Ausgabe 3/2019
Proteases in Cancer Progression and Metastasis
Inhalt (16 Artikel)
Beyond the biomarker role: prostate-specific antigen (PSA) in the prostate cancer microenvironment
Afshin Moradi, Srilakshmi Srinivasan, Judith Clements, Jyotsna Batra
Role of meprin metalloproteases in metastasis and tumor microenvironment
Florian Peters, Christoph Becker-Pauly
Cell surface–anchored serine proteases in cancer progression and metastasis
Carly E. Martin, Karin List
Differential roles of protease isoforms in the tumor microenvironment
Chamikara Liyanage, Achala Fernando, Jyotsna Batra
Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors
Holger Bronger, Viktor Magdolen, Peter Goettig, Tobias Dreyer
The role of proteases in epithelial-to-mesenchymal cell transitions in cancer
Julia Mitschke, Ulrike C. Burk, Thomas Reinheckel
Spatio-temporal modeling and live-cell imaging of proteolysis in the 4D microenvironment of breast cancer
Kyungmin Ji, Mansoureh Sameni, Kingsley Osuala, Kamiar Moin, Raymond R. Mattingly, Bonnie F. Sloane
Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression
Alakesh Das, Vishnu Mohan, Venkat Raghavan Krishnaswamy, Inna Solomonov, Irit Sagi
Functional disparities within the TIMP family in cancer: hints from molecular divergence
Celina Eckfeld, Daniel Häußler, Benjamin Schoeps, Chris D. Hermann, Achim Krüger
The plasminogen activator inhibitor-1 paradox in cancer: a mechanistic understanding
Marta Helena Kubala, Yves Albert DeClerck
KISS1 in breast cancer progression and autophagy
Ilya V. Ulasov, Anton V. Borovjagin, Peter Timashev, Massimo Cristofanili, Danny R. Welch
Specifically targeting cancer proliferation and metastasis processes: the development of matriptase inhibitors
Ke Zuo, Yingying Qi, Cai Yuan, Longguang Jiang, Peng Xu, Jianping Hu, Mingdong Huang, Jinyu Li
Current management of succinate dehydrogenase–deficient gastrointestinal stromal tumors
Pushpa Neppala, Sudeep Banerjee, Paul T. Fanta, Mayra Yerba, Kevin A. Porras, Adam M. Burgoyne, Jason K. Sicklick
Update on gastric cancer treatments and gene therapies
Alessio Biagioni, Ileana Skalamera, Sara Peri, Nicola Schiavone, Fabio Cianchi, Elisa Giommoni, Lucia Magnelli, Laura Papucci