Ausgabe 5/2013
Inhalt (41 Artikel)
Metabolic interaction between cancer cells and stromal cells according to breast cancer molecular subtype
Junjeong Choi, Do Hee Kim, Woo Hee Jung, Ja Seung Koo
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
Suzanne A Eccles, Eric O Aboagye, Simak Ali, Annie S Anderson, Jo Armes, Fedor Berditchevski, Jeremy P Blaydes, Keith Brennan, Nicola J Brown, Helen E Bryant, Nigel J Bundred, Joy M Burchell, Anna M Campbell, Jason S Carroll, Robert B Clarke, Charlotte E Coles, Gary JR Cook, Angela Cox, Nicola J Curtin, Lodewijk V Dekker, Isabel dos Santos Silva, Stephen W Duffy, Douglas F Easton, Diana M Eccles, Dylan R Edwards, Joanne Edwards, D Gareth Evans, Deborah F Fenlon, James M Flanagan, Claire Foster, William M Gallagher, Montserrat Garcia-Closas, Julia M W Gee, Andy J Gescher, Vicky Goh, Ashley M Groves, Amanda J Harvey, Michelle Harvie, Bryan T Hennessy, Stephen Hiscox, Ingunn Holen, Sacha J Howell, Anthony Howell, Gill Hubbard, Nick Hulbert-Williams, Myra S Hunter, Bharat Jasani, Louise J Jones, Timothy J Key, Cliona C Kirwan, Anthony Kong, Ian H Kunkler, Simon P Langdon, Martin O Leach, David J Mann, John F Marshall, Lesley Ann Martin, Stewart G Martin, Jennifer E Macdougall, David W Miles, William R Miller, Joanna R Morris, Sue M Moss, Paul Mullan, Rachel Natrajan, James PB O’Connor, Rosemary O’Connor, Carlo Palmieri, Paul D P Pharoah, Emad A Rakha, Elizabeth Reed, Simon P Robinson, Erik Sahai, John M Saxton, Peter Schmid, Matthew J Smalley, Valerie Speirs, Robert Stein, John Stingl, Charles H Streuli, Andrew N J Tutt, Galina Velikova, Rosemary A Walker, Christine J Watson, Kaye J Williams, Leonie S Young, Alastair M Thompson
AutoDensity: an automated method to measure mammographic breast density that predicts breast cancer risk and screening outcomes
Carolyn Nickson, Yulia Arzhaeva, Zoe Aitken, Tarek Elgindy, Mitchell Buckley, Min Li, Dallas R English, Anne M Kavanagh
Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition
Rebecca A Whipple, Michele I Vitolo, Amanda E Boggs, Monica S Charpentier, Keyata Thompson, Stuart S Martin
A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients
Suyoun Chung, Siew-Kee Low, Hitoshi Zembutsu, Atsushi Takahashi, Michiaki Kubo, Mitsunori Sasa, Yusuke Nakamura
Breast cancer receptor status and stage at diagnosis in over 1,200 consecutive public hospital patients in Soweto, South Africa: a case series
Valerie A McCormack, Maureen Joffe, Eunice van den Berg, Nadine Broeze, Isabel dos Santos Silva, Isabelle Romieu, Judith S Jacobson, Alfred I Neugut, Joachim Schüz, Herbert Cubasch
Association between mammographic density and basal-like and luminal A breast cancer subtypes
Hilda Razzaghi, Melissa A Troester, Gretchen L Gierach, Andrew F Olshan, Bonnie C Yankaskas, Robert C Millikan
Quantitative measures of estrogen receptor expression in relation to breast cancer-specific mortality risk among white women and black women
Huiyan Ma, Yani Lu, Polly A Marchbanks, Suzanne G Folger, Brian L Strom, Jill A McDonald, Michael S Simon, Linda K Weiss, Kathleen E Malone, Ronald T Burkman, Jane Sullivan-Halley, Dennis M Deapen, Michael F Press, Leslie Bernstein
Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development
Christiane Danilo, Jorge L Gutierrez-Pajares, Maria Antonietta Mainieri, Isabelle Mercier, Michael P Lisanti, Philippe G Frank
Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
Rebecca A Dent, Geoffrey J Lindeman, Mark Clemons, Hans Wildiers, Arlene Chan, Nicole J McCarthy, Christian F Singer, Elizabeth S Lowe, Claire L Watkins, James Carmichael
Assessing tumor contrast in radiographically dense breast tissue using Diffuse Optical Spectroscopic Imaging (DOSI)
Anaïs Leproux, Amanda Durkin, Montana Compton, Albert E Cerussi, Enrico Gratton, Bruce J Tromberg
The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer: a retrospective study including patients from the randomised Stockholm tamoxifen trials
Elin Karlsson, Gizeh Pérez-Tenorio, Risul Amin, Josefine Bostner, Lambert Skoog, Tommy Fornander, Dennis C Sgroi, Bo Nordenskjöld, Anna-Lotta Hallbeck, Olle Stål
Informed choice about breast cancer prevention: randomized controlled trial of an online decision aid intervention
Ida J Korfage, Andrea Fuhrel-Forbis, Peter A Ubel, Brian J Zikmund-Fisher, Sarah M Greene, Jennifer B McClure, Dylan M Smith, Sharon Hensley Alford, Angela Fagerlin
Impact of breast cancer subtypes on 3-year survival among adolescent and young adult women
Theresa H M Keegan, David J Press, Li Tao, Mindy C DeRouen, Allison W Kurian, Christina A Clarke, Scarlett L Gomez
Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
D Joseph Jerry, Grace Makari-Judson, Giovanna M Crisi, Karen A Dunphy
Misuse of blood serum to assess exposure to bisphenol A and phthalates
Antonia M Calafat, Holger M Koch, Shanna H Swan, Russ Hauser, Lynn R Goldman, Bruce P Lanphear, Matthew P Longnecker, Ruthann A Rudel, Susan L Teitelbaum, Robin M Whyatt, Mary S Wolff
Priming BCL-2 to kill: the combination therapy of tamoxifen and ABT-199 in ER+ breast cancer
Jing Deng, Anthony Letai
Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency
Rachel L Atkinson, Wei T Yang, Daniel G Rosen, Melissa D Landis, Helen Wong, Michael T Lewis, Chad J Creighton, Krystal R Sexton, Sue G Hilsenbeck, Aysegul A Sahin, Abenaa M Brewster, Wendy A Woodward, Jenny C Chang
Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment
Ning Yang, Chengbao Liu, Amy R Peck, Melanie A Girondo, Alicia F Yanac, Thai H Tran, Fransiscus E Utama, Takemi Tanaka, Boris Freydin, Inna Chervoneva, Terry Hyslop, Albert J Kovatich, Jeffrey A Hooke, Craig D Shriver, Hallgeir Rui
Mammary Carcinoma Cell Derived Cyclooxygenase 2 Suppresses Tumor Immune Surveillanceby Enhancing Intratumoral Immune Checkpoint Activity
Nune Markosyan, Edward P Chen, Rebecca A Evans, Victoire Ndong, Robert H Vonderheide, Emer M Smyth
A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model
Keunhee Oh, Ok-Young Lee, Suh Youn Shon, Onyou Nam, Po Mee Ryu, Myung Won Seo, Dong-Sup Lee
Role of HGF in epithelial–stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ
Patricia Casbas-Hernandez, Monica D’Arcy, Erick Roman-Perez, Heather Ann Brauer, Kirk McNaughton, Samantha M Miller, Raghav K Chhetri, Amy L Oldenburg, Jodie M Fleming, Keith D Amos, Liza Makowski, Melissa A Troester
An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models
Wenle Xia, Emanual F Petricoin III, Sumin Zhao, Leihua Liu, Takuya Osada, Qing Cheng, Julia D Wulfkuhle, William R Gwin, Xiaoyi Yang, Rosa I Gallagher, Sarah Bacus, H Kim Lyerly, Neil L Spector
Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers
Giampaolo Bianchini, Lajos Pusztai, Thomas Karn, Takayuki Iwamoto, Achim Rody, Catherine M Kelly, Volkmar Müller, Marcus Schmidt, Yuan Qi, Uwe Holtrich, Sven Becker, Libero Santarpia, Angelica Fasolo, Gianluca Del Conte, Milvia Zambetti, Christos Sotiriou, Benjamin Haibe-Kains, W Fraser Symmans, Luca Gianni
Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration
Kristi Bray, Melissa Gillette, Jeanette Young, Elizabeth Loughran, Melissa Hwang, James Cooper Sears, Tracy Vargo-Gogola
Association of CYP2D6metabolizer status with mammographic density change in response to tamoxifen treatment
Jingmei Li, Kamila Czene, Hiltrud Brauch, Werner Schroth, Pilar Saladores, Yi Li, Keith Humphreys, Per Hall
The presence and prognostic impact of apoptotic and nonapoptotic disseminated tumor cells in the bone marrow of primary breast cancer patients after neoadjuvant chemotherapy
Andreas Daniel Hartkopf, Florin-Andrei Taran, Markus Wallwiener, Carsten Hagenbeck, Carola Melcher, Natalia Krawczyk, Markus Hahn, Diethelm Wallwiener, Tanja Fehm
‘The charmingest place’: non-coding RNA, lineage tracing, tumor heterogeneity, metastasis and metabolism - new methods in mammary gland development and cancer: the fifth ENBDC Workshop
Robert B Clarke, John Stingl, Maria Vivanco, Mohamed Bentires-Alj
Clinical application of high-throughput genomic technologies for treatment selection in breast cancer
Aaron R Hansen, Philippe L Bedard
Pattern of recurrence of early breast cancer is different according to intrinsic subtype and proliferation index
Nuria Ribelles, Lidia Perez-Villa, Jose Manuel Jerez, Bella Pajares, Luis Vicioso, Begoña Jimenez, Vanessa de Luque, Leonardo Franco, Elena Gallego, Antonia Marquez, Martina Alvarez, Alfonso Sanchez-Muñoz, Luis Perez-Rivas, Emilio Alba
Pre-diagnosis oophorectomy, estrogen therapy and mortality in a cohort of women diagnosed with breast cancer
Hazel B Nichols, Amy Trentham-Dietz, Polly A Newcomb, Kathleen M Egan, Linda J Titus, John M Hampton, Kala Visvanathan
Pubertal high fat diet: effects on mammary cancer development
Yong Zhao, Ying Siow Tan, Mark D Aupperlee, Ingeborg M Langohr, Erin L Kirk, Melissa A Troester, Richard C Schwartz, Sandra Z Haslam
Par-4 prevents breast cancer recurrence
Nikhil Hebbar, Tripti Shrestha-Bhattarai, Vivek M Rangnekar
Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer
Shuiliang Wang, Jingcao Huang, Hui Lyu, Bo Cai, Xiaoping Yang, Fang Li, Jianming Tan, Susan M Edgerton, Ann D Thor, Choon-Kee Lee, Bolin Liu
AXL/epidermal growth factor receptor (EGFR) complexes in breast cancer - culprits for resistance to EGFR inhibitors?
Marinus R Heideman, Nancy E Hynes
An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk
Christina Yau, John Sninsky, Shirley Kwok, Alice Wang, Amy Degnim, James N Ingle, Cheryl Gillett, Andrew Tutt, Fred Waldman, Dan Moore, Laura Esserman, Christopher C Benz
Obesity associated alterations in the biology of adipose stem cells mediate enhanced tumorigenesis by estrogen dependent pathways
Amy L Strong, Thomas A Strong, Lyndsay V Rhodes, Julie A Semon, Xiujuan Zhang, Zhenzhen Shi, Shijia Zhang, Jeffrey M Gimble, Matthew E Burow, Bruce A Bunnell
Top Notch cancer stem cells by paracrine NF-κB signaling in breast cancer
Weizhou Zhang, Sergei I Grivennikov