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Archives of Virology
Erschienen in: Archives of Virology 3/2017

28.11.2016 | Review

Broad-spectrum antiviral properties of andrographolide

verfasst von: Swati Gupta, K. P. Mishra, Lilly Ganju

Erschienen in: Archives of Virology | Ausgabe 3/2017

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Abstract

Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated from various plants of the genus Andrographis, commonly known as ‘creat’. This purified compound has been tested for its anti-inflammatory effects in various stressful conditions, such as ischemia, pyrogenesis, arthritis, hepatic or neural toxicity, carcinoma, and oxidative stress, Apart from its anti-inflammatory effects, andrographolide also exhibits immunomodulatory effects by effectively enhancing cytotoxic T cells, natural killer (NK) cells, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). All these properties of andrographolide form the foundation for the use of this miraculous compound to restrain virus replication and virus-induced pathogenesis. The present article covers antiviral properties of andrographolide in variety of viral infections, with the hope of developing of a new highly potent antiviral drug with multiple effects.
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Metadaten
Titel
Broad-spectrum antiviral properties of andrographolide
verfasst von
Swati Gupta
K. P. Mishra
Lilly Ganju
Publikationsdatum
28.11.2016
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 3/2017
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-3166-3

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