Skip to main content
Erschienen in: The journal of nutrition, health & aging 8/2018

28.05.2018

BMI, Waist Circumference and All-Cause Mortality in a Middle-Aged and Elderly Chinese Population

verfasst von: H. Hu, J. Wang, X. Han, Y. Li, F. Wang, J. Yuan, X. Miao, H. Yang, Meian He

Erschienen in: The journal of nutrition, health & aging | Ausgabe 8/2018

Einloggen, um Zugang zu erhalten

Abstract

Objective

To investigate the association of obesity and all-cause mortality in a sample of middle-aged and elderly population.

Design and Setting

Information of participants was collected in the Dongfeng-Tongji study, a perspective cohort study of Chinese occupational population. The main outcome was risk of death after 8.5 years of follow-up.

Participants and measurements

We examined the association of BMI, waist circumference (WC, and waist–height ratio (WHtR) with all-cause mortality in the Dongfeng-Tongji cohort study (n=26,143). Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CI) for all-cause mortality. Area under the receiver operating characteristic curves and net reclassification improvement (NRI) were used to calculate the power of prediction models.

Results

During a mean of 8.5 years of follow-up, 2,246 deaths were identified. There is a U-shaped association of BMI with all-cause mortality in the middle-aged and elderly Chinese population. Compared with individuals with normal BMI, underweight was positively (HR=2.16, 95% CI: 1.73, 2.69) while overweight (HR=0.75, 95% CI: 0.67, 0.84) and obesity (HR=0.67, 95% CI: 0.56, 0.79) were negatively associated with all-cause mortality after adjustment for potential confounders including WC. In contrast, WC (Q5 vs. Q1, HR=1.55, 95% CI: 1.29, 1.86) and WHtR (Q5 vs.Q1, HR=1.69, 95% CI: 1.40, 2.04) were positively associated with mortality after further adjustment for BMI (P trend < 0.001). Addition of both BMI and WC into the all-cause mortality predictive model significantly increased AUC (P =0.0002) and NRI (NRI = 2.57%, P = 0.0007).

Conclusions

BMI and WC/WHtR were independently associated with all-cause mortality after mutual adjustment. Combination of BMI and WC/WHtR improved the predictive ability of all-cause mortality risk in the middle-aged and elderly population.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
Metadaten
Titel
BMI, Waist Circumference and All-Cause Mortality in a Middle-Aged and Elderly Chinese Population
verfasst von
H. Hu
J. Wang
X. Han
Y. Li
F. Wang
J. Yuan
X. Miao
H. Yang
Meian He
Publikationsdatum
28.05.2018
Verlag
Springer Paris
Erschienen in
The journal of nutrition, health & aging / Ausgabe 8/2018
Print ISSN: 1279-7707
Elektronische ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-018-1047-z

Weitere Artikel der Ausgabe 8/2018

The journal of nutrition, health & aging 8/2018 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.