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Zeitschrift

Calcified Tissue International

and Musculoskeletal Research

Calcified Tissue International OnlineFirst articles

10.02.2020 | Case Reports

Fragile Bones Secondary to SMURF1 Gene Duplication

Studies on mice have shown that the Smad Ubiquitin Regulatory Factor-1 (SMURF1) gene negatively regulates osteoblast function and the response to bone morphogenetic protein in a dose-dependent fashion (Chan et al. in Mol Cell Biol …

07.02.2020 | Letter to the Editor

The Latest Evidence from Vitamin D Intervention Trials for Non-skeletal Outcomes

06.02.2020 | Original Research

Sclerostin-Antibody Treatment Decreases Fracture Rates in Axial Skeleton and Improves the Skeletal Phenotype in Growing oim/oim Mice

In osteogenesis imperfecta (OI), vertebrae brittleness causes thorax deformations and leads to cardiopulmonary failure. As sclerostin-neutralizing antibodies increase bone mass and strength in animal models of osteoporosis, their administration in …

01.02.2020 | Original Research

New Function of RUNX2 in Regulating Osteoclast Differentiation via the AKT/NFATc1/CTSK Axis

Cleidocranial dysplasia is an autosomal dominant skeletal disorder resulting from RUNX2 mutations. The influence of RUNX2 mutations on osteoclastogenesis and bone resorption have not been reported. To investigate the role of RUNX2 in osteoclast …

29.01.2020 | Original Research

Bone Growth is Influenced by Fructose in Adolescent Male Mice Lacking Ketohexokinase (KHK)

Fructose is metabolized in the cytoplasm by the enzyme ketohexokinase (KHK), and excessive consumption may affect bone health. Previous work in calcium-restricted, growing mice demonstrated that fructose disrupted intestinal calcium transport.

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Über diese Zeitschrift

Calcified Tissue International was founded in 1967 under the name Calcified Tissue Research. Vols. 1-19 were edited by B.E.C. Nordin, F.G.E. Pautard, D. B. Scott, B.A. Friedman; Vols. 20-22 by B.E.C. Nordin, F.G.E. Pautard, B.A. Friedman, L. Klein; Vols. 23-24 by W.D. Armstrong. Beginning with Vol. 27 in 1979, the journal was renamed Calcified Tissue International and was edited by L. V. Avioli until 1999. Vols. 66-75, were then co-edited by Drs. R. Civitelli, K.A. Hruska, and S. Ralston. Vols. 76-92, were co-edited by Drs. R. Civitelli and S.H. Ralston. Since Vol. 93 the journal, which was renamed Calcified Tissue International and Musculoskeletal Research has been co-edited by Drs. S.H. Ralston and R. Rizzoli.

The Journal serves as a forum to explore the biochemical, biophysical, molecular, and genetic determinants of the structure, function, and metabolism of bone, and other musculoskeletal tissues in living organisms. It publishes preclinical and translational research on these topics as well as clinical research in humans of relevance to gaining greater understanding of the pathogenesis and treatment of bone disease and other diseases of the musculoskeletal system including musculoskeletal interactions.

Weitere Informationen

Neu im Fachgebiet Innere Medizin

Meistgelesene Bücher aus der Inneren Medizin

2017 | Buch

Rheumatologie aus der Praxis

Entzündliche Gelenkerkrankungen – mit Fallbeispielen

Dieses Fachbuch macht mit den wichtigsten chronisch entzündlichen Gelenk- und Wirbelsäulenerkrankungen vertraut. Anhand von über 40 instruktiven Fallbeispielen werden anschaulich diagnostisches Vorgehen, therapeutisches Ansprechen und der Verlauf …

Herausgeber:
Rudolf Puchner

2016 | Buch

Ambulant erworbene Pneumonie

Was, wann, warum – Dieses Buch bietet differenzierte Diagnostik und Therapie der ambulant erworbenen Pneumonie zur sofortigen sicheren Anwendung. Entsprechend der neuesten Studien und Leitlinien aller wichtigen Fachgesellschaften.

Herausgeber:
Santiago Ewig

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