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Breast Cancer Research and Treatment

Ausgabe 2/2010

Inhalt (35 Artikel)

Preclinical study

Association of rare MSH6 variants with familial breast cancer

Marijke Wasielewski, Muhammad Riaz, Joyce Vermeulen, Ans van den Ouweland, Ineke Labrijn-Marks, Renske Olmer, Linda van der Spaa, Jan G. M. Klijn, Hanne Meijers-Heijboer, Dennis Dooijes, Mieke Schutte

Preclinical study

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action

Wei Wang, Elizabeth R. Rayburn, Sadanandan E. Velu, Deng Chen, Dwayaja H. Nadkarni, Srinivasan Murugesan, Dongquan Chen, Ruiwen Zhang

Preclinical study

Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy

Kathryn N. Phoenix, Frank Vumbaca, Melissa M. Fox, Rebecca Evans, Kevin P. Claffey

Preclinical study

ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole

Martin Smollich, Martin Götte, Jeanett Fischgräbe, Luciana F. Macedo, Angela Brodie, Shiuan Chen, Isabel Radke, Ludwig Kiesel, Pia Wülfing

Preclinical study

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer

Wei Jin, Li Chen, Ying Chen, Si-guang Xu, Gen-hong Di, Wen-jin Yin, Jiong Wu, Zhi-ming Shao

Preclinical study

RACK1 promotes breast carcinoma proliferation and invasion/metastasis in vitro and in vivo

Xi-Xi Cao, Jing-Da Xu, Jia-Wen Xu, Xiao-Li Liu, Yuan-Yuan Cheng, Wen-Juan Wang, Qing-Quan Li, Qi Chen, Zu-De Xu, Xiu-Ping Liu

Preclinical study

Effects of the combined blockade of EGFR and ErbB-2 on signal transduction and regulation of cell cycle regulatory proteins in breast cancer cells

Amelia D’Alessio, Antonella De Luca, Monica R. Maiello, Luana Lamura, Anna Maria Rachiglio, Maria Napolitano, Marianna Gallo, Nicola Normanno

Preclinical study

Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ

M. Sharma, A. H. Beck, J. A. Webster, I. Espinosa, K. Montgomery, S. Varma, M. van de Rijn, K. C. Jensen, R. B. West

Preclinical study

Breast cancer cell CD200 expression regulates immune response to EMT6 tumor cells in mice

Reginald M. Gorczynski, Zhiqi Chen, Jun Diao, Ismat Khatri, Karrie Wong, Kai Yu, Julia Behnke

Clinical trial

Physical activity levels after treatment for breast cancer: one-year follow-up

Nele Devoogdt, Marijke Van Kampen, Inge Geraerts, Tina Coremans, Steffen Fieuws, Johan Lefevre, Renaat Philippaerts, Steven Truijen, Patrick Neven, Marie-Rose Christiaens

Clinical trial

Final results of a phase II study of nab-paclitaxel, bevacizumab, and gemcitabine as first-line therapy for patients with HER2-negative metastatic breast cancer

Christopher Lobo, Gilberto Lopes, Odalys Baez, Aurelio Castrellon, Annapoorna Ferrell, Connie Higgins, Erin Hurley, Judith Hurley, Isildinha Reis, Stephen Richman, Pearl Seo, Orlando Silva, Joyce Slingerland, Keleni Tukia, Catherine Welsh, Stefan Glück

Clinical trial

Monitoring serum HER2 levels during neoadjuvant trastuzumab treatment within the GeparQuattro trial

Isabell Witzel, Sibylle Loibl, Gunter von Minckwitz, Christoph Mundhenke, Jens Huober, Claus Hanusch, Stephan Henschen, Maik Hauschild, Tilmann Lantzsch, Hans Tesch, Kunibert Latos, Marianne Just, Jörn Hilfrich, Jana Barinoff, Christine zu Eulenburg, Marc Roller, Michael Untch, Volkmar Müller

Clinical trial

Corticosteroid treatment and timing of surgery in idiopathic granulomatous mastitis confusing with breast carcinoma

Fazilet Erozgen, Yeliz E. Ersoy, Murat Akaydin, Naim Memmi, Aysun Simsek Celik, Fatih Celebi, Deniz Guzey, Rafet Kaplan

Clinical trial

Results of a phase II study comparing three dosing regimens of fulvestrant in postmenopausal women with advanced breast cancer (FINDER2)

Kathleen I. Pritchard, Janusz Rolski, Zsuzsanna Papai, Louis Mauriac, Fatima Cardoso, Jose Chang, Lawrence Panasci, Carmen Ianuli, Zsuzsanna Kahan, Kenjiro Fukase, Justin P. O. Lindemann, Merran P. Macpherson, Patrick Neven

Clinical trial

Multicenter phase II randomized trial evaluating antiangiogenic therapy with sunitinib as consolidation after objective response to taxane chemotherapy in women with HER2-negative metastatic breast cancer

H. Wildiers, C. Fontaine, P. Vuylsteke, M. Martens, J. L. Canon, W. Wynendaele, C. Focan, J. De Greve, P. Squifflet, R. Paridaens

Clinical trial

A pilot study of adjuvant nanoparticle albumin-bound (nab) paclitaxel and cyclophosphamide, with trastuzumab in HER2-positive patients, in the treatment of early-stage breast cancer

Denise Yardley, Howard Burris III, Nancy Peacock, Eric Raefsky, Marianne Melnik, Roger Inhorn, Dianna Shipley, John Hainsworth

Epidemiology

Depressive symptoms among young breast cancer survivors: the importance of reproductive concerns

Jessica R. Gorman, Vanessa L. Malcarne, Scott C. Roesch, Lisa Madlensky, John P. Pierce

Epidemiology

BRCA2 N372H polymorphism and breast cancer susceptibility: a meta-analysis involving 44,903 subjects

Li-Xin Qiu, Lei Yao, Kai Xue, Jian Zhang, Chen Mao, Bo Chen, Ping Zhan, Hui Yuan, Xi-Chun Hu

Epidemiology

Adjuvant systemic therapy for breast cancer in BRCA1/BRCA2 mutation carriers in a population-based study of risk of contralateral breast cancer

Kerryn W. Reding, Jonine L. Bernstein, Bryan M. Langholz, Leslie Bernstein, Robert W. Haile, Colin B. Begg, Charles F. Lynch, Patrick Concannon, Ake Borg, Sharon N. Teraoka, Therese Törngren, Anh Diep, Shanyan Xue, Lisbeth Bertelsen, Xiaolin Liang, Anne S. Reiner, Marinela Capanu, Kathleen E. Malone

Epidemiology

Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls

Xiaowei Qi, Xiangyu Ma, Xinhua Yang, Linjun Fan, Yi Zhang, Fan Zhang, Li Chen, Yan Zhou, Jun Jiang

Epidemiology

Quality of life among women recently diagnosed with invasive breast cancer: the Pathways Study

Marilyn L. Kwan, Isaac Joshua Ergas, Carol P. Somkin, Charles P. Quesenberry Jr., Alfred I. Neugut, Dawn L. Hershman, Jeanne Mandelblatt, Michael P. Pelayo, Allegra W. Timperi, Sunita Q. Miles, Lawrence H. Kushi

Epidemiology

Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women’s Health Study

Edward A. Ruiz-Narvaez, Lynn Rosenberg, Charles N. Rotimi, L. Adrienne Cupples, Deborah A. Boggs, Adebowale Adeyemo, Yvette C. Cozier, Lucile L. Adams-Campbell, Julie R. Palmer

Epidemiology

Past recreational physical activity, body size, and all-cause mortality following breast cancer diagnosis: results from the breast cancer family registry

Theresa H. M. Keegan, Roger L. Milne, Irene L. Andrulis, Ellen T. Chang, Meera Sangaramoorthy, Kelly-Anne Phillips, Graham G. Giles, Pamela J. Goodwin, Carmel Apicella, John L. Hopper, Alice S. Whittemore, Esther M. John

Epidemiology

Lack of association between MnSOD Val16Ala polymorphism and breast cancer risk: a meta-analysis involving 58,448 subjects

Li-Xin Qiu, Lei Yao, Chen Mao, Bo Chen, Ping Zhan, Hui Yuan, Kai Xue, Jian Zhang, Xi-Chun Hu

Epidemiology

MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls

Jian Zhang, Li-Xin Qiu, Zhong-Hua Wang, Xiang-Hua Wu, Xiao-Jian Liu, Bi-Yun Wang, Xi-Chun Hu

Epidemiology

TGFB1 L10P polymorphism is associated with breast cancer susceptibility: evidence from a meta-analysis involving 47,817 subjects

Li-Xin Qiu, Lei Yao, Chen Mao, Bo Chen, Ping Zhan, Kai Xue, Jian Zhang, Hui Yuan, Xi-Chun Hu

Brief Report

Absence of genomic BRCA1 and BRCA2 rearrangements in Ashkenazi breast and ovarian cancer families

Zsofia K. Stadler, Emmanuel Saloustros, Nichole A. L. Hansen, Alice E. Schluger, Noah D. Kauff, Kenneth Offit, Mark E. Robson

Brief Report

Identification of a new complex deleterious mutation in exon 18 of the BRCA2 gene in a hereditary male/female breast cancer family

Orland Diez, Sara Gutiérrez-Enríquez, Miriam Masas, Anna Tenés, Carme Yagüe, Angels Arcusa, Gemma Llort

Brief Report

Among women who experience a recurrence after postmastectomy radiation therapy irradiation is not associated with more aggressive local recurrence or reduced survival

Wendy A. Woodward, Pauline T. Truong, Tse-Kuan Yu, Welela Tereffe, Julia Oh, George Perkins, Eric Strom, Funda Meric-Bernstam, Ana-Maria Gonzalez-Angulo, Caroline Speers, Joseph Ragaz, Thomas A. Buchholz

Letter to the Editor

RAD50 gene mutations are not likely a risk factor for breast cancer in Poland

Maria Mosor, Iwona Ziółkowska-Suchanek, Krzysztof Rożnowski, Marta Baranowska, Danuta Januszkiewicz-Lewandowska, Jerzy Nowak

Letter to the Editor

Expression of the stem cell marker ALDH1 in the normal breast of BRCA1 mutation carriers

Marise R. Heerma van Voss, Petra van der Groep, Joost Bart, Elsken van der Wall, Paul J. van Diest

Update Onkologie

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