jacques Reynes, Eric Billaud, Thomas Huleux, Firouze Bani-Sadr, David Rey, Anne Frésard, Christine Jacomet, Claudine Duvivier, Antoine Cheret, Laurent Hustache-Mathieu, Bruno Hoen, André Cabié, Laurent Cotte, the Dat’AIDS Study Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Blood lipids and lipoproteins in relation to incidence and mortality risks for CVD and cancer in the prospective EPIC–Heidelberg cohort

Verena Andrea Katzke, Disorn Sookthai, Theron Johnson, Tilman Kühn, Rudolf Kaaks

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Bringing patient-centered tuberculosis diagnosis into the light of day

J. Lucian Davis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Factors associated with junior doctors’ decisions to apply for general practice training programmes in the UK: secondary analysis of data from the UKMED project

Thomas C. E. Gale, Paul J. Lambe, Martin J. Roberts

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Models and analyses to understand threats to polio eradication

James S. Koopman

01.12.2017 | Debate | Ausgabe 1/2017 Open Access

Advice and care for patients who die by voluntarily stopping eating and drinking is not assisted suicide

Andrew McGee, Franklin G. Miller

01.12.2017 | Opinion | Ausgabe 1/2017 Open Access

Simulations for designing and interpreting intervention trials in infectious diseases

M. Elizabeth Halloran, Kari Auranen, Sarah Baird, Nicole E. Basta, Steven E. Bellan, Ron Brookmeyer, Ben S. Cooper, Victor DeGruttola, James P. Hughes, Justin Lessler, Eric T. Lofgren, Ira M. Longini, Jukka-Pekka Onnela, Berk Özler, George R. Seage, Thomas A. Smith, Alessandro Vespignani, Emilia Vynnycky, Marc Lipsitch

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