Ausgabe 1/2014
Inhalt (29 Artikel)
Targeting RET–interleukin-6 crosstalk to impair metastatic dissemination in breast cancer
Andrea Morandi, Clare M Isacke
Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity?
Jeffrey M Rosen, Kevin Roarty
Vaccines against human HER2 prevent mammary carcinoma in mice transgenic for human HER2
Carla De Giovanni, Giordano Nicoletti, Elena Quaglino, Lorena Landuzzi, Arianna Palladini, Marianna Lucia Ianzano, Massimiliano Dall’Ora, Valentina Grosso, Dario Ranieri, Roberta Laranga, Stefania Croci, Augusto Amici, Manuel L Penichet, Manuela Iezzi, Federica Cavallo, Patrizia Nanni, Pier-Luigi Lollini
Significant overlap between human genome-wide association-study nominated breast cancer risk alleles and rat mammary cancer susceptibility loci
Jennifer Sanders, David J Samuelson
Individual xenograft as a personalized therapeutic resort for women with metastatic triple-negative breast carcinoma
Guilhem Bousquet, Jean-Paul Feugeas, Irmine Ferreira, Laetitia Vercellino, Nathalie Jourdan, Philippe Bertheau, Cédric de Bazelaire, Emmanuel Barranger, Anne Janin
Phosphorylated p-70S6K predicts tamoxifen resistance in postmenopausal breast cancer patients randomized between adjuvant tamoxifen versus no systemic treatment
Karin Beelen, Mark Opdam, Tesa M Severson, Rutger HT Koornstra, Andrew D Vincent, Jelle Wesseling, Jettie J Muris, Els MJJ Berns, Jan B Vermorken, Paul J van Diest, Sabine C Linn
Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide
Dawn R Cochrane, Sebastián Bernales, Britta M Jacobsen, Diana M Cittelly, Erin N Howe, Nicholas C D’Amato, Nicole S Spoelstra, Susan M Edgerton, Annie Jean, Javier Guerrero, Francisco Gómez, Satyanarayana Medicherla, Iván E Alfaro, Emma McCullagh, Paul Jedlicka, Kathleen C Torkko, Ann D Thor, Anthony D Elias, Andrew A Protter, Jennifer K Richer
Direct inhibition of PI3K in combination with dual HER2 inhibitors is required for optimal antitumor activity in HER2+ breast cancer cells
Brent N Rexer, Siprachanh Chanthaphaychith, Kimberly Brown Dahlman, Carlos L Arteaga
Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study
Danielle H Bodicoat, Minouk J Schoemaker, Michael E Jones, Emily McFadden, James Griffin, Alan Ashworth, Anthony J Swerdlow
A potential mechanism for extracellular matrix induction of breast cancer cell normality
Robert D Bruno, Gilbert H Smith
Clinical development of mTOR inhibitors in breast cancer
Cecile Vicier, Maria Vittoria Dieci, Monica Arnedos, Suzette Delaloge, Patrice Viens, Fabrice Andre
Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial
Vivien HC Bramwell, Alan B Tuck, Judith-Anne W Chapman, Pieter H Anborgh, Carl O Postenka, Waleed Al-Katib, Lois E Shepherd, Lei Han, Carolyn F Wilson, Kathleen I Pritchard, Michael N Pollak, Ann F Chambers
Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression
Trisha Rao, Jill J Ranger, Harvey W Smith, Sonya H Lam, Lewis Chodosh, William J Muller
Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro
Nicola J Jordan, Carol M Dutkowski, Denise Barrow, Huw J Mottram, Iain R Hutcheson, Robert I Nicholson, Sylvie M Guichard, Julia MW Gee
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Tomasz K Wojdacz, Johanne A Windeløv, Britta B Thestrup, Tine E Damsgaard, Jens Overgaard, Lise Lotte Hansen
Immune approaches to the treatment of breast cancer, around the corner?
Carmen Criscitiello, Angela Esposito, Lucia Gelao, Luca Fumagalli, Marzia Locatelli, Ida Minchella, Laura Adamoli, Aron Goldhirsch, Giuseppe Curigliano
PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin-like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients
Karin Beelen, Mark Opdam, Tesa M Severson, Rutger HT Koornstra, Andrew D Vincent, Jelle Wesseling, Jettie J Muris, Els MJJ Berns, Jan B Vermorken, Paul J van Diest, Sabine C Linn
Nonhypoxic regulation and role of hypoxia-inducible factor 1 in aromatase inhibitor resistant breast cancer
Armina A Kazi, Rabia A Gilani, Amanda J Schech, Saranya Chumsri, Gauri Sabnis, Preeti Shah, Olga Goloubeva, Shari Kronsberg, Angela H Brodie
A novel mechanism of regulating breast cancer cell migration via palmitoylation-dependent alterations in the lipid raft affiliation of CD44
Irina S Babina, Elaine A McSherry, Simona Donatello, Arnold DK Hill, Ann M Hopkins
Dickkopf-1 is regulated by the mevalonate pathway in breast cancer
Tilman D Rachner, Andy Göbel, Stefanie Thiele, Martina Rauner, Peggy Benad-Mehner, Peyman Hadji, Thomas Bauer, Michael H Muders, Gustavo B Baretton, Franz Jakob, Regina Ebert, Martin Bornhäuser, Christian Schem, Lorenz C Hofbauer
Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines
Pietro Rizza, Ines Barone, Domenico Zito, Francesca Giordano, Marilena Lanzino, Francesca De Amicis, Loredana Mauro, Diego Sisci, Stefania Catalano, Karin Dahlman Wright, Jan-ake Gustafsson, Sebastiano Andò
Parity-related molecular signatures and breast cancer subtypes by estrogen receptor status
Melissa Rotunno, Xuezheng Sun, Jonine Figueroa, Mark E Sherman, Montserrat Garcia-Closas, Paul Meltzer, Tyisha Williams, Sallie Smith Schneider, D Joseph Jerry, Xiaohong R Yang, Melissa A Troester
PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data
Dimitrios Zardavas, Wayne A Phillips, Sherene Loi
New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells
Ted H-T Chang, Kamini Kunasegaran, Gerard A Tarulli, Duvini De Silva, P Mathijs Voorhoeve, Alexandra M Pietersen
Pregnancy-associated breast cancers are driven by differences in adipose stromal cells present during lactation
Jessica McCready, Lisa M Arendt, Eugene Glover, Vandana Iyer, Jerrica L Briendel, Stephen R Lyle, Stephen P Naber, Daniel G Jay, Charlotte Kuperwasser
Tumor phenotype and breast density in distinct categories of interval cancer: results of population-based mammography screening in Spain
Laia Domingo, Dolores Salas, Raquel Zubizarreta, Marisa Baré, Garbiñe Sarriugarte, Teresa Barata, Josefa Ibáñez, Jordi Blanch, Montserrat Puig-Vives, Ana Belén Fernández, Xavier Castells, Maria Sala
Birth weight, childhood body mass index, and height in relation to mammographic density and breast cancer: a register-based cohort study
Zorana J Andersen, Jennifer L Baker, Kristine Bihrmann, Ilse Vejborg, Thorkild IA Sørensen, Elsebeth Lynge
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
Maria T Grinde, Nirma Skrbo, Siver A Moestue, Einar A Rødland, Eldrid Borgan, Alexandr Kristian, Beathe Sitter, Tone F Bathen, Anne-Lise Børresen-Dale, Gunhild M Mælandsmo, Olav Engebraaten, Therese Sørlie, Elisabetta Marangoni, Ingrid S Gribbestad
Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells
Manish Tandon, Zujian Chen, Jitesh Pratap