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Breast Cancer Research and Treatment

Ausgabe 1/2010

Inhalt (32 Artikel)

Review

Approaches and limitations of phosphatidylinositol-3-kinase pathway activation status as a predictive biomarker in the clinical development of targeted therapy

Christina M. Coughlin, Daniel S. Johnston, Andrew Strahs, Michael E. Burczynski, Sarah Bacus, Jason Hill, Jay M. Feingold, Charles Zacharchuk, Anna Berkenblit

Review

Fertility drugs and the risk of breast cancer: a meta-analysis and review

Tony G. Zreik, Ali Mazloom, Yanli Chen, Marina Vannucci, Chelsea C. Pinnix, Stephanie Fulton, Mersiha Hadziahmetovic, Nadia Asmar, Adnan R. Munkarah, Chakib M. Ayoub, Ferial Shihadeh, Ghina Berjawi, Antoine Hannoun, Pierre Zalloua, Christine Wogan, Bouthaina Dabaja

Preclinical study

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

Alexandra Hockla, Derek C. Radisky, Evette S. Radisky

Preclinical study

UHRF1 inhibits MDR1 gene transcription and sensitizes breast cancer cells to anticancer drugs

Wei Jin, Yang Liu, Si-guang Xu, Wen-jin Yin, Jun-jie Li, Jin-ming Yang, Zhi-ming Shao

Preclinical study

The G12 family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion

Eun-Sook Kim, Jae-Boon Jeong, Seonhoe Kim, Kyung-Min Lee, Eunyoung Ko, Dong-Young Noh, Ki-Tae Hwang, Ji Hee Ha, Chang Ho Lee, Sang Geon Kim, Aree Moon

Preclinical study

17β-Estradiol enhances α5 integrin subunit gene expression through ERα–Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells

Diego Sisci, Emilia Middea, Catia Morelli, Marilena Lanzino, Saveria Aquila, Pietro Rizza, Stefania Catalano, Ivan Casaburi, Marcello Maggiolini, Sebastiano Andò

Preclinical study

Synergistic activity of letrozole and sorafenib on breast cancer cells

Mara A. Bonelli, Claudia Fumarola, Roberta R. Alfieri, Silvia La Monica, Andrea Cavazzoni, Maricla Galetti, Rita Gatti, Silvana Belletti, Adrian L. Harris, Stephen B. Fox, Dean B. Evans, Mitch Dowsett, Lesley-Ann Martin, Alberto Bottini, Daniele Generali, Pier Giorgio Petronini

Preclinical study

The role of microRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells

Selma Masri, Zheng Liu, Sheryl Phung, Emily Wang, Yate-Ching Yuan, Shiuan Chen

Preclinical study

New troglitazone derivatives devoid of PPARγ agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines

Christelle Colin, Stéphane Salamone, Isabelle Grillier-Vuissoz, Michel Boisbrun, Sandra Kuntz, Julie Lecomte, Yves Chapleur, Stéphane Flament

Preclinical study

Beyond bisphosphonates: photodynamic therapy structurally augments metastatically involved vertebrae and destroys tumor tissue

Emily Won, Lisa Wise-Milestone, Margarete K. Akens, Shane Burch, Albert J. M. Yee, Brian C. Wilson, Cari M. Whyne

Preclinical study

Anti-HER2 immunoliposomes for selective delivery of electron paramagnetic resonance imaging probes to HER2-overexpressing breast tumor cells

Scott R. Burks, Luciana F. Macedo, Eugene D. Barth, Katherine H. Tkaczuk, Stuart S. Martin, Gerald M. Rosen, Howard J. Halpern, Angela M. Brodie, Joseph P. Y. Kao

Clinical trial

Effect of neoadjuvant anthracycline–taxane-based chemotherapy in different biological breast cancer phenotypes: overall results from the GeparTrio study

Jens Huober, Gunter von Minckwitz, Carsten Denkert, Hans Tesch, Erich Weiss, Dirk Michael Zahm, Antje Belau, Fariba Khandan, Maik Hauschild, Christoph Thomssen, Bernhard Högel, Silvia Darb-Esfahani, Keyur Mehta, Sibylle Loibl

Clinical trial

Intraoperative radiotherapy during breast conserving surgery: a study on 1,822 cases treated with electrons

Umberto Veronesi, Roberto Orecchia, Alberto Luini, Viviana Galimberti, Stefano Zurrida, Mattia Intra, Paolo Veronesi, Paolo Arnone, Maria Cristina Leonardi, Mario Ciocca, Roberta Lazzari, Pietro Caldarella, Nicole Rotmensz, Claudia Sangalli, Daniele Sances, Patrick Maisonneuve

Clinical trial

Reversal of skeletal effects of endocrine treatments in the Intergroup Exemestane Study

Robert E. Coleman, Linda M. Banks, Samia I. Girgis, Eduard Vrdoljak, John Fox, Simon J. Cawthorn, Ashraf Patel, Judith M. Bliss, R. Charles Coombes, Lucy S. Kilburn

Clinical trial

Multimodal exercise improves quality of life of women being treated for breast cancer, but at what cost? Randomized trial with economic evaluation

Terry P. Haines, Patricia Sinnamon, Neil G. Wetzig, Margot Lehman, Euan Walpole, Tony Pratt, Amanda Smith

Clinical trial

The association between biological subtype and locoregional recurrence in newly diagnosed breast cancer

Zsolt Gabos, John Thoms, Sunita Ghosh, John Hanson, Jean Deschênes, Siham Sabri, Bassam Abdulkarim

Epidemiology

Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers

Susan M. Domchek, Tara M. Friebel, Judy E. Garber, Claudine Isaacs, Ellen Matloff, Rosalind Eeles, D. Gareth Evans, Wendy Rubinstein, Christian F. Singer, Stephen Rubin, Henry T. Lynch, Mary B. Daly, Jeffrey Weitzel, Patricia A. Ganz, Gabriella Pichert, Olufunmilayo I. Olopade, Gail Tomlinson, Nadine Tung, Joanne L. Blum, Fergus Couch, Timothy R. Rebbeck

Epidemiology

Weight gain is associated with increased risk of hot flashes in breast cancer survivors on aromatase inhibitors

H. Irene Su, Mary D. Sammel, Erin Springer, Ellen W. Freeman, Angela DeMichele, Jun J. Mao

Epidemiology

Are there racial/ethnic disparities among women younger than 40 undergoing mammography?

Julie M. Kapp, Rod Walker, Sebastien Haneuse, Diana S. M. Buist, Bonnie C. Yankaskas

Epidemiology

XPD Lys751Gln polymorphism and breast cancer susceptibility: a meta-analysis involving 28,709 subjects

Li-Xin Qiu, Lei Yao, Jian Zhang, Xiao-Dong Zhu, Xin-Min Zhao, Kai Xue, Chen Mao, Bo Chen, Ping Zhan, Hui Yuan, Xi-Chun Hu

Epidemiology

Genetic variants in trinucleotide repeat-containing 9 (TNRC9) are associated with risk of estrogen receptor positive breast cancer in a Chinese population

Jie Liang, Peizhan Chen, Zhibin Hu, Hao Shen, Furu Wang, Lu Chen, Mian Li, Jinhai Tang, Hui Wang, Hongbing Shen

Brief Report

Four new cases of double heterozygosity for BRCA1 and BRCA2 gene mutations: clinical, pathological, and family characteristics

Monica Zuradelli, Bernard Peissel, Siranoush Manoukian, Daniela Zaffaroni, Monica Barile, Valeria Pensotti, Ugo Cavallari, Giovanna Masci, Frederique Mariette, Anne Caroline Benski, Armando Santoro, Paolo Radice

Brief Report

TMS, a chemically modified herbal derivative of Resveratrol, induces cell death by targeting Bax

Sarah E. Aiyar, Hoyong Park, Paulomi B. Aldo, Gil Mor, John J. Gildea, Aaron L. Miller, E. Brad Thompson, J. David Castle, Sanghee Kim, Richard J. Santen

Brief Report

Angiosarcoma following MammoSite® partial breast irradiation

Samuel Andrews, Rebecca Wilcoxon, Jo Benda, Geraldine Jacobson

Brief Report

Mutation and association analysis of GEN1 in breast cancer susceptibility

Clare Turnbull, Sarah Hines, Anthony Renwick, Deborah Hughes, David Pernet, Anna Elliott, Sheila Seal, Margaret Warren-Perry, D. Gareth Evans, Diana Eccles, Michael R. Stratton, Nazneen Rahman

Letter to the Editor

Combined UGT1A1 and UGT1A6 genotypes together with a stressful life event increase breast cancer risk

Christina Justenhoven, Stefan Winter, Thomas Dünnebier, Ute Hamann, Christian Baisch, Sylvia Rabstein, Anne Spickenheuer, Volker Harth, Beate Pesch, Thomas Brüning, Yon-Dschun Ko, Hiltrud Brauch

Update Onkologie

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