Ausgabe Sonderheft 2/2006
Breast cancer research: the past and the future
Inhalt (56 Artikel)
Breast cancer susceptibility after BRCA1/2: finding the genes and potential practical applications
BAJ Ponder, AM Dunning, DF Easton, PDP Pharoah
Translating breast cancer research into clinical practice — new approaches and better outcomes
SRD Johnston
Evolution of aromatase inhibitors as an endocrine treatment for breast cancer
WR Miller
BRCA1 transcriptionally regulates genes associated with the basal breast cancer phenotype
JE Quinn, CR James, JJ Gorskii, PB Mullan, DP Harkin
Regulation of recombinational repair by the familial breast cancer susceptibility protein BRCA2
SC West, F Esashi
Chromosome translocations may play a significant role in breast cancer
KL Howarth, KA Blood, JC Pole, SL Cooke, Y-L Chua, JC Beavis, B-L Ng, PAW Edwards
Aberrant activation of Notch signalling in human breast cancer
S Stylianou, GM Collu, RB Clarke, K Brennan
Novel roles for integrins in tumour angiogenesis
M Germain, R Silva, L Reynolds, S Robinson, M DiPersio, J Kreidberg, E Georges-Labouesse, K Hodivala-Dilke
Genome-wide RNAi to identify genes that confer synthetic lethality with BRCA1
MIR Petalcorin, JS Martin, SJ Boulton
Microarray studies reveal novel genes associated with endocrine resistance in breast cancer
RS Burmi, RA McClelland, D Barrow, IO Ellis, JFR Robertson, RI Nicholson, JMW Gee
Benefits of combined treatments using antiresorptive agents and cytotoxic drugs
I Holen, H Neville-Webbe, RE Coleman
Loss of C-terminal binding protein transcriptional corepressor leads to aberrant mitosis and cell death in breast cancer cells
L Bergman, J Blaydes
Phenotypic characterization of mouse mammary epithelial stem and progenitor cells
J Stingl, CJ Eaves, CJ Watson
Characterisation of the tumour suppressor gene ZACin breast tissue
EM Valleley, SF Cordery, M Shires, V Speirs, DT Bonthron
Role of BRCT motif containing proteins in Chk1 activation
RG Beniston, CGW Smythe
hCLK2 couples FANCD2 to stalled replication forks and functions in the mammalian S-phase checkpoint
SJ Collis, LJ Barber, JS Martin, JD Ward, SJ Boulton
Poly(ADPribosyl)ation of CTCF: role in breast tumourigenesis
F Docquier, D Farrar, I Chernukhin, E Klenova
Investigating the role of Wnt signalling in lobuloalveolar development of the mammary gland
RJ Evans, C Dale
Characterization of peptide aptamers to the Anterior Gradient 2: a novel inhibitor of the tumour suppressor protein p53
A Fourtouna, E Murray, L Hayward, L Pohler, T Hupp
Role of CASP8 D302H and other apoptosis gene variants in breast cancer
SH Mistry, S Rafii, AL Shippen, G MacPherson, S Balasubramanian, MW Reed, A Cox
Functional analysis of the breast cancer associated transcriptional repressor PLU-1/JARID1B
J Taylor-Papadimitriou, A Barrett, S Santangelo, S Catchpole, J Coleman, D Hall, J Burchell, AG Scibetta
Functional analysis of normal and DCIS modified breast myoepithelial cells
M Allen, K Mulligan, S Clark, I Hart, JF Marshall, JL Jones
AGR2, a novel metastasis inducing protein with an effect on breast cancer patient survival
DL Barraclough, H Innes, S Taylor, MPA Davies, A Platt-Higgins, DR Sibson, PS Rudland, R Barraclough
Insulin-like growth factor signalling in oestrogen nonresponsive breast cancer cells
GE de Blaquiere, FEB May, BR Westley
Role of the Brk tyrosine kinase in breast cancer progression
AJ Harvey, W Court, G Box, SA Eccles, MR Crompton
The emerging role of CD44 in regulating skeletal metastasis
A Hill, S McFarlane, PG Johnston, DJJ Waugh
Evaluation of migration-stimulating factor expression for breast cancer diagnosis and prognosis
SJ Jones, IR Ellis, K Kankova, AM Thompson, P Preece, S Kazmi, SL Schor, AM Schor
Functional analysis of altered Tenascin isoform expression in breast cancer
RA Alcock, JH Pringle, JA Shaw, DL Holliday, M Allen, RA Walker, JL Jones
Role of the metastasis suppressor tetraspanin CD82/KAI 1 in regulation of signalling in breast cancer cells
E Odintsova, F Berditchevski
Expression of adrenomedullin in long-term oestrogen-deprived human breast cancer cells
A Sadler, P Darbre
Role of protein kinase B in breast cancer
EM Sale, CP Hodgkinson, NP Jones, GJ Sale
Progress towards unlocking the secrets of oestrogen receptor beta in breast cancer
V Speirs, MD Parker, AR Green, IO Ellis, AM Hanby, PTK Saunders, AM Shaaban
New molecular tools and optical technologies to dissect CXCR4 function in breast cancer
PW Thavasu, F Festy, R Springall, K Ryder, R Waters, M Kelleher, S Pinder, C Gillett, T Ng
Regulation of cytochrome P450s in breast cancer and their role for tumour growth and anticancer chemotherapy
T Friedberg, E Polson, S Weidlich
High-grade ER-negative tumour breast cancers are characteristic of both very young onset cases and patients with hereditary breast cancer
D Eccles, S Gerty, P Simmonds
Association of gene variants in the transforming growth factor beta signalling pathways with invasive breast cancer risk
S Scollen, AM Dunning, R Hesketh, JC Metcalfe
Effect of intermittent versus chronic energy restriction on breast cancer risk biomarkers in premenopausal women: a randomised pilot trial
M Harvie, M Chapman, J Cuzick, A Flyvbjerg, P Hopwood, S Jebb, G Parfitt, A Howell
Breast cancer in relation to childhood parental divorce and early adult psychiatric disorder in a British birth cohort
AU Lokugamage, M Hotopf, R Hardy, G Mishra, S Butterworth, MEJ Wadsworth, D Kuh
Increased regulatory T-cell numbers distinguish high-risk breast cancer patients and those at risk of late relapse
GJ Bates, SB Fox, C Han, RD Leek, JF Garcia, AL Harris, AH Banham
Development of anti-MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer
C Da Pieve, JN Iley, A Perkins, S Missailidis
Global histone modifications in breast cancer and their prognostic significance
AR Green, S El-Shiekh, EA Rakha, EC Paish, DM Heery, IO Ellis
The Cambridge breast intensity modulated radiotherapy trial
CE Coles, JS Wilkinson, AM Moody, ACF Hoole, N Twyman, NG Burnet
Why do most c-erbB-2/HER-2-positive breast cancer patients fail to respond to Herceptin?
ML Murphy, SKW Chan, L Bazley, NVL Hayes, WJ Gullick
Synergistic effects of cytotoxic drugs and antiresorptive agents in vitro and in vivo
PD Ottewell, M Jones, RE Coleman, I Holen
Development of small-molecule transforming growth factor beta antagonists
DJ Warner, RB Sessions, D Dawbarn, SS Prime, SJ Allen, IC Paterson
Development of breast cancer immunotherapy using MUC1 retargeted T lymphocytes
S Wilkie, MK Brenner, J Taylor-Papadimitriou, J Burchell, J Maher
Effects of combined treatment with Zometa and Taxol on endothelial cells in vitro
M Michailidou, N Brown, RE Coleman, I Holen
Breast cancer follow-up: a focus group and interview study
CA Hughes, J Connolley
'I haven't had breast cancer but I've had a mastectomy anyway': do women with ductal carcinoma in situhave appearance concerns?
F Kennedy, D Harcourt, N Rumsey
Setting a lower risk threshold for surveillance within breast cancer family services
R Black, A Fordyce, M Reis, D Goudie, L McLeish, H Carnaghan, E Anderson, J Campbell, H Gregor, E Smyth, R Davidson, M Steel
Role of macrophages in breast cancer angiogenesis in vivo
NJ Brown, L Bingle, MWR Reed, CE Lewis
Is transforming growth factor beta signalling required for breast cancer metastatic cell motility?
S Giampieri, E Sahai