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01.12.2018 | Case Report | Ausgabe 1/2018 Open Access

Diagnostic Pathology 1/2018

Breast implant-associated anaplastic large cell lymphoma in a Li-FRAUMENI patient: a case report

Zeitschrift:
Diagnostic Pathology > Ausgabe 1/2018
Autoren:
Ricardo Garcia Pastorello, Felipe D’Almeida Costa, Cynthia A. B. T. Osório, Fabiana B. A. Makdissi, Stephania Martins Bezerra, Marina de Brot, Antonio Hugo J. F. M. Campos, Fernando Augusto Soares, José Vassallo

Abstract

Background

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare malignancy, recently recognized as a provisional entity by the World Health Organization. Although increasing data have been published on this entity in recent years, a great number of patients and health professionals remain unaware of this diagnosis.

Case presentation

We herein report the case of a 56-year-old female with Li-FRAUMENI syndrome who presented with late right-sided recurrent breast swelling after prophylactic adenomastectomy with implant reconstruction. Imaging scans revealed an heterogeneous mass adjacent to the implant fibrous capsule. A biopsy of the lesion rendered the diagnosis of a BIA-ALCL.

Conclusions

This case presents similarities with previous reports, but also some particularities, which should be stressed in order to make the diagnosis the earliest possible. The most distinct feature is that this is the second report of BIA-ALCL arising in the setting of Li-FRAUMENI syndrome.
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