The collection of brain and related tissue has a long history [
1]. In terms of dementia, a more systematic examination of the relationship between brain pathology and clinical symptoms can be traced to Alois Alzheimer’s group in Munich in the early 1900s [
2]. The use of human brain tissue is essential to increase our understanding of dementia as it gives us the gold standard of disease pathogenesis and clues as to the molecular mechanisms that underpin the various diseases and conditions. From such human studies, experimental models can be interrogated against this standard and new treatment strategies can be discovered for these socially and economically devastating conditions. …