Ausgabe 2-3/2010
Special Issue: "Transgenic Modeling of Neurodegenerative Disorders"
Inhalt (13 Artikel)
Introduction to the special issue of Brain Structure and Function on transgenic modeling of neurodegenerative disorders
Patrick R. Hof, Gregory A. Elder
APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis
Leslie Crews, Edward Rockenstein, Eliezer Masliah
Presenilin transgenic mice as models of Alzheimer’s disease
Gregory A. Elder, Miguel A. Gama Sosa, Rita De Gasperi, Dara L. Dickstein, Patrick R. Hof
Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer’s disease
Hisaaki Takahashi, Ivona Brasnjevic, Bart P. F. Rutten, Nicolien Van Der Kolk, Daniel P. Perl, Constantin Bouras, Harry W. M. Steinbusch, Christoph Schmitz, Patrick R. Hof, Dara L. Dickstein
Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau
Dara L. Dickstein, Hannah Brautigam, Steven D. Stockton Jr., James Schmeidler, Patrick R. Hof
Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models
Jennifer I. Luebke, Christina M. Weaver, Anne B. Rocher, Alfredo Rodriguez, Johanna L. Crimins, Dara L. Dickstein, Susan L. Wearne, Patrick R. Hof
Immunotherapeutic approaches for Alzheimer’s disease in transgenic mouse models
Thomas Wisniewski, Allal Boutajangout
Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice
Kevin Chen, Frances J. Northington, Lee J. Martin
Modeling familial British and Danish dementia
Holly J. Garringer, Jill Murrell, Luciano D’Adamio, Bernardino Ghetti, Ruben Vidal
Transgenic Drosophila models of Alzheimer’s disease and tauopathies
Kanae Iijima-Ando, Koichi Iijima
Understanding the molecular basis of Alzheimer’s disease using a Caenorhabditis elegans model system
Collin Y. Ewald, Chris Li
Transgenic zebrafish models of neurodegenerative diseases
Jonathan J. Sager, Qing Bai, Edward A. Burton