Erschienen in:
02.06.2017 | Letter to the Editor
Bone mineral density in older patients with never-treated congenital hypogonadotropic hypogonadism
verfasst von:
Luigi Maione, Annamaria Colao, Jacques Young
Erschienen in:
Endocrine
|
Ausgabe 1/2018
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Excerpt
Sex steroids are major regulators of skeletal development and bone mineral content, and sex steroid deficiency can thus lead to osteoporosis and fractures in later life [
1]. Hypogonadism in both genders is associated with bone loss and frailty. Its deleterious effects on bone mineral density (BMD) are epitomized by women with ovarian failure and by aging men undergoing surgical or pharmacological castration for prostate cancer [
1]. …