01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Real-world effectiveness of abatacept for rheumatoid arthritis treatment in European and Canadian populations: a 6-month interim analysis of the 2-year, observational, prospective ACTION study
Hubert G Nüßlein, Rieke Alten, Mauro Galeazzi, Hanns-Martin Lorenz, Dimitrios Boumpas, Michael T Nurmohamed, William G Bensen, Gerd R Burmester, Hans-Hartmut Peter, Franz Rainer, Karel Pavelka, Melanie Chartier, Coralie Poncet, Christiane Rauch, Manuela Le Bars
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
HUMeral Shaft Fractures: MEasuring Recovery after Operative versus Non-operative Treatment (HUMMER): a multicenter comparative observational study
Kiran C Mahabier, Esther MM Van Lieshout, Hugo W Bolhuis, P Koen Bos, Maarten WGA Bronkhorst, Milko MM Bruijninckx, Jeroen De Haan, Axel R Deenik, Boudewijn J Dwars, Martin G Eversdijk, J Carel Goslings, Robert Haverlag, Martin J Heetveld, Albert JH Kerver, Karel A Kolkman, Peter A Leenhouts, Sven AG Meylaerts, Ron Onstenk, Martijn Poeze, Rudolf W Poolman, Bas J Punt, W Herbert Roerdink, Gert R Roukema, Jan Bernard Sintenie, Nicolaj MR Soesman, Andras KF Tanka, Edgar JT Ten Holder, Maarten Van der Elst, Frank HWM Van der Heijden, Frits M Van der Linden, Peer Van der Zwaal, Jan P Van Dijk, Hans-Peter W Van Jonbergen, Egbert JMM Verleisdonk, Jos PAM Vroemen, Marco Waleboer, Philippe Wittich, Wietse P Zuidema, Suzanne Polinder, Michael HJ Verhofstad, Dennis Den Hartog
01.12.2014 | Technical advance | Ausgabe 1/2014
Open Access
Posterior short segment pedicle screw fixation and TLIF for the treatment of unstable thoracolumbar/lumbar fracture
Ling Wang, Jianjun Li, Hong Wang, Qun Yang, Decheng Lv, Weiguo Zhang, Kai Tang, Limin Shang, Changming Jiang, Chunming Wu, Kai Ma, Bo Wang, Yang Liu, Rui Zhang, Xianping Shang, Depeng Kou, Xunyuan Jia, Xianglong Yang, Yilong Tang, Meng Zhang, Pengrui Wang, Yan Xu, Shijin Wang
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Efficacy of MRI in primary care for patients with knee complaints due to trauma: protocol of a randomised controlled non-inferiority trial (TACKLE trial)
Nynke M Swart, Kim van Oudenaarde, Paul R Algra, Partick JE Bindels, Wilbert B van den Hout, Bart W Koes, Rob GHH Nelissen, Jan AN Verhaar, Hans JL Bloem, Sita MA Bierma-Zeinstra, Monique Reijnierse, Pim AJ Luijsterburg
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Advantages of a combined rheumatoid arthritis magnetic resonance imaging score (RAMRIS) for hand and feet: does the RAMRIS of the hand alone underestimate disease activity and progression?
Philipp Sewerin, Christian Buchbender, Stefan Vordenbäumen, Axel Scherer, Falk Miese, Ralph Brinks, Hans-Joerg Wittsack, Sabine Klein, Matthias Schneider, Gerald Antoch, Benedikt Ostendorf
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Maintained physical activity and physiotherapy in the management of distal upper limb pain – a protocol for a randomised controlled trial (the arm pain trial)
Gareth T Jones, Kathrin Mertens, Gary J Macfarlane, Keith T Palmer, David Coggon, Karen Walker-Bone, Kim Burton, Peter J Heine, Candy McCabe, Paul McNamee, Alex McConnachie
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
The IFITM5 mutation c.-14C > T results in an elongated transcript expressed in human bone; and causes varying phenotypic severity of osteogenesis imperfecta type V
Syndia Lazarus, Aideen M McInerney-Leo, Fiona A McKenzie, Gareth Baynam, Stephanie Broley, Barbra V Cavan, Craig F Munns, Johannes Egbertus Hans Pruijs, David Sillence, Paulien A Terhal, Karena Pryce, Matthew A Brown, Andreas Zankl, Gethin Thomas, Emma L Duncan
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Patterns and predictors of osteoporosis medication discontinuation and switching among Medicare beneficiaries
Huifeng Yun, Jeffrey R Curtis, Lingli Guo, Meredith Kilgore, Paul Muntner, Kenneth Saag, Robert Matthews, Michael Morrisey, Nicole C Wright, David J Becker, Elizabeth Delzell
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Surgery versus conservative treatment in patients with type A distal radius fractures, a randomized controlled trial
Monique MJ Walenkamp, J Carel Goslings, Annechien Beumer, Robert Haverlag, Peter A Leenhouts, Egbert JMM Verleisdonk, Ronald SL Liem, Jan Bernard Sintenie, Maarten WGA Bronkhorst, Jasper Winkelhagen, Niels WL Schep
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Back pain in seniors: the Back pain Outcomes using Longitudinal Data (BOLD) cohort baseline data
Jeffrey G Jarvik, Bryan A Comstock, Patrick J Heagerty, Judith A Turner, Sean D Sullivan, Xu Shi, David R Nerenz, Srdjan S Nedeljkovic, Larry Kessler, Kathryn James, Janna L Friedly, Brian W Bresnahan, Zoya Bauer, Andrew L Avins, Richard A Deyo
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Validation of quantitative magnetic resonance imaging-based apparent bone volume fraction in peri-articular tibial bone of cadaveric knees
Jeffrey B Driban, Mary F Barbe, Mamta Amin, Neil S Kalariya, Ming Zhang, Grace H Lo, Anna M Tassinari, Daniel Harper, Lori Lyn Price, Charles B Eaton, Erika Schneider, Timothy E McAlindon
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
CASINO: Surgical or Nonsurgical Treatment for cervical radiculopathy, a randomised controlled trial
Sarita van Geest, Barbara Kuijper, Marinus Oterdoom, Wilbert van den Hout, Ronald Brand, Theo Stijnen, Pim Assendelft, Bart Koes, Wilco Jacobs, Wilco Peul, Carmen Vleggeert-Lankamp
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Clinical factors affecting pathological fracture and healing of unicameral bone cysts
Hiroshi Urakawa, Satoshi Tsukushi, Kozo Hosono, Hideshi Sugiura, Kenji Yamada, Yoshihisa Yamada, Eiji Kozawa, Eisuke Arai, Naohisa Futamura, Naoki Ishiguro, Yoshihiro Nishida
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
A randomized controlled trial of nonoperative treatment versus open reduction and internal fixation for stable, displaced, partial articular fractures of the radial head: the RAMBO trial
Wendy E Bruinsma, Izaäk F Kodde, Robert-Jan O de Muinck Keizer, Peter Kloen, Anneluuk LC Lindenhovius, Jos PAM Vroemen, Robert Haverlag, Michel PJ van den Bekerom, Hugo W Bolhuis, Pieter HJ Bullens, Sven AG Meylaerts, Peer van der Zwaal, E Philip Steller, Michiel Hageman, David C Ring, Dennis den Hartog, Eric R Hammacher, Graham JW King, George S Athwal, Kenneth J Faber, Darren Drosdowech, Ruby Grewal, J Carel Goslings, Niels WL Schep, Denise Eygendaal
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Evaluation of a structured goal planning and tailored follow-up programme in rehabilitation for patients with rheumatic diseases: protocol for a pragmatic, stepped-wedge cluster randomized trial
Ingvild Kjeken, Gunnhild Berdal, Ingvild Bø, Turid Dager, Anne Dingsør, Jon Hagfors, Bente Hamnes, Siv G Eppeland, Elin Fjerstad, Petter Mowinckel, Merete Nielsen, Randi W Rørstad, Anne-Lene Sand-Svartrud, Bente Slungaard, Sigrid H Wigers, Kåre Birger Hagen
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
An administrative data validation study of the accuracy of algorithms for identifying rheumatoid arthritis: the influence of the reference standard on algorithm performance
Jessica Widdifield, Claire Bombardier, Sasha Bernatsky, J Michael Paterson, Diane Green, Jacqueline Young, Noah Ivers, Debra A Butt, R Liisa Jaakkimainen, J Carter Thorne, Karen Tu
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
The Patella Pro study — effect of a knee brace on patellofemoral pain syndrome: design of a randomized clinical trial (DRKS-ID:DRKS00003291)
Wolf Petersen, Andree Ellermann, Ingo Volker Rembitzki, Sven Scheffler, Mirco Herbort, Frederike Sophie Sprenker, Andrea Achtnich, Gert Peter Brüggemann, Raymond Best, Frank Hoffmann, Andreas Gösele Koppenburg, Christian Liebau
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Correlation of lateral stenosis in MRI with symptoms, walking capacity and EMG findings in patients with surgically confirmed lateral lumbar spinal canal stenosis
Pekka Kuittinen, Petri Sipola, Timo Juhani Aalto, Sara Määttä, Anita Parviainen, Tapani Saari, Sanna Sinikallio, Sakari Savolainen, Veli Turunen, Heikki Kröger, Olavi Airaksinen, Ville Leinonen
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669)
Annette Bishop, Gwenllian Wynne-Jones, Sarah A Lawton, Danielle van der Windt, Chris Main, Gail Sowden, A Kim Burton, Martyn Lewis, Sue Jowett, Tom Sanders, Elaine M Hay, Nadine E Foster
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Vitamin D status in non-supplemented postmenopausal Taiwanese women with osteoporosis and fragility fracture
Jawl-Shan Hwang, Keh-Sung Tsai, Yuh-Min Cheng, Wen-Jer Chen, Shih-Te Tu, Ko-Hsiu Lu, Sheng-Mou Hou, Shu-Hua Yang, Henrich Cheng, Hung Jen Lai, Sharon Lei, Jung-Fu Chen
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563)
Nadine E Foster, Emma L Healey, Melanie A Holden, Elaine Nicholls, David GT Whitehurst, Susan Jowett, Clare Jinks, Edward Roddy, Elaine M Hay
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Internet-mediated physiotherapy and pain coping skills training for people with persistent knee pain (IMPACT – knee pain): a randomised controlled trial protocol
Fiona Dobson, Rana S Hinman, Simon French, Christine Rini, Francis Keefe, Rachel Nelligan, J Haxby Abbott, Christina Bryant, Margaret P Staples, Andrew Dalwood, Kim L Bennell
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Prediction of trapezius muscle activity and shoulder, head, neck, and torso postures during computer use: results of a field study
Jennifer L Bruno Garza, Belinda HW Eijckelhof, Maaike A Huysmans, Peter W Johnson, Jaap H van Dieen, Paul J Catalano, Jeffrey N Katz, Allard J van der Beek, Jack T Dennerlein
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Evaluation of efficacy of a new hybrid fusion device: a randomized, two-centre controlled trial
Jan Siewe, Jan Bredow, Johannes Oppermann, Timmo Koy, Stefan Delank, Peter Knoell, Peer Eysel, Rolf Sobottke, Kourosh Zarghooni, Marc Röllinghoff
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization
Roland Blanqué, Liên Lepescheux, Marielle Auberval, Dominique Minet, Didier Merciris, Céline Cottereaux, Philippe Clément-Lacroix, Philippe Delerive, Florence Namour
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation
Yi He, Anne Sofie Siebuhr, Niels Ulrik Brandt-Hansen, Jianxia Wang, Di Su, Qinlong Zheng, Ole Simonsen, Kristian Kjær Petersen, Lars Arendt-Nielsen, Thomas Eskehave, Hans Christian Hoeck, Morten Asser Karsdal, Anne C Bay-Jensen
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
A comparative effectiveness trial of postoperative management for lumbar spine surgery: changing behavior through physical therapy (CBPT) study protocol
Kristin R Archer, Rogelio A Coronado, Christine M Haug, Susan W Vanston, Clinton J Devin, Christopher J Fonnesbeck, Oran S Aaronson, Joseph S Cheng, Richard L Skolasky, Lee H Riley III, Stephen T Wegener
01.12.2014 | Case report | Ausgabe 1/2014
Open Access
Metal hypersensitivity in patient with posterior lumbar spine fusion: a case report and its literature review
Xianping Shang, Ling Wang, Depeng Kou, Xunyuan Jia, Xianglong Yang, Meng Zhang, Yilong Tang, Pengrui Wang, Shijin Wang, Yan Xu, Hong Wang
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Sex-related differences in the association between waist circumference and bone mineral density in a Korean population
Lian-Hua Cui, Min-Ho Shin, Sun-Seog Kweon, Jin-Su Choi, Jung-Ae Rhee, Young-Hoon Lee, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park, So-Yeon Ryu, Seong-Woo Choi
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
In vivo experimental intervertebral disc degeneration induced by bleomycin in the rhesus monkey
Fuxin Wei, Rui Zhong, Zhiyu Zhou, Le Wang, Ximin Pan, Shangbin Cui, Xuenong Zou, Manman Gao, Haixing Sun, Wenfang Chen, Shaoyu Liu
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Associations between socioeconomic status and primary total knee joint replacements performed for osteoarthritis across Australia 2003–10: data from the Australian Orthopaedic Association National Joint Replacement Registry
Sharon L Brennan, Stephen E Lane, Michelle Lorimer, Rachelle Buchbinder, Anita E Wluka, Richard S Page, Richard H Osborne, Julie A Pasco, Kerrie M Sanders, Kara Cashman, Peter R Ebeling, Stephen E Graves
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Primum non nocere: shared informed decision making in low back pain – a pilot cluster randomised trial
Shilpa Patel, Anne Ngunjiri, Siew Wan Hee, Yaling Yang, Sally Brown, Tim Friede, Frances Griffiths, Joanne Lord, Harbinder Sandhu, Jill Thistlethwaite, Colin Tysall, Martin Underwood
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, phase III, non-inferiority clinical trial
In Ah Choi, Han-Joo Baek, Chul-Soo Cho, Yeon-Ah Lee, Won Tae Chung, Young Eun Park, Yun Jong Lee, Yong-Beom Park, Jisoo Lee, Shin-Seok Lee, Wan-Hee Yoo, Jung-Soo Song, Seong Wook Kang, Hyun Ah Kim, Yeong Wook Song
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Clinic variation in recruitment metrics, patient characteristics and treatment use in a randomized clinical trial of osteoarthritis management
Kelli D Allen, Hayden B Bosworth, Ranee Chatterjee, Cynthia J Coffman, Leonor Corsino, Amy S Jeffreys, Eugene Z Oddone, Catherine Stanwyck, William S Yancy Jr, Rowena J Dolor
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Fostering autonomous motivation, physical activity and cardiorespiratory fitness in rheumatoid arthritis: protocol and rationale for a randomised control trial
Peter C Rouse, Jet JCS Veldhuijzen Van Zanten, George S Metsios, Nikos Ntoumanis, Chen-an Yu, Yiannis Koutedakis, Sally AM Fenton, Joanna Coast, Hema Mistry, George D Kitas, Joan L Duda
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis
Kalyan Chakravarthy, Robert Faltus, Gain Robinson, Raquel Sevilla, John Shin, Mark Zielstorff, Alan Byford, Erica Leccese, Michael J Caniga, SuChun Hseih, Shuli Zhang, Chi-Sung Chiu, Jie Zhang-Hoover, Lily Y Moy, Robbie L McLeod, Dana Stoffregen, Weisheng Zhang, Anwar Murtaza, Milenko Cicmil
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
The TRACTISS Protocol: a randomised double blind placebo controlled clinical TRial of Anti-B-Cell Therapy In patients with primary Sjögren’s Syndrome
Sarah Brown, Nuria Navarro Coy, Costantino Pitzalis, Paul Emery, Sue Pavitt, Janine Gray, Claire Hulme, Frances Hall, Robert Busch, Pete Smith, Luke Dawson, Michele Bombardieri, Ng Wan-fai, Colin Pease, Elizabeth Price, Nurhan Sutcliffe, Clodagh Woods, Sharon Ruddock, Colin Everett, Catherine Reynolds, Emma Skinner, Ana Poveda-Gallego, John Rout, Iain Macleod, Saaeha Rauz, Simon Bowman, TRACTISS trial team
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Comparison of orthopaedic manifestations of multiple epiphyseal dysplasia caused by MATN3 versus COMP mutations: a case control study
Sang Gyo Seo, Hae-Ryong Song, Hyun Woo Kim, Won Joon Yoo, Jong Sup Shim, Chin Youb Chung, Moon Seok Park, Chang-Wug Oh, Changhoon Jeong, Kwang Soon Song, Ok-Hwa Kim, Sung Sup Park, In Ho Choi, Tae-Joon Cho
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Unexpected angular or rotational deformity after corrective osteotomy
Seung Yeol Lee, Jiwon Jeong, Kyungho Lee, Chin Youb Chung, Kyoung Min Lee, Soon-Sun Kwon, Young Choi, Tae Gyun Kim, Jeong Ik Lee, Jehee Lee, Moon Seok Park
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Self-perceived weather sensitivity and joint pain in older people with osteoarthritis in six European countries: results from the European Project on OSteoArthritis (EPOSA)
Erik J Timmermans, Suzan van der Pas, Laura A Schaap, Mercedes Sánchez-Martínez, Sabina Zambon, Richard Peter, Nancy L Pedersen, Elaine M Dennison, Michael Denkinger, Maria Victoria Castell, Paola Siviero, Florian Herbolsheimer, Mark H Edwards, Ángel Otero, Dorly JH Deeg
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Ankle Injury Management (AIM): design of a pragmatic multi-centre equivalence randomised controlled trial comparing Close Contact Casting (CCC) to Open surgical Reduction and Internal Fixation (ORIF) in the treatment of unstable ankle fractures in patients over 60 years
Keith Willett, David J Keene, Lesley Morgan, Bridget Gray, Robert Handley, Tim Chesser, Ian Pallister, Elizabeth Tutton, Christopher Knox, Ranjit Lall, Andrew Briggs, Sarah E Lamb
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
The 'Switch’ study protocol: a randomised-controlled trial of switching to an alternative tumour-necrosis factor (TNF)-inhibitor drug or abatacept or rituximab in patients with rheumatoid arthritis who have failed an initial TNF-inhibitor drug
Nuria C Navarro Coy, Sarah Brown, Ailsa Bosworth, Claire T Davies, Paul Emery, Colin C Everett, Catherine Fernandez, Janine C Gray, Suzanne Hartley, Claire Hulme, Anne-Maree Keenan, Christopher McCabe, Anthony Redmond, Catherine Reynolds, David Scott, Linda D Sharples, Sue Pavitt, Maya H Buch
