Ausgabe 3/2012
Inhalt (38 Artikel)
Estrogen-related receptor alpha: an orphan finds a family
Aleksandra M Ochnik, Douglas Yee
Die and let live: harnessing BikDD to combat breast cancer stem cells
Mario Giuliano, Meghana V Trivedi, Rachel Schiff
Prognostic and predictive value of TP53mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy: results from the BIG 02-98 phase III trial
Lynnette Fernández-Cuesta, Catherine Oakman, Priscila Falagan-Lotsch, Ke-seay Smoth, Emmanuel Quinaux, Marc Buyse, M Stella Dolci, Evandro De Azambuja, Pierre Hainaut, Patrizia Dell'Orto, Denis Larsimont, Prudence A Francis, John Crown, Martine Piccart-Gebhart, Giuseppe Viale, Angelo Di Leo, Magali Olivier
Biomarkers characterization of circulating tumour cells in breast cancer patients
Rosa Nadal, Ana Fernandez, Pedro Sanchez-Rovira, Marta Salido, María Rodríguez, José Luis García-Puche, Marta Macià, Josep Maria Corominas, Miguel Delgado-Rodriguez, Lucas Gonzalez, Joan Albanell, Mónica Fernández, Francesc Solé, José Antonio Lorente, María José Serrano
Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer
Luigi Strizzi, Katharine M Hardy, Naira V Margaryan, David W Hillman, Elisabeth A Seftor, Beiyun Chen, Xochiquetzal J Geiger, E Aubrey Thompson, Wilma L Lingle, Cathy A Andorfer, Edith A Perez, Mary JC Hendrix
Back to the embryonic stage: Nodal as a biomarker for breast cancer progression
Menashe Bar-Eli
Targeting breast cancer vaccines to dendritic cells: improved immunological responses with less protein?
Anne C Armstrong, David E Gilham
Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer
Xiao Wu, Zhengmao Zhu, Weidong Li, Xiaoying Fu, Dan Su, Liya Fu, Zhiqian Zhang, Ang Luo, Xiaodong Sun, Li Fu, Jin-Tang Dong
Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study
Rebecca Ritte, Annekatrin Lukanova, Franco Berrino, Laure Dossus, Anne Tjønneland, Anja Olsen, Thure Filskov Overvad, Kim Overvad, Françoise Clavel-Chapelon, Agnès Fournier, Guy Fagherazzi, Sabine Rohrmann, Birgit Teucher, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sabina Sieri, Salvatore Panico, Rosario Tumino, Paolo Vineis, José Ramón Quirós, Genevieve Buckland, Maria-José Sánchez, Pilar Amiano, María-Dolores Chirlaque, Eva Ardanaz, Malin Sund, Per Lenner, Bas Bueno-de-Mesquita, Carla H van Gils, Petra HM Peeters, Sanda Krum-Hansen, Inger Torhild Gram, Eiliv Lund, Kay-Tee Khaw, Nick Wareham, Naomi E Allen, Timothy J Key, Isabelle Romieu, Sabina Rinaldi, Afshan Siddiq, David Cox, Elio Riboli, Rudolf Kaaks
Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
Martin A Rivas, Leandro Venturutti, Yi-Wen Huang, Roxana Schillaci, Tim Hui-Ming Huang, Patricia V Elizalde
Vitamin D and the mammary gland: a review on its role in normal development and breast cancer
Nair Lopes, Joana Paredes, José Luis Costa, Bauke Ylstra, Fernando Schmitt
Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer
Marion T Weigel, Zara Ghazoui, Anita Dunbier, Sunil Pancholi, Mitch Dowsett, Lesley-Ann Martin
Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat
Chandra R Tate, Lyndsay V Rhodes, H Chris Segar, Jennifer L Driver, F Nell Pounder, Matthew E Burow, Bridgette M Collins-Burow
Bone marrow-derived, alternatively activated macrophages enhance solid tumor growth and lung metastasis of mammary carcinoma cells in a Balb/C mouse orthotopic model
Han Jin Cho, Jae In Jung, Do Young Lim, Gyoo Taik Kwon, Song Her, Jong Hoon Park, Jung Han Yoon Park
Implications of constructed biologic subtype and its relationship to locoregional recurrence following mastectomy
Laura S Dominici, Elizabeth A Mittendorf, Xumei Wang, Jun Liu, Henry M Kuerer, Kelly K Hunt, Abenaa Brewster, Gildy V Babiera, Thomas A Buchholz, Funda Meric-Bernstam, Isabelle Bedrosian
Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy
Abigail S Caudle, Tse-Kuan Yu, Susan L Tucker, Isabelle Bedrosian, Jennifer K Litton, Ana M Gonzalez-Angulo, Karen Hoffman, Funda Meric-Bernstam, Kelly K Hunt, Thomas A Buchholz, Elizabeth A Mittendorf
Comprehensive splicing functional analysis of DNA variants of the BRCA2 gene by hybrid minigenes
Alberto Acedo, David J Sanz, Mercedes Durán, Mar Infante, Lucía Pérez-Cabornero, Cristina Miner, Eladio A Velasco
CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity
Nicola Montgomery, Ashleigh Hill, Suzanne McFarlane, Jessica Neisen, Anthony O'Grady, Susie Conlon, Karin Jirstrom, Elaine W Kay, David JJ Waugh
MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis
Chang Hui, Fu Yujie, Yuan Lijia, Yi Long, Xu Hongxia, Zhou Yong, Zhu Jundong, Zhang Qianyong, Mi Mantian
Targeted therapies in breast cancer: are heart and vessels also being targeted?
Carmen Criscitiello, Otto Metzger-Filho, Kamal S Saini, Gilberto de Castro Jr, Marie Diaz, André La Gerche, Evandro de Azambuja, Martine J Piccart-Gebhart
To bind or not to bind - FoxA1 determines estrogen receptor action in breast cancer progression
Rebecca J Watters, Panayiotis V Benos, Steffi Oesterreich
Prognostic signatures in breast cancer: correlation does not imply causation
Charlotte Ng, Britta Weigelt, Anita Grigoriadis, Jorge S Reis-Filho
Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo
Ingunn Holen, Jacob Whitworth, Faith Nutter, Alyson Evans, Hannah K Brown, Diane V Lefley, Ivana Barbaric, Mark Jones, Penelope D Ottewell
JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer
Yi Fang Lee, Lance David Miller, Xiu Bin Chan, Michael A Black, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Edison T Liu, Kartiki V Desai
Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer
Vikram K Jain, Nicholas C Turner
Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer
Susan L McGovern, Yuan Qi, Lajos Pusztai, William F Symmans, Thomas A Buchholz
Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling
Baek Gil Kim, Ming-Qing Gao, Yoon Pyo Choi, Suki Kang, Haeng Ran Park, Kyu Sub Kang, Nam Hoon Cho
Crk adaptor proteins act as key signaling integrators for breast tumorigenesis
Kelly E Fathers, Emily S Bell, Charles V Rajadurai, Sean Cory, Hong Zhao, Anna Mourskaia, Dongmei Zuo, Jason Madore, Anie Monast, Anne-Marie Mes-Masson, Andree-Anne Grosset, Louis Gaboury, Michael Hallet, Peter Siegel, Morag Park
Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases
Johanna E Lotsari, Annette Gylling, Wael M Abdel-Rahman, Taina T Nieminen, Kristiina Aittomäki, Marjukka Friman, Reino Pitkänen, Markku Aarnio, Heikki J Järvinen, Jukka-Pekka Mecklin, Teijo Kuopio, Päivi Peltomäki
γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells
Céline Séveno, Delphine Loussouarn, Sophie Bréchet, Mario Campone, Philippe Juin, Sophie Barillé-Nion
Dual-energy contrast-enhanced digital mammography: initial clinical results of a multireader, multicase study
Clarisse Dromain, Fabienne Thibault, Felix Diekmann, Eva M Fallenberg, Roberta A Jong, Marcia Koomen, R Edward Hendrick, Anne Tardivon, Alicia Toledano
Endometrial cancer survival after breast cancer in relation to tamoxifen treatment: Pooled results from three countries
Michael E Jones, Flora E van Leeuwen, Wilhelmina E Hoogendoorn, Marian JE Mourits, Harry Hollema, Hester van Boven, Michael F Press, Leslie Bernstein, Anthony J Swerdlow
Determining sensitivity and specificity of HER2 testing in breast cancer using a tissue micro-array approach
Tim JA Dekker, Susan Ter Borg, Gerrit KJ Hooijer, Sybren Lf Meijer, Jelle Wesseling, James E Boers, Ed Schuuring, Jos Bart, Joost van Gorp, Wilma E Mesker, Judith R Kroep, Vincent THBM Smit, Marc J van de Vijver
17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration
Juliette A Aka, Mouna Zerradi, François Houle, Jacques Huot, Sheng-Xiang Lin
Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression
Todd P Knutson, Andrea R Daniel, Danhua Fan, Kevin AT Silverstein, Kyle R Covington, Suzanne AW Fuqua, Carol A Lange
Paracrine interactions between primary human macrophages and human fibroblasts enhance murine mammary gland humanization in vivo
Jodie M Fleming, Tyler C Miller, Michal Kidacki, Erika Ginsburg, Christina H Stuelten, Delisha A Stewart, Melissa A Troester, Barbara K Vonderhaar
Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells
Xiu-Rong Ren, Junping Wei, Gangjun Lei, Jiangbo Wang, Jiuyi Lu, Wenle Xia, Neil Spector, Larry S Barak, Timothy M Clay, Takuya Osada, Erika Hamilton, Kimberly Blackwell, Amy C Hobeika, Michael A Morse, H Kim Lyerly, Wei Chen