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Erschienen in: Breast Cancer 2/2014

01.03.2014 | Original Article

Breast biopsy for mammographically detected nonpalpable lesions using a vacuum-assisted biopsy device (Mammotome) and upright-type stereotactic mammography unit without a digital imaging system: experience of 500 biopsies

verfasst von: Shozo Ohsumi, Naruto Taira, Daisuke Takabatake, Seiki Takashima, Fumikata Hara, Mina Takahashi, Sachiko Kiyoto, Kenjiro Aogi, Rieko Nishimura

Erschienen in: Breast Cancer | Ausgabe 2/2014

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Abstract

Background

The most common diagnostic procedure in the United States for mammographically detected nonpalpable lesions is a combination of a vacuum-assisted biopsy device and a prone-type biopsy table. We have used an upright-type stereotactic mammography unit without a digital imaging system instead of the prone table.

Patients and methods

Five-hundred ten biopsies of 506 mammographically detected nonpalpable breast lesions in 488 patients, consisting of 445 lesions with microcalcifications alone, 39 masses without calcifications, and 22 with both masses and microcalcifications, were attempted using a combination of a vacuum-assisted device (Mammotome) and an upright unit without a digital imaging system in a sitting position between May 1999 and February 2007.

Results

Breast tissue was obtained in 497 biopsies. Microcalcifications were confirmed radiographically in the tissue of 447 out of 459 biopsies from lesions with microcalcifications (97.4 %). One hundred thirty-seven were diagnosed as malignant, 10 as atypical ductal hyperplasia, 345 as benign, and 1 was not diagnosable. The underestimation rate was 28.0 %. Overall, 26 patients (5.1 %) had vasovagal reactions, while 19 (3.8 %) experienced mild subcutaneous bleeding. Two hundred fifty of 350 lesions, for which biopsy diagnoses were benign, were followed for a median period of 33 months. Four lesions turned out to be malignant. The false-negative rate was 2.8 %.

Conclusion

The biopsy technique using the combination of the Mammotome and an upright unit without a digital imaging system is cost-effective, safe, and accurate, and should be regarded as one of the standard biopsy methods for mammographically detected nonpalpable lesions.
Literatur
1.
Zurück zum Zitat Gotzsche PC, Nielsen M. Screening for breast cancer with mammography. Cochrane Database Syst Rev 2006;4:CD001877. Gotzsche PC, Nielsen M. Screening for breast cancer with mammography. Cochrane Database Syst Rev 2006;4:CD001877.
2.
Zurück zum Zitat Ohsumi S, Takashima S, Aogi K, Ishizaki M, Mandai K. Breast biopsy for mammographically detected non-palpable lesions using a vacuum-assisted biopsy device (Mammotome) and an upright-type stereotactic mammography unit. Jpn J Clin Oncol. 2001;31:527–31.PubMedCrossRef Ohsumi S, Takashima S, Aogi K, Ishizaki M, Mandai K. Breast biopsy for mammographically detected non-palpable lesions using a vacuum-assisted biopsy device (Mammotome) and an upright-type stereotactic mammography unit. Jpn J Clin Oncol. 2001;31:527–31.PubMedCrossRef
3.
Zurück zum Zitat Nisbet AP, Borthwick-Clarke A, Scott N. 11-gauge vacuum assisted directional biopsy of breast calcifications, using upright stereotactic guidance. Eur J Radiol. 2000;36:144–6.PubMedCrossRef Nisbet AP, Borthwick-Clarke A, Scott N. 11-gauge vacuum assisted directional biopsy of breast calcifications, using upright stereotactic guidance. Eur J Radiol. 2000;36:144–6.PubMedCrossRef
4.
Zurück zum Zitat Welle GJ, Clark M, Loos S, Pauls D, Warden D, Sheffield M, et al. Stereotactic breast biopsy: recumbent biopsy using add-on upright equipment. Am J Roentogenol. 2000;175:59–63.CrossRef Welle GJ, Clark M, Loos S, Pauls D, Warden D, Sheffield M, et al. Stereotactic breast biopsy: recumbent biopsy using add-on upright equipment. Am J Roentogenol. 2000;175:59–63.CrossRef
5.
Zurück zum Zitat Georgian-Smith D, D’Orsi C, Morris E, Clark CF Jr, Liberty E, Lehman CD. Stereotactic biopsy of the breast using an upright unit, a vacuum-suction needle, and a lateral arm-support system. Am J Roentogenol. 2002;178:1017–24.CrossRef Georgian-Smith D, D’Orsi C, Morris E, Clark CF Jr, Liberty E, Lehman CD. Stereotactic biopsy of the breast using an upright unit, a vacuum-suction needle, and a lateral arm-support system. Am J Roentogenol. 2002;178:1017–24.CrossRef
6.
Zurück zum Zitat American College of Radiology. Illustrated breast imaging reporting and data system (BI-RADS), 3rd ed. Reston: American College of Radiology; 1998. American College of Radiology. Illustrated breast imaging reporting and data system (BI-RADS), 3rd ed. Reston: American College of Radiology; 1998.
7.
Zurück zum Zitat Page DL, Anderson TJ, Roger LW. Epithelial hyperplasia. In: Page DL, Anderson TJ (eds) Diagnostic histopathology of the breast. Edinburgh: Churchill Livingstone; 1987. p. 120–56. Page DL, Anderson TJ, Roger LW. Epithelial hyperplasia. In: Page DL, Anderson TJ (eds) Diagnostic histopathology of the breast. Edinburgh: Churchill Livingstone; 1987. p. 120–56.
8.
Zurück zum Zitat Liberman L, Smolkin JH, Dershaw DD, Morris EA, Abramson AF, Rosen PP. Calcification retrieval at stereotactic, 11-gauge, directional, vacuum-assisted breast biopsy. Radiology. 1998;208:251–60.PubMed Liberman L, Smolkin JH, Dershaw DD, Morris EA, Abramson AF, Rosen PP. Calcification retrieval at stereotactic, 11-gauge, directional, vacuum-assisted breast biopsy. Radiology. 1998;208:251–60.PubMed
9.
Zurück zum Zitat Brem RF, Behrndt VS, Sanow L, Gatewood OM. Atypical ductal hyperplasia: Histologic underestimation of carcinoma in tissue harvested from impalpable breast lesions using 11-gauge stereotactically guided directional vacuum-assisted biopsy. Am J Roentogenol. 1999;172:1405–7.CrossRef Brem RF, Behrndt VS, Sanow L, Gatewood OM. Atypical ductal hyperplasia: Histologic underestimation of carcinoma in tissue harvested from impalpable breast lesions using 11-gauge stereotactically guided directional vacuum-assisted biopsy. Am J Roentogenol. 1999;172:1405–7.CrossRef
10.
Zurück zum Zitat Won B, Reynolds HE, Lazaridis CL, Jackson VP. Stereotactic biopsy of ductal carcinoma in situ of breast using an 11-gauge vacuum-assisted device: persistent underestimation of disease. Am J Roentogenol. 1999;173:227–9.CrossRef Won B, Reynolds HE, Lazaridis CL, Jackson VP. Stereotactic biopsy of ductal carcinoma in situ of breast using an 11-gauge vacuum-assisted device: persistent underestimation of disease. Am J Roentogenol. 1999;173:227–9.CrossRef
11.
Zurück zum Zitat Pfarl G, Helbich TH, Riedl CC, Wagner T, Gnant M, Rudas M, et al. Stereotactic 11-gauge vacuum-assisted breast biopsy: a validation study. Am J Roentogenol. 2002;179:1503–7.CrossRef Pfarl G, Helbich TH, Riedl CC, Wagner T, Gnant M, Rudas M, et al. Stereotactic 11-gauge vacuum-assisted breast biopsy: a validation study. Am J Roentogenol. 2002;179:1503–7.CrossRef
12.
Zurück zum Zitat Rao A, Parker S, Ratzer E, Stephens J, Fenoglio M. Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy. Am J Surg. 2002;184:534–7.PubMedCrossRef Rao A, Parker S, Ratzer E, Stephens J, Fenoglio M. Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy. Am J Surg. 2002;184:534–7.PubMedCrossRef
13.
Zurück zum Zitat Winchester DJ, Bernstein JR, Jeske JM, Nicholson MH, Hahn EA, Goldschmidt RA, et al. Upstaging of atypical ductal hyperplasia after vacuum-assisted 11-gauge stereotactic core needle biopsy. Arch Surg. 2003;138:619–23.PubMedCrossRef Winchester DJ, Bernstein JR, Jeske JM, Nicholson MH, Hahn EA, Goldschmidt RA, et al. Upstaging of atypical ductal hyperplasia after vacuum-assisted 11-gauge stereotactic core needle biopsy. Arch Surg. 2003;138:619–23.PubMedCrossRef
14.
Zurück zum Zitat Kettritz U, Rotter K, Schreer I, Murauer M, Schulz-Wendtland R, Peter D, et al. Stereotactic vacuum-assisted breast biopsy in 2874 patients: a multicenter study. Cancer. 2004;100:245–51.PubMedCrossRef Kettritz U, Rotter K, Schreer I, Murauer M, Schulz-Wendtland R, Peter D, et al. Stereotactic vacuum-assisted breast biopsy in 2874 patients: a multicenter study. Cancer. 2004;100:245–51.PubMedCrossRef
15.
Zurück zum Zitat Jackman RJ, Marzoni FA Jr, Rosenberg J. False-negative diagnoses at stereotactic vacuum-assisted needle breast biopsy: long-term follow-up of 1,280 lesions and review of literature. Am J Roentogenol. 2009;192:341–51.CrossRef Jackman RJ, Marzoni FA Jr, Rosenberg J. False-negative diagnoses at stereotactic vacuum-assisted needle breast biopsy: long-term follow-up of 1,280 lesions and review of literature. Am J Roentogenol. 2009;192:341–51.CrossRef
16.
Zurück zum Zitat Lai JT, Burrowes P, MacGregor JH. Diagnostic accuracy of a stereotactically guided vacuum-assisted large-core breast biopsy program in Canada. Can Assoc Radiol J. 2001;52:223–7.PubMed Lai JT, Burrowes P, MacGregor JH. Diagnostic accuracy of a stereotactically guided vacuum-assisted large-core breast biopsy program in Canada. Can Assoc Radiol J. 2001;52:223–7.PubMed
17.
Zurück zum Zitat Apesteguia L, Mellado M, Saenz J, Cordero JL, Reparaz B, Miguel C. Vacuum-assisted breast biopsy on digital stereotaxic table of nonpalpable lesions non-recognisable by ultrasonography. Eur Radiol. 2002;12:638–45.PubMedCrossRef Apesteguia L, Mellado M, Saenz J, Cordero JL, Reparaz B, Miguel C. Vacuum-assisted breast biopsy on digital stereotaxic table of nonpalpable lesions non-recognisable by ultrasonography. Eur Radiol. 2002;12:638–45.PubMedCrossRef
18.
Zurück zum Zitat Liberman L, Kaplan JB, Morris EA, Abramson AF, Menell JH, Dershaw DD. To excise or to sample the mammographic target: what is the goal of stereotactic 11-gauge vacuum-assisted breast biopsy? Am J Roentogenol. 2002;179:679–83.CrossRef Liberman L, Kaplan JB, Morris EA, Abramson AF, Menell JH, Dershaw DD. To excise or to sample the mammographic target: what is the goal of stereotactic 11-gauge vacuum-assisted breast biopsy? Am J Roentogenol. 2002;179:679–83.CrossRef
19.
Zurück zum Zitat Kettritz U. Stereotactic vacuum-assisted breast biopsy in 2874 patients. (reply to letter). Cancer. 2004;101:431.CrossRef Kettritz U. Stereotactic vacuum-assisted breast biopsy in 2874 patients. (reply to letter). Cancer. 2004;101:431.CrossRef
20.
Zurück zum Zitat Wunderbaldinger P, Wolf G, Turetschek K, Helbich TH. Comparison of sitting versus prone position for stereotactic large-core breast biopsy in surgically proven lesions. Am J Roentogenol. 2002;178:1221–5.CrossRef Wunderbaldinger P, Wolf G, Turetschek K, Helbich TH. Comparison of sitting versus prone position for stereotactic large-core breast biopsy in surgically proven lesions. Am J Roentogenol. 2002;178:1221–5.CrossRef
Metadaten
Titel
Breast biopsy for mammographically detected nonpalpable lesions using a vacuum-assisted biopsy device (Mammotome) and upright-type stereotactic mammography unit without a digital imaging system: experience of 500 biopsies
verfasst von
Shozo Ohsumi
Naruto Taira
Daisuke Takabatake
Seiki Takashima
Fumikata Hara
Mina Takahashi
Sachiko Kiyoto
Kenjiro Aogi
Rieko Nishimura
Publikationsdatum
01.03.2014
Verlag
Springer Japan
Erschienen in
Breast Cancer / Ausgabe 2/2014
Print ISSN: 1340-6868
Elektronische ISSN: 1880-4233
DOI
https://doi.org/10.1007/s12282-012-0360-3

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