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Erschienen in: Aesthetic Plastic Surgery 5/2018

11.06.2018 | Original Article

Breast-Conserving Surgery with Immediate Autologous Fat Grafting Reconstruction: Oncologic Outcomes

verfasst von: Jorge Villanova Biazus, Camile Cesa Stumpf, Marcia Portela Melo, Angela Erguy Zucatto, Rodrigo Cericatto, Jose Antonio Cavalheiro, Andrea Pires Damin

Erschienen in: Aesthetic Plastic Surgery | Ausgabe 5/2018

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Abstract

Introduction

Autologous fat grafting (AFG; lipofilling, lipografting) has been used in delayed breast reconstruction. Recently, it has also been investigated as an alternative for immediate reconstruction in patients submitted to breast-conserving surgery (BCS). Although good aesthetic results have been reported, the oncologic safety of the procedure remains under investigation. This article aims to assess oncologic outcomes of patients submitted to BCS with immediate AFG reconstruction.

Methods

This study consisted of 65 patients undergoing BCS with AFG between January 2010 and January 2017. They were closely followed after surgery for a median period of 40.8 months. Locoregional and systemic recurrences were the primary endpoints of this study.

Results

Ten patients developed cancer recurrence (15.4%). The median time for recurrence was 58.9 months. Only two patients presented locoregional recurrence (LRR) (3.07%). Five patients had systemic recurrence (7.69%), and three had both systemic and LRR (4.61%). Median disease-free survival (DFS) was 42.2 months, and overall survival (OV) was 44.3 months. Recurrences were significantly associated with the number of metastatic axillary lymph nodes detected.

Conclusion

Oncologic outcomes of immediate AFG are similar to the results previously reported in BCS without AFG. Locoregional and systemic recurrences are associated with the presence of axillary metastases.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
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Metadaten
Titel
Breast-Conserving Surgery with Immediate Autologous Fat Grafting Reconstruction: Oncologic Outcomes
verfasst von
Jorge Villanova Biazus
Camile Cesa Stumpf
Marcia Portela Melo
Angela Erguy Zucatto
Rodrigo Cericatto
Jose Antonio Cavalheiro
Andrea Pires Damin
Publikationsdatum
11.06.2018
Verlag
Springer US
Erschienen in
Aesthetic Plastic Surgery / Ausgabe 5/2018
Print ISSN: 0364-216X
Elektronische ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-018-1155-5

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