Cancer and Metastasis Reviews

Editorial

Kenneth V. Honn, Avraham Raz

Biography—Henry H.Q. Heng

Preface

Henry H. Heng

Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution

Henry H. Heng, Steven W. Bremer, Joshua B. Stevens, Steven D. Horne, Guo Liu, Batoul Y. Abdallah, Karen J. Ye, Christine J. Ye

The detection and implication of genome instability in cancer

Larissa Pikor, Kelsie Thu, Emily Vucic, Wan Lam

Do mutator mutations fuel tumorigenesis?

Edward J. Fox, Marc J. Prindle, Lawrence A. Loeb

Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis

Laura L. Thompson, Brent J. Guppy, Laryssa Sawchuk, James R. Davie, Kirk J. McManus

Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos

Tamara A. Potapova, Jin Zhu, Rong Li

Chromosomal instability and transcriptome dynamics in cancer

Joshua B. Stevens, Steven D. Horne, Batoul Y. Abdallah, Christine J. Ye, Henry H. Heng

Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and “swarm intelligence”

M. Tarabichi, A. Antoniou, M. Saiselet, J. M. Pita, G. Andry, J. E. Dumont, V. Detours, C. Maenhaut

Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells

Sui Huang

The pre-metastatic niche: finding common ground

Jaclyn Sceneay, Mark J. Smyth, Andreas Möller

The targeted therapy revolution in neuroendocrine tumors: in search of biomarkers for patient selection and response evaluation

Sara De Dosso, Enrique Grande, Jorge Barriuso, Daniel Castellano, Josep Tabernero, Jaume Capdevila

Personalized radiation therapy and biomarker-driven treatment strategies: a systematic review

Jean-Emmanuel Bibault, Ingrid Fumagalli, Charles Ferté, Cyrus Chargari, Jean-Charles Soria, Eric Deutsch

Tumor type-specific and skin region-selective metastasis of human cancers: another example of the “seed and soil” hypothesis

K. A. Kovács, B. Hegedus, I. Kenessey, J. Tímár

Dormancy in solid tumors: implications for prostate cancer

Nazanin S. Ruppender, Colm Morrissey, Paul H. Lange, Robert L. Vessella

Functions, divergence and clinical value of TAp73 isoforms in cancer

Stella Logotheti, Athanasia Pavlopoulou, Sotiris Galtsidis, Borek Vojtesek, Vassilis Zoumpourlis

The role of tumour-associated MUC1 in epithelial ovarian cancer metastasis and progression

Junli Deng, Li Wang, Hongmin Chen, Lei Li, Yiming Ma, Jie Ni, Yong Li

Role of the host stroma in cancer and its therapeutic significance

David Tarin

Targeting MAPK pathway in melanoma therapy

Yabin Cheng, Guohong Zhang, Gang Li

Stromal expression of SPARC in pancreatic adenocarcinoma

Cindy Neuzillet, Annemilaï Tijeras-Raballand, Jérôme Cros, Sandrine Faivre, Pascal Hammel, Eric Raymond

Central and peripheral nervous systems: master controllers in cancer metastasis

Ming Shi, Dan Liu, Zhengyan Yang, Ning Guo

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

Asfar S. Azmi, Bin Bao, Fazlul H. Sarkar

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis

Nicole Beauchemin, Azadeh Arabzadeh

Epithelial cancers in the post-genomic era: should we reconsider our lifestyle?

Jeff M. P. Holly, Li Zeng, Claire M. Perks

Update on clinical and mechanistic aspects of paraneoplastic syndromes

David Tarin

Adverse reactions to targeted and non-targeted chemotherapeutic drugs with emphasis on hypersensitivity responses and the invasive metastatic switch

Brian A. Baldo, Nghia H. Pham

Erratum to: The role of FOXP3 in the development and metastatic spread of breast cancer

Stephen Douglass, Simi Ali, Annette P. Meeson, David Browell, John A. Kirby