Ausgabe 1/2012
Inhalt (46 Artikel)
Epithelial-mesenchymal transition, cancer stem cells and treatment resistance
Bhuvanesh Dave, Vivek Mittal, Nicholas M Tan, Jenny C Chang
Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed
Laura Stanbery, Elizabeth M Petty
Understanding the mechanisms of aromatase inhibitor resistance
William R Miller, Alexey A Larionov
Do fatty breasts increase or decrease breast cancer risk?
John A Shepherd, Karla Kerlikowske
The dynamic yin-yang interaction of CXCR4 and CXCR7 in breast cancer metastasis
Oriana E Hawkins, Ann Richmond
Do we need biomarkers to predict the benefit of adding adjuvant taxanes for treatment of breast cancer?
José Pérez-García, Javier Cortés
Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes
Rosalyn D Ferguson, Ruslan Novosyadlyy, Yvonne Fierz, Nyosha Alikhani, Hui Sun, Shoshana Yakar, Derek LeRoith
The role and function of cadherins in the mammary gland
Jennifer L Andrews, Alvin C Kim, Julie R Hens
Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity
Anders Sundqvist, Peter ten Dijke, Hans van Dam
No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density
Celine M Vachon, Jingmei Li, Christopher G Scott, Per Hall, Kamila Czene, Xianshu Wang, Jianjun Liu, Zachary S Fredericksen, David N Rider, Fang-Fang Wu, Janet E Olson, Julie M Cunningham, Kristen N Stevens, Thomas A Sellers, Shane V Pankratz, Fergus J Couch
Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer
Luciana P Schwab, Danielle L Peacock, Debeshi Majumdar, Jesse F Ingels, Laura C Jensen, Keisha D Smith, Richard C Cushing, Tiffany N Seagroves
MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells
Rosamaria Lappano, Maria Francesca Santolla, Marco Pupo, Maria Stefania Sinicropi, Anna Caruso, Camillo Rosano, Marcello Maggiolini
MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7
Seok-Jun Kim, Ji-Young Shin, Kang-Duck Lee, Young-Ki Bae, Ki Woong Sung, Seok Jin Nam, Kyung-Hee Chun
Effect of dietary patterns differing in carbohydrate and fat content on blood lipidand glucose profiles based on weight-loss success of breast-cancer survivors
Henry J Thompson, Scot M Sedlacek, Devchand Paul, Pamela Wolfe, John N McGinley, Mary C Playdon, Elizabeth A Daeninck, Sara N Bartels, Mark R Wisthoff
Expression of stem cell and epithelial-mesenchymal transition markers in primary breast cancer patients with circulating tumor cells
Sabine Kasimir-Bauer, Oliver Hoffmann, Diethelm Wallwiener, Rainer Kimmig, Tanja Fehm
The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation
Joseph P Garay, Bedri Karakas, Abde M Abukhdeir, David P Cosgrove, John P Gustin, Michaela J Higgins, Hiroyuki Konishi, Yuko Konishi, Josh Lauring, Morassa Mohseni, Grace M Wang, Danijela Jelovac, Ashani Weeraratna, Cheryl A Sherman Baust, Patrice J Morin, Antoun Toubaji, Alan Meeker, Angelo M De Marzo, Gloria Lewis, Andrea Subhawong, Pedram Argani, Ben H Park
Molecular profiling of patient-derived breast cancer xenografts
Fabien Reyal, Charlotte Guyader, Charles Decraene, Carlo Lucchesi, Nathalie Auger, Franck Assayag, Ludmilla De Plater, David Gentien, Marie-France Poupon, Paul Cottu, Patricia De Cremoux, Pierre Gestraud, Anne Vincent-Salomon, Jean-Jacques Fontaine, Sergio Roman-Roman, Olivier Delattre, Didier Decaudin, Elisabetta Marangoni
Breast cancer incidence and case fatality among 4.7 million women in relation to social and ethnic background: a population-based cohort study
Omid Beiki, Per Hall, Anders Ekbom, Tahereh Moradi
Trends in incidence and detection of advanced breast cancer at biennial screening mammography in The Netherlands: a population based study
Joost Nederend, Lucien EM Duijm, Adri C Voogd, Johanna H Groenewoud, Frits H Jansen, Marieke WJ Louwman
Breast cancer risk assessment with five independent genetic variants and two risk factors in Chinese women
Juncheng Dai, Zhibin Hu, Yue Jiang, Hao Shen, Jing Dong, Hongxia Ma, Hongbing Shen
Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers
Desheng Weng, Jeffrey H Penzner, Baizheng Song, Shigeo Koido, Stuart K Calderwood, Jianlin Gong
Validation of the Gail model for predicting individual breast cancer risk in a prospective nationwide study of 28,104 Singapore women
Wen Yee Chay, Whee Sze Ong, Puay Hoon Tan, Nicholas Qi Jie Leo, Gay Hui Ho, Chia Siong Wong, Kee Seng Chia, Khuan Yew Chow, MinHan Tan Sr, Peter Ang Sr
Progranulin (GP88) tumor tissue expression is associated with increased risk of recurrence in breast cancer patients diagnosed with estrogen receptor positive invasive ductal carcinoma
Ginette Serrero, Douglas M Hawkins, Binbin Yue, Olga Ioffe, Pablo Bejarano, Jeffrey T Phillips, Jonathan F Head, Robert L Elliott, Katherine R Tkaczuk, Andrew K Godwin, JoEllen Weaver, Wes E Kim
Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells
Anupam Kumar, Jia Xu, Bokyung Sung, Santosh Kumar, Dihua Yu, Bharat B Aggarwal, Kapil Mehta
Balancing harms and benefits of service mammography screening programs: a cohort study
Donella Puliti, Guido Miccinesi, Marco Zappa, Gianfranco Manneschi, Emanuele Crocetti, Eugenio Paci
Tibolone increases bone mineral density but also relapse in breast cancer survivors: LIBERATE trial bone substudy
Nigel J Bundred, Peter Kenemans, Cheng Har Yip, Matthias W Beckmann, Jean-Michel Foidart, Piero Sismondi, Bo von Schoultz, Rena Vassilopoulou-Sellin, Rachid El Galta, Eugenie Van Lieshout, Mirjam Mol-Arts, Juan Planellas, Ernst Kubista
Use of glucocorticoids and risk of breast cancer: a Danish population-based case-control study
Gitte Vrelits Sørensen, Deirdre P Cronin-Fenton, Henrik Toft Sørensen, Sinna Pilgaard Ulrichsen, Lars Pedersen, Timothy L Lash
Germline DNA copy number variation in familial and early-onset breast cancer
Ana CV Krepischi, Maria Isabel W Achatz, Erika MM Santos, Silvia S Costa, Bianca CG Lisboa, Helena Brentani, Tiago M Santos, Amanda Gonçalves, Amanda F Nóbrega, Peter L Pearson, Angela M Vianna-Morgante, Dirce M Carraro, Ricardo R Brentani, Carla Rosenberg
Assessment of circulating tumor cells and serum markers for progression-free survival prediction in metastatic breast cancer: a prospective observational study
François-Clément Bidard, David Hajage, Thomas Bachelot, Suzette Delaloge, Etienne Brain, Mario Campone, Paul Cottu, Philippe Beuzeboc, Emilie Rolland, Claire Mathiot, Jean-Yves Pierga
Premenopausal serum androgens and breast cancer risk: a nested case-control study
Anne Zeleniuch-Jacquotte, Yelena Afanasyeva, Rudolf Kaaks, Sabina Rinaldi, Stephanie Scarmo, Mengling Liu, Alan A Arslan, Paolo Toniolo, Roy E Shore, Karen L Koenig
Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement
Hatef Darabi, Kamila Czene, Wanting Zhao, Jianjun Liu, Per Hall, Keith Humphreys
STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas
Szeman Ruby Chan, William Vermi, Jingqin Luo, Laura Lucini, Charles Rickert, Amy M Fowler, Silvia Lonardi, Cora Arthur, Larry JT Young, David E Levy, Michael J Welch, Robert D Cardiff, Robert D Schreiber
Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker
Ida Johansson, Cecilia Nilsson, Pontus Berglund, Martin Lauss, Markus Ringnér, Håkan Olsson, Lena Luts, Edith Sim, Sten Thorstensson, Marie-Louise Fjällskog, Ingrid Hedenfalk
Modulation of CXCR3 ligand secretion by prostaglandin E2 and cyclooxygenase inhibitors in human breast cancer
Holger Bronger, Sara Kraeft, Ulrike Schwarz-Boeger, Claudia Cerny, Alexandra Stöckel, Stefanie Avril, Marion Kiechle, Manfred Schmitt
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2mutation carriers
Antonis C Antoniou, Karoline B Kuchenbaecker, Penny Soucy, Jonathan Beesley, Xiaoqing Chen, Lesley McGuffog, Andrew Lee, Daniel Barrowdale, Sue Healey, Olga M Sinilnikova, Maria A Caligo, Niklas Loman, Katja Harbst, Annika Lindblom, Brita Arver, Richard Rosenquist, Per Karlsson, Kate Nathanson, Susan Domchek, Tim Rebbeck, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Elżbieta Złowowcka-Perłowska, Ana Osorio, Mercedes Durán, Raquel Andrés, Javier Benítez, Ute Hamann, Frans B Hogervorst, Theo A van Os, Senno Verhoef, Hanne EJ Meijers-Heijboer, Juul Wijnen, Encarna B Gómez Garcia, Marjolijn J Ligtenberg, Mieke Kriege, J Margriet Collée, Margreet GEM Ausems, Jan C Oosterwijk, Susan Peock, Debra Frost, Steve D Ellis, Radka Platte, Elena Fineberg, D Gareth Evans, Fiona Lalloo, Chris Jacobs, Ros Eeles, Julian Adlard, Rosemarie Davidson, Trevor Cole, Jackie Cook, Joan Paterson, Fiona Douglas, Carole Brewer, Shirley Hodgson, Patrick J Morrison, Lisa Walker, Mark T Rogers, Alan Donaldson, Huw Dorkins, Andrew K Godwin, Betsy Bove, Dominique Stoppa-Lyonnet, Claude Houdayer, Bruno Buecher, Antoine de Pauw, Sylvie Mazoyer, Alain Calender, Mélanie Léoné, Brigitte Bressac- de Paillerets, Olivier Caron, Hagay Sobol, Marc Frenay, Fabienne Prieur, Sandra Fert Ferrer, Isabelle Mortemousque, Saundra Buys, Mary Daly, Alexander Miron, Mary Beth Terry, John L Hopper, Esther M John, Melissa Southey, David Goldgar, Christian F Singer, Anneliese Fink-Retter, Muy-Kheng Tea, Daphne Geschwantler Kaulich, Thomas VO Hansen, Finn C Nielsen, Rosa B Barkardottir, Mia Gaudet, Tomas Kirchhoff, Vijai Joseph, Ana Dutra-Clarke, Kenneth Offit, Marion Piedmonte, Judy Kirk, David Cohn, Jean Hurteau, John Byron, James Fiorica, Amanda E Toland, Marco Montagna, Cristina Oliani, Evgeny Imyanitov, Claudine Isaacs, Laima Tihomirova, Ignacio Blanco, Conxi Lazaro, Alex Teulé, J Del Valle, Simon A Gayther, Kunle Odunsi, Jenny Gross, Beth Y Karlan, Edith Olah, Soo-Hwang Teo, Patricia A Ganz, Mary S Beattie, Cecelia M Dorfling, Elizabeth Jansen van Rensburg, Orland Diez, Ava Kwong, Rita K Schmutzler, Barbara Wappenschmidt, Christoph Engel, Alfons Meindl, Nina Ditsch, Norbert Arnold, Simone Heidemann, Dieter Niederacher, Sabine Preisler-Adams, Dorothea Gadzicki, Raymonda Varon-Mateeva, Helmut Deissler, Andrea Gehrig, Christian Sutter, Karin Kast, Britta Fiebig, Dieter Schäfer, Trinidad Caldes, Miguel de la Hoya, Heli Nevanlinna, Taru A Muranen, Bernard Lespérance, Amanda B Spurdle, Susan L Neuhausen, Yuan C Ding, Xianshu Wang, Zachary Fredericksen, Vernon S Pankratz, Noralane M Lindor, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Bernardo Bonanni, Loris Bernard, Riccardo Dolcetti, Laura Papi, Laura Ottini, Paolo Radice, Mark H Greene, Jennifer T Loud, Irene L Andrulis, Hilmi Ozcelik, Anna Marie Mulligan, Gord Glendon, Mads Thomassen, Anne-Marie Gerdes, Uffe B Jensen, Anne-Bine Skytte, Torben A Kruse, Georgia Chenevix-Trench, Fergus J Couch, Jacques Simard, Douglas F Easton
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells
Jason A Sprowl, Kerry Reed, Stephen R Armstrong, Carita Lanner, Baoqing Guo, Irina Kalatskaya, Lincoln Stein, Stacey L Hembruff, Adam Tam, Amadeo M Parissenti
Contribution of CXCL12 secretion to invasion of breast cancer cells
Pamela J Boimel, Tatiana Smirnova, Zhen Ni Zhou, Jeffrey Wyckoff, Haein Park, Salvatore J Coniglio, Bin-Zhi Qian, E Richard Stanley, Dianne Cox, Jeffrey W Pollard, William J Muller, John Condeelis, Jeffrey E Segall
Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer
Mohammed A Aleskandarany, Andrew R Green, Ahmed A Benhasouna, Fabricio F Barros, Keith Neal, Jorge S Reis-Filho, Ian O Ellis, Emad A Rakha
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis
Arumugam Nagalingam, Jack L Arbiser, Michael Y Bonner, Neeraj K Saxena, Dipali Sharma
Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells
Kaiji Hu, Jennifer H Law, Abbas Fotovati, Sandra E Dunn
PIK3CAmutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups
Magdalena Cizkova, Aurélie Susini, Sophie Vacher, Géraldine Cizeron-Clairac, Catherine Andrieu, Keltouma Driouch, Emmanuelle Fourme, Rosette Lidereau, Ivan Bièche
Phospho-ibuprofen (MDC-917) suppresses breast cancer growth: an effect controlled by the thioredoxin system
Yu Sun, Leahana M Rowehl, Liqun Huang, Gerardo G Mackenzie, Kvetoslava Vrankova, Despina Komninou, Basil Rigas
Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
Eleni van Schooneveld, Maartje CA Wouters, Ilse Van der Auwera, Dieter J Peeters, Hans Wildiers, Peter A Van Dam, Ignace Vergote, Peter B Vermeulen, Luc Y Dirix, Steven J Van Laere
Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo
Hicham Lahlou, Virginie Sanguin-Gendreau, Margaret C Frame, William J Muller
Needles in a haystack: finding recurrent genomic changes in breast cancer
Justin Cidado, Julia A Beaver, Ben Ho Park