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Breast Cancer Research and Treatment

Ausgabe 2/2010

Inhalt (28 Artikel)

Preclinical Study

A novel doxorubicin-mitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy in multidrug resistant human breast cancer cells

Adam J. Shuhendler, Richard Y. Cheung, Janet Manias, Allegra Connor, Andrew M. Rauth, Xiao Yu Wu

Preclinical Study

Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells

Elif Damla Arisan, Ozgur Kutuk, Tugsan Tezil, Cagri Bodur, Dilek Telci, Huveyda Basaga

Preclinical Study

Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen

Hany Onsy Habashy, Desmond G. Powe, Cindy M. Staka, Emad A. Rakha, Graham Ball, Andrew R. Green, Mohammed Aleskandarany, E. Claire Paish, R. Douglas Macmillan, Robert I. Nicholson, Ian O. Ellis, Julia M. W. Gee

Preclinical Study

Identification and characterization of two novel germ line p53 mutations in the non-LFS/non-LFL breast cancer families in Chinese population

A-Yong Cao, Wei Jin, Peng-Cheng Shi, Gen-hong Di, Zhen-Zhou Shen, Zhi-Ming Shao

Preclinical Study

Decreased TGFβ signaling and increased COX2 expression in high risk women with increased mammographic breast density

Wei Tse Yang, Michael T. Lewis, Kenneth Hess, Helen Wong, Anna Tsimelzon, Nese Karadag, Michelina Cairo, Caimaio Wei, Funda Meric-Bernstam, Powel Brown, Banu Arun, Gabriel N. Hortobagyi, Aysegul Sahin, Jenny C. Chang

Preclinical Study

Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer

Robin L. Jones, Janine Salter, Roger A’Hern, Ash Nerurkar, Marina Parton, Jorge S. Reis-Filho, Ian E. Smith, Mitchell Dowsett

Preclinical Study

Defining the therapeutic window of vertebral photodynamic therapy in a murine pre-clinical model of breast cancer metastasis using the photosensitizer BPD-MA (Verteporfin)

Margarete K. Akens, Michael R. Hardisty, Brian C. Wilson, Joerg Schwock, Cari M. Whyne, Shane Burch, Albert J. M. Yee

Preclinical Study

Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue

Dung-Tsa Chen, Aejaz Nasir, Aedin Culhane, Chinnambally Venkataramu, William Fulp, Renee Rubio, Tao Wang, Deepak Agrawal, Susan M. McCarthy, Mike Gruidl, Gregory Bloom, Tove Anderson, Joe White, John Quackenbush, Timothy Yeatman

Clinical trial

Association of low tumor RNA integrity with response to chemotherapy in breast cancer patients

Amadeo M. Parissenti, Judy-Anne W. Chapman, Harriette J. Kahn, Baoqing Guo, Lei Han, Patti O’Brien, Mark P. Clemons, Roberta Jong, Rebecca Dent, Barbara Fitzgerald, Kathleen I. Pritchard, Lois E. Shepherd, Maureen E. Trudeau

Clinical trial

Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients

K. Hancke, D. Grubeck, N. Hauser, R. Kreienberg, J. M. Weiss

Clinical Trial

Phosphatidyl-inositol-3-kinase alpha catalytic subunit mutation and response to neoadjuvant endocrine therapy for estrogen receptor positive breast cancer

Matthew J. Ellis, Li Lin, Robert Crowder, Yu Tao, Jeremy Hoog, Jacqueline Snider, Sherri Davies, Katherine DeSchryver, Dean B. Evans, Jutta Steinseifer, Raj Bandaru, WeiHua Liu, Humphrey Gardner, Vladimir Semiglazov, Mark Watson, Kelly Hunt, John Olson, José Baselga

Clinical trial

Screening for clonal hematopoiesis as a predictive marker for development of therapy-related myeloid neoplasia (t-MN) following neoadjuvant therapy for breast cancer: a Southwest Oncology Group study (S0012)

Marilyn L. Slovak, Victoria Bedell, Danika Lew, Kathy S. Albain, Georgiana K. Ellis, Robert B. Livingston, Silvana Martino, Edith A. Perez, Gabriel N. Hortobagyi, Dorie Sher, Wendy Stock

Clinical trial

Assessment of false-negative cases of breast MR imaging in women with a familial or genetic predisposition

Inge-Marie A. Obdeijn, Claudette E. Loo, Adriana J. Rijnsburger, Martin N. J. M. Wasser, Elisabeth Bergers, Theo Kok, Jan G. M. Klijn, Carla Boetes

Clinical trial

Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2

S. M. Domchek, M. M. Gaudet, J. E. Stopfer, M. H. Fleischaut, J. Powers, N. Kauff, K. Offit, K. L. Nathanson, M. Robson

Clinical trial

The impact of preoperative breast MRI on the re-excision rate in invasive lobular carcinoma of the breast

R. M. Mann, C. E. Loo, T. Wobbes, P. Bult, J. O. Barentsz, K. G. A. Gilhuijs, C. Boetes

Epidemiology

Variation in genes required for normal mitosis and risk of breast cancer

J. E. Olson, X. Wang, E. L. Goode, V. S. Pankratz, Z. S. Fredericksen, R. A. Vierkant, P. D. P. Pharoah, J. R. Cerhan, F. J. Couch

Epidemiology

Mutations in the mitochondrial DNA D-loop region and breast cancer risk

Chuanzhong Ye, Xiao Ou Shu, Larry Pierce, Wanqing Wen, Regina Courtney, Yu-Tang Gao, Wei Zheng, Qiuyin Cai

Epidemiology

The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer

Gabrielle Colleran, Niall McInerney, Andrew Rowan, Ella Barclay, Angela M. Jones, Catherine Curran, Nicola Miller, Michael Kerin, Ian Tomlinson, Elinor Sawyer

Epidemiology

ATM germline mutations in women with familial breast cancer and a relative with haematological malignancy

Laura La Paglia, Anthony Laugé, Jérémie Weber, Jérôme Champ, Eve Cavaciuti, Antonio Russo, Jean-Louis Viovy, Dominique Stoppa-Lyonnet

Epidemiology

Association of genetic variation in mitotic kinases with breast cancer risk

Xianshu Wang, Zachary S. Fredericksen, Robert A. Vierkant, Matthew L. Kosel, V. Shane Pankratz, James R. Cerhan, Christina Justenhoven, Hiltrud Brauch, Janet E. Olson, Fergus J. Couch

Epidemiology

Green tea consumption and breast cancer risk or recurrence: a meta-analysis

Adeyemi A. Ogunleye, Fei Xue, Karin B. Michels

Report

Are mammography recommendations in women younger than 40 related to increased risk?

Julie M. Kapp, Bonnie C. Yankaskas, Michael L. LeFevre

Report

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

Jeremy M. Arnold, David Y. H. Choong, Ella R. Thompson, Nic Waddell, Geoffrey J. Lindeman, Jane E. Visvader, Ian G. Campbell, Georgia Chenevix-Trench

Letter to the editor

Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-β1 and TNF-α

Javier Guerrero, Nicolás Tobar, Mónica Cáceres, Lorena Espinoza, Paula Escobar, Javier Dotor, Patricio C. Smith, Jorge Martínez

Update Onkologie

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