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Calcified Tissue International

and Musculoskeletal Research

Calcified Tissue International OnlineFirst articles

24.07.2021 | Editorial

Calibration of FRAX: A Journey, not a Destination

William Leslie has no conflicts of interest. John A Kanis reports grants from Amgen, Eli Lilly and Radius Health and consulting fees from Theramex. JAK is the architect of FRAX® but has no financial interest.

24.07.2021 | Original Research

Vascular Complications in Individuals with Type 2 Diabetes Mellitus Additionally Increase the Risk of Femoral Neck Fractures Due to Deteriorated Trabecular Microarchitecture

Individuals with diabetes mellitus type 2 (T2DM) have an increased risk of hip fracture, especially if vascular complications are present. However, microstructural origins of increased bone fragility in T2DM are still controversial. DXA …

14.07.2021 | Original Research Open Access

Depression and Osteoporosis: A Mendelian Randomization Study

Observational studies suggest a link between depression and osteoporosis, but these may be subject to confounding and reverse causality. In this two-sample Mendelian randomization analysis, we included the large meta-analysis of genome-wide …

10.07.2021 | Original Research Open Access

Acute Phase Reactions After Intravenous Infusion of Zoledronic Acid in Japanese Patients with Osteoporosis: Sub-analyses of the Phase III ZONE Study

In a clinical trial involving Japanese patients with osteoporosis, post hoc analyses were performed to evaluate the incidence of acute phase reactions (APRs) after infusion of zoledronic acid (ZOL). The results highlighted differences in baseline …

10.07.2021 | Original Research

Fibroblast Growth Factor 2 High Molecular Weight Isoforms in Dentoalveolar Mineralization

Transgenic mice overexpressing human high molecular weight fibroblast growth factor 2 (HMWFGF2) isoforms in osteoblast and odontoblast lineages (HMWTg) exhibit decreased dentin and alveolar bone mineralization, enlarged pulp chamber, and increased …

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Über diese Zeitschrift

Calcified Tissue International was founded in 1967 under the name Calcified Tissue Research. Vols. 1-19 were edited by B.E.C. Nordin, F.G.E. Pautard, D. B. Scott, B.A. Friedman; Vols. 20-22 by B.E.C. Nordin, F.G.E. Pautard, B.A. Friedman, L. Klein; Vols. 23-24 by W.D. Armstrong. Beginning with Vol. 27 in 1979, the journal was renamed Calcified Tissue International and was edited by L. V. Avioli until 1999. Vols. 66-75, were then co-edited by Drs. R. Civitelli, K.A. Hruska, and S. Ralston. Vols. 76-92, were co-edited by Drs. R. Civitelli and S.H. Ralston. Since Vol. 93 the journal, which was renamed Calcified Tissue International and Musculoskeletal Research has been co-edited by Drs. S.H. Ralston and R. Rizzoli.

The Journal serves as a forum to explore the biochemical, biophysical, molecular, and genetic determinants of the structure, function, and metabolism of bone, and other musculoskeletal tissues in living organisms. It publishes preclinical and translational research on these topics as well as clinical research in humans of relevance to gaining greater understanding of the pathogenesis and treatment of bone disease and other diseases of the musculoskeletal system including musculoskeletal interactions.

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