01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Determinants of arterial stiffness in COPD
Surya P Bhatt, Adam G Cole, James Michael Wells, Hrudaya Nath, Jubal R Watts, John R Cockcroft, Mark T Dransfield
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation
Joan P Blonder, Sarah C Mutka, Xicheng Sun, Jian Qiu, Lucia H Green, Navdeep K Mehra, Ramakrishna Boyanapalli, Michael Suniga, Kirsten Look, Chris Delany, Jane P Richards, Doug Looker, Charles Scoggin, Gary J Rosenthal
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
A blinded evaluation of the efficacy and safety of glycopyrronium, a once-daily long-acting muscarinic antagonist, versus tiotropium, in patients with COPD: the GLOW5 study
Kenneth R Chapman, Kai-Michael Beeh, Jutta Beier, Eric D Bateman, Anthony D’Urzo, Robert Nutbrown, Michelle Henley, Hungta Chen, Tim Overend, Peter D’Andrea
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
A comparison of muscle strength and endurance, exercise capacity, fatigue perception and quality of life in patients with chronic obstructive pulmonary disease and healthy subjects: a cross-sectional study
Ebru Calik-Kutukcu, Sema Savci, Melda Saglam, Naciye Vardar-Yagli, Deniz Inal-Ince, Hulya Arikan, Zeynep Aribas, Ozge Ozer, Meral Bosnak-Guclu, Lutfi Coplu
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Quality of life is associated with physical activity and fitness in cystic fibrosis
Helge Hebestreit, Kerstin Schmid, Stephanie Kieser, Sibylle Junge, Manfred Ballmann, Kristina Roth, Alexandra Hebestreit, Thomas Schenk, Christian Schindler, Hans-Georg Posselt, Susi Kriemler
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Taking Healthy Steps: rationale, design and baseline characteristics of a randomized trial of a pedometer-based internet-mediated walking program in veterans with chronic obstructive pulmonary disease
Carlos H Martinez, Marilyn L Moy, Huong Q Nguyen, Miriam Cohen, Reema Kadri, Pia Roman, Robert G Holleman, Hyungjin Myra Kim, David E Goodrich, Nicholas D Giardino, Caroline R Richardson
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Secondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan
Haruyuki Ishii, John F Seymour, Ryushi Tazawa, Yoshikazu Inoue, Naoyuki Uchida, Aya Nishida, Yoshihito Kogure, Takeshi Saraya, Keisuke Tomii, Toshinori Takada, Yuko Itoh, Masayuki Hojo, Toshio Ichiwata, Hajime Goto, Koh Nakata
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Extrafine Beclomethasone/formoterol compared to Fluticasone/salmeterol Combination Therapy in COPD
Dave Singh, Gabriele Nicolini, Eddi Bindi, Massimo Corradi, Daniele Guastalla, Jorg Kampschulte, Władysław Pierzchała, Abdullah Sayiner, Mária Szilasi, Claudio Terzano, Jørgen Vestbo
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-γ for the evaluation of pleural tuberculosis: a prospective cohort study
Richard Meldau, Jonny Peter, Grant Theron, Greg Calligaro, Brian Allwood, Greg Symons, Hoosain Khalfey, Gina Ntombenhle, Ureshnie Govender, Anke Binder, Richard van Zyl-Smit, Keertan Dheda
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial
Timm Greulich, Christoph Nell, Janine Koepke, Juliane Fechtel, Maja Franke, Bernd Schmeck, Daniel Haid, Sandra Apelt, Silke Filipovic, Klaus Kenn, Sabina Janciauskiene, Claus Vogelmeier, Andreas Rembert Koczulla
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia
Tomoyuki Kakugawa, Shin-ichi Yokota, Yuji Ishimatsu, Tomayoshi Hayashi, Shota Nakashima, Shintaro Hara, Noriho Sakamoto, Hiroshi Kubota, Mariko Mine, Yasuhiro Matsuoka, Hiroshi Mukae, Kazuhiro Nagata, Shigeru Kohno
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Longterm follow-up in European respiratory health studies – patterns and implications
Ane Johannessen, Giuseppe Verlato, Bryndis Benediktsdottir, Bertil Forsberg, Karl Franklin, Thorarinn Gislason, Mathias Holm, Christer Janson, Rain Jögi, Eva Lindberg, Ferenc Macsali, Ernst Omenaas, Francisco Gomez Real, Eirunn Waatevik Saure, Vivi Schlünssen, Torben Sigsgaard, Trude Duelien Skorge, Cecilie Svanes, Kjell Torén, Marie Waatevik, Roy Miodini Nilsen, Roberto de Marco
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts
Matthew R Gingo, Goundappa K Balasubramani, Thomas B Rice, Lawrence Kingsley, Eric C Kleerup, Roger Detels, Eric C Seaberg, Ruth M Greenblatt, Susan Holman, Laurence Huang, Sarah H Sutton, Marnie Bertolet, Alison Morris
01.12.2014 | Case report | Ausgabe 1/2014
Open Access
Alveolar epithelial cells undergo epithelial-mesenchymal transition in acute interstitial pneumonia: a case report
Hongbo Li, Jinjin Zhang, Xiaodong Song, Tao Wang, Zhi Li, Dong Hao, Xiaozhi Wang, Qingyin Zheng, Cuiping Mao, Pan Xu, Changjun Lv
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Exacerbations in patients with chronic obstructive pulmonary disease receiving physical therapy: a cohort-nested randomised controlled trial
Emmylou Beekman, Ilse Mesters, Erik JM Hendriks, Jean WM Muris, Geertjan Wesseling, Silvia MAA Evers, Guus M Asijee, Annemieke Fastenau, Hannah N Hoffenkamp, Rik Gosselink, Onno CP van Schayck, Rob A de Bie
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Dynamics of soluble and cellular inflammatory markers in nasal lavage obtained from Cystic Fibrosis patients during intravenous antibiotic treatment
Julia Hentschel, Manuela Jäger, Natalie Beiersdorf, Nele Fischer, Franziska Doht, Ruth K Michl, Thomas Lehmann, Udo R Markert, Klas Böer, Peter M Keller, Mathias W Pletz, Jochen G Mainz
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia
Olaf Eickmeier, Su Youn Kim, Eva Herrmann, Constanze Döring, Ruth Duecker, Sandra Voss, Sibylle Wehner, Christoph Hölscher, Julia Pietzner, Stefan Zielen, Ralf Schubert
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
The Cohort for Childhood Origin of Asthma and allergic diseases (COCOA) study: design, rationale and methods
Hyeon-Jong Yang, So-Yeon Lee, Dong In Suh, Youn Ho Shin, Byoung-Ju Kim, Ju-Hee Seo, Hyoung Yoon Chang, Kyung Won Kim, Kangmo Ahn, Yee-Jin Shin, Kyung-Sook Lee, Cheol Min Lee, Se-Young Oh, Ho Kim, Jong-Han Leem, Hwan-Cheol Kim, Eun-Jin Kim, Joo-Shil Lee, Soo-Jong Hong
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
An autopsy study of combined pulmonary fibrosis and emphysema: correlations among clinical, radiological, and pathological features
Minoru Inomata, Soichiro Ikushima, Nobuyasu Awano, Keisuke Kondoh, Kohta Satake, Masahiro Masuo, Yuji Kusunoki, Atsuko Moriya, Hiroyuki Kamiya, Tsunehiro Ando, Noriyo Yanagawa, Toshio Kumasaka, Takashi Ogura, Fumikazu Sakai, Arata Azuma, Akihiko Gemma, Tamiko Takemura
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Effects of sex hormones on bronchial reactivity during the menstrual cycle
Maria Matteis, Francesca Polverino, Giuseppe Spaziano, Fiorentina Roviezzo, Carlo Santoriello, Nikol Sullo, Maria Rosaria Bucci, Francesco Rossi, Mario Polverino, Caroline A Owen, Bruno D’Agostino
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Epigenetics modifications and Subclinical Atherosclerosis in Obstructive Sleep Apnea: The EPIOSA study
Jose M Marin, Jorge Artal, Teresa Martin, Santiago J Carrizo, Marta Andres, Inmaculada Martin-Burriel, Rosa Bolea, Arianne Sanz, Luis Varona, Javier Godino, Begoña Gallego, Jose A Garcia-Erce, Isabel Villar, Victoria Gil, Marta Forner, Jose P Cubero, Luis Ros
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Randomized study of the safety, pharmacokinetics, and bronchodilatory efficacy of a proprietary glycopyrronium metered-dose inhaler in study patients with chronic obstructive pulmonary disease
Stephen Rennard, Charles Fogarty, Colin Reisner, Carlos Fernandez, Tracy Fischer, Michael Golden, Earl St Rose, Patrick Darken, Gregory Tardie, Chadwick Orevillo
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Lung fibrotic tenascin-C upregulation is associated with other extracellular matrix proteins and induced by TGFβ1
Susanna Estany, Vanesa Vicens-Zygmunt, Roger Llatjós, Ana Montes, Rosa Penín, Ignacio Escobar, Antoni Xaubet, Salud Santos, Frederic Manresa, Jordi Dorca, Maria Molina-Molina
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Impact of air pollution on respiratory diseases in children with recurrent wheezing or asthma
Susanna Esposito, Carlotta Galeone, Mara Lelii, Benedetta Longhi, Beatrice Ascolese, Laura Senatore, Elisabetta Prada, Valentina Montinaro, Stefano Malerba, Maria Francesca Patria, Nicola Principi
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Effectiveness of the Assessment of Burden of Chronic Obstructive Pulmonary Disease (ABC) tool: study protocol of a cluster randomised trial in primary and secondary care
Annerika HM Slok, Johannes CCM in ’t Veen, Niels H Chavannes, Thys van der Molen, Maureen PMH Rutten-van Mölken, Huib AM Kerstjens, Guus M Asijee, Philippe L Salomé, Sebastiaan Holverda, Richard PN Dekhuijzen, Denise Schuiten, Gerard van Breukelen, Daniel Kotz, Onno CP van Schayck
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
A symptom-related monitoring program following pulmonary embolism for the early detection of CTEPH: a prospective observational registry study
Matthias Held, Alexander Hesse, Franziska Gött, Regina Holl, Gudrun Hübner, Philipp Kolb, Heinz Jakob Langen, Tobias Romen, Franziska Walter, Hans Joachim Schäfers, Heinrike Wilkens, Berthold Jany
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: a pilot study
Chun-Hua Wang, Pai-Chien Chou, Wen-Ching Joa, Li-Fei Chen, Te-Fang Sheng, Shu-Chuan Ho, Horng-Chyuan Lin, Chien-Da Huang, Fu-Tsai Chung, Kian Fan Chung, Han-Pin Kuo
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Indoor pollutant exposure is associated with heightened respiratory symptoms in atopic compared to non-atopic individuals with COPD
Deepak A Kaji, Andrew J Belli, Meredith C McCormack, Elizabeth C Matsui, D’Ann L Williams, Laura Paulin, Nirupama Putcha, Roger D Peng, Gregory B Diette, Patrick N Breysse, Nadia N Hansel
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
The effect of perinatal anxiety on bronchiolitis is influenced by polymorphisms in ROS-related genes
Eun Lee, Hyoung Yoon Chang, Kyung-Sook Lee, Dong In Suh, Ho-Sung Yu, Mi-Jin Kang, In Ae Choi, Jinah Park, Kyung Won Kim, Youn Ho Shin, Kang Mo Ahn, Ja-Young Kwon, Suk-Joo Choi, Kyung-Ju Lee, Hye-Sung Won, Song I Yang, Young-Ho Jung, Hyung Young Kim, Ju-Hee Seo, Ji-Won Kwon, Byoung-Ju Kim, Hyo-Bin Kim, So-Yeon Lee, Eun-Jin Kim, Joo-Shil Lee, Katherine M Keyes, Yee-Jin Shin, Soo-Jong Hong, the COCOA study group
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus
Craig P Hersh, Barry J Make, David A Lynch, R Graham Barr, Russell P Bowler, Peter MA Calverley, Peter J Castaldi, Michael H Cho, Harvey O Coxson, Dawn L DeMeo, Marilyn G Foreman, MeiLan K Han, Benjamin J Harshfield, John E Hokanson, Sharon Lutz, Joe W Ramsdell, Elizabeth A Regan, Stephen I Rennard, Joyce D Schroeder, Frank C Sciurba, Robert M Steiner, Ruth Tal-Singer, Edwin JR van Beek, Edwin K Silverman, James D Crapo, the COPDGene and ECLIPSE Investigators
01.12.2014 | Case report | Ausgabe 1/2014
Open Access
Development of microscopic polyangiitis-related pulmonary fibrosis in a patient with autoimmune pulmonary alveolar proteinosis
Yuhei Kinehara, Hiroshi Kida, Yoshikazu Inoue, Masaki Hirose, Akihiko Nakabayashi, Yoshiko Takeuchi, Yoshitomo Hayama, Kiyoharu Fukushima, Haruhiko Hirata, Koji Inoue, Toshiyuki Minami, Izumi Nagatomo, Yoshito Takeda, Toshiki Funakoshi, Takashi Kijima, Atsushi Kumanogoh
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
Protocol for a mixed-methods study of supplemental oxygen in pulmonary fibrosis
Amanda Belkin, Kaitlin Fier, Karen Albright, Susan Baird, Brenda Crowe, Linda Eres, Marjorie Korn, Leslie Maginn, Mark McCormick, Elisabeth D Root, Thomas Vierzba, Frederick S Wamboldt, Jeffrey J Swigris
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases
Stefano Aliberti, Grazia Messinesi, Silvia Gamberini, Sveva Maggiolini, Dina Visca, Vanni Galavotti, Fabio Giuliani, Roberto Cosentini, Anna Maria Brambilla, Francesco Blasi, Raffaele Scala, Mauro Carone, Francesca Luisi, Sergio Harari, Antonio Voza, Antonio Esquinas, Alberto Pesci
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Intravenous insulin therapy during lung resection does not affect lung function or surfactant proteins
Zdenek Ručka, Irena Koutná, Lenka Tesařová, Michaela Potěšilová, Stanislav Stejskal, Pavel Šimara, Petr Vaňhara, Jan Doležel, Vaclav Zvoníček, Oldřich Coufal, Ivan Čapov
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
TargetCOPD: a pragmatic randomised controlled trial of targeted case finding for COPD versusroutine practice in primary care: protocol
Rachel E Jordan, Peymané Adab, Sue Jowett, Jen L Marsh, Richard D Riley, Alexandra Enocson, Martin R Miller, Brendan G Cooper, Alice M Turner, Jon G Ayres, Kar Keung Cheng, Kate Jolly, Robert A Stockley, Sheila Greenfield, Stanley Siebert, Amanda Daley, David A Fitzmaurice
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Genes related to emphysema are enriched for ubiquitination pathways
Sergey Stepaniants, I-Ming Wang, Yves Boie, James Mortimer, Brian Kennedy, Mark Elliott, Shizu Hayashi, Honglin Luo, Jerry Wong, Leanna Loy, Silvija Coulter, Christopher J Roberts, James C Hogg, Don D Sin, Gary O’Neill, Michael Crackower, Melody Morris, Peter D Paré, Ma’en Obeidat
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Expiratory flow rate, breath hold and anatomic dead space influence electronic nose ability to detect lung cancer
Andras Bikov, Marton Hernadi, Beata Zita Korosi, Laszlo Kunos, Gabriella Zsamboki, Zoltan Sutto, Adam Domonkos Tarnoki, David Laszlo Tarnoki, Gyorgy Losonczy, Ildiko Horvath
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Pulsed direct and constant direct currents in the pilocarpine iontophoresis sweat chloride test
Carla Cristina Souza Gomez, Maria de Fatima Servidoni, Fernando Augusto de Lima Marson, Paulo Jose Coelho Canavezi, Adriana Mendes Vinagre, Eduardo Tavares Costa, Antonio Fernando Ribeiro, Maria Angela Gonçalves de Oliveira Ribeiro, Adyleia Aparecida Dalbo Contrera Toro, Celia Regina Pavan, Michelle Vivine Sá dos Santos Rondon, Sonia Leticia Silva Lorena, Francisco Ubaldi Vieria Junior, Jose Dirceu Ribeiro
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Aclidinium improves exercise endurance, dyspnea, lung hyperinflation, and physical activity in patients with COPD: a randomized, placebo-controlled, crossover trial
Kai M Beeh, Henrik Watz, Luis Puente-Maestu, Luis de Teresa, Diana Jarreta, Cynthia Caracta, Esther Garcia Gil, Helgo Magnussen
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
A dose-ranging study of the bronchodilator effects of abediterol (LAS100977), a long-acting β2-adrenergic agonist, in asthma; a Phase II, randomized study
Dave Singh, Helena Pujol, Anna Ribera, Beatriz Seoane, Eric Massana, Carol Astbury, Sandrine Ruiz, Gonzalo de Miquel
01.12.2014 | Study protocol | Ausgabe 1/2014
Open Access
The incidence of cardiovascular events after hospitalization due to CAP and their association with different inflammatory markers
Olga Rajas, Mara Ortega-Gómez, José María Galván Román, José Curbelo, Guillermo Fernández Jiménez, Lorena Vega Piris, Francisco Rodríguez Salvanes, Belén Arnalich, Sergio Luquero Bueno, Ana Díaz López, Hortensia de la Fuente, Carmen Suárez, Julio Ancochea, Javier Aspa
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Epidemiology and long-term survival of pulmonary arterial hypertension in the Czech Republic: a retrospective analysis of a nationwide registry
Pavel Jansa, Jiri Jarkovsky, Hikmet Al-Hiti, Jana Popelova, David Ambroz, Tomas Zatocil, Regina Votavova, Pavel Polacek, Jana Maresova, Michael Aschermann, Petr Brabec, Ladislav Dusek, Ales Linhart
01.12.2014 | Research article | Ausgabe 1/2014
Open Access
Quantitative analysis of lung elastic fibers in idiopathic pleuroparenchymal fibroelastosis (IPPFE): comparison of clinical, radiological, and pathological findings with those of idiopathic pulmonary fibrosis (IPF)
Noriyuki Enomoto, Hideki Kusagaya, Yoshiyuki Oyama, Masato Kono, Yusuke Kaida, Shigeki Kuroishi, Dai Hashimoto, Tomoyuki Fujisawa, Koshi Yokomura, Naoki Inui, Yutaro Nakamura, Takafumi Suda
01.12.2014 | Erratum | Ausgabe 1/2014
Open Access
Erratum to: Singing classes for chronic obstructive pulmonary disease: a randomized controlled trial
Victoria M Lord, Victoria J Hume, Julia L Kelly, Phoene Cave, Judith Silver, Maya Waldman, Chris White, Cayley Smith, Rebecca Tanner, Melissa Sanchez, William D-C Man, Michael I Polkey, Nicholas S Hopkinson
