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Calcified Tissue International OnlineFirst articles

27.11.2022 | Original Research

Comparing the Fracture Profile of Osteosarcopenic Older Adults with Osteopenia/Osteoporosis Alone

The dual concept of osteopenia/osteoporosis and sarcopenia, termed osteosarcopenia [ 1 , 2 ], has gained significant traction in recent years due to their shared risk factors [ 3 ] and frequent coexistence in older adults [ 4 ]. Osteosarcopenia …

24.11.2022 | Review Article

From Stem to Sternum: The Role of Shp2 in the Skeleton

Src homology-2 domain-containing phosphatase 2 (SHP2) is a ubiquitously expressed phosphatase that is vital for skeletal development and maintenance of chondrocytes, osteoblasts, and osteoclasts. Study of SHP2 function in small animal models has …

Open Access 21.11.2022 | Original Research

Effects of Infantile Hypophosphatasia on Human Dental Tissue

Hypophosphatasia (HPP) is an inherited, systemic disorder, caused by loss-of-function variants of the ALPL gene encoding the enzyme tissue non-specific alkaline phosphatase (TNSALP). HPP is characterized by low serum TNSALP concentrations …

13.11.2022 | Case Reports

Combined Thermoneutral Housing and Raloxifene Treatment Improves Trabecular Bone Microarchitecture and Strength in Growing Female Mice

Thermoneutral housing and Raloxifene (RAL) treatment both have potential for improving mechanical and architectural properties of bone. Housing mice within a 30 to 32 °C range improves bone quality by reducing the consequences of cold stress, such …

10.11.2022 | Original Research

Three-Dimensional Analysis of the Trapezium Subchondral Bone and its Association with Trapeziometacarpal Joint Osteoarthritis

Subchondral bone properties are associated with the pathogenesis of osteoarthritis (OA), but this relationship has not been confirmed in the trapeziometacarpal joint (TMCJ). We aimed to evaluate the thickness (SBT) and density (SBD) of …

Über diese Zeitschrift

Calcified Tissue International was founded in 1967 under the name Calcified Tissue Research. Vols. 1-19 were edited by B.E.C. Nordin, F.G.E. Pautard, D. B. Scott, B.A. Friedman; Vols. 20-22 by B.E.C. Nordin, F.G.E. Pautard, B.A. Friedman, L. Klein; Vols. 23-24 by W.D. Armstrong. Beginning with Vol. 27 in 1979, the journal was renamed Calcified Tissue International and was edited by L. V. Avioli until 1999. Vols. 66-75, were then co-edited by Drs. R. Civitelli, K.A. Hruska, and S. Ralston. Vols. 76-92, were co-edited by Drs. R. Civitelli and S.H. Ralston. Since Vol. 93 the journal, which was renamed Calcified Tissue International and Musculoskeletal Research has been co-edited by Drs. S.H. Ralston and R. Rizzoli.

The Journal serves as a forum to explore the biochemical, biophysical, molecular, and genetic determinants of the structure, function, and metabolism of bone, and other musculoskeletal tissues in living organisms. It publishes preclinical and translational research on these topics as well as clinical research in humans of relevance to gaining greater understanding of the pathogenesis and treatment of bone disease and other diseases of the musculoskeletal system including musculoskeletal interactions.

Calcified Tissue International
Volume 60/1997 - Volume 111/2022
Springer US
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