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01.07.2013 | Original paper

Body mass index, body mass change, and risk of oral cavity cancer: results of a large population-based case–control study, the ICARE study

verfasst von: Loredana Radoï, Sophie Paget-Bailly, Diane Cyr, Alexandra Papadopoulos, Florence Guida, Chloé Tarnaud, Gwenn Menvielle, Annie Schmaus, Sylvie Cénée, Matthieu Carton, Bénédicte Lapôtre-Ledoux, Patricia Delafosse, Isabelle Stücker, Danièle Luce

Erschienen in: Cancer Causes & Control | Ausgabe 7/2013

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Abstract

Objective

The association between body mass index (BMI) and the risk of oral cavity cancer, suggested by the few available studies, is controversial because of weight loss preceding cancer diagnosis and possible confounding by tobacco and alcohol consumption. The aim of this study was to evaluate in France, a high-incidence country, the association between the risk of oral cavity cancer and body mass index at interview, 2 years before the interview and at age 30, as well as BMI change.

Methods

We used data from a population-based case–control study, the Investigation of occupational and environmental CAuses of REspiratory cancers study, with personal interviews and standardized questionnaires including 689 cases of oral cavity squamous cell carcinoma and 3,481 controls. Odds ratios (ORs) and 95 % confidence intervals (95 % CI) were estimated by unconditional logistic regression and were adjusted for gender, age, area of residence, education, tobacco smoking, and alcohol drinking.

Results

ORs were increased in underweight subjects at interview (OR 6.25, 95 % CI 3.74–10.45). No association with underweight 2 years before the interview and at age 30 was found. Overweight and obesity at interview, 2 years before the interview and at age 30 were associated with decreased ORs (ranging from 0.13 to 0.60). BMI gain greater than 5 % between age 30 and 2 years before the interview was inversely associated with oral cavity cancer (OR 0.42, 95 % CI 0.33–0.54). These associations were stronger in men, and in smokers and drinkers.

Conclusion

These results add further support to the existence of a reduced risk of oral cavity cancer among overweight and obese people or among people who increased their BMI in adulthood. The underlying mechanisms remain to be clarified.

World Health Organization (WHO) (2007) International classification of Diseases, 10th Revision. WHO Geneva

Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127(12):2893–2917PubMedCrossRef

de Camargo CM, Voti L, Guerra-Yi M, Chapuis F, Mazuir M, Curado MP (2010) Oral cavity cancer in developed and in developing countries: population-based incidence. Head Neck 32(3):357–367

Radoi L, Paget-Bailly S, Cyr D et al (2013) Tobacco smoking, alcohol drinking and risk of oral cavity cancer by subsite: results of a French population-based case–control study, the ICARE study. Eur J Cancer Prev 22(3):268–276PubMedCrossRef

Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371(9612):569–578PubMedCrossRef

Vainio H, Kaaks R, Bianchini F (2002) Weight control and physical activity in cancer prevention: international evaluation of the evidence. Eur J Cancer Prev 11(Suppl 2):S94–S100PubMed

World Cancer Research Fund (WCRF) (2007) Food, nutrition, physical activity and the prevention of cancer: a global perspective, 2nd edn. American Institute for Cancer Research, Washington

D’Avanzo B, La VC, Talamini R, Franceschi S (1996) Anthropometric measures and risk of cancers of the upper digestive and respiratory tract. Nutr Cancer 26(2):219–227PubMedCrossRef

Garavello W, Randi G, Bosetti C et al (2006) Body size and laryngeal cancer risk. Ann Oncol 17(9):1459–1463PubMedCrossRef

10.

Gaudet MM, Olshan AF, Chuang SC et al (2010) Body mass index and risk of head and neck cancer in a pooled analysis of case–control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Int J Epidemiol 39(4):1091–1102PubMedCrossRef

11.

Kabat GC, Chang CJ, Wynder EL (1994) The role of tobacco, alcohol use, and body mass index in oral and pharyngeal cancer. Int J Epidemiol 23(6):1137–1144PubMedCrossRef

12.

Kreimer AR, Randi G, Herrero R, Castellsague X, La VC, Franceschi S (2006) Diet and body mass, and oral and oropharyngeal squamous cell carcinomas: analysis from the IARC multinational case–control study. Int J Cancer 118(9):2293–2297PubMedCrossRef

13.

Lubin JH, Gaudet MM, Olshan AF et al (2010) Body mass index, cigarette smoking, and alcohol consumption and cancers of the oral cavity, pharynx, and larynx: modeling odds ratios in pooled case–control data. Am J Epidemiol 171(12):1250–1261PubMedCrossRef

14.

Ng SK, Kabat GC, Wynder EL (1993) Oral cavity cancer in non-users of tobacco. J Natl Cancer Inst 85(9):743–745PubMedCrossRef

15.

Nieto A, Sanchez MJ, Quintana MJ et al (2002) BMI throughout life, intake of vitamin supplements and oral cancer in Spain. IARC Sci Publ 156:259–261PubMed

16.

Nieto A, Sanchez MJ, Martinez C et al (2003) Lifetime body mass index and risk of oral cavity and oropharyngeal cancer by smoking and drinking habits. Br J Cancer 89(9):1667–1671PubMedCrossRef

17.

Rajkumar T, Sridhar H, Balaram P et al (2003) Oral cancer in Southern India: the influence of body size, diet, infections and sexual practices. Eur J Cancer Prev 12(2):135–143PubMedCrossRef

18.

Gaudet MM, Patel AV, Sun J et al (2012) Prospective studies of body mass index with head and neck cancer incidence and mortality. Cancer Epidemiol Biomarkers Prev 21(3):497–503PubMedCrossRef

19.

Hashibe M, Hunt J, Wei M, Buys S, Gren L, Lee YC (2012) Tobacco, alcohol, body mass index, physical activity, and the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian (PLCO) cohort. Head Neck. doi:10.1002/hed.23052 PubMed

20.

Park SL, Lee YC, Marron M et al (2010) The association between change in body mass index and upper aerodigestive tract cancers in the ARCAGE project: multicenter case–control study. Int J Cancer 128(6):1449–1461CrossRef

21.

Tarleton HP, Park SL, Zhu WM et al (2012) Body mass index change in adulthood and lung and upper aerodigestive tract cancers. Int J Cancer 131(6):1407–1416PubMedCrossRef

22.

Lubin JH, Muscat J, Gaudet MM et al (2011) An examination of male and female odds ratios by BMI, cigarette smoking, and alcohol consumption for cancers of the oral cavity, pharynx, and larynx in pooled data from 15 case–control studies. Cancer Causes Control 22(9):1217–1231PubMedCrossRef

23.

Hashibe M, Brennan P, Chuang SC et al (2009) Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiol Biomarkers Prev 18(2):541–550PubMedCrossRef

24.

Lubin JH, Purdue M, Kelsey K et al (2009) Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case–control studies. Am J Epidemiol 170(8):937–947PubMedCrossRef

25.

Hashibe M, Sankaranarayanan R, Thomas G et al (2000) Alcohol drinking, body mass index and the risk of oral leukoplakia in an Indian population. Int J Cancer 88(1):129–134PubMedCrossRef

26.

Hashibe M, Sankaranarayanan R, Thomas G et al (2002) Body mass index, tobacco chewing, alcohol drinking and the risk of oral submucous fibrosis in Kerala, India. Cancer Causes Control 13(1):55–64PubMedCrossRef

27.

Luce D, Stucker I, Icare Study Group (2011) Investigation of occupational and environmental causes of respiratory cancers (ICARE): a multicenter, population-based case–control study in France. BMC Public Health 11(1):928PubMedCrossRef

28.

World Health Organization (WHO) (2000) International classification of diseases for oncology, 3rd edn. WHO, Geneva

29.

Rothman KJ, Greenland S, Lash TL (2008) Study design and conduct. Case–control studies. In: Rothman KJ, Greenland S, Lash TL (eds) Modern epidemiology, 3rd edn. Lippincott Williams and Wilkins, Philadelphia, pp 117–119

30.

World Health Organization (2000) Obesity. Preventing and managing the global epidemic. Report of a WHO Consultation. WHO Technical Report Series 894 Geneva: World Health Organization, 2000

31.

Kabat GC, Miller AB, Rohan TE (2007) Body mass index and lung cancer risk in women. Epidemiology 18(5):607–612PubMedCrossRef

32.

Kabat GC, Kim M, Hunt JR, Chlebowski RT, Rohan TE (2008) Body mass index and waist circumference in relation to lung cancer risk in the Women’s Health Initiative. Am J Epidemiol 168(2):158–169PubMedCrossRef

33.

Kanashiki M, Sairenchi T, Saito Y, Ishikawa H, Satoh H, Sekizawa K (2005) Body mass index and lung cancer: a case–control study of subjects participating in a mass-screening program. Chest 128(3):1490–1496PubMedCrossRef

34.

Koh WP, Yuan JM, Wang R, Lee HP, Yu MC (2010) Body mass index and smoking-related lung cancer risk in the Singapore Chinese health study. Br J Cancer 102(3):610–614PubMedCrossRef

35.

Olson JE, Yang P, Schmitz K, Vierkant RA, Cerhan JR, Sellers TA (2002) Differential association of body mass index and fat distribution with three major histologic types of lung cancer: evidence from a cohort of older women. Am J Epidemiol 156(7):606–615PubMedCrossRef

36.

Smith L, Brinton LA, Spitz MR et al (2012) Body mass index and risk of lung cancer among never, former, and current smokers. J Natl Cancer Inst 104(10):778–789PubMedCrossRef

37.

Tarnaud C, Guida F, Papadopoulos A et al (2012) Body mass index and lung cancer risk: results from the ICARE study, a large, population-based case–control study. Cancer Causes Control 23(7):1113–1126PubMedCrossRef

38.

Yang Y, Dong J, Sun K et al (2013) Obesity and incidence of lung cancer: a meta-analysis. Int J Cancer 132(5):1162–1169PubMedCrossRef

39.

Gallus S, La VC, Levi F, Simonato L, Dal ML, Franceschi S (2001) Leanness and squamous cell oesophageal cancer. Ann Oncol 12(7):975–979PubMedCrossRef

40.

Smith M, Zhou M, Whitlock G et al (2008) Esophageal cancer and body mass index: results from a prospective study of 220,000 men in China and a meta-analysis of published studies. Int J Cancer 122(7):1604–1610PubMedCrossRef

41.

Chiolero A, Faeh D, Paccaud F, Cornuz J (2008) Consequences of smoking for body weight, body fat distribution, and insulin resistance. Am J Clin Nutr 87(4):801–809PubMed

42.

Mizoue T, Kasai H, Kubo T, Tokunaga S (2006) Leanness, smoking, and enhanced oxidative DNA damage. Cancer Epidemiol Biomarkers Prev 15(3):582–585PubMedCrossRef

43.

Mizoue T, Tokunaga S, Kasai H, Kawai K, Sato M, Kubo T (2007) Body mass index and oxidative DNA damage: a longitudinal study. Cancer Sci 98(8):1254–1258PubMedCrossRef

44.

Godschalk RW, Feldker DE, Borm PJ, Wouters EF, van Schooten FJ (2002) Body mass index modulates aromatic DNA adduct levels and their persistence in smokers. Cancer Epidemiol Biomarkers Prev 11(8):790–793PubMed

45.

Liu S, Serdula MK, Williamson DF, Mokdad AH, Byers T (1994) A prospective study of alcohol intake and change in body weight among US adults. Am J Epidemiol 140(10):912–920PubMed

46.

Wannamethee SG, Field AE, Colditz GA, Rimm EB (2004) Alcohol intake and 8-year weight gain in women: a prospective study. Obes Res 12(9):1386–1396PubMedCrossRef

47.

Williamson DF, Forman MR, Binkin NJ, Gentry EM, Remington PL, Trowbridge FL (1987) Alcohol and body weight in United States adults. Am J Public Health 77(10):1324–1330PubMedCrossRef

48.

French MT, Norton EC, Fang H, Maclean JC (2010) Alcohol consumption and body weight. Health Econ 19(7):814–832PubMedCrossRef

49.

Ligier K, Belot A, Launoy G et al (2011) Descriptive epidemiology of upper aerodigestive tract cancers in France: incidence over 1980–2005 and projection to 2010. Oral Oncol 47(4):302–307PubMedCrossRef

50.

Charles MA, Eschwege E, Basdevant A (2008) Monitoring the obesity epidemic in France: the Obepi surveys 1997–2006. Obesity (Silver Spring) 16(9):2182–2186CrossRef

51.

Niedhammer I, Bugel I, Bonenfant S, Goldberg M, Leclerc A (2000) Validity of self-reported weight and height in the French GAZEL cohort. Int J Obes Relat Metab Disord 24(9):1111–1118PubMedCrossRef

52.

Stommel M, Schoenborn CA (2009) Accuracy and usefulness of BMI measures based on self-reported weight and height: findings from the NHANES & NHIS 2001–2006. BMC Public Health 9:421PubMedCrossRef

53.

Boeing H, Dietrich T, Hoffmann K et al (2006) Intake of fruits and vegetables and risk of cancer of the upper aero-digestive tract: the prospective EPIC-study. Cancer Causes Control 17(7):957–969PubMedCrossRef

54.

Freedman ND, Park Y, Subar AF et al (2008) Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study. Int J Cancer 122(10):2330–2336PubMedCrossRef

55.

Lagiou P, Talamini R, Samoli E et al (2009) Diet and upper-aerodigestive tract cancer in Europe: the ARCAGE study. Int J Cancer 124(11):2671–2676PubMedCrossRef

56.

Nicolotti N, Chuang SC, Cadoni G et al (2011) Recreational physical activity and risk of head and neck cancer: a pooled analysis within the international head and neck cancer epidemiology (INHANCE) Consortium. Eur J Epidemiol 26(8):619–628PubMedCrossRef

57.

Pavia M, Pileggi C, Nobile CG, Angelillo IF (2006) Association between fruit and vegetable consumption and oral cancer: a meta-analysis of observational studies. Am J Clin Nutr 83(5):1126–1134PubMed

Titel: Body mass index, body mass change, and risk of oral cavity cancer: results of a large population-based case–control study, the ICARE study
verfasst von: Loredana Radoï
Sophie Paget-Bailly
Diane Cyr
Alexandra Papadopoulos
Florence Guida
Chloé Tarnaud
Gwenn Menvielle
Annie Schmaus
Sylvie Cénée
Matthieu Carton
Bénédicte Lapôtre-Ledoux
Patricia Delafosse
Isabelle Stücker
Danièle Luce
Publikationsdatum: 01.07.2013
Verlag: Springer Netherlands
Erschienen in: Cancer Causes & Control / Ausgabe 7/2013
Print ISSN: 0957-5243
Elektronische ISSN: 1573-7225
DOI: https://doi.org/10.1007/s10552-013-0223-z

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Body mass index, body mass change, and risk of oral cavity cancer: results of a large population-based case–control study, the ICARE study

Abstract

Objective

Methods

Results

Conclusion

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Methods

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