Background
Methods
QT interval measures and cardiac enzymes
Statistical analysis
Results
Patients
Male sex (%) | 42 patients (60%) |
Age (mean ± SD) | 51.6 ± 18.2 years |
Smoker | 26 patients (37.1%) |
Hypertension | 10 patients (14.3%) |
Diabetes mellitus | 4 patients (5.7%) |
Asymptomatic patients (%) | 23 patients (33%) |
Consciousness disorder on admission (%) | 37 patients (53%) |
Cardiopulmonary arrest (%) | 3 patients (4%) |
Hyperbaric oxygen therapy (%) | 49 patients (70%) |
Sequential disability (%) | 15 patients (21%) |
Deliberately carbon monoxide exposed patients (%) | 20 patients (29%) |
Carboxyhemoglobin level (%) (normal range 0.5–1.5) | 21.8 ± 14.8 |
Troponin I (ng/ml) (normal range 0.00–0.09) | 0.85 ± 3.36 |
Mean emergency department arrival time (min) | 165 ± 148 |
Correlation between carboxyhemoglobin and QT intervals
Comparison between patients with and without a sequential disability
Sequential disability (+) n = 15 | Sequential Disability (−) n = 55 | p | |
---|---|---|---|
Sex (Male: %) | 67% (n = 10) | 58% (n = 32) | 0.5521 |
Smoker | 20% (n = 3) | 42% (n = 23) | 0.1211 |
Hypertension | 0% (n = 0) | 18% (n = 0) | 0.0745 |
Diabetes mellitus | 0% (n = 0) | 7% (n = 4) | 0.2821 |
Consciousness disorder on admission | 80% (n = 12) | 38%(n = 21) | 0.0040 |
Cardiopulmonary arrest | 20% (n = 3) | 0% (n = 0) | 0.0083 |
Deliberately carbon monoxide exposed patients | 47% (n = 7) | 24% (n = 13) | 0.0801 |
Hyperbaric oxygen therapy | 60% (n = 9) | 72% (n = 40) | 0.3404 |
Hypokalemia | 20% (n = 3) | 16% (n = 9) | 0.7405 |
Minor tranquilizer | 13% (n = 2) | 13% (n = 7) | 0.9504 |
Major tranquilizer | 7% (n = 1) | 5% (n = 3) | 0.8577 |
Antidepressant | 7% (n = 4) | 7% (n = 1) | 0.9356 |
Other drugs | 27% (n = 4) | 29% (n = 16) | 0.8538 |
Age (years) | 53.9 ± 17.3 | 51.0 ± 18.5 | 0.5895 |
Mean emergency department arrival time | 199.5 ± 192.0 min | 156.0 ± 134.1 min | 0.3159 |
Maximum QT interval (msec) | 395.7 ± 54.1 | 370.6 ± 32.6 | 0.0269 |
Maximum QTc interval (msec) | 482.6 ± 63.4 | 435.7 ± 32.1 | 0.0002 |
QT dispersion (msec) | 54.8 ± 35.6 | 25.0 ± 23.6 | 0.0003 |
QTc dispersion (msec) | 64.1 ± 35.4 | 29.3 ± 27.3 | 0.0001 |
Carboxy hemoglobin level (%) | 27.1 ± 17.3 | 20.3 ± 13.7 | 0.1089 |
Troponin I (ng/ml) | 2.4 ± 5.5 | 0.4 ± 2.4 | 0.0471 |
Nominal logistic analyses
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Odds ratio (95% CI) | p | Odds ratio (95% CI) | p | |
Sex (M) | 1.4375 (0.433–4.772) | 0.5533 | ||
Age (> 30) | 1.714 (0.190–15.452) | 0.6309 | ||
Smoker | 0.3478 (0.088–1.374) | 0.1319 | ||
Consciousness disorder | 6.476 ((1.634–25.669) | 0.0078 | ||
Hyperbaric oxygen therapy | 0.563 (0.171–1.851) | 0.3493 | ||
QTc dispersion (> 46 msec) | 12.375 (3.260–46.970) | 0.0002 | 12.333 (2.207–68.926) | 0.0042 |
Carboxyhemoglobin level (> 44%) | 8.666 (1.779–42.215) | 0.0044 | 3.863 (0.433–34.467) | 0.2262 |
Troponin I (> 0.36 ng/ml) | 14.571 (3.463–61.311) | 0.0003 | 19.709 (2.947–131.770) | 0.0021 |