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Calcified Tissue International
Erschienen in: Calcified Tissue International 3/2015

01.09.2015 | Review

Bone’s Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment

verfasst von: Y. Bala, E. Seeman

Erschienen in: Calcified Tissue International | Ausgabe 3/2015

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Abstract

Type 1 collagen matrix volume, its degree of completeness of its mineralization, the extent of collagen crosslinking and water content, and the non-collagenous proteins like osteopontin and osteocalcin comprise the main constituents of bone’s material composition. Each influences material strength and change in different ways during advancing age, health, disease, and drug therapy. These traits are not quantifiable using bone densitometry and their plurality is better captured by the term bone ‘qualities’ than ‘quality’. These qualities are the subject of this manuscript.
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Metadaten
Titel
Bone’s Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment
verfasst von
Y. Bala
E. Seeman
Publikationsdatum
01.09.2015
Verlag
Springer US
Erschienen in
Calcified Tissue International / Ausgabe 3/2015
Print ISSN: 0171-967X
Elektronische ISSN: 1432-0827
DOI
https://doi.org/10.1007/s00223-015-9971-y

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