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Zeitschrift

Cancer Cell International

Cancer Cell International 1/2018

Ausgabe 1/2018

Inhaltsverzeichnis ( 219 Artikel )

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Prognostic and clinicopathological significance of long noncoding RNA HOXA11-AS expression in human solid tumors: a meta-analysis

Shidai Mu, Lisha Ai, Fengjuan Fan, Chunyan Sun, Yu Hu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MicroRNA 200c-3p regulates autophagy via upregulation of endoplasmic reticulum stress in PC-3 cells

Eun Jung Sohn

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Collapsin response mediator protein 4 promotor methylation level as a potential predictor for diagnosing primary malignant lymphoma of the prostate

Zheng Chen, Qiong Liang, Jue Wang, Qun-Xiong Huang, Jian-ning Chen, Zi-jin Weng, Chun-kui Shao, Xin Gao, Jun Pang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line

Jin Li, Yuan Wang, Cheng-Gong Zhang, Hai-Juan Xiao, Jun-Ming Hou, Jing-Dong He

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MiR-20a-5p suppresses tumor proliferation by targeting autophagy-related gene 7 in neuroblastoma

Yongbo Yu, Jie Zhang, Yaqiong Jin, Yeran Yang, Jin Shi, Feng Chen, Shujing Han, Ping Chu, Jie Lu, Huanmin Wang, Yongli Guo, Xin Ni

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma

Yang Zheng, Zhao Wang, Xu Ding, Wei Zhang, Gang Li, Laikui Liu, Heming Wu, Wenyi Gu, Yunong Wu, Xiaomeng Song

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer: our experience in thyroid surgery

Alessio Metere, Francesca Frezzotti, Claire Elizabeth Graves, Massimo Vergine, Alessandro De Luca, Donatella Pietraforte, Laura Giacomelli

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

SHP-2 restricts apoptosis induced by chemotherapeutic agents via Parkin-dependent autophagy in cervical cancer

Dewen Yan, Danyang Zhu, Xiumin Zhao, Jun Su

01.12.2018 | Hypothesis | Ausgabe 1/2018 Open Access

Xenogeneic cell therapy provides a novel potential therapeutic option for cancers by restoring tissue function, repairing cancer wound and reviving anti-tumor immune responses

Chi-Ping Huang, Chi-Cheng Chen, Chih-Rong Shyr

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MicroRNA-10b regulates epithelial–mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma

Gulibaha Hujie, Sheng-hua Zhou, Hua Zhang, Jie Qu, Xiao-wei Xiong, Outikuer Hujie, Cheng-gong Liao, Shun-e Yang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Exosomal lncRNA 91H is associated with poor development in colorectal cancer by modifying HNRNPK expression

Tianyi Gao, Xiangxiang Liu, Bangshun He, Zhenlin Nie, Chengbin Zhu, Pei Zhang, Shukui Wang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells

Liangqian Jiang, Yujuan Wang, Guoxiang Liu, Huihui Liu, Feng Zhu, Huanhuan Ji, Bing Li

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Down regulation of G protein-coupled receptor 137 expression inhibits proliferation and promotes apoptosis in leukemia cells

Li-Jie Men, Ji-Zhu Liu, Hai-Ying Chen, Li Zhang, Shuang-Feng Chen, Tai-Wu Xiao, Jing-Xia Wang, Guang-Yao Li, Ya-Ping Wu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Different TP53 mutants in p53 overexpressed epithelial ovarian carcinoma can be associated both with altered and unaltered glycolytic and apoptotic profiles

Stephanie Antoun, David Atallah, Roula Tahtouh, Nada Alaaeddine, Malak Moubarak, Abir Khaddage, Eliane Nasr Ayoub, George Chahine, George Hilal

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Imiquimod inhibits growth and induces differentiation of myeloid leukemia cell lines

Eva Villamón, Javier González-Fernández, Esperanza Such, José Vicente Cervera, Daniel Gozalbo, M. Luisa Gil

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MiR-539 inhibits proliferation and migration of triple-negative breast cancer cells by down-regulating LAMA4 expression

Zhi-Xue Yang, Bo Zhang, Jinrong Wei, Guo-Qin Jiang, Yan-Lin Wu, Bing-Jing Leng, Chun-Gen Xing

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line

Jin Li, Yuan Wang, Cheng-Gong Zhang, Han-Juan Xiao, Jun-Ming Hu, Jing-Dong He

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression

Renato F. Ivanovic, Nayara I. Viana, Denis R. Morais, Iran A. Silva, Katia R. Leite, José Pontes-Junior, Gustavo Inoue, William C. Nahas, Miguel Srougi, Sabrina T. Reis

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Cumulative receiver operating characteristics for analyzing interaction between tissue visfatin and clinicopathologic factors in breast cancer progression

Sin-Hua Moi, Yi-Chen Lee, Li-Yeh Chuang, Shyng-Shiou F. Yuan, Fu Ou-Yang, Ming-Feng Hou, Cheng-Hong Yang, Hsueh-Wei Chang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

RRS1 gene expression involved in the progression of papillary thyroid carcinoma

Feng Chen, Yaqiong Jin, Lin Feng, Jie Zhang, Jun Tai, Jin Shi, Yongbo Yu, Jie Lu, Shengcai Wang, Xin Li, Ping Chu, Shujing Han, Shujun Cheng, Yongli Guo, Xin Ni

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Whole exome sequencing reveals novel somatic alterations in neuroblastoma patients with chemotherapy

Chao Duan, Han Wang, Ying Chen, Ping Chu, Tianyu Xing, Chao Gao, Zhixia Yue, Jie Zheng, Mei Jin, Weiyue Gu, Xiaoli Ma

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Loss of PIM1 correlates with progression and prognosis of salivary adenoid cystic carcinoma (SACC)

Jiajie Xu, Xin Zhu, Qingling Li, Chao Chen, Zhenying Guo, Zhuo Tan, Chuanming Zheng, Minghua Ge

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Depletion of membrane cholesterol compromised caspase-8 imparts in autophagy induction and inhibition of cell migration in cancer cells

Mukesh Kumar, Karuna Irungbam, Meena Kataria

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Catalase down-regulation in cancer cells exposed to arsenic trioxide is involved in their increased sensitivity to a pro-oxidant treatment

Christophe Glorieux, Pedro Buc Calderon

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Increased ETV4 expression correlates with estrogen-enhanced proliferation and invasiveness of cholangiocarcinoma cells

Ekapot Singsuksawat, Chanitra Thuwajit, Komgrid Charngkaew, Peti Thuwajit

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MLL2/KMT2D and MLL3/KMT2C expression correlates with disease progression and response to imatinib mesylate in chronic myeloid leukemia

Doralina do Amaral Rabello, Vivian D’Afonseca da Silva Ferreira, Maria Gabriela Berzoti-Coelho, Sandra Mara Burin, Cíntia Leticia Magro, Maira da Costa Cacemiro, Belinda Pinto Simões, Felipe Saldanha-Araujo, Fabíola Attié de Castro, Fabio Pittella-Silva

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Integrated TCGA analysis implicates lncRNA CTB-193M12.5 as a prognostic factor in lung adenocarcinoma

Xuehai Wang, Gang Li, Qingsong Luo, Jiayong Xie, Chongzhi Gan

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Unique CD44 intronic SNP is associated with tumor grade in breast cancer: a case control study and in silico analysis

Rezvan Esmaeili, Nasrin Abdoli, Fatemeh Yadegari, Mohamadreza Neishaboury, Leila Farahmand, Ahmad Kaviani, Keivan Majidzadeh-A

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

The tyrosine kinase inhibitor nilotinib is more efficient than mitotane in decreasing cell viability in spheroids prepared from adrenocortical carcinoma cells

Elaine Silveira, Isadora Pontes Cavalcante, Jean Lucas Kremer, Pedro Omori Ribeiro de Mendonça, Claudimara Ferini Pacicco Lotfi

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Arachidonic acid-induced Ca2+ entry and migration in a neuroendocrine cancer cell line

Priyodarshan Goswamee, Tamar Pounardjian, David R. Giovannucci

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma

Yongchang Lai, Zhijian Zhao, Tao Zeng, Xiongfa Liang, Dong Chen, Xiaolu Duan, Guohua Zeng, Wenqi Wu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Epidermal growth factor-mediated Rab25 pathway regulates integrin β1 trafficking in colon cancer

Kyung Sook Hong, Eun-Young Jeon, Soon Sup Chung, Kwang Ho Kim, Ryung-Ah Lee

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance

Andrea Vazanova, Jana Jurecekova, Tomas Balharek, Juraj Marcinek, Jan Stasko, Anton Dzian, Lukas Plank, Pavol Zubor, Peter Racay, Jozef Hatok

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Prognostic role of long non-coding RNA XIST expression in patients with solid tumors: a meta-analysis

Huihui Mao, Kai Wang, Yuehua Feng, Jun Zhang, Lili Pan, Yuxia Zhan, Haijun Sheng, Guanghua Luo

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Overexpression of Rab11-FIP2 in colorectal cancer cells promotes tumor migration and angiogenesis through increasing secretion of PAI-1

Wenjie Dong, Xinai Wu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting FBPase is an emerging novel approach for cancer therapy

Gao-Min Liu, Yao-Ming Zhang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

The long non-coding RNA AK001796 contributes to tumor growth via regulating expression of p53 in esophageal squamous cell carcinoma

Bin Liu, Chun-Feng Pan, Guo-Liang Yao, Ke Wei, Yang Xia, Yi-Jiang Chen

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Downregulation of microRNA-21 inhibited radiation-resistance of esophageal squamous cell carcinoma

Fang Li, Jia-Hua Lv, Long Liang, Jun-chao Wang, Chu-Rong Li, Lei Sun, Tao Li

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia

Fei-Fei Liu, Kai-Ling Wang, Li-Ping Deng, Xiao Liu, Min-yuan Wu, Tian-You Wang, Lei Cui, Zhi-Gang Li

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

Ran Xu, Xuan Zhu, Fangzhi Chen, Changkun Huang, Kai Ai, Hongtao Wu, Lei Zhang, Xiaokun Zhao

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

Dehui Xu, Yujing Xu, Ning Ning, Qingjie Cui, Zhijie Liu, Xiaohua Wang, Dingxin Liu, Hailan Chen, Michael G. Kong

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D

Michael F. Sweeney, Carlos Sonnenschein, Ana M. Soto

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Resistance a major hindrance to chemotherapy in hepatocellular carcinoma: an insight

K. Lohitesh, Rajdeep Chowdhury, Sudeshna Mukherjee

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Long noncoding RNA LINC01510 promotes the growth of colorectal cancer cells by modulating MET expression

Chaoqun Cen, Jian Li, Jingjing Liu, Mingshi Yang, Tianyi Zhang, Yu Zuo, Changwei Lin, Xiaorong Li

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Epistructured catechins, EGCG and EC facilitate apoptosis induction through targeting de novo lipogenesis pathway in HepG2 cells

Phuriwat Khiewkamrop, Pattamaphron Phunsomboon, Lysiane Richert, Dumrongsak Pekthong, Piyarat Srisawang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Prognostic value of long non-coding RNA BLACAT1 in patients with papillary thyroid carcinoma

Denghui Liao, Gang Lv, Ting Wang, Jie Min, Yadong Wang, Shengchun Liu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Effects of secreted frizzled-related protein 1 on proliferation, migration, invasion, and apoptosis of colorectal cancer cells

Zhongchuan Wang, Rujia Li, Yongshan He, Shiyong Huang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

microRNA-338-3p inhibits proliferation, migration, invasion, and EMT in osteosarcoma cells by targeting activator of 90 kDa heat shock protein ATPase homolog 1

Riliang Cao, Jianli Shao, Yabin Hu, Liang Wang, Zhizhong Li, Guodong Sun, Xiaoliang Gao

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

A cross-talk between integrin β4 and epidermal growth factor receptor induces gefitinib chemoresistance to gastric cancer

Jia Huafeng, Zhang Deqing, Ding Yong, Zhang Yulian, Hu Ailing

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Tumor-suppressor role of miR-139-5p in endometrial cancer

JinHui Liu, ChunYu Li, Yi Jiang, YiCong Wan, ShuLin Zhou, WenJun Cheng

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer

Chenwei Pan, Luxia Xiang, Zhenzhen Pan, Xiaodong Wang, Jie Li, Lu Zhuge, Peipei Fang, Qipeng Xie, Xuezhen Hu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells

Chao Zhou, Jie Ma, Mengyuan Su, Dan Shao, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Yan Meng, Ping Jiao

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MiR-144-3p promotes the tumor growth and metastasis of papillary thyroid carcinoma by targeting paired box gene 8

Chang Liu, Chang Su, Yanchun Chen, Guang Li

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: MicroRNA-214-3p inhibits proliferation and cell cycle progression by targeting MELK in hepatocellular carcinoma and correlates cancer prognosis

Yue Li, You Li, Yao Chen, Qian Xie, Ningning Dong, Yanjun Gao, Huan Deng, Chunhua Lu, Suihai Wang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition

Jianbo Zheng, Yanhui Mei, Ping Xiang, Guangsheng Zhai, Ning Zhao, Chuanbing Xu, Min Liu, Zhengsheng Pan, Kai Tang, Dongsheng Jia

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Epithelial to mesenchymal transition induces stem cell like phenotype in renal cell carcinoma cells

Mamta Singla, Ajay Kumar, Amanjit Bal, Subhendu Sarkar, Shalmoli Bhattacharyya

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Targeted delivery of immuno-RNase may improve cancer therapy

Miaonan Sun, Liankun Sun, Dejun Sun, Chunmei Zhang, Mei Li

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Long non-coding RNA MIAT promotes growth and metastasis of colorectal cancer cells through regulation of miR-132/Derlin-1 pathway

Zhaoxia Liu, Hai Wang, Hongwei Cai, Ye Hong, Yan Li, Dongming Su, Zhining Fan

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Identification of four differentially methylated genes as prognostic signatures for stage I lung adenocarcinoma

Wei-Ming Luo, Zheng-Yu Wang, Xin Zhang

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Prognostic role of RDW in hematological malignancies: a systematic review and meta-analysis

Lisha Ai, Shidai Mu, Yu Hu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Allogeneic stem-cell transplantation for multiple myeloma: a systematic review and meta-analysis from 2007 to 2017

Xuejiao Yin, Liang Tang, Fengjuan Fan, Qinyue Jiang, Chunyan Sun, Yu Hu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors

Sanja Aveic, Marcella Pantile, Pierfrancesco Polo, Viktoryia Sidarovich, Marilena De Mariano, Alessandro Quattrone, Luca Longo, Gian Paolo Tonini

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MicroRNA-365 promotes lung carcinogenesis by downregulating the USP33/SLIT2/ROBO1 signalling pathway

Yuhuan Wang, Shuhua Zhang, Hejing Bao, Shukun Mu, Baishen Zhang, Hao Ma, Shudong Ma

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

Karen K. L. Chan, Michelle K. Y. Siu, Yu-xin Jiang, Jing-jing Wang, Thomas H. Y. Leung, Hextan Y. S. Ngan

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

miR-1236-3p inhibits invasion and metastasis in gastric cancer by targeting MTA2

Jia-Xiang An, Ming-Hui Ma, Chun-Dong Zhang, Shuai Shao, Nuo-Ming Zhou, Dong-Qiu Dai

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Analysis of the role of rs2031920 and rs3813867 polymorphisms within the cytochrome P450 2E1 gene in the risk of squamous cell carcinoma

Hai Zhang, Haiyan Li, Huanxin Yu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Prognostic significance of CXCL5 expression in cancer patients: a meta-analysis

Binwu Hu, Huiqian Fan, Xiao Lv, Songfeng Chen, Zengwu Shao

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

Bodo Haas, Veronika Klinger, Christina Keksel, Verena Bonigut, Daniela Kiefer, Julia Caspers, Julia Walther, Maria Wos-Maganga, Sandra Weickhardt, Gabriele Röhn, Marco Timmer, Roland Frötschl, Niels Eckstein

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

LncRNA PVT1 promotes the growth of HPV positive and negative cervical squamous cell carcinoma by inhibiting TGF-β1

Xiuli Wang, Guichan Wang, Lijuan Zhang, Jianglin Cong, Jianqing Hou, Chunyan Liu

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models

Sergio Regufe da Mota, Sarah Bailey, Rosemary A. Strivens, Annette L. Hayden, Leon R. Douglas, Patrick J. Duriez, M. Teresa Borrello, Hanae Benelkebir, A. Ganesan, Graham Packham, Simon J. Crabb

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

miR-93-5p enhance lacrimal gland adenoid cystic carcinoma cell tumorigenesis by targeting BRMS1L

Jie Hao, Xin Jin, Yan Shi, Hong Zhang

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: CBFA2T2 is associated with a cancer stem cell state in renal cell carcinoma

Du-Chu Chen, You-De Liang, Liang Peng, Yi-Ze Wang, Chun-Zhi Ai, Xin-Xing Zhu, Ya-Wei Yan, Yasmeen Saeed, Bin Yu, Jingying Huang, Yuxin Gao, Jiaqi Liu, Yi-Zhou Jiang, Min Liu, Demeng Chen

01.12.2018 | Primary Research | Ausgabe 1/2018 Open Access

Up-regulation of CTD-2547G23.4 in hepatocellular carcinoma tissues and its prospective molecular regulatory mechanism: a novel qRT-PCR and bioinformatics analysis study

Dong-yue Wen, Peng Lin, Hai-wei Liang, Xia Yang, Hai-yuan Li, Yun He, Hong Yang, Gang Chen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The role of bile acids in cellular invasiveness of gastric cancer

Yu-Chung Wu, Chang-Fang Chiu, Chung-Tzu Hsueh, Chung-Tsen Hsueh

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Overexpression of long non-coding RNA SOX2OT promotes esophageal squamous cell carcinoma growth

Yuanyuan Wu, Xuedan Chen, Yan Liang, Juan Li, Kun Zhang, Limeng Dai, Xingying Guan, Kai Wang, Yun Bai

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

In situ characterization of stem cells-like biomarkers in meningiomas

Hanin Alamir, Mona Alomari, Abdulla Ahmed A. Salwati, Mohamad Saka, Mohammed Bangash, Saleh Baeesa, Fahad Alghamdi, Angel Carracedo, Hans-Juergen Schulten, Adeel Chaudhary, Adel Abuzenadah, Deema Hussein

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

APOBEC3B up-regulation independently predicts ovarian cancer prognosis: a cohort study

Yan Du, Xiang Tao, Jing Wu, Huandi Yu, Yinhua Yu, Hongbo Zhao

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins

Banghua Zhong, Kewei Wang, Hao Xu, Fanmin Kong

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147

Li Li, Xiaoxia Dong, Feng Peng, Li Shen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The expression of protease-activated receptors in esophageal carcinoma cells: the relationship between changes in gene expression and cell proliferation, apoptosis in vitro and growing ability in vivo

Ping Jiang, Shu De Li, Zhi Gang Li, Yue Chun Zhu, Xiao Jia Yi, Si Man Li

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma

Katie L. Uhl, Chad R. Schultz, Dirk Geerts, André S. Bachmann

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF

Weijian Lun, Xiongjian Wu, Qiliang Deng, Fachao Zhi

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Interferon-γ and Smac mimetics synergize to induce apoptosis of lung cancer cells in a TNFα-independent manner

Qin Hao, Hua Tang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting dendritic cells in pancreatic ductal adenocarcinoma

Anton Deicher, Roland Andersson, Bobby Tingstedt, Gert Lindell, Monika Bauden, Daniel Ansari

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

ETS1 is associated with cisplatin resistance through IKKα/NF-κB pathway in cell line MDA-MB-231

Yuzhu Zhang, Jingjing Wu, Meina Ye, Bing Wang, Jiayu Sheng, Bailing Shi, Hongfeng Chen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer

Jian-Bing Xiao, Xin-Lei Li, Le Liu, Geng Wang, Song-Nan Hao, Hui-Juan Dong, Xue-Min Wang, Ya-Fang Zhang, Hui-Dong Liu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The nuclear transcription factor RelB functions as an oncogene in human lung adenocarcinoma SPC-A1 cells

Hualong Qin, Jun Zhou, Jingjing Xu, Li Cheng, Zaixiang Tang, Haitao Ma, Feng Guo

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

miR-133a function in the pathogenesis of dedifferentiated liposarcoma

Peter Y. Yu, Gonzalo Lopez, Danielle Braggio, David Koller, Kate Lynn J. Bill, Bethany C. Prudner, Abbie Zewdu, James L. Chen, O. Hans Iwenofu, Dina Lev, Anne M. Strohecker, Joelle M. Fenger, Raphael E. Pollock, Denis C. Guttridge

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways

Ya-Jun Zhang, Zhi-Gang Xu, Shi-Qiang Li, Liu-Jun He, Yan Tang, Zhong-Zhu Chen, Dong-Lin Yang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

Juan Li, Hang Li, Xiaoting Lv, Zitai Yang, Min Gao, Yanhong Bi, Ziwei Zhang, Shengli Wang, Zhigang Cui, Baosen Zhou, Zhihua Yin

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

rs61991156 in miR-379 is associated with low capability of glycolysis of gastric cancer by enhanced regulation of PKM2

Na Cao, Meng Li, Jun Han, Yongren Wang, Xiaowei Wang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer

Jessica Iorio, Icro Meattini, Simonetta Bianchi, Marco Bernini, Virginia Maragna, Luca Dominici, Donato Casella, Vania Vezzosi, Lorenzo Orzalesi, Jacopo Nori, Lorenzo Livi, Annarosa Arcangeli, Elena Lastraioli

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

TROP2 methylation and expression in tamoxifen-resistant breast cancer

Stephanie M. Zimmers, Eva P. Browne, Kristin E. Williams, Rahul M. Jawale, Christopher N. Otis, Sallie S. Schneider, Kathleen F. Arcaro

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MiR-98 modulates macrophage polarization and suppresses the effects of tumor-associated macrophages on promoting invasion and epithelial–mesenchymal transition of hepatocellular carcinoma

Lei Li, Pengfei Sun, Chengsheng Zhang, Zongchao Li, Kai Cui, Wuyuan Zhou

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells

Xiao-Fang Wei, You-Fan Feng, Qiao-Lin Chen, Qi-Ke Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway

Haiqun Chen, Gang Dai, Yiting Cai, Qinhao Gong, Wei Wu, Min Gao, Zhewei Fei

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2

Jianping Guo, Chong Hao, Congcong Wang, Luo Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Molecular biomarkers in gastro-esophageal cancer: recent developments, current trends and future directions

Francesca Battaglin, Madiha Naseem, Alberto Puccini, Heinz-Josef Lenz

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

B7-H4 overexpression contributes to poor prognosis and drug-resistance in triple-negative breast cancer

Ling Wang, Chao Yang, Xin-bo Liu, Li Wang, Fu-biao Kang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Nanostructured lipid carriers for MicroRNA delivery in tumor gene therapy

Hairong Wang, Shiming Liu, Li Jia, Fengyun Chu, Ya Zhou, Zhixu He, Mengmeng Guo, Chao Chen, Lin Xu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The anticancer effects of ferulic acid is associated with induction of cell cycle arrest and autophagy in cervical cancer cells

Jinhua Gao, Hui Yu, Weikang Guo, Ying Kong, lina Gu, Qi Li, Shanshan Yang, Yunyan Zhang, Yaoxian Wang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Identification of long non-coding RNA signatures in triple-negative breast cancer

Tian Tian, Zhouqing Gong, Meng Wang, Ruohan Hao, Shuai Lin, Kang Liu, Feng Guan, Peng Xu, Yujiao Deng, Dingli Song, Na Li, Ying Wu, Zhijun Dai

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Activated gastric cancer-associated fibroblasts contribute to the malignant phenotype and 5-FU resistance via paracrine action in gastric cancer

Yongchen Ma, Jing Zhu, Shanwen Chen, Tengyu Li, Ju Ma, Shihao Guo, Jianwen Hu, Taohua Yue, Junling Zhang, Pengyuan Wang, Xin Wang, Guowei Chen, Yucun Liu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

miR-145 and miR-497 suppress TGF-β-induced epithelial–mesenchymal transition of non-small cell lung cancer by targeting MTDH

Qi Yin, Yang Han, Dongyi Zhu, Zhanxia Li, Shan Shan, Wenjing Jin, Qingchun Lu, Tao Ren

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The prognostic potential of coilin in association with p27 expression in pediatric acute lymphoblastic leukemia for disease relapse

Zhi-Xia Yue, Rui-qi Gao, Chao Gao, Shu-Guang Liu, Xiao-Xi Zhao, Tian-Yu Xing, Jing Niu, Zhi-Gang Li, Hu-Yong Zheng, Wei Ding

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Expression profile analysis of antisense long non-coding RNA identifies WDFY3-AS2 as a prognostic biomarker in diffuse glioma

Fan Wu, Zheng Zhao, Ruichao Chai, Yuqing Liu, Kuanyu Wang, Zhiliang Wang, Guanzhang Li, Ruoyu Huang, Haoyu Jiang, Kenan Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Prognostic significance of galectin-1 expression in patients with cancer: a meta-analysis

Rongzu Wu, Tingchun Wu, Kai Wang, Shicheng Luo, Zhen Chen, Min Fan, Dong Xue, Hao Lu, Qianfeng Zhuang, Xianlin Xu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Clinicopathological and prognostic significance of long noncoding RNA MALAT1 in human cancers: a review and meta-analysis

Juan Li, Zhigang Cui, Hang Li, Xiaoting Lv, Min Gao, Zitai Yang, Yanhong Bi, Ziwei Zhang, Shengli Wang, Baosen Zhou, Zhihua Yin

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Clinicopathologic and prognostic significance of VEGF, JAK2 and STAT3 in patients with nasopharyngeal carcinoma

Jin-Zhang Cheng, Jun-Jun Chen, Kai Xue, Zong-Gui Wang, Dan Yu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts

Henry Oppermann, Johannes Dietterle, Katharina Purcz, Markus Morawski, Christian Eisenlöffel, Wolf Müller, Jürgen Meixensberger, Frank Gaunitz

01.12.2018 | Review | Ausgabe 1/2018 Open Access

PEG10 as an oncogene: expression regulatory mechanisms and role in tumor progression

Tian Xie, Shan Pan, Hang Zheng, Zilv Luo, Kingsley M. Tembo, Muhammad Jamal, Zhongyang Yu, Yao Yu, Jing Xia, Qian Yin, Meng Wang, Wen Yuan, Qiuping Zhang, Jie Xiong

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Antitumor activity of arsenite in combination with tetrandrine against human breast cancer cell line MDA-MB-231 in vitro and in vivo

Bo Yuan, Mingjiang Yao, Xiao Wang, Ai Sato, Ayane Okazaki, Hana Komuro, Hideki Hayashi, Hiroo Toyoda, Xiaohua Pei, Xiaomei Hu, Toshihiko Hirano, Norio Takagi

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma

Ming Zhuang, Xubin Qiu, Dong Cheng, Chenlei Zhu, Liang Chen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Clinical significance of serum soluble B7-H3 in patients with osteosarcoma

Ling Wang, Fu-biao Kang, Guo-chuan Zhang, Juan Wang, Ming-fang Xie, Ying-ze Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6

Yuhua Gong, Jinzhong Mao, Di Wu, Xuemei Wang, Long Li, Liang Zhu, Rong Song

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway

Kaihua Ji, Kaili Lin, Yan Wang, Liqing Du, Chang Xu, Ningning He, Jinhan Wang, Yang Liu, Qiang Liu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53

Fei Zhou, Yanhua Zhang, Xiufang Xu, Jingfeng Luo, Fang Yang, Linbo Wang, Shuduo Xie, Jihong Sun, Xiaoming Yang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Prognostic role of neutrophil-to-lymphocyte ratio in diffuse large B cell lymphoma patients: an updated dose–response meta-analysis

Shidai Mu, Lisha Ai, Fengjuan Fan, You Qin, Chunyan Sun, Yu Hu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck

Li She, Yuexiang Qin, Juncheng Wang, Chao Liu, Gangcai Zhu, Guo Li, Ming Wei, Changhan Chen, Guancheng Liu, Diekuo Zhang, Xiyu Chen, Yunyun Wang, Yuanzheng Qiu, Yongquan Tian, Xin Zhang, Yong Liu, Donghai Huang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin

Yibo Dong, Yang Zheng, Chundi Wang, Xu Ding, Yifei Du, Laikui Liu, Wei Zhang, Wei Zhang, Yi Zhong, Yunong Wu, Xiaomeng Song

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Identification of long non-coding RNA competing interactions and biological pathways associated with prognosis in pediatric and adolescent cytogenetically normal acute myeloid leukemia

Xuejiao Yin, Sui Huang, Ruiqi Zhu, Fengjuan Fan, Chunyan Sun, Yu Hu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Prospective clinical study of capecitabine plus oxaliplatin concurrent chemoradiotherapy after radical resection of rectal cancer

Wanghua Chen, Wenling Wang, Yuxin Li, Hongmin Dong, Gang Wang, Xiaokai Li

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3

Yong-Xia Wang, Hui-Fang Zhu, Zhe-Ying Zhang, Feng Ren, Yu-Han Hu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

ZFAS1: a novel tumor-related long non-coding RNA

Dan Dong, Zhongyi Mu, Chenghai Zhao, Mingli Sun

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance

Lujun Chen, Jun Feng, Bin Xu, You Zhou, Xiao Zheng, Changping Wu, Jingting Jiang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Downregulation of hypermethylated in cancer-1 by miR-4532 promotes adriamycin resistance in breast cancer cells

Fan Feng, Xiaolan Zhu, Chunyan Wang, Liang Chen, Weiping Cao, Yueqin Liu, Qi Chen, Wenlin Xu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Sulbactam-enhanced cytotoxicity of doxorubicin in breast cancer cells

Shao-hsuan Wen, Shey-chiang Su, Bo-huang Liou, Cheng-hao Lin, Kuan-rong Lee

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

SOX2OT knockdown derived changes in mitotic regulatory gene network of cancer cells

Marie Saghaeian Jazi, Nader Mansour Samaei, Seyed Javad Mowla, Babak Arefnezhad, Morteza Kouhsar

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effect of dietary components on miRNA and colorectal carcinogenesis

Adewale Oluwaseun Fadaka, Babajide A. Ojo, Olusola Bolaji Adewale, Temitope Esho, Ashley Pretorius

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases

Matteo Fassan, Luca Vianello, Diana Sacchi, Giuseppe N. Fanelli, Giada Munari, Marco Scarpa, Rocco Cappellesso, Fotios Loupakis, Cristiano Lanza, Roberta Salmaso, Claudia Mescoli, Nicola Valeri, Marco Agostini, Edoardo D’Angelo, Sara Lonardi, Salvatore Pucciarelli, Nicola Veronese, Claudio Luchini, Massimo Rugge

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade

Shaoqiang Wang, Yingying Zheng, Zhiwei He, Wolong Zhou, Yuanda Cheng, Chunfang Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Combinational immune-cell therapy of natural killer cells and sorafenib for advanced hepatocellular carcinoma: a review

Faezeh Hosseinzadeh, Javad Verdi, Jafar Ai, Saieh Hajighasemlou, Iman Seyhoun, Frzad Parvizpour, Fatemeh Hosseinzadeh, Abolfazl Iranikhah, Sadegh Shirian

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance

Lujun Chen, Jun Feng, Bin Xu, You Zhou, Xiao Zheng, Changping Wu, Jingting Jiang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies

Evita G. Weagel, Weston Burrup, Roman Kovtun, Edwin J. Velazquez, Abigail M. Felsted, Michelle H. Townsend, Zachary E. Ence, Erica Suh, Stephen R. Piccolo, K. Scott Weber, Richard A. Robison, Kim L. O’Neill

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis

Bianca Maria Scicchitano, Silvia Sorrentino, Gabriella Proietti, Gina Lama, Gabriella Dobrowolny, Angela Catizone, Elena Binda, Luigi Maria Larocca, Gigliola Sica

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Establishment and characterization of a cell line HCS1220 from human liver metastasis of colon cancer

Yi Chai, Huan Wang, Fang Zhou

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

BC094916 suppressed SP 2/0 xenograft tumor by down-regulating Creb1 and Bcl2 transcription

Ruonan Xu, Ying Fang, Chunmei Hou, Bing Zhai, Zhenyu Jiang, Ning Ma, Liang Wang, Gencheng Han, Renxi Wang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Identification of critical genes to predict recurrence and death in colon cancer: integrating gene expression and bioinformatics analysis

Xuan Long, Zhigang Deng, Guoqiang Li, Ziwei Wang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

DNA methylation biomarkers for hepatocellular carcinoma

Guorun Fan, Yaqin Tu, Cai Chen, Haiying Sun, Chidan Wan, Xiong Cai

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

LncRNA SNHG5 promotes the progression of osteosarcoma by sponging the miR-212-3p/SGK3 axis

Cheng Ju, Ruihao Zhou, Jun Sun, Feifei Zhang, Xiaofeng Tang, Kaddie Kwok Chen, Junliang Zhao, Xiaoyong Lan, Shifan Lin, Zhiping Zhang, Xiao-Bin Lv

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Long noncoding RNA ROR promotes breast cancer by regulating the TGF-β pathway

LingLi Hou, Jiancheng Tu, Fangxiong Cheng, Hongwei Yang, Fei Yu, Minghua Wang, Jiubo Liu, Jinbo Fan, Guojun Zhou

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

LncRNA DLX6-AS1 promoted cancer cell proliferation and invasion by attenuating the endogenous function of miR-181b in pancreatic cancer

Yong An, Xue-min Chen, Yong Yang, Feng Mo, Yong Jiang, Dong-lin Sun, Hui-hua Cai

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Decreased RIG-I expression is associated with poor prognosis and promotes cell invasion in human gastric cancer

Lujun Chen, Jun Feng, Shaoxian Wu, Bin Xu, You Zhou, Changping Wu, Jingting Jiang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells

Yang Mu, Na Li, Yu-Lan Cui

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Key elements involved in Epstein–Barr virus-associated gastric cancer and their network regulation

Jing-jing Jing, Ze-yang Wang, Hao Li, Li-ping Sun, Yuan Yuan

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

A drug screening assay on cancer cells chronically adapted to acidosis

Paola Pellegrini, Jason T. Serviss, Thomas Lundbäck, Nicolo Bancaro, Magdalena Mazurkiewicz, Iryna Kolosenko, Di Yu, Martin Haraldsson, Padraig D’Arcy, Stig Linder, Angelo De Milito

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The experimental study of shunt-decompression arterialized vein flap

Zheng Li, Zhen-wei Zhang, Shao-xiao Yu, Jia-chuan Zhuang, Yu-hai Ke, Yi Xiong, Hui-xin Lin, Wen-feng Chen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Marsdenia tenacissima extract induces apoptosis and suppresses autophagy through ERK activation in lung cancer cells

Yan-Na Jiao, Li-Na Wu, Dong Xue, Xi-Juan Liu, Zhi-Hua Tian, Shan-Tong Jiang, Shu-Yan Han, Ping-Ping Li

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Conserved cell populations in doxorubicin-resistant human nasal natural killer/T cell lymphoma cell line: super multidrug resistant cells?

Xudong Zhang, Xiaorui Fu, Meng Dong, Zhenzhen Yang, Shaoxuan Wu, Mijing Ma, Zhaoming Li, Xinhua Wang, Ling Li, Xin Li, Zhenchang Sun, Yu Chang, Feifei Nan, Jiaqin Yan, Yun Mao, Mingzhi Zhang, Qingjiang Chen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Overexpression of LASS2 inhibits proliferation and causes G0/G1 cell cycle arrest in papillary thyroid cancer

Feng Zeng, Liangliang Huang, Xiaoming Cheng, Xiaoli Yang, Taolang Li, Guoli Feng, Yingqi Tang, Yan Yang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Prognostic value of microvessel density in cervical cancer

Xiaoli Hu, Hailing Liu, Miaomiao Ye, Xueqiong Zhu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The predictive and prognostic role of a novel ADS score in esophageal squamous cell carcinoma patients undergoing esophagectomy

Qiu-Fang Gao, Jia-Cong Qiu, Xiao-Hong Huang, Yan-Mei Xu, Shu-Qi Li, Fan Sun, Jing Zhang, Wei-Ming Yang, Qing-Hua Min, Yu-Huan Jiang, Qing-Gen Chen, Lei Zhang, Xiao-Zhong Wang, Hou-Qun Ying

01.12.2018 | Review | Ausgabe 1/2018 Open Access

BORIS: a key regulator of cancer stemness

Sara Soltanian, Hesam Dehghani

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis

Jing Wen, Qian Xu, Yuan Yuan

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells

Si Liu, Kin Pong U, Jieting Zhang, Lai Ling Tsang, Jiawei Huang, Shui Ping Tu, Xiaohua Jiang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

New insights into long noncoding RNAs and pseudogenes in prognosis of renal cell carcinoma

Binghai Chen, Chengyue Wang, Jin Zhang, Yang Zhou, Wei Hu, Tao Guo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Novel molecular insights and new therapeutic strategies in osteosarcoma

Babak Otoukesh, Bahram Boddouhi, Mehdi Moghtadaei, Peyman Kaghazian, Maria Kaghazian

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Somatic mutations in renal cell carcinomas from Chinese patients revealed by whole exome sequencing

Jie Wang, Zhijun Xi, Jianzhong Xi, Hanshuo Zhang, Juan Li, Yuchao Xia, Yuanxue Yi

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

CLDN2 inhibits the metastasis of osteosarcoma cells via down-regulating the afadin/ERK signaling pathway

Xiaowei Zhang, Haiming Wang, Qian Li, Tao Li

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Identification of candidate genes or microRNAs associated with the lymph node metastasis of SCLC

Zhonghao Wang, Bei Lu, Lixin Sun, Xi Yan, Jinzhi Xu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Association of serum follistatin levels with histological types and progression of tumor in human lung cancer

Pengyu Zhang, Yingxin Ruan, Jun Xiao, Fangfang Chen, Xuejun Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

SIRT1 rs3758391 polymorphism and risk of diffuse large B cell lymphoma in a Chinese population

Yutian Kan, Peng Ge, Xinyuan Wang, Gangfeng Xiao, Haifeng Zhao

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Predictive role of UCA1-containing exosomes in cetuximab-resistant colorectal cancer

Ying-nan Yang, Rui Zhang, Jing-wen Du, Heng-heng Yuan, Yan-jing Li, Xiao-li Wei, Xiao-xue Du, Shu-lin Jiang, Yu Han

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC-1 cell apoptosis via activating the mROS-HtrA2/Omi pathways

Jun Wan, Jie Cui, Lei Wang, Kunpeng Wu, Xiaoping Hong, Yulin Zou, Shuang Zhao, Hong Ke

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Prognostic value of Kindlin-2 expression in patients with solid tumors: a meta-analysis

Sheng Liu, Sheng Chen, Kaige Ma, Zengwu Shao

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

An isoform of AIF1 involved in breast cancer

Ferial Amira Slim, Geneviève Ouellette, Kaoutar Ennour-Idrissi, Simon Jacob, Caroline Diorio, Francine Durocher

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer

Dabing Huang, Yong Wang, Yifu He, Gang Wang, Wei Wang, Xinghua Han, Yubei Sun, Lin Lin, Benjie Shan, Guodong Shen, Min Cheng, Geng Bian, Xiang Fang, Shilian Hu, Yueyin Pan

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design

Sumitra Shankar, Ahalya Sreekumar, Deepti Prasad, Ani V. Das, M. Radhakrishna Pillai

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

RPLP1 promotes tumor metastasis and is associated with a poor prognosis in triple-negative breast cancer patients

Zhixian He, Qian Xu, Xi Wang, Jun Wang, Xiangming Mu, Yunhui Cai, Yangyang Qian, Weiwei Shao, Zhimin Shao

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

miR-506 attenuates methylation of lncRNA MEG3 to inhibit migration and invasion of breast cancer cell lines via targeting SP1 and SP3

Xin-Xing Wang, Guang-Cheng Guo, Xue-Ke Qian, Dong-Wei Dou, Zhe Zhang, Xiao-Dong Xu, Xin Duan, Xin-Hong Pei

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Prognostic role of galectin-3 expression in patients with solid tumors: a meta-analysis of 36 eligible studies

Yi Wang, Shiwei Liu, Ye Tian, Yamin Wang, Qijie Zhang, Xiang Zhou, Xianghu Meng, Ninghong Song

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

M3 muscarinic acetylcholine receptors regulate epithelial–mesenchymal transition, perineural invasion, and migration/metastasis in cholangiocarcinoma through the AKT pathway

Yujie Feng, Xiao Hu, Guangwei Liu, Lianfang Lu, Wei Zhao, Fangzhen Shen, Kai Ma, Chuandong Sun, Chengzhan Zhu, Bingyuan Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Integrated whole genome microarray analysis and immunohistochemical assay identifies COL11A1, GJB2 and CTRL as predictive biomarkers for pancreatic cancer

Defeng Sun, Haoyi Jin, Jun Zhang, Xiaodong Tan

01.12.2018 | Commentary | Ausgabe 1/2018 Open Access

Citrate targets FBPase and constitutes an emerging novel approach for cancer therapy

Philippe Icard, Ludovic Fournel, Antoine Coquerel, Joseph Gligorov, Marco Alifano, Hubert Lincet

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

IL-2 augments the sorafenib-induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway

Xiaoyan Ding, Wei Sun, Jinglong Chen

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Predictive significance of TMRPSS2-ERG fusion in prostate cancer: a meta-analysis

Chunjiao Song, Huan Chen

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

Wei Zhang, Jin Li, Yaping Wu, Han Ge, Yue Song, Dongmiao Wang, Hua Yuan, Hongbing Jiang, Yanling Wang, Jie Cheng

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Research progresses in roles of LncRNA and its relationships with breast cancer

Xu Bin, Yang Hongjian, Zhang Xiping, Chen Bo, Yang Shifeng, Tang Binbin

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways

Khaled W. Sadek, Mahmoud Y. Haik, Anas A. Ashour, Tahira Baloch, Tahar Aboulkassim, Amber Yasmeen, Semir Vranic, Asad Zeidan, Ala-Eddin Al Moustafa

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

RelB plays an oncogenic role and conveys chemo-resistance to DLD-1 colon cancer cells

Xiaojun Zhou, Zhili Shan, Hengying Yang, Jingjing Xu, Wenjing Li, Feng Guo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Chimeric antigen receptors: unleashing a new age of anti-cancer therapy

Yan Leyfman

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway

Rong Hu, Ming-qing Wang, Wen-bo Niu, Yan-jing Wang, Yang-yang Liu, Ling-yu Liu, Ming Wang, Juan Zhong, Hai-yan You, Xiao-hui Wu, Ning Deng, Lu Lu, Lian-bo Wei

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

miR-144/451 cluster plays an oncogenic role in esophageal cancer by inhibiting cell invasion

Zhikui Gao, Peng Zhang, Ming Xie, Han Gao, Lihong Yin, Ran Liu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Mifepristone inhibits non-small cell lung carcinoma cellular escape from DNA damaging cisplatin

Heather E. Kapperman, Alicia A. Goyeneche, Carlos M. Telleria

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene

Chunbao Zang, Fangfang Zhao, Lei Hua, Youguang Pu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Increased activated regulatory T cell subsets and aging Treg-like cells in multiple myeloma and monoclonal gammopathy of undetermined significance: a case control study

Ji-nuo Wang, Xin-xin Cao, Ai-lin Zhao, Hao Cai, Xuan Wang, Jian Li

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

A novel non-sulphamoylated 2-methoxyestradiol derivative causes detachment of breast cancer cells by rapid disassembly of focal adhesions

Mandie Botes, Tamarin Jurgens, Zohreh Riahi, Michelle Visagie, Rustelle Janse van Vuuren, Anna Margaretha Joubert, Iman van den Bout

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Thyroid stimulating hormone suppression time on cardiac function of patients with differentiated thyroid carcinoma

Ruihua Wang, Liu Yang, Shui Jin, Xingmin Han, Baoping Liu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Identification of RPL5 and RPL10 as novel diagnostic biomarkers of Atypical teratoid/rhabdoid tumors

Yanming Ren, Chuanyuan Tao, Xiliang Wang, Yan Ju

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Polymorphisms of TGFBR1, TLR4 are associated with prognosis of gastric cancer in a Chinese population

Bangshun He, Tao Xu, Bei Pan, Yuqin Pan, Xuhong Wang, Jingwu Dong, Huiling Sun, Xueni Xu, Xiangxiang Liu, Shukui Wang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Biological indicators of chemoresistance: an ex vivo analysis of γH2AX and p53 expression in feline injection-site sarcomas

Yike Bing, Zacharie Wund, Tina Abratte, Lucia Borlle, Susie Kang, Teresa Southard, Kelly R. Hume

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth

Jin-Feng Zhu, Yi Liu, He Huang, Li Shan, Zhi-Gang Han, Jun-Yuan Liu, Ying-Long Li, Xiang Dong, Wei Zeng

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Exploration of methylation-driven genes for monitoring and prognosis of patients with lung adenocarcinoma

Chundi Gao, Jing Zhuang, Huayao Li, Cun Liu, Chao Zhou, Lijuan Liu, Changgang Sun

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma

Jun-feng Zhang, Jian-shui Zhang, Zhao-hua Zhao, Peng-bo Yang, Sheng-feng Ji, Nan Li, Qin-dong Shi, Jing Tan, Xi Xu, Cang-bao Xu, Ling-yu Zhao

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

Ying Zhang, Kuanyu Wang, Zheng Zhao, Si Sun, Kenan Zhang, Ruoyu Huang, Fan Zeng, Huimin Hu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs

Concetta Paola Ilisso, Donatella Delle Cave, Laura Mosca, Martina Pagano, Alessandra Coppola, Luigi Mele, Michele Caraglia, Giovanna Cacciapuoti, Marina Porcelli

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

MicroRNA-218-5p inhibits cell growth and metastasis in cervical cancer via LYN/NF-κB signaling pathway

Yunsheng Xu, Qin He, Yiyi Lu, Fengxing Tao, Liang Zhao, Rongying Ou

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Upregulation of microRNA 344a-3p is involved in curcumin induced apoptosis in RT4 schwannoma cells

Eun Jung Sohn, Kyoung-mi Bak, Yun-kyeong Nam, Hwan Tae Park

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

ERK-mediated autophagy promotes inactivated Sendai virus (HVJ-E)-induced apoptosis in HeLa cells in an Atg3-dependent manner

Tao Wang, Ning Yu, Miao Qian, Jie Feng, Shuyang Cao, Jun Yin, Quan Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Prognostic impact of pretreatment lymphocyte-to-monocyte ratio in advanced epithelial cancers: a meta-analysis

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01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

TRIM14 promotes colorectal cancer cell migration and invasion through the SPHK1/STAT3 pathway

Zhonghai Jin, Hongguang Li, Xiaofei Hong, Guangrong Ying, Xiaofeng Lu, Lilei Zhuang, Shenbao Wu

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Cellular and clinicopathological features of the IL-33/ST2 axis in human esophageal squamous cell carcinomas

Guanglin Cui, Jingli Ren, Gang Xu, Zhenfeng Li, Wei Zheng, Aping Yuan

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells

Feng Zhang, Chen-Chen Ren, Ling Liu, Yan-Nan Chen, Li Yang, Xiao-An Zhang

01.12.2018 | Hypothesis | Ausgabe 1/2018 Open Access

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01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Identification of biomarkers of chromophobe renal cell carcinoma by weighted gene co-expression network analysis

Xiaomao Yin, Jianfeng Wang, Jin Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Pre-treatment prognostic nutritional index may serve as a potential biomarker in urinary cancers: a systematic review and meta-analysis

Feng Qi, Xiang Zhou, Yi Wang, Yamin Wang, Yichun Wang, Qijie Zhang, Rong Cong, Jie Yang, Ninghong Song

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3

Jianning Yao, Xuexiu Zhang, Jiaheng Li, Dongyao Zhao, Bing Gao, Haining Zhou, Shilin Gao, Lianfeng Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Arenobufagin induces MCF-7 cell apoptosis by promoting JNK-mediated multisite phosphorylation of Yes-associated protein

Li-Juan Deng, Ming Qi, Qun-Long Peng, Min-Feng Chen, Qi Qi, Jia-Yan Zhang, Nan Yao, Mao-Hua Huang, Xiao-Bo Li, Yin-Hui Peng, Jun-Shan Liu, Deng-Rui Fu, Jia-Xu Chen, Wen-Cai Ye, Dong-Mei Zhang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

miRNA-133b targets FGFR1 and presents multiple tumor suppressor activities in osteosarcoma

Gan Gao, Zhen Tian, Huan-Ye Zhu, Xun-Yan Ouyang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Targeting cellular metabolism using rapamycin and/or doxycycline enhances anti-tumour effects in human glioma cells

Gábor Petővári, Zoltán Hujber, Ildikó Krencz, Titanilla Dankó, Noémi Nagy, Fanni Tóth, Regina Raffay, Katalin Mészáros, Hajnalka Rajnai, Enikő Vetlényi, Krisztina Takács-Vellai, András Jeney, Anna Sebestyén

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Prognostic significance of CXCR7 in cancer patients: a meta-analysis

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01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Speckle-type POZ protein functions as a tumor suppressor in non-small cell lung cancer due to DNA methylation

Sumei Yao, Xinming Chen, Jinliang Chen, Yangbo Guan, Yifei Liu, Jianrong Chen, Xuedong Lv

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Analysis of dynamic molecular networks for pancreatic ductal adenocarcinoma progression

Zongfu Pan, Lu Li, Qilu Fang, Yiwen Zhang, Xiaoping Hu, Yangyang Qian, Ping Huang

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Next-generation sequencing-based genetic landscape and its clinical implications for Chinese acute myeloid leukemia patients

Xin-xin Cao, Hao Cai, Yue-ying Mao, Qi Wu, Lu Zhang, Dao-bin Zhou, Jian Li

01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+)

Silvia Gutierrez, M. Danilo Boada

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Immunohistochemical investigation of prognostic biomarkers in resected colorectal liver metastases: a systematic review and meta-analysis

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01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

Analysis of PD-1 related immune transcriptional profile in different cancer types

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01.12.2018 | Primary research | Ausgabe 1/2018 Open Access

An actin-binding protein ESPN is an independent prognosticator and regulates cell growth for esophageal squamous cell carcinoma

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