Ausgabe Sonderheft 1/2000
Second International Symposium on the Molecular Biology of Breast Cancer
Inhalt (102 Artikel)
Denaturing high-performance liquid chromatography (DHPLC) as a fast tool to screen a control population for the occurrence of unclassified variants (UV) in the BRCA1 gene
N Arnold, E Gross, H Peper, K Bandick, W Jonat, M Kiechle
A novel BRCA2 gene mutation, 4081 insA, in a Finnish breast/ovarian cancer family associated with favourable clinical course
J Hartikainen, V Kataja, A Mannermaa
Breast cancer in young women: prevalence of LOH at p53, BRCA1 and BRCA2
SM Johnson, JA Shaw, RA Walker
BRCA1mutation analysis in breast and ovarian cancer families from Greece
I Konstantopoulou, C Croupis, A Ladopoulou, A Pantazidis, E Lianidou, K Venetsanou, E Efstathiou, M Petersen, J Janinis, G Fountzilas, E Chiotellis, D Yannoukakos
Germline TP53mutations in Finnish breast cancer patients
K Rapakko, M Allinen, K Syrjäkoski, P Vahteristo, P Huusko, K Vähäkangas, H Eerola, T Kainu, O-P Kallioniemi, H Nevanlinna, R Winqvist
Germline BRCA2 and somatic P53alterations in male breast cancer
B Csokay, N Udvarhelyi, E Olah
Constitutional alterations of 9p23-24 in independent BRCA2 breast cancer families
M Schwab, L Savelyeva, A Claas, H An, S Brouwers
kConFab: a unique Australasian research initiative for familial breast cancer
J Sambrook
Germline mutations of BRCA1-associated RING domain (BARD1) gene in breast and/or ovarian families negative for BRCA1 and 2 alterations
C Ghimenti, E Sensi, D Iandolo, G Cipollini, S Ricci, PF Conte, G Bevilacqua, MA Caligo
Relative expression of progesterone receptors A and B in premalignant and invasive breast lesions
P Mote, C Clarke
Phosphorylation of human progesterone receptors by MAPKs mediates transcriptional synergy between progestins and MEKK1 in human breast cancer cells
CA Lange, T Shen, KB Horwitz
Expression of Akt kinases related to ErbB2 and results of adjuvant therapy of breast cancer
O Stal, L Akerberg, B Nordenskjold, B Olsson, LE Rutqvist, L Skoog
Anti-HER2 mAb plus calicheamicin immunoconjugate linked on liposomal vinorelbine induces ADCC and apoptosis in HER2-positive high grade DCIS
J Giannos, P Ginopulos
Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients
J Alsner, M Yilmaz, P Guldberg, LL Hansen, J Overgaard
Studies of TP53 haplotypes in relation to LOH and TP53 mutations in breast cancer patients
A Langerød, TI Andersen, I Bukholm, A-L Børresen Dale
P53 mutations in breast and ovarian carcinomas from BRCA1 and 2 mutation carriers and noncarriers
E Sensi, C Ghimenti, G Cipollini, D Iandolo, G Naccarato, P Viacava, G Bevilacqua, MA Caligo
Constitutional alterations of the ATM gene in early-onset sporadic breast cancer
P Maillet, H Bonnefoi, A-P Sappino
Modulation of ATM gene expression in a murine mammary epithelial cell line
GV Vutskits, P Salmon, JV Soriano, C Cudre-Mauroux, D Trono, R Montesano, A-P Sappino
Loss of heterozygosity on chromosome arm 16q in breast cancer: clinical, molecular and statistical approaches
A-M Cleton-Jansen, HM van Beerendonk, NT ter Haar, PHC Eilers, HC van Houwelingen, BA Bonsing, VTHBM Smit, G-JB van Ommen, CJ Cornelisse
Analysis of chromosome alterations and the E-cadherin and FHIT genes in lobular breast cancer
S Ingvarsson, C Huiping, JG Jonasson, BA Agnarsson
Excluding TTC4 as a target for loss on chromosome 1p31 in human breast cancer
Y Hey, W Brintnell, L James, J Varley
Expression of variant forms of the MUC1 gene correlates with the invasiveness of breast cancer cells
R Zeillinger, B Schmid, D Tong, B Fasching, I Schiebl, M Stimpfl, A Obermair, S Leodolter
Low frequency of p16 INK4a promoter methylation in mammary carcinomas as revealed by positive display of methylated sites
R Lilischkis, H Kneitz, H Kreipe
Estrogen-dependent c-jun upregulation may control cyclin D1 expression
MD Planas-Silva, J Liu Donaher, RA Weinberg
Development of a high throughput, molecular diagnostic assay for predicting telomerase activity in breast cancer cell lines and tissues
L Elmore, A Akalin, L Gollahon, G Clarke, M Grimes, RT Burks, A Ferreira-Gonzalez, C Garrett, S Holt
Mammary epithelial cells immortalized by over-expression of the catalytic subunit of human telomerase may represent a model for mammary epithelial differentiation
J DiRenzo, R Rivera-Gonzalez, M Brown
Molecular analyses of human breast cancer metastasis: genetic markers of progression
K Driouch, R Lidereau
Ribozymes targeting the tumor suppressor BRCA1 lead to increased chemosensitivity to cisplatin and etoposide and chemoresistance to microtubule-interfering agents in HBL100 breast cancer cell line
S Lafarge, M Ferrara, YJ Bignon
Genetic alterations in ductal carcinoma in situ and invasive carcinoma of the breast
E Robanus-Maandag, C Bosch, C Vos, H Peterse, M van de Vijver
Identification of two novel breast cancer associated genes by the differential display method
N Maass, K Nagasaki, VR Jacobs, W Jonat
Expression profiling of BRCA1 associated breast tumors
EMJJ Berns, IL van Staveren, L Verhoog, JA Foekens, JGM Klijn
The importance of breast cancer research from a patient's view: the voices and visions of advocates
S Leigh
Genetic testing for BRCA1 and BRCA2 mutations - ready for implementation?
BL Weber
Other cancers in BRCA1 and BRCA2 mutation carriers: implications for counselling and follow up
B Ponder
Drug discovery in the p53 pathway
DP Lane, C Midgley, A Sparks, C Blattner, C Binden, S Laine
Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium
AF Olumi, GD Grossfeld, SW Hayward, PR Carroll, GR Cunha, P Hein, TD Tlsty
p53-mediated apoptosis and genomic instability syndromes
EA Spillare, XW Wang, SP Linke, A Robles, CC Harris
Lessons from TP53mutations in breast cancers: from carcinogen fingerprints to clinical correlates
P Hainaut, M Olivier
p53 action in apoptosis and senescence
SW Lowe, CA Schmitt, G Ferbeyre, AW Lin, E de Stanchina, M Soengas
Cancer susceptibility in ATM heterozygotes: do two distinct carrier populations exist?
RA Gatti, P Concannon
Clinical and pathological characteristics in patients with BRCA1/2-mutation associated with breast cancer (BC) with a long clinical follow-up
O Díez, C Pericay, M Domènech, J Brunet, J Cortés, J Balmaña, A Gómez, JJ López, MC Alonso, M Baiget
BRCA1, BRCA2 and pedigree genetic analysis to determine genetic risk in the UK Royal Marsden Hospital tamoxifen prevention trial
Z Kote-Jarai, TP Powles, S Ashley, DF Easton, L Assersohn, N Sodha, M Dowsett, B Gusterson, A Tidy, G Mitchell, RA Eeles
Mutational analysis of BRCA1 and BRCA2 genes in Spanish women with early-onset breast cancer
JI Martínez-Ferrandis, A Vega, P Marín-Garcia, F Barros, FJ Chaves, A Carracedo, ME Armengod, I Chirivella, A Lluch, J García-Conde, A Cervantes
One test to identify 50% of all Norwegian BRCA1 mutations
P Møller, E Hovig, K Lycke, RAP Stacy, OJ Dahlberg, A Hagen, B Hagen, K Løvslett, H Qvist, K Heimdal
X chromosome inactivation pattern in female patients with breast cancer
M Kristiansen, A Langer, GP Knudsen, BL Weber, A-L Børresen-Dale, KH Ørstavik
HRAS1 minisatellite alleles and breast cancer in Spanish women under age forty years
A Vega, JI Martínez, F Barros, P Marín-García, FJ Chavez, C Ruiz-Ponte, I Chirivella, A Lluch, A Cervantes, I García-Conde, ME Armengod, A Carracedo
Mammary-specific targeting of the murine BRCA2 breast cancer susceptibility gene in mice
NK Collins, KA McAllister, LM Bennett, K-U Wagner, T Ward, J Malphurs, G Goulding, EM Eddy, BJ Davis, RW Wiseman
Growth inhibition and growth stimulation by estradiol of estrogen receptor transfected human breast epithelial cell lines involve different pathways
BK Lundholt, P Briand, AE Lykkesfeldt
Hairy and enhancer of split homolog-1 (HES-1) mediates the proliferative effect of Beta-estradiol on breast cancer cell lines
A Ström, N Arai, J Leers, J-Å Gustafsson
Genetic variants of CYP19 (aromatase) and breast cancer risk
V Nedelcheva Kristensen, N Harada, N Yoshimura, E Haraldsen, PE Lønning, B Erikstein, R Kåresen, T Kristensen, A-L Børresen-Dale
The involvement of the MAPK signalling pathway in the adaptation of MCF-7 cells to long-term oestrogen deprivation
L-A Martin, CMW Chan, C Marshall, M Dowsett
IGFBP-7 expression in human breast cancer and association with proliferation and cell cycle aberrations
H Östlund, A Burger, A Seth, G Landberg
Activation of the Her2/neu receptor leads to antiestrogen resistance, but acquired resistance is not caused by altered ErbB expression and activation
SS Larsen, AE Lykkesfeldt
Factors modulating integrin Beta I expression on the breast cancer cell lines MCF-7 and MDA-MB-231
CJ Pogson, CMW Chan, L-A Martin, GPH Gui, M Dowsett
HER-2 activation and TP53 inactivation as predictors of survival in breast cancer
TI Andersen, E Skovlund, IK Bukholm, U Jacobsen, R Kåresen, B Erikstein, J Nesland, A-L Børresen-Dale
Role of the breast cancer susceptibility gene BRCA1 in radio-resistance
V Sylvain, Y-J Bignon
BRCA2 interacting proteins
H Vidarsson, E Mikaelsdottir, JE Eyfjörd, H Ögmundsdóttir, T Rafnar, S Valgeirsdóttir
Embryonic lethality in the Brca1-1700T mouse model suggests inhibition of p53-dependent pathways
P Hohenstein, M Kielman, C Breukel, P Krimpenfort, A Berns, M Bennett, R Wiseman, C Cornelisse, G-J van Ommen, P Devilee, R Fodde
The GSTT1 genotype is associated with p53 mutation status of breast cancer tumours
K Gudmundsdóttir, L Tryggvadóttir, JE Eyfjörd
Screening breast cancer patients for Norwegian ATM mutations
K Laake, P Vu, TI Andersen, B Erikstein, R Kåresen, PE Lønning, E Skovlund, A-L Børresen-Dale
Analysis of Fhit expression in stages of breast cancer progression
M Campiglio, G Somenzi, P Aiello, F Wärnberg, L Holmberg, CM Croce, S Menard
A detailed physical map of a region within human chromosome 16q22.1
E Frengen, P Rocca-Serra, S Shaposhnikov, L Taine, J Thorsen, C Bépoldin, M Longy, H Prydz, F Dorion-Bonnet
p16INK4A as a predictive factor in patients with locally advanced breast cancer treated with neoadjuvant doxorubicin monotherapy
S Geisler, B Smith-Sørensen, D Betticher, IK Bukholm, LA Akslen, A Kappeler, M Gugger, PE Lønning, A-L Børresen-Dale
Negative regulation of p53 expression is an essential, rate-limiting function of Jun in the control of cell cycle progression
M Schreiber, F Piu, A Kolbus, A Szabowski, U Möhle-Steinlein, J Tian, M Karin, P Angel, EF Wagner
Setting up an efficient and reliable screening method for novel c-Jun N-terminal kinase substrates
T Kallunki, C Holmberg, M Lerdrup-Hansen, T Herdegen, A Aronheim, M Jäättelä
Angiogenesis in breast cancer: establishing a link between angiogenesis and hormone regulation
R Soares, C Costa, F Gärtner, F Schmitt
AKT-1 and BCL-2 co-expression in breast cancer patients correlates with better survival
G Pérez-Tenorio, O Stål
Does a polymorphism in the CYP17 gene predict mammographic density?
G Ursin, SA Ingles, H Spencer Feigelson, GA Coetzee, L Bernstein, MC Pike, A Buley
Cytokeratin and mammaglobin as tumor markers in patients with high risk breast cancer
PF Ferrucci, C Rabascio, C Corsini, F Tealdo, M Paolucci, F Bertolini, H El Taani, G Martinelli
Promising method for DNA extraction from paraffin embedded archive material
A Bregård, P Vu, G Geitvik, A-L Børresen-Dale
Exact quantification of gene amplification in archival tissue sections by laser-assisted microdissection and real-time PCR
U Lehmann, S Glöckner, W Kleeberger, R von Wasielewski, H Kreipe
Screening for BRCA1 gene mutations by capillary electrophoretic REF-SSCP
P Kringen, HG Eiken, JC Pedersen, S Egedal, K Berg, KM Tveit, TI Andersen
Hypervariable area in the 5' flanking region of GSTP1, previously reported as a minisatellite repeat
V Nedelcheva Kristensen, T Kristensen, A-L Børresen-Dale
Comparative genomic hybridisation analysis of myoepithelial carcinoma of the breast
C Jones, MP Foschini, R Chaggar, Y-J Lu, D Wells, JM Shipley, V Eusebi, SR Lakhani
Transcript profiles and genotyping of cancer tissue
C Malmqvist, M Sievertzon, A Gustafsson, A Holmberg, M Larsson, A Alderborn, M Uhlén, J Lundeberg
Relation of gene expression-based tumor subclasses to clinical phenotypes
T Sørlie, CM Perou, PE Lønning, PO Brown, D Botstein, A-L Børresen-Dale
Molecular characteristics of inherited breast tumors
Å Borg, IA Hedenfalk, J Vallon-Christersson, N Loman, O Johannsson, H Olsson, DJ Duggan, Y Chen, M Bittner, O-P Kallioniemi, JM Trent
Estrogen receptors α and β in the rodent mammary gland
S Saji, EV Jensen, S Nilsson, T Rylander, M Warner, J-Å Gustafsson
Role of the ATM gene in radiation sensitivity, relevance to breast cancer treatment
J Hall, S Angèle, M Vuillaume, J-P Gérard, P Romestaing
Tumour-selective transcriptional targeting for breast cancer gene therapy
HC Hurst
G1/S control and its deregulation in cancer
J Bartek, C Lukas, C Sørensen, E Santoni-Rugiu, J Bartkova, J Lukas
Molecular control of apoptosis in the breast
C Streuli, A Gilmore, A Metcalfe, Y-J Lee, J Oliver, A Valentijn
Hypoxia and tumour angiogenesis involved in breast cancer progression and targets for therapy
AL Harris
Blood assays for earlier detection of cancers
AB Pardee, RJ Guan, HL Ford, MV Fournier, K Martin, R Sager
Tissue microarrays for high-throughput profiling in molecular oncology
O-P Kallioniemi, J Kononen, G Sauter
Two molecular cytogenetic views of breast cancer
J Gray, K Chin, C Collins, P Yaswin, G Nonet, D Kowbel, W-L Kuo, E Garcia, C Ortiz de Solorzano, D Knowles, S Lockett, M Bissell, V Weaver, D Pinkel, D Albertson, A-L Børresen-Dale, F Waldnian
Studying breast cancer on a genomic scale using DNA microarrays
D Botstein, PO Brown