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Breast Cancer Research and Treatment

Ausgabe 3/2012

Inhalt (38 Artikel)

Review

Case report and review of the literature: Secretory breast cancer in a 13-year-old boy—10 years of follow up

Cesar Cabello, Marcelo Alvarenga, Cesar Augusto Alvarenga, Giuliano Mendes Duarte, Patrick Nunes Pereira, Priscila Silva Marshall

Open Access Review

Beyond taxanes: the next generation of microtubule-targeting agents

Javier Cortes, Maria Vidal

Review

Locoregional recurrence after breast cancer surgery: a systematic review by receptor phenotype

Aoife J. Lowery, Malcolm R. Kell, Ronan W. Glynn, Michael J. Kerin, Karl J. Sweeney

Preclinical study

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes

Muhammad Riaz, Els M. J. J. Berns, Anieta M. Sieuwerts, Kirsten Ruigrok-Ritstier, Vanja de Weerd, Arwin Groenewoud, Andrè G. Uitterlinden, Maxime P. Look, Jan G. M. Klijn, Stefan Sleijfer, John A. Foekens, John W. M. Martens

Preclinical study

Triggering of Toll-like receptor 4 on metastatic breast cancer cells promotes αvβ3-mediated adhesion and invasive migration

Sheng-Jun Liao, Yuan-Hong Zhou, Ye Yuan, Dong Li, Feng-Hua Wu, Qi Wang, Jian-Hua Zhu, Bin Yan, Jing-Jing Wei, Gui-Mei Zhang, Zuo-Hua Feng

Open Access Preclinical Study

Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival

Victor J. Weigman, Hann-Hsiang Chao, Andrey A. Shabalin, Xiaping He, Joel S. Parker, Silje H. Nordgard, Tatyana Grushko, Dezheng Huo, Chika Nwachukwu, Andrew Nobel, Vessela N. Kristensen, Anne-Lise Børresen-Dale, Olufunmilayo I. Olopade, Charles M. Perou

Preclinical Study

Differential oxidative status and immune characterization of the early and advanced stages of human breast cancer

C. Panis, V. J. Victorino, A. C. S. A. Herrera, L. F. Freitas, T. De Rossi, F. C. Campos, A. N. Colado Simão, D. S. Barbosa, P. Pinge-Filho, R. Cecchini, A. L. Cecchini

Preclinical study

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma

Clint E. Johnson, Kylie L. Gorringe, Ella R. Thompson, Ken Opeskin, Samantha E. Boyle, Yuker Wang, Prue Hill, G. Bruce Mann, Ian G. Campbell

Preclinical Study

Local treatment of mixed osteolytic/osteoblastic spinal metastases: is photodynamic therapy effective?

L. Wise-Milestone, M. K. Akens, V. C. K. Lo, A. J. Yee, B. C. Wilson, C. M. Whyne

Preclinical Study

Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer

Jin Cheon Kim, Jong Han Yu, Yoon Kyung Cho, Choon Sik Jung, Sei Hyun Ahn, Gyungyub Gong, Yong Sung Kim, Dong-Hyung Cho

Preclinical study

Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction

M. Luz Flores, Carolina Castilla, Rainiero Ávila, Manuel Ruiz-Borrego, Carmen Sáez, Miguel A. Japón

Preclinical study

Topoisomerase 2A gene amplification in breast cancer. Critical evaluation of different FISH probes

Zsuzsanna Varga, Cathy B. Moelans, Ursina Zuerrer-Hardi, Constanze Ramach, Silvia Behnke, Glen Kristiansen, Holger Moch

Open Access Preclinical Study

High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer

M. P. H. M. Jansen, E. A. Reijm, A. M. Sieuwerts, K. Ruigrok-Ritstier, M. P. Look, F. G. Rodríguez-González, A. A. J. Heine, J. W. Martens, S. Sleijfer, J. A. Foekens, E. M. J. J. Berns

Preclinical Study

A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

Abeer M. Shaaban, Graham R. Ball, Rebecca A. Brannan, Gabor Cserni, Anna Di Benedetto, Jo Dent, Laura Fulford, Helen Honarpisheh, Lee Jordan, J. Louise Jones, Rani Kanthan, Loaie Maraqa, Maria Litwiniuk, Marcella Mottolese, Steven Pollock, Elena Provenzano, Philip R. Quinlan, Georgina Reall, Sami Shousha, Mark Stephens, Eldo T. Verghese, Rosemary A. Walker, Andrew M. Hanby, Valerie Speirs

Preclinical study

An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression

Natalie E. Simpson, Volodymyr P. Tryndyak, Frederick A. Beland, Igor P. Pogribny

Preclinical Study

Investigation of human JC and BK polyomaviruses in breast carcinomas

Mohamed Hachana, Khaled Amara, Sonia Ziadi, Riadh Ben Gacem, Sadok Korbi, Mounir Trimeche

Preclinical study

A CD44−/CD24+ phenotype is a poor prognostic marker in early invasive breast cancer

Mohamed A. H. Ahmed, Mohammed A. Aleskandarany, Emad A. Rakha, Radwa Z. A. Moustafa, Ahmed Benhasouna, Christopher Nolan, Andrew R. Green, Mohammad Ilyas, Ian O. Ellis

Preclinical Study

Associated expressions of FGFR-2 and FGFR-3: from mouse mammary gland physiology to human breast cancer

Juan P. Cerliani, Silvia I. Vanzulli, Cecilia Pérez Piñero, María C. Bottino, Ana Sahores, Myriam Nuñez, Romina Varchetta, Rubén Martins, Eduardo Zeitlin, Stephen M. Hewitt, Alfredo A. Molinolo, Claudia Lanari, Caroline A. Lamb

Preclinical Study

Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia

Erik S. Knudsen, Adam Ertel, Elai Davicioni, Jessica Kline, Gordon F. Schwartz, Agnieszka K. Witkiewicz

Preclinical study

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells

Adele Vivacqua, Enrica Romeo, Paola De Marco, Ernestina Marianna De Francesco, Sergio Abonante, Marcello Maggiolini

Preclinical Study

Ethanol promotes mammary tumor growth and angiogenesis: the involvement of chemoattractant factor MCP-1

Siying Wang, Mei Xu, Feifei Li, Xin Wang, Kimberly A. Bower, Jacqueline A. Frank, Yanmin Lu, Gang Chen, Zhuo Zhang, Zunji Ke, Xianglin Shi, Jia Luo

Open Access Clinical Trial

A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab

Nancy U. Lin, Eric P. Winer, Duncan Wheatley, Lisa A. Carey, Stephen Houston, David Mendelson, Pamela Munster, Laurie Frakes, Steve Kelly, Agustin A. Garcia, Susan Cleator, Martina Uttenreuther-Fischer, Hilary Jones, Sven Wind, Richard Vinisko, Tamas Hickish

Clinical trial

Second-line bevacizumab-containing therapy in patients with triple-negative breast cancer: subgroup analysis of the RIBBON-2 trial

Adam Brufsky, Vicente Valero, Beatrice Tiangco, Shaker Dakhil, Arija Brize, Hope S. Rugo, Ragene Rivera, Anja Duenne, Naima Bousfoul, Denise A. Yardley

Open Access Clinical trial

25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1

Eitan Amir, Reena S. Cecchini, Patricia A. Ganz, Joseph P. Costantino, Samantha Beddows, Nicola Hood, Pamela J. Goodwin

Clinical trial

Recommendations for antiresorptive therapy in postmenopausal patients with breast cancer: Marburg AIBL Guideline Evaluation Study (MAGES)

Peyman Hadji, Melanie Hartenfels, Jannis Kyvernitakis, Olaf Hars, Klaus Heinrich Baumann, Matthias Kalder

Epidemiology

Family history and risk of breast cancer: nurses’ health study

Graham A. Colditz, Kimberly A. Kaphingst, Susan E. Hankinson, Bernard Rosner

Epidemiology

Association of CD27 and CD70 gene polymorphisms with risk of sporadic breast cancer in Chinese women in Heilongjiang Province

Fengyan Xu, Dalin Li, Qiujin Zhang, Zhenkun Fu, Weiguang Yuan, Da Pang, Dianjun Li

Epidemiology

Cost-utility of the 21-gene recurrence score assay in node-negative and node-positive breast cancer

Nathan W. D. Lamond, Chris Skedgel, Daniel Rayson, Lynn Lethbridge, Tallal Younis

Epidemiology

Breast cancer phenotype in women with TP53 germline mutations: a Li-Fraumeni syndrome consortium effort

Serena Masciari, Deborah A. Dillon, Michelle Rath, Mark Robson, Jeffrey N. Weitzel, Judith Balmana, Stephen B. Gruber, James M. Ford, David Euhus, Alexandra Lebensohn, Melinda Telli, Stephen M. Pochebit, Georgios Lypas, Judy E. Garber

Epidemiology

Biologic features and prognosis of ductal carcinoma in situ are not adversely impacted by initial large body mass

Henry M. Kuerer, Sara A. Lari, Banu K. Arun, Chung-Yuan Hu, Abenaa Brewster, Elizabeth A. Mittendorf, Constance T. Albarracin, Gildy V. Babiera, Abigail S. Caudle, Jamie L. Wagner, Jennifer K. Litton, Isabelle Bedrosian, Funda Meric-Bernstam, Anthony Lucci, Kelly K. Hunt

Open Access Epidemiology

Prevalence of BRCA1 and BRCA2 mutations in non-familial breast cancer patients with high risks in Korea: The Korean Hereditary Breast Cancer (KOHBRA) Study

Byung Ho Son, Sei Hyun Ahn, Sung-Won Kim, Eunyoung Kang, Sue K. Park, Min Hyuk Lee, Woo-Chul Noh, Lee Su Kim, Yongsik Jung, Ku Sang Kim, Dong-Young Noh, Byung-In Moon, Young Jin Suh, Jeong Eon Lee, Doo Ho Choi, Sung Yong Kim, Sung Hoo Jung, Cha Kyong Yom, Hyde Lee, Jung-Hyun Yang

Epidemiology

Recurrent germline mutations in BRCA1 and BRCA2 genes in high risk families in Israel

Yael Laitman, Monica Simeonov, Liron Herskovitz, Anya Kushnir, Shani Shimon-Paluch, Bella Kaufman, Jamal Zidan, Eitan Friedman

Epidemiology

Vitamin D threshold to prevent aromatase inhibitor-related bone loss: the B-ABLE prospective cohort study

Daniel Prieto-Alhambra, Sonia Servitja, M. Kassim Javaid, Laia Garrigós, Nigel K. Arden, Cyrus Cooper, Joan Albanell, Ignasi Tusquets, Adolfo Diez-Perez, Xavier Nogues

Epidemiology

Benign thyroid disease is associated with breast cancer: a meta-analysis

Prue J. Hardefeldt, Guy D. Eslick, Senarath Edirimanne

Brief Report

Rare germline large rearrangements in the BRCA1/2 genes and eight candidate genes in 472 patients with breast cancer predisposition

E. Rouleau, B. Jesson, A. Briaux, C. Nogues, V. Chabaud, L. Demange, J. Sokolowska, F. Coulet, E. Barouk-Simonet, Y. J. Bignon, F. Bonnet, V. Bourdon, M. Bronner, S. Caputo, L. Castera, C. Delnatte, C. Delvincourt, J. Fournier, A. Hardouin, D. Muller, J. P. Peyrat, C. Toulas, N. Uhrhammer, V. Vidal, D. Stoppa-Lyonnet, I. Bieche, R. Lidereau

Brief Report

Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients

Roberta Ferraldeschi, Monica Arnedos, Kristen D. Hadfield, Roger A’Hern, Suzie Drury, Andrew Wardley, Anthony Howell, D. Gareth Evans, Stephen A. Roberts, Ian Smith, William G. Newman, Mitch Dowsett

Brief Report

The biological correlates of macroscopic breast tumour structure measured using fractal analysis in patients undergoing neoadjuvant chemotherapy

P. Di Giovanni, T. S. Ahearn, S. I. K. Semple, L. M. Lovell, I. Miller, F. J. Gilbert, T. W. Redpath, S. D. Heys, R. T. Staff

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