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Zeitschrift

Cancer Cell International

Cancer Cell International 1/2015

Ausgabe 1/2015

Inhaltsverzeichnis ( 122 Artikel )

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Evaluating the evidence for targeting FOXO3a in breast cancer: a systematic review

Simon Taylor, Matthew Lam, Chathyan Pararasa, James EP Brown, Amtul R Carmichael, Helen R Griffiths

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Understanding the colon cancer stem cells and perspectives on treatment

Elsa N Garza-Treviño, Salvador L Said-Fernández, Herminia G Martínez-Rodríguez

01.12.2015 | Review | Ausgabe 1/2015 Open Access

The multifaceted role of CD146/MCAM in the promotion of melanoma progression

Xing Lei, Ce-Wen Guan, Yang Song, Huan Wang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells

Jing Cui, Wendong Sun, Xuexi Hao, Minli Wei, Xiaonan Su, Yajing Zhang, Ling Su, Xiangguo Liu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Antihelminthic benzimidazoles potentiate navitoclax (ABT-263) activity by inducing Noxa-dependent apoptosis in non-small cell lung cancer (NSCLC) cell lines

Lloyd T Lam, Haichao Zhang, John Xue, Joel D Leverson, Anahita Bhathena

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Chemosensitizing and nephroprotective effect of resveratrol in cisplatin –treated animals

Abdel-Moneim M Osman, Saud A Telity, Zoheir A Damanhouri, Sameer E Al-Harthy, Huda M Al-Kreathy, Wafaa S Ramadan, Mohamed F Elshal, Lateef M Khan, Fatemah Kamel

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Overview on the complexity of androgen receptor-targeted therapy for prostate cancer

Ammad Ahmad Farooqi, Fazlul H Sarkar

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The role of individual caspases in cell death induction by taxanes in breast cancer cells

Michael Jelínek, Kamila Balušíková, Martina Schmiedlová, Vlasta Němcová-Fürstová, Jan Šrámek, Jitka Stančíková, Ilaria Zanardi, Iwao Ojima, Jan Kovář

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Variant RONΔ160 of the RON receptor tyrosine kinase promotes the growth and invasion in vitro and in vivo in gastric cancer cell lines

Dong-Hui Zhou, Chao Li, Li-Na Yang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The effect of nilotinib plus arsenic trioxide on the proliferation and differentiation of primary leukemic cells from patients with chronic myoloid leukemia in blast crisis

Wei Wang, Fei-fei Lv, Yan Du, Nannan Li, YaLing Chen, LiHong Chen

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Arf6 regulates EGF-induced internalization of E-cadherin in breast cancer cells

Rui Xu, Yujie Zhang, Luo Gu, Jianchao Zheng, Jie Cui, Jing Dong, Jun Du

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Antiproliferative and apoptosis-inducing activity of schisandrin B against human glioma cells

Qun Li, Xiang-he Lu, Cheng-de Wang, Lin Cai, Jiang-long Lu, Jin-sen Wu, Qi-chuan Zhuge, Wei-ming Zheng, Zhi-peng Su

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Inhibition of the AKT pathway in cholangiocarcinoma by MK2206 reduces cellular viability via induction of apoptosis

Jacob M Wilson, Selvi Kunnimalaiyaan, Muthusamy Kunnimalaiyaan, T Clark Gamblin

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

Sybil M Genther Williams, Apryle M Kuznicki, Paula Andrade, Brian M Dolinski, Cem Elbi, Ronan C O’Hagan, Carlo Toniatti

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Galangin, a novel dietary flavonoid, attenuates metastatic feature via PKC/ERK signaling pathway in TPA-treated liver cancer HepG2 cells

Shang-Tao Chien, Ming-Der Shi, Yi-Chieh Lee, Chou-Chia Te, Yuan-Wei Shih

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Inhibition of miR-191 contributes to radiation-resistance of two lung cancer cell lines by altering autophagy activity

Zhenkuan Liu, Shaoxiang Huang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The association between expressions of Ras and CD68 in the angiogenesis of breast cancers

Wei Li, Rong-Rui Liang, Chong Zhou, Meng-Yao Wu, Lian Lian, Gao-Feng Yuan, Ming-Yun Wang, Xin Xie, Liu-Mei Shou, Fei-Ran Gong, Kai Chen, Wei-Ming Duan, Min Tao

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

RETRACTED ARTICLE: Psoriasin (S100A7) is a novel biomarker for lung squamous cell carcinoma in humans

Guijuan Liu, Qiang Wu, Guilan Liu, Xueying Song, Jihong Zhang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Kinetic characterization of lactate dehydrogenase in normal and malignant human breast tissues

Abdolhassan Talaiezadeh, Ali Shahriari, Mohammad Reza Tabandeh, Payam Fathizadeh, Siavash Mansouri

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Adenovirus-mediated co-expression of the TRAIL and HN genes inhibits growth and induces apoptosis in Marek’s disease tumor cell line MSB-1

Dongxiao Dong, Jing Gao, Ying Sun, Yuqing Long, Meng Li, Dongchao Zhang, Jianfang Gong, Liang Xu, Liuan Li, Shunyi Qin, Jifei Ma, Tianming Jin

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The association between Salt-inducible kinase 2 (SIK2) and gamma isoform of the regulatory subunit B55 of PP2A (B55gamma) contributes to the survival of glioma cells under glucose depletion through inhibiting the phosphorylation of S6K

Ya-nan Li, Yi-qun Cao, Xi Wu, Guo-sheng Han, Lai-xing Wang, Yu-hui Zhang, Xin Chen, Bin Hao, Zhi-jian Yue, Jian-min Liu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Ribonucleic acid (RNA) biosynthesis in human cancer

Omar S Hajjawi

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Differential effects of HIF-α isoforms on apoptosis in renal carcinoma cell lines

Alana Doonachar, Michael D Gallo, Donald Doukas, Rajiv Pasricha, Igor Lantsberg, Alan R Schoenfeld

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition

Jing Wang, Dengyu Chen, Xiangfeng He, Yuxia Zhang, Fangfang Shi, Di Wu, Junsong Chen, Ying Zhang, Fengsu Zhao, Jun Dou

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Deguelin induces the apoptosis of lung cancer cells through regulating a ROS driven Akt pathway

Huae Xu, Xiaolin Li, Wenqiu Ding, Xiaoning Zeng, Hui Kong, Hong Wang, Weiping Xie

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Human urothelial carcinoma cell response to Sunitinib malate therapy in vitro

Jin Wen, Han-Zhong Li, Zhi-Gang Ji, Jing Jin

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation

Xiaoyan Dou, Jing Wei, Aiqin Sun, Genbao Shao, Chandra Childress, Wannian Yang, Qiong Lin

01.12.2015 | Reviewer acknowledgement | Ausgabe 1/2015 Open Access

Thanking our 2014 reviewers

Denys Wheatley

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Transient knockdown-mediated deficiency in plectin alters hepatocellular motility in association with activated FAK and Rac1-GTPase

Chiung-Chi Cheng, Yen-Chang Clark Lai, Yih-Shyong Lai, Yung-Hsiang Hsu, Wei-Ting Chao, Kee-Chin Sia, Yu-Hui Tseng, Yi-Hsiang Liu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A

Yoshihito Uchino, Noriyoshi Iriyama, Yoshihiro Hatta, Masami Takei

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Expression of the immune regulation antigen CD70 in osteosarcoma

Jens HW Pahl, Susy J Santos, Marieke L Kuijjer, Gerharda H Boerman, Laurens GL Sand, Karoly Szuhai, Annemarie Cleton-Jansen, R Maarten Egeler, Judith VMG Boveé, Marco W Schilham, Arjan C Lankester

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Combination of cyclophosphamide and double-stranded DNA demonstrates synergistic toxicity against established xenografts

Ekaterina A Alyamkina, Valeriy P Nikolin, Nelly A Popova, Alexandra M Minkevich, Artem V Kozel, Evgenia V Dolgova, Yaroslav R Efremov, Sergey I Bayborodin, Oleg M Andrushkevich, Oleg S Taranov, Vladimir V Omigov, Vladimir A Rogachev, Anastasia S Proskurina, Evgeniy I Vereschagin, Elena V Kiseleva, Maria V Zhukova, Alexandr A Ostanin, Elena R Chernykh, Sergey S Bogachev, Mikhail A Shurdov

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Apigenin, a dietary flavonoid, inhibits proliferation of human bladder cancer T-24 cells via blocking cell cycle progression and inducing apoptosis

Ming-Der Shi, Cheng-Kai Shiao, Yi-Chieh Lee, Yuan-Wei Shih

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Bim and VDAC1 are hierarchically essential for mitochondrial ATF2 mediated cell death

Zhaoyun Liu, Qianfu Luo, Chunbao Guo

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Interferon gamma polymorphisms and hepatitis B virus-related liver cirrhosis risk in a Chinese population

Yifan Sun, Yu Lu, Li Xie, Yan Deng, Shan Li, Xue Qin

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

BCYRN1, a c-MYC-activated long non-coding RNA, regulates cell metastasis of non-small-cell lung cancer

Tao Hu, Yu-Run Lu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

SLPI knockdown induced pancreatic ductal adenocarcinoma cells proliferation and invasion

Wei Zhang, Jian-Long Yao, Shan-Chao Dong, Feng-Qiang Hou, He-Ping Shi

01.12.2015 | Review | Ausgabe 1/2015 Open Access

MicroRNA (miRNA) in cancer

Kaladhar B Reddy

01.12.2015 | Review | Ausgabe 1/2015 Open Access

The role of death-associated protein 3 in apoptosis, anoikis and human cancer

Umar Wazir, Mona MAW Orakzai, Zubair S Khanzada, Wen G Jiang, Anup K Sharma, Abdul Kasem, Kefah Mokbel

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

MicroRNA-378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF

Zhenlei Wang, Bin Ma, Xiaopin Ji, Yang Deng, Tao Zhang, Xiaojian Zhang, Haoji Gao, Hanxing Sun, Haoxuan Wu, Xianze Chen, Ren Zhao

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells

Zhong Zheng, Bingya Liu, Xiaohua Wu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model

Dongmei Chen, Shudan Liu, Huiming Ma, Xueyun Liang, Haibin Ma, Xiurui Yan, Bao Yang, Jun Wei, Xiaoming Liu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Impact of ABCG2 polymorphisms on the clinical outcome of TKIs therapy in Chinese advanced non-small-cell lung cancer patients

Xueqin Chen, Dadong Chen, Shaoyu Yang, Ruobing Ma, Yuelong Pan, Xin Li, Shenglin Ma

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Analyzing the gene expression profile of anaplastic histology Wilms’ tumor with real-time polymerase chain reaction arrays

Jun Lu, Yan-Fang Tao, Zhi-Heng Li, Lan Cao, Shao-Yan Hu, Na-Na Wang, Xiao-Juan Du, Li-Chao Sun, Wen-Li Zhao, Pei-Fang Xiao, Fang Fang, Li-xiao Xu, Yan-Hong Li, Gang Li, He Zhao, Jian Ni, Jian Wang, Xing Feng, Jian Pan

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

Fu-biao Kang, Ling Wang, Heng-chuan Jia, Dong Li, Hai-jun Li, Yin-ge Zhang, Dian-xing Sun

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer

Mohamed Salah I Abaza, Khaled Y Orabi, Ebtehal Al-Quattan, Raja’a J Al-Attiyah

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Multidrug resistance characterization in multicellular tumour spheroids from two human lung cancer cell lines

Raúl Barrera-Rodríguez, Jorge Morales Fuentes

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Expression of long non-coding RNA DLX6-AS1 in lung adenocarcinoma

Juan Li, Ping Li, Wei Zhao, Rui Yang, Shanshan Chen, Yong Bai, Shaozhi Dun, Xiaonan Chen, Yuwen Du, Yuanyuan Wang, Wenqiao Zang, Guoqiang Zhao, Guojun Zhang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

MiR-124 suppresses cell motility and adhesion by targeting talin 1 in prostate cancer cells

Wei Zhang, Ye-qing Mao, Hua Wang, Wen-juan Yin, Shao-xing Zhu, Wei-cheng Wang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

B-cell receptor-guided delivery of peptide-siRNA complex for B-cell lymphoma therapy

Nunzia Migliaccio, Camillo Palmieri, Immacolata Ruggiero, Giuseppe Fiume, Nicola M Martucci, Iris Scala, Ileana Quinto, Giuseppe Scala, Annalisa Lamberti, Paolo Arcari

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells

Muhammad Moazzam, Lin Ye, Ping-Hui Sun, Howard Kynaston, Wen G Jiang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression

HuaPing Li, HuaLi Li, HongJie Qu, MingZhu Zhao, Bo Yuan, MingHua Cao, JinQuan Cui

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Observations on the expression of human papillomavirus major capsid protein in HeLa cells

Chang-Yi Xiao, Bing-Bing Fu, Zhi-Ying Li, Gohar Mushtaq, Mohammad Amjad Kamal, Jia-Hua Li, Gui-Cheng Tang, Shuo-Shuang Xiao

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Inhibitor of caspase-activated DNase expression enhances caspase-activated DNase expression and inhibits oxidative stress-induced chromosome breaks at the mixed lineage leukaemia gene in nasopharyngeal carcinoma cells

Siaw Shi Boon, Sai-Peng Sim

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Up regulation of Bax and down regulation of Bcl2 during 3-NC mediated apoptosis in human cancer cells

Mohammad Hassan Naseri, Majid Mahdavi, Jamshid Davoodi, Saeed Hesami Tackallou, Mahdi Goudarzvand, Shima Hallaj Neishabouri

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

MicroR-545 enhanced radiosensitivity via suppressing Ku70 expression in Lewis lung carcinoma xenograft model

Chen Liao, Wei Xiao, Nuo Zhu, Zhiyuan Liu, Jiu Yang, Yanhu Wang, Mei Hong

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

RB mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells

Mario Orozco-Morales, Francisco Javier Sánchez-García, Irene Golán-Cancela, Norma Hernández-Pedro, Jose A. Costoya, Verónica Pérez de la Cruz, Sergio Moreno-Jiménez, Julio Sotelo, Benjamín Pineda

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

RETRACTED ARTICLE: Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro

Junping Zhang, Linxiang Shao, Chunlin Wu, Hongfei Lu, Ruian Xu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Effect of Matrine on HPAC cell migration by down-regulating the expression of MT1-MMP via Wnt signaling

Yongchao Ma, Fazhang Zou, Junping Xiong, Wei Wan, Li Yin, Xianjia Li, Zhanyu Bei, Lei Yuan, Song Meng, Jianguo Wang, Guohua Song

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Pathological features of transplanted tumor established by CD133 positive TJ905 glioblastoma stem-like cells

Feng Jin, Ran Zhang, Song Feng, Chuan-Tao Yuan, Ren-Ya Zhang, Guang-Kui Han, Gen-Hua Li, Xi-Zhen Yu, Yang Liu, Ling-Sheng Kong, Shu-Ling Zhang, Lei Zhao

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

MicroRNA-24 inhibits growth, induces apoptosis, and reverses radioresistance in laryngeal squamous cell carcinoma by targeting X-linked inhibitor of apoptosis protein

Li Xu, Zhifeng Chen, Fei Xue, Wei Chen, Ruina Ma, Shiyin Cheng, Pengcheng Cui

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Association between underexpression of microrna-203 and clinicopathological significance in hepatocellular carcinoma tissues

Yongru Liu, Fanghui Ren, Minhua Rong, Yihuan Luo, Yiwu Dang, Gang Chen

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Increased expression of Six1 correlates with progression and prognosis of prostate cancer

Jun Zeng, Rong Shi, Cui-xia Cai, Xin-rui Liu, Yan-bin Song, Min Wei, Wen-li Ma

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Only one health, and so many omics

Nives Pećina-Šlaus, Marko Pećina

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells

Chuntuan Li, Pengliang Xin, Huifang Xiao, Yan Zheng, Yuanling Huang, Xiongpeng Zhu

01.12.2015 | Retraction Note | Ausgabe 1/2015 Open Access

Retraction Note: Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro

Junping Zhang, Linxiang Shao, Chunlin Wu, Hongfei Lu, Ruian Xu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Stromal-epithelial responses to fractionated radiotherapy in a breast cancer microenvironment

Muqeem A. Qayyum, Jin Tae Kwak, Michael F. Insana

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

AXIN2 rs2240308 polymorphism contributes to increased cancer risk: evidence based on a meta-analysis

Zhitong Wu, Yifan Sun, Shifu Tang, Chunming Liu, Shengbo Zhu, Lili Wei, Hong Xu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Cyclooxygeanse-2 promotes metastasis in osteosarcoma

Liyan Qu, Bing Liu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

GSK3β mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway

Xu Ying, Li Jing, Shijie Ma, Qianjun Li, Xiaoling Luo, Zhenguo Pan, Yanling Feng, Pan Feng

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

Khalid O Alfarouk, Christian-Martin Stock, Sophie Taylor, Megan Walsh, Abdel Khalig Muddathir, Daniel Verduzco, Adil H H Bashir, Osama Y Mohammed, Gamal O Elhassan, Salvador Harguindey, Stephan J Reshkin, Muntaser E Ibrahim, Cyril Rauch

01.12.2015 | Primary Research | Ausgabe 1/2015 Open Access

Association between IL-18 polymorphisms, serum levels, and HBV-related hepatocellular carcinoma in a Chinese population: a retrospective case–control study

Jingui Bao, Yu Lu, Yan Deng, Chengzhi Rong, Yanqiong Liu, Xiuli Huang, Liuying Song, Shan Li, Xue Qin

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Overexpression of MALT1-A20-NF-κB in adult B-cell acute lymphoblastic leukemia

Yi Xu, Junyan Hu, Xu Wang, Li Xuan, Jing Lai, Ling Xu, Shaohua Chen, Lijian Yang, Gengxin Luo, Kanger Zhu, Xiuli Wu, Yangqiu Li

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

RETRACTED ARTICLE: Mechanistic attributes of S100A7 (psoriasin) in resistance of anoikis resulting tumor progression in squamous cell carcinoma of the oral cavity

Kaushik Kumar Dey, Siddik Sarkar, Ipsita Pal, Subhasis Das, Goutam Dey, Rashmi Bharti, Payel Banik, Joygopal Roy, Sukumar Maity, Indranil kulavi, Mahitosh Mandal

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells

Thomas Metterlein, Petra Hoffmann, Ruth Späth, Michael Gruber, Bernhard M Graf, Wolfgang Zink

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma

Ali Rihani, Jo Vandesompele, Frank Speleman, Tom Van Maerken

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Antisense oligonucleotides against microRNA-21 reduced the proliferation and migration of human colon carcinoma cells

Yi-Jing Tao, Yong-ju Li, Wen Zheng, Juan-juan Zhao, Meng-meng Guo, Ya Zhou, Na-lin Qin, Jing Zheng, Lin Xu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells

Jun Ma, Jun Liu, Chunwei Lu, Dingfang Cai

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Etoposide induces cell death via mitochondrial-dependent actions of p53

Sarwat Jamil, Irene Lam, Maryam Majd, Shu-Huei Tsai, Vincent Duronio

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Expression and clinicopathological significance of miR-193a-3p and its potential target astrocyte elevated gene-1 in non-small lung cancer tissues

Fanghui Ren, Hua Ding, Suning Huang, Hanlin Wang, Mei Wu, Dianzhong Luo, Yiwu Dang, Lihua Yang, Gang Chen

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Effects of the aqueous extract of a Tibetan herb, Rhodiola algida var. tangutica on proliferation and HIF-1α, HIF-2α expression in MCF-7 cells under hypoxic condition in vitro

Yu-juan Qi, Sen Cui, Dian-xiang Lu, Ying-zhong Yang, Yushuang Luo, Lan Ma, Yan Ma, Tana Wuren, Rong Chang, Lei Qi, Ba-ji Ben, Jun Han, Ri-Li Ge

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Antitumoral potency of methanolic extract from Nitraria retusa leaves via its immunomodulatory effect

Jihed Boubaker, Fadwa Chaabane, Ahmed Bedoui, Rihab Aloui, Besma Ben Ahmed, Kamel Ghedira, Leila Chekir-Ghedira

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

STAT3 activation is required for the antiapoptotic effects of prolactin in cervical cancer cells

Adrián Ramírez de Arellano, Edgar I. Lopez-Pulido, Priscila A. Martínez-Neri, Ciro Estrada Chávez, Renee González Lucano, Mary Fafutis-Morris, A. Aguilar-Lemarroy, José. F. Muñoz-Valle, Ana Laura Pereira-Suárez

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

MicroRNA-125b promotes tumor metastasis through targeting tumor protein 53-induced nuclear protein 1 in patients with non-small-cell lung cancer

Qinchuan Li, Yang Han, Chunhong Wang, Shan Shan, Yuanyuan Wang, Jingang Zhang, Tao Ren

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

microRNA-30b inhibits cell invasion and migration through targeting collagen triple helix repeat containing 1 in non-small cell lung cancer

Shanshan Chen, Ping Li, Rui Yang, Ruirui Cheng, Furui Zhang, Yuanyuan Wang, Xiaonan Chen, Qianqian Sun, Wenqiao Zang, Yuwen Du, Guoqiang Zhao, Guojun Zhang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

RETRACTED ARTICLE: Down-regulation of miR-133a and miR-539 are associated with unfavorable prognosis in patients suffering from osteosarcoma

Alireza Mirghasemi, Afshin Taheriazam, Seyyed Hasan Karbasy, Ali Torkaman, Mohammadreza Shakeri, Emad Yahaghi, Aram Mokarizadeh

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Dysregulated miR-645 affects the proliferation and invasion of head and neck cancer cell

Qiang Sun, Shuai Chen, Xue Zhao, Ming Yan, Zheng Fang, Haibin Wang, Junfang Zhao, Minglei Sun, Xinguang Han, Wantao Chen, Xinming Li

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial–mesenchymal cooperative interaction

Alicia A. Goyeneche, Michael Koch, Maria C. Bell, Carlos M. Telleria

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Cyclin D3 predicts disease-free survival in breast cancer

Yayun Chi, Sheng Huang, Mengying Liu, Liang Guo, Xuxia Shen, Jiong Wu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Jacaric acid inhibits the growth of murine macrophage-like leukemia PU5-1.8 cells by inducing cell cycle arrest and apoptosis

Wai Nam Liu, Kwok Nam Leung

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

PDK1-mTOR signaling pathway inhibitors reduce cell proliferation in MK2206 resistant neuroblastoma cells

Lei Qi, Hidemi Toyoda, Dong-qing Xu, Ye Zhou, Naoto Sakurai, Keishirou Amano, Kentaro Kihira, Hiroki Hori, Eiichi Azuma, Yoshihiro Komada

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Implications of miR cluster 143/145 as universal anti-oncomiRs and their dysregulation during tumorigenesis

Ani V. Das, Radhakrishna M. Pillai

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia

Xin Huang, Suxia Geng, Jianyu Weng, Zesheng Lu, Lingji Zeng, Minming Li, Chengxin Deng, Xiuli Wu, Yangqiu Li, Xin Du

01.12.2015 | Erratum | Ausgabe 1/2015 Open Access

Erratum to: Mechanistic attributes of S100A7 (psoriasin) in resistance of anoikis resulting tumor progression in squamous cell carcinoma of the oral cavity

Kaushik Kumar Dey, Siddik Sarkar, Ipsita Pal, Subhasis Das, Goutam Dey, Rashmi Bharti, Payel Banik, Jay Gopal Ray, Sukumar Maity, Indranil kulavi, Mahitosh Mandal

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Ideal sphere-forming culture conditions to maintain pluripotency in a hepatocellular carcinoma cell lines

Seon Ok Min, Sang Woo Lee, Seon Young Bak, Kyung Sik Kim

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy

Thamil Selvee Ramasamy, Ain Zubaidah Ayob, Hsu Hsu Lynn Myint, Sharmanee Thiagarajah, Farahnaz Amini

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Induction of atypical cell death in thyroid carcinoma cells by the indirubin derivative 7-bromoindirubin-3′-oxime (7BIO)

Martina Broecker-Preuss, Nina Becher-Boveleth, Susanne Gall, Katrin Rehmann, Susann Schenke, Klaus Mann

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cells

Chih-Cheng Chen, Kuan-Der Lee, Mei-Yu Pai, Pei-Yi Chu, Chia-Chen Hsu, Chia-Chen Chiu, Li-Tzong Chen, Jang-Yang Chang, Shu-Huei Hsiao, Yu-Wei Leu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The pluripotency factor LIN28B is involved in oral carcinogenesis and associates with tumor aggressiveness and unfavorable prognosis

Dongmiao Wang, Yuming Zhu, Yanling Wang, Zhongwu Li, Chunping Yuan, Wei Zhang, Hua Yuan, Jinhai Ye, Jianrong Yang, Hongbing Jiang, Jie Cheng

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Xanthorrhizol: a review of its pharmacological activities and anticancer properties

Seok Fang Oon, Meenakshii Nallappan, Thiam Tsui Tee, Shamarina Shohaimi, Nur Kartinee Kassim, Mohd Shazrul Fazry Sa’ariwijaya, Yew Hoong Cheah

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer

Min Sha, Jun Ye, Zheng-yun Luan, Ting Guo, Bian Wang, Jun-xing Huang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The choroid plexus may be an underestimated site of tumor invasion to the brain: an in vitro study using neuroblastoma cell lines

Elodie Vandenhaute, Carolin Stump-Guthier, María Lasierra Losada, Tobias Tenenbaum, Henriette Rudolph, Hiroshi Ishikawa, Christian Schwerk, Horst Schroten, Matthias Dürken, Martin März, Michael Karremann

01.12.2015 | Review | Ausgabe 1/2015 Open Access

MicroRNA-7: a promising new target in cancer therapy

Juanjuan Zhao, Yijing Tao, Ya Zhou, Nalin Qin, Chao Chen, Dan Tian, Lin Xu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Dimethylsulfoxide excerbates cisplatin-induced cytotoxicity in Ehrlich ascites carcinoma cells

Abdel-Moneim M. Osman, Ali A. Alqahtani, Zoheir A. Damanhouri, Sameer E. Al-Harthy, Mohamed F. ElShal, Wafaa S. Ramadan, Fatemah Kamel, Mohamed A. M. Osman, Lateef M. Khan

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Time depended Bcl-2 inhibition might be useful for a targeted drug therapy

Abdolhassan Talaiezadeh, Fateme jalali, Hamid Galehdari, Ali Khodadadi

01.12.2015 | Review Article | Ausgabe 1/2015 Open Access

Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

Bing Liu, Liyan Qu, Shigui Yan

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Upregulation of microRNA-96 and its oncogenic functions by targeting CDKN1A in bladder cancer

Ziyu Wu, Kun Liu, Yunyan Wang, Zongyuan Xu, Junsong Meng, Shuo Gu

01.12.2015 | Erratum | Ausgabe 1/2015 Open Access

Erratum to: PDK1-mTOR signaling pathway inhibitors reduce cell proliferation in MK2206 resistant neuroblastoma cells

Lei Qi, Hidemi Toyoda, Dong-qing Xu, Ye Zhou, Naoto Sakurai, Keishirou Amano, Kentaro Kihira, Hiroki Hori, Eiichi Azuma, Yoshihiro Komada

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Eukaryotic translation initiation factor 5A2 (eIF5A2) regulates chemoresistance in colorectal cancer through epithelial mesenchymal transition

Ying Bao, Yongliang Lu, Xiang Wang, Wenming Feng, Xinrong Sun, Huihui Guo, Chengwu Tang, Xiaojing Zhang, Qilin Shi, Hongbin Yu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Morphological and molecular characterization of the human breast epithelial cell line M13SV1 and its tumorigenic derivatives M13SV1-R2-2 and M13SV1-R2-N1

Sandra Stempin, Anika Engel, Nora Winkler, Thorsten Buhrke, Alfonso Lampen

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

STAT1 inhibits human hepatocellular carcinoma cell growth through induction of p53 and Fbxw7

Jiayu Chen, Haihe Wang, Jing Wang, Shishun Huang, Wei Zhang

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation

Danielle L. Bourgeois, Karl A. Kabarowski, Veronica L. Porubsky, Pamela K. Kreeger

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Clinical relevance of thyroid cell models in redox research

Francesca Cammarota, Francesco Fiscardi, Tiziana Esposito, Gabriella de Vita, Marco Salvatore, Mikko O. Laukkanen

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

ESC reverses epithelial mesenchymal transition induced by transforming growth factor-β via inhibition of Smad signal pathway in HepG2 liver cancer cells

Xiao-Ni Liu, Shuang Wang, Qing Yang, Ya-Jie Wang, De-Xi Chen, Xiao-Xin Zhu

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Bioinformatics identification of potentially involved microRNAs in Tibetan with gastric cancer based on microRNA profiling

Yushuang Luo, Chengwu Zhang, Feng Tang, Junhui Zhao, Cunfang Shen, Cheng Wang, Pengjie Yu, Miaozhou Wang, Yan Li, J. I. Di, Rong Chen, Ge Rili

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms

Guifang Yu, Xuezhu Chen, Shudi Chen, Weipeng Ye, Kailian Hou, Min Liang

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Potential targets for ovarian clear cell carcinoma: a review of updates and future perspectives

Shinya Matsuzaki, Kiyoshi Yoshino, Yutaka Ueda, Satoko Matsuzaki, Mamoru Kakuda, Akiko Okazawa, Tomomi Egawa-Takata, Eiji Kobayashi, Tadashi Kimura

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Reduced IL-33 plasma levels in aplastic anemia

Ming Sun, Hai-feng Ma, Ye-yun Che, Xin Cui

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1)

Eszter Lajkó, Péter Bányai, Zsófia Zámbó, László Kursinszki, Éva Szőke, László Kőhidai

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Upregulated expression of DIXDC1 in intestinal-type gastric carcinoma: co-localization with β-catenin and correlation with poor prognosis

Lei Wang, Cong Tan, Fan Qiao, Weige Wang, Xiangnan Jiang, Peng Lian, Bin Chang, Weiqi Sheng

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

The effects of MOTILIPERM on cisplatin induced testicular toxicity in Sprague–Dawley rats

Kiran Kumar Soni, Li Tao Zhang, Jae Hyung You, Sung Won Lee, Chul Young Kim, Wan Shou Cui, Han Jung Chae, Hye Kyung Kim, Jong Kwan Park

01.12.2015 | Primary research | Ausgabe 1/2015 Open Access

Treatment with G-CSF reduces acute myeloid leukemia blast viability in the presence of bone marrow stroma

Meritxell Nomdedeu, María Carmen Lara-Castillo, Amaia Etxabe, Josep María Cornet-Masana, Marta Pratcorona, Marina Díaz-Beyá, Xavier Calvo, María Rozman, Dolors Costa, Jordi Esteve, Ruth M. Risueño

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