Skip to main content
main-content

Zeitschrift

Breast Cancer Research

Breast Cancer Research 1/2020

Ausgabe 1/2020

Inhaltsverzeichnis ( 94 Artikel )

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer

Lori J. Goldstein, Raymond P. Perez, Denise Yardley, Linda K. Han, James M. Reuben, Hui Gao, Susan McCanna, Beth Butler, Pier Adelchi Ruffini, Yi Liu, Roberto R. Rosato, Jenny C. Chang

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Identification and transfer of spatial transcriptomics signatures for cancer diagnosis

Niyaz Yoosuf, José Fernández Navarro, Fredrik Salmén, Patrik L. Ståhl, Carsten O. Daub

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

p66ShcA functions as a contextual promoter of breast cancer metastasis

Kyle Lewis, Alex Kiepas, Jesse Hudson, Julien Senecal, Jacqueline R. Ha, Elena Voorand, Matthew G. Annis, Valerie Sabourin, Ryuhjin Ahn, Rachel La Selva, Sébastien Tabariès, Brian E. Hsu, Matthew J. Siegel, Matthew Dankner, Eduardo Cepeda Canedo, Mathieu Lajoie, Ian R. Watson, Claire M. Brown, Peter M. Siegel, Josie Ursini-Siegel

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. Van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton, GENEPSO, EMBRACE, HEBON, kConFab Investigators, on behalf of IBCCS, kConFab, BCFR

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: NSABP FB-7: a phase II randomized neoadjuvant trial with paclitaxel + trastuzumab and/or neratinib followed by chemotherapy and postoperative trastuzumab in HER2+ breast cancer

Samuel A. Jacobs, André Robidoux, Jame Abraham, José Manuel Pérez-Garcia, Nicla La Verde, James M. Orcutt, Marina E. Cazzaniga, Fanny Piette, Silvia Antolín, Elena Aguirre, Javier Cortes, Antonio Llombart-Cussac, Serena Di Cosimo, Rim S. Kim, Huichen Feng, Corey Lipchik, Peter C. Lucas, Ashok Srinivasan, Ying Wang, Nan Song, Patrick G. Gavin, April D. Balousek, Soonmyung Paik, Carmen J. Allegra, Norman Wolmark, Katherine L. Pogue-Geile

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Long-term risk of ischemic heart disease after adjuvant radiotherapy in breast cancer: results from a large population-based cohort

Anna-Karin Wennstig, Charlotta Wadsten, Hans Garmo, Irma Fredriksson, Carl Blomqvist, Lars Holmberg, Greger Nilsson, Malin Sund

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Serum exosomal-annexin A2 is associated with African-American triple-negative breast cancer and promotes angiogenesis

Pankaj Chaudhary, Lee D. Gibbs, Sayantan Maji, Cheryl M. Lewis, Sumihiro Suzuki, Jamboor K. Vishwanatha

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

A deep learning image-based intrinsic molecular subtype classifier of breast tumors reveals tumor heterogeneity that may affect survival

Mustafa I. Jaber, Bing Song, Clive Taylor, Charles J. Vaske, Stephen C. Benz, Shahrooz Rabizadeh, Patrick Soon-Shiong, Christopher W. Szeto

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review

Tim C. de Ruijter, Frank van der Heide, Kim M. Smits, Maureen J. Aarts, Manon van Engeland, Vivianne C. G. Heijnen

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

Sunil Pancholi, Mariana Ferreira Leal, Ricardo Ribas, Nikiana Simigdala, Eugene Schuster, Sophie Chateau-Joubert, Lila Zabaglo, Margaret Hills, Andrew Dodson, Qiong Gao, Stephen R. Johnston, Mitch Dowsett, Sabina C. Cosulich, Elisabetta Marangoni, Lesley-Ann Martin

01.12.2020 | Review | Ausgabe 1/2020 Open Access

HER2 heterogeneity and resistance to anti-HER2 antibody-drug conjugates

Alberto Ocaña, Eitan Amir, Atanasio Pandiella

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis

Adi Zundelevich, Maya Dadiani, Smadar Kahana-Edwin, Amit Itay, Tal Sella, Moran Gadot, Karen Cesarkas, Sarit Farage-Barhom, Efrat Glick Saar, Eran Eyal, Nitzan Kol, Anya Pavlovski, Nora Balint-Lahat, Daniela Dick-Necula, Iris Barshack, Bella Kaufman, Einav Nili Gal-Yam

01.12.2020 | Letter | Ausgabe 1/2020 Open Access

Letter to the editor: a response to Ming’s study on machine learning techniques for personalized breast cancer risk prediction

Daniele Giardiello, Antonis C. Antoniou, Luigi Mariani, Douglas F. Easton, Ewout W. Steyerberg

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtype

Adana A. M. Llanos, Yong Lin, Wenjin Chen, Song Yao, Jorden Norin, Marina A. Chekmareva, Coral Omene, Lei Cong, Angela R. Omilian, Thaer Khoury, Chi-Chen Hong, Shridar Ganesan, David J. Foran, Michael Higgins, Christine B. Ambrosone, Elisa V. Bandera, Kitaw Demissie

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study

Danielle H. Bodicoat, Minouk J. Schoemaker, Michael E. Jones, Emily McFadden, James Griffin, Alan Ashworth, Anthony J. Swerdlow

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field

Tatiane Yanes, Mary-Anne Young, Bettina Meiser, Paul A. James

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer

Christos Vaklavas, Brian S. Roberts, Katherine E. Varley, Nancy U. Lin, Minetta C. Liu, Hope S. Rugo, Shannon Puhalla, Rita Nanda, Anna Maria Storniolo, Lisa A. Carey, Mansoor N. Saleh, Yufeng Li, Jennifer F. Delossantos, William E. Grizzle, Albert F. LoBuglio, Richard M. Myers, Andres Forero-Torres, on behalf of the Translational Breast Cancer Research Consortium (TBCRC)

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Circulating 27-hydroxycholesterol and breast cancer tissue expression of CYP27A1, CYP7B1, LXR-β, and ERβ: results from the EPIC-Heidelberg cohort

Charlotte Le Cornet, Britta Walter, Disorn Sookthai, Theron S. Johnson, Tilman Kühn, Ester Herpel, Rudolf Kaaks, Renée T. Fortner

01.12.2020 | Letter | Ausgabe 1/2020 Open Access

Lower vitamin D status may help explain why black women have a higher risk of invasive breast cancer than white women

William B. Grant

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. Van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton, GENEPSO, EMBRACE, HEBON, kConFab Investigators, on behalf of IBCCS, kConFab and BCFR

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth

Miao Li, Meng Pan, Chengzhong You, Fengshu Zhao, Di Wu, Mei Guo, Hui Xu, Fangfang Shi, Danfeng Zheng, Jun Dou

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Hematologic adverse events following palbociclib dose reduction in patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer: pooled analysis from randomized phase 2 and 3 studies

Johannes Ettl, Seock-Ah Im, Jungsil Ro, Norikazu Masuda, Marco Colleoni, Patrick Schnell, Eustratios Bananis, Dongrui R. Lu, Massimo Cristofanilli, Hope S. Rugo, Richard S. Finn

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis

Adi Zundelevich, Maya Dadiani, Smadar Kahana-Edwin, Amit Itay, Tal Sella, Moran Gadot, Karen Cesarkas, Sarit Farage-Barhom, Efrat Glick Saar, Eran Eyal, Nitzan Kol, Anya Pavlovski, Nora Balint-Lahat, Daniela Dick-Necula, Iris Barshack, Bella Kaufman, Einav Nili Gal-Yam

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Diffuse optical spectroscopic imaging reveals distinct early breast tumor hemodynamic responses to metronomic and maximum tolerated dose regimens

Anup Tank, Hannah M. Peterson, Vivian Pera, Syeda Tabassum, Anais Leproux, Thomas O’Sullivan, Eric Jones, Howard Cabral, Naomi Ko, Rita S. Mehta, Bruce J. Tromberg, Darren Roblyer

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

High hepatocyte growth factor expression in primary tumor predicts better overall survival in male breast cancer

Si-Qi Qiu, Johan van Rooijen, Hilde H. Nienhuis, Bert van der Vegt, Hetty Timmer-Bosscha, Elise van Leeuwen-Stok, Annemiek M. E. Walenkamp, Carolien H. M. van Deurzen, Geertruida H. de Bock, Elisabeth G. E. de Vries, Carolien P. Schröder

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Serum exosomal-annexin A2 is associated with African-American triple-negative breast cancer and promotes angiogenesis

Pankaj Chaudhary, Lee D. Gibbs, Sayantan Maji, Cheryl M. Lewis, Sumihiro Suzuki, Jamboor K. Vishwanatha

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast

Milim Kim, Yul Ri Chung, Hyun Jeong Kim, Ji Won Woo, Soomin Ahn, So Yeon Park

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Everolimus versus alpelisib in advanced hormone receptor-positive HER2-negative breast cancer: targeting different nodes of the PI3K/AKT/mTORC1 pathway with different clinical implications

Claudio Vernieri, Francesca Corti, Federico Nichetti, Francesca Ligorio, Sara Manglaviti, Emma Zattarin, Carmen G. Rea, Giuseppe Capri, Giulia V. Bianchi, Filippo de Braud

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment

Marie-Therese Haider, Hiroaki Saito, Jennifer Zarrer, Kevin Uzhunnumpuram, Sankari Nagarajan, Vijayalakshmi Kari, Michael Horn-Glander, Stefan Werner, Eric Hesse, Hanna Taipaleenmäki

01.12.2020 | Letter | Ausgabe 1/2020 Open Access

Letter to the editor: Response to Giardiello D, Antoniou AC, Mariani L, Easton DF, Steyerberg EW

Chang Ming, Valeria Viassolo, Nicole Probst-Hensch, Pierre O. Chappuis, Ivo D. Dinov, Maria C. Katapodi

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Tumor sequencing is useful to refine the analysis of germline variants in unexplained high-risk breast cancer families

Cédric Van Marcke, Raphaël Helaers, Anne De Leener, Ahmad Merhi, Céline A. Schoonjans, Jérôme Ambroise, Christine Galant, Paul Delrée, Françoise Rothé, Isabelle Bar, Elsa Khoury, Pascal Brouillard, Jean-Luc Canon, Peter Vuylsteke, Jean-Pascal Machiels, Martine Berlière, Nisha Limaye, Miikka Vikkula, François P. Duhoux

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer

Brooke N. McKnight, Seongho Kim, Julie L. Boerner, Nerissa T. Viola

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Apolipoprotein-mediated regulation of lipid metabolism induces distinctive effects in different types of breast cancer cells

Céline Ben Hassen, Jorge L. Gutierrez-Pajares, Cyrille Guimaraes, Roseline Guibon, Michelle Pinault, Gaëlle Fromont, Philippe G. Frank

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer

Carlos Perez Kerkvliet, Amy R. Dwyer, Caroline H. Diep, Robert H. Oakley, Christopher Liddle, John A. Cidlowski, Carol A. Lange

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Insulin resistance contributes to racial disparities in breast cancer prognosis in US women

Emily J. Gallagher, Kezhen Fei, Sheldon M. Feldman, Elisa Port, Neil B. Friedman, Susan K. Boolbol, Brigid Killelea, Melissa Pilewskie, Lydia Choi, Tari King, Anupma Nayak, Rebeca Franco, Daliz Cruz, Irini M. Antoniou, Derek LeRoith, Nina A. Bickell

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness

Clarissa Wormsbaecher, Andrea R. Hindman, Alex Avendano, Marcos Cortes-Medina, Caitlin E. Jones, Andrew Bushman, Lotanna Onua, Claire E. Kovalchin, Alina R. Murphy, Hannah L. Helber, Ali Shapiro, Kyle Voytovitch, Xingyan Kuang, Renan Aguilar-Valenzuela, Jennifer L. Leight, Jonathan W. Song, Craig J. Burd

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Quantitative stain-free imaging and digital profiling of collagen structure reveal diverse survival of triple negative breast cancer patients

Laurent Gole, Joe Yeong, Jeffrey Chun Tatt Lim, Kok Haur Ong, Hao Han, Aye Aye Thike, Yong Cheng Poh, Sidney Yee, Jabed Iqbal, Wanjin Hong, Bernett Lee, Weimiao Yu, Puay Hoon Tan

01.12.2020 | Short report | Ausgabe 1/2020 Open Access

Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay

Nirmala Sirisena, Kajal Biswas, Teresa Sullivan, Stacey Stauffer, Linda Cleveland, Eileen Southon, Vajira H. W. Dissanayake, Shyam K. Sharan

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Investigation of the adolescent female breast transcriptome and the impact of obesity

Adam Burkholder, Dennis Akrobetu, Arun R. Pandiri, Kiki Ton, Sue Kim, Brian I. Labow, Laura C. Nuzzi, Joseph M. Firriolo, Sallie S. Schneider, Suzanne E. Fenton, Natalie D. Shaw

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Frequency and spectrum of PIK3CA somatic mutations in breast cancer

Olga Martínez-Sáez, Nuria Chic, Tomás Pascual, Barbara Adamo, Maria Vidal, Blanca González-Farré, Esther Sanfeliu, Francesco Schettini, Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez, Débora Martínez, Patricia Galván, Ana Belén Rodríguez, Antonio Martinez, Montserrat Muñoz, Aleix Prat

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial

Signe Korsgaard Skriver, Maj-Britt Jensen, Ann Soegaard Knoop, Bent Ejlertsen, Anne-Vibeke Laenkholm

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Association of TILs with clinical parameters, Recurrence Score® results, and prognosis in patients with early HER2-negative breast cancer (BC)—a translational analysis of the prospective WSG PlanB trial

Cornelia Kolberg-Liedtke, Oleg Gluz, Fred Heinisch, Friedrich Feuerhake, Hans Kreipe, Michael Clemens, Benno Nuding, Wolfram Malter, Toralf Reimer, Rachel Wuerstlein, Monika Graeser, Steve Shak, Ulrike Nitz, Ronald Kates, Matthias Christgen, Nadia Harbeck

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs

Tejaswini P. Reddy, Dong S. Choi, Ann C. Anselme, Wei Qian, Wen Chen, Johan Lantto, Ivan D. Horak, Michael Kragh, Jenny C. Chang, Roberto R. Rosato

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients

Mysoon M. Al-Ansari, Maher Al-Saif, Maria Arafah, Abdelmonneim M. Eldali, Asma Tulbah, Taher Al-Tweigeri, Abdelhabib Semlali, Khalid S. Khabar, Abdelilah Aboussekhra

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

ERα-36 regulates progesterone receptor activity in breast cancer

Henri-Philippe Konan, Loay Kassem, Soleilmane Omarjee, Ausra Surmieliova-Garnès, Julien Jacquemetton, Elodie Cascales, Amélie Rezza, Olivier Trédan, Isabelle Treilleux, Coralie Poulard, Muriel Le Romancer

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer

Swaathi Jayaraman, Xiaonan Hou, Mary J. Kuffel, Vera J. Suman, Tanya L. Hoskin, Kathryn E. Reinicke, David G. Monroe, Krishna R. Kalari, Xiaojia Tang, Megan A. Zeldenrust, Jingfei Cheng, Elizabeth S. Bruinsma, Sarah A. Buhrow, Renee M. McGovern, Stephanie L. Safgren, Chad A. Walden, Jodi M. Carter, Joel M. Reid, James N. Ingle, Matthew M. Ames, John R. Hawse, Matthew P. Goetz

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer

Lori J. Goldstein, Raymond P. Perez, Denise Yardley, Linda K. Han, James M. Reuben, Hui Gao, Susan McCanna, Beth Butler, Pier Adelchi Ruffini, Yi Liu, Roberto R. Rosato, Jenny C. Chang

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Modeling the natural history of ductal carcinoma in situ based on population data

Sarocha Chootipongchaivat, Nicolien T. van Ravesteyn, Xiaoxue Li, Hui Huang, Harald Weedon-Fekjær, Marc D. Ryser, Donald L. Weaver, Elizabeth S. Burnside, Brandy M. Heckman-Stoddard, Harry J. de Koning, Sandra J. Lee

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Efficacy of neoadjuvant endocrine therapy compared with neoadjuvant chemotherapy in pre-menopausal patients with oestrogen receptor-positive and HER2-negative, lymph node-positive breast cancer

Hee Jeong Kim, Woo Chul Noh, Eun Sook Lee, Yong Sik Jung, Lee Su Kim, Wonshik Han, Seok Jin Nam, Gyung -Yub Gong, Hwa Jung Kim, Sei Hyun Ahn

28.05.2020 | COVID-19 | Research article | Ausgabe 1/2020 Open Access

COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris area

Perrine Vuagnat, Maxime Frelaut, Toulsie Ramtohul, Clémence Basse, Sarah Diakite, Aurélien Noret, Audrey Bellesoeur, Vincent Servois, Delphine Hequet, Enora Laas, Youlia Kirova, Luc Cabel, Jean-Yves Pierga, Laurence Bozec, Xavier Paoletti, Paul Cottu, François-Clément Bidard, Institut Curie Breast Cancer and COVID Group

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Risk of early progression according to circulating ESR1 mutation, CA-15.3 and cfDNA increases under first-line anti-aromatase treatment in metastatic breast cancer

Florian Clatot, Anne Perdrix, Ludivine Beaussire, Justine Lequesne, Christelle Lévy, George Emile, Michael Bubenheim, Sigrid Lacaille, Céline Calbrix, Laetitia Augusto, Cécile Guillemet, Cristina Alexandru, Maxime Fontanilles, David Sefrioui, Lucie Burel, Sabine Guénot, Doriane Richard, Nasrin Sarafan-Vasseur, Frédéric Di Fiore

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

A machine learning model that classifies breast cancer pathologic complete response on MRI post-neoadjuvant chemotherapy

Elizabeth J. Sutton, Natsuko Onishi, Duc A. Fehr, Brittany Z. Dashevsky, Meredith Sadinski, Katja Pinker, Danny F. Martinez, Edi Brogi, Lior Braunstein, Pedram Razavi, Mahmoud El-Tamer, Virgilio Sacchini, Joseph O. Deasy, Elizabeth A. Morris, Harini Veeraraghavan

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Ultrafast dynamic contrast-enhanced breast MRI may generate prognostic imaging markers of breast cancer

Natsuko Onishi, Meredith Sadinski, Mary C. Hughes, Eun Sook Ko, Peter Gibbs, Katherine M. Gallagher, Maggie M. Fung, Theodore J. Hunt, Danny F. Martinez, Amita Shukla-Dave, Elizabeth A. Morris, Elizabeth J. Sutton

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

Ritama Paul, Ming Luo, Xueying Mo, Jason Lu, Syn Kok Yeo, Jun-Lin Guan

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer

Brock A. Humphries, Alyssa C. Cutter, Johanna M. Buschhaus, Yu-Chih Chen, Tonela Qyli, Dilrukshika S. W. Palagama, Samantha Eckley, Tanner H. Robison, Avinash Bevoor, Benjamin Chiang, Henry R. Haley, Saswat Sahoo, Phillip C. Spinosa, Dylan B. Neale, Jagadish Boppisetti, Debashis Sahoo, Pradipta Ghosh, Joerg Lahann, Brian D. Ross, Eusik Yoon, Kathryn E. Luker, Gary D. Luker

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Triple-negative breast cancer molecular subtyping and treatment progress

Li Yin, Jiang-Jie Duan, Xiu-Wu Bian, Shi-cang Yu

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Racial differences in CD8+ T cell infiltration in breast tumors from Black and White women

Yara Abdou, Kristopher Attwood, Ting-Yuan David Cheng, Song Yao, Elisa V. Bandera, Gary R. Zirpoli, Rochelle Payne Ondracek, Leighton Stein, Wiam Bshara, Thaer Khoury, Christine B. Ambrosone, Angela R. Omilian

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

Laura A. Baker, Holly Holliday, Daniel Roden, Christoph Krisp, Sunny Z. Wu, Simon Junankar, Aurelien A. Serandour, Hisham Mohammed, Radhika Nair, Geetha Sankaranarayanan, Andrew M. K. Law, Andrea McFarland, Peter T. Simpson, Sunil Lakhani, Eoin Dodson, Christina Selinger, Lyndal Anderson, Goli Samimi, Neville F. Hacker, Elgene Lim, Christopher J. Ormandy, Matthew J. Naylor, Kaylene Simpson, Iva Nikolic, Sandra O’Toole, Warren Kaplan, Mark J. Cowley, Jason S. Carroll, Mark Molloy, Alexander Swarbrick

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Age-associated genes in human mammary gland drive human breast cancer progression

Xiang Gu, Bingzhi Wang, Haiyan Zhu, You Zhou, Aaron M. Horning, Tim H-M Huang, Yidong Chen, Peter Houghton, Zhao Lai, Joel E. Michalek, Lu-Zhe Sun

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Detection of crown-like structures in breast adipose tissue and clinical outcomes among African-American and White women with breast cancer

Maret L. Maliniak, Aswathy Miriam Cheriyan, Mark E. Sherman, Yuan Liu, Keerthi Gogineni, Jiaqi Liu, Jiabei He, Uma Krishnamurti, Jasmine Miller-Kleinhenz, Ryan Ashiqueali, Jinjing He, Rami Yacoub, Lauren E. McCullough

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

KLF4 defines the efficacy of the epidermal growth factor receptor inhibitor, erlotinib, in triple-negative breast cancer cells by repressing the EGFR gene

Melyssa S. Roberts, Lindsey J. Anstine, Viviane S. Finke, Benjamin L. Bryson, Bryan M. Webb, Kristen L. Weber-Bonk, Darcie D. Seachrist, Parth R. Majmudar, Ruth A. Keri

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer

Malin Bergqvist, Karin Elebro, Malte Sandsveden, Signe Borgquist, Ann H. Rosendahl

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

New generation breast cancer cell lines developed from patient-derived xenografts

Jessica Finlay-Schultz, Britta M. Jacobsen, Duncan Riley, Kiran V. Paul, Scott Turner, Andrea Ferreira-Gonzalez, J. Chuck Harrell, Peter Kabos, Carol A. Sartorius

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Comparison of three scoring methods using the FDA-approved 22C3 immunohistochemistry assay to evaluate PD-L1 expression in breast cancer and their association with clinicopathologic factors

Hua Guo, Qingqing Ding, Yun Gong, Michael Z. Gilcrease, Min Zhao, Jun Zhao, Dawen Sui, Yun Wu, Hui Chen, Hui Liu, Jinxia Zhang, Erika Resetkova, Stacy L. Moulder, Wei-Lien Wang, Lei Huo

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology

Martin Blohmer, Li Zhu, Jennifer M. Atkinson, Sushil Beriwal, Joshua L. Rodríguez-López, Margaret Rosenzweig, Adam M. Brufsky, George Tseng, Peter C. Lucas, Adrian V. Lee, Steffi Oesterreich, Rachel C. Jankowitz

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

Ritama Paul, Ming Luo, Xueying Mo, Jason Lu, Syn Kok Yeo, Jun-Lin Guan

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

PRKCQ inhibition enhances chemosensitivity of triple-negative breast cancer by regulating Bim

Jessica H. Byerly, Elisa R. Port, Hanna Y. Irie

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration

Thilde Terkelsen, Francesco Russo, Pavel Gromov, Vilde Drageset Haakensen, Søren Brunak, Irina Gromova, Anders Krogh, Elena Papaleo

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Superior breast cancer metastasis risk stratification using an epithelial-mesenchymal-amoeboid transition gene signature

Amin Emad, Tania Ray, Tor W. Jensen, Meera Parat, Rachael Natrajan, Saurabh Sinha, Partha S. Ray

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression

Hannah Asperger, Nadia Stamm, Berthold Gierke, Michael Pawlak, Ute Hofmann, Ulrich M. Zanger, Annamaria Marton, Robert L. Katona, Andrea Buhala, Csaba Vizler, Jan-Philipp Cieslik, Eugen Ruckhäberle, Dieter Niederacher, Tanja Fehm, Hans Neubauer, Marina Ludescher

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

A subset of activated fibroblasts is associated with distant relapse in early luminal breast cancer

Claire Bonneau, Antoine Eliès, Yann Kieffer, Brigitte Bourachot, Sylvain Ladoire, Floriane Pelon, Delphine Hequet, Jean-Marc Guinebretière, Christophe Blanchet, Anne Vincent-Salomon, Roman Rouzier, Fatima Mechta-Grigoriou

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Neoadjuvant endocrine therapy in locally advanced estrogen or progesterone receptor-positive breast cancer: determining the optimal endocrine agent and treatment duration in postmenopausal women—a literature review and proposed guidelines

Lauren I. Madigan, Phuong Dinh, J. Dinny Graham

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Erythrocyte membrane fatty acids and breast cancer risk by tumor tissue expression of immuno-inflammatory markers and fatty acid synthase: a nested case-control study

Emma E. McGee, Claire H. Kim, Molin Wang, Donna Spiegelman, Daniel G. Stover, Yujing J. Heng, Laura C. Collins, Gabrielle M. Baker, Maryam S. Farvid, Pepper Schedin, Sonali Jindal, Rulla M. Tamimi, A. Heather Eliassen

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer

Esther H. Lips, Anne Benard-Slagter, Mark Opdam, Caroline E. Scheerman, Jelle Wesseling, Frans B. L. Hogervorst, Sabine C. Linn, Suvi Savola, Petra M. Nederlof

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Identification and targeting of selective vulnerability rendered by tamoxifen resistance

Madhurendra Singh, Xiaolei Zhou, Xinsong Chen, Gema Sanz Santos, Sylvain Peuget, Qing Cheng, Ali Rihani, Elias S. J. Arnér, Johan Hartman, Galina Selivanova

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population

Taekyu Kang, Christina Yau, Christopher K. Wong, John Z. Sanborn, Yulia Newton, Charlie Vaske, Stephen C. Benz, Gregor Krings, Roman Camarda, Jill E. Henry, Josh Stuart, Mark Powell, Christopher C. Benz

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Distinct phenotypes of cancer cells on tissue matrix gel

Kelsey F. Ruud, William C. Hiscox, Ilhan Yu, Roland K. Chen, Weimin Li

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

EFFECT: a randomized phase II study of efficacy and impact on function of two doses of nab-paclitaxel as first-line treatment in older women with advanced breast cancer

Laura Biganzoli, Saverio Cinieri, Rossana Berardi, Rebecca Pedersini, Amelia McCartney, Alessandro Marco Minisini, Elena Rota Caremoli, Simon Spazzapan, Emanuela Magnolfi, Antonella Brunello, Emanuela Risi, Raffaella Palumbo, Silvana Leo, Marco Colleoni, Sara Donati, Sabino De Placido, Laura Orlando, Mirco Pistelli, Veronica Parolin, Anna Mislang, Dimitri Becheri, Fabio Puglisi, Giuseppina Sanna, Elena Zafarana, Luca Boni, Giuseppe Mottino

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance

Li Li, Ling Lin, Jamunarani Veeraraghavan, Yiheng Hu, Xian Wang, Sanghoon Lee, Ying Tan, Rachel Schiff, Xiao-Song Wang

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets

Sasagu Kurozumi, Mansour Alsaleem, Cíntia J. Monteiro, Kartikeya Bhardwaj, Stacey E. P. Joosten, Takaaki Fujii, Ken Shirabe, Andrew R. Green, Ian O. Ellis, Emad A. Rakha, Nigel P. Mongan, David M. Heery, Wilbert Zwart, Steffi Oesterreich, Simon J. Johnston

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

HER2 expression on tumor-derived extracellular vesicles and circulating tumor cells in metastatic breast cancer

Afroditi Nanou, Leonie Laura Zeune, Francois-Clement Bidard, Jean-Yves Pierga, Leonardus Wendelinus Mathias Marie Terstappen

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer

Neil Portman, Heloisa H. Milioli, Sarah Alexandrou, Rhiannon Coulson, Aliza Yong, Kristine J. Fernandez, Kee Ming Chia, Ensar Halilovic, Davendra Segara, Andrew Parker, Sue Haupt, Ygal Haupt, Wayne D. Tilley, Alex Swarbrick, C. Elizabeth Caldon, Elgene Lim

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Perinatal and postnatal exposures and risk of young-onset breast cancer

Mary V. Diaz-Santana, Katie M. O’Brien, Aimee A. D’Aloisio, Gloria Regalado, Dale P. Sandler, Clarice R. Weinberg

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Targeting activated PI3K/mTOR signaling overcomes acquired resistance to CDK4/6-based therapies in preclinical models of hormone receptor-positive breast cancer

Neil A. O’Brien, Martina S. J. McDermott, Dylan Conklin, Tong Luo, Raul Ayala, Suruchi Salgar, Kevin Chau, Emmanuelle DiTomaso, Naveen Babbar, Faye Su, Alex Gaither, Sara A. Hurvitz, Ronald Linnartz, Kristine Rose, Samit Hirawat, Dennis J. Slamon

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Discordance in 21-gene recurrence scores between paired breast cancer samples is inversely associated with patient age

Sarah M. Bernhardt, Pallave Dasari, Joseph Wrin, Wendy Raymond, Suzanne Edwards, David Walsh, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Clinical implications of prospective genomic profiling of metastatic breast cancer patients

Courtney T. van Geelen, Peter Savas, Zhi Ling Teo, Stephen J. Luen, Chen-Fang Weng, Yi-An Ko, Keilly S. Kuykhoven, Franco Caramia, Roberto Salgado, Prudence A. Francis, Sarah-Jane Dawson, Stephen B. Fox, Andrew Fellowes, Sherene Loi

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Immune parameters associated with survival in metaplastic breast cancer

Xue Chao, Lili Liu, Peng Sun, Xia Yang, Mei Li, Rongzhen Luo, Yuhua Huang, Jiehua He, Jingping Yun

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

MRI background parenchymal enhancement, fibroglandular tissue, and mammographic breast density in patients with invasive lobular breast cancer on adjuvant endocrine hormonal treatment: associations with survival

Roberto Lo Gullo, Isaac Daimiel, Carolina Rossi Saccarelli, Almir Bitencourt, Varadan Sevilimedu, Danny F. Martinez, Maxine S. Jochelson, Elizabeth A. Morris, Jeffrey S. Reiner, Katja Pinker

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Impact of a ketogenic diet intervention during radiotherapy on body composition: III—final results of the KETOCOMP study for breast cancer patients

Rainer J. Klement, Colin E. Champ, Ulrike Kämmerer, Petra S. Koebrunner, Kelley Krage, Gabriele Schäfer, M. Weigel, Reinhart A. Sweeney

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Hormonal determinants of mammographic density and density change

Marike Gabrielson, Shadi Azam, Elina Hardell, Madeleine Holm, Kumari A. Ubhayasekera, Mikael Eriksson, Magnus Bäcklund, Jonas Bergquist, Kamila Czene, Per Hall

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Aspirin use and risk of breast cancer in African American women

Kimberly A. Bertrand, Traci N. Bethea, Hanna Gerlovin, Patricia F. Coogan, Lauren Barber, Lynn Rosenberg, Julie R. Palmer

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

A phase 1b study evaluating the effect of elacestrant treatment on estrogen receptor availability and estradiol binding to the estrogen receptor in metastatic breast cancer lesions using 18F-FES PET/CT imaging

Agnes Jager, Elisabeth G. E. de Vries, C. Willemien Menke-van der Houven van Oordt, Patrick Neven, Clasina M. Venema, Andor W. J. M. Glaudemans, Yamei Wang, Rebecca G. Bagley, Maureen G. Conlan, Philippe Aftimos

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Plasma thymidine kinase 1 activity and outcome of ER+ HER2− metastatic breast cancer patients treated with palbociclib and endocrine therapy

Luc Cabel, Dan Rosenblum, Florence Lerebours, Etienne Brain, Delphine Loirat, Mattias Bergqvist, Paul Cottu, Anne Donnadieu, Anne Bethune, Nicolas Kiavue, Manuel Rodrigues, Jean-Yves Pierga, Marie-Laure Tanguy, François-Clément Bidard

01.12.2020 | Research article | Ausgabe 1/2020 Open Access

Independent and joint cross-sectional associations of statin and metformin use with mammographic breast density

Erica J. Lee Argov, Teofilia Acheampong, Mary Beth Terry, Carmen B. Rodriguez, Mariangela Agovino, Ying Wei, Shweta Athilat, Parisa Tehranifar

Aktuelle Ausgaben

Neu im Fachgebiet Onkologie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Onkologie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise